Investigation of a pathogenic mtDNA microdeletion reveals a translation-dependent deadenylation decay pathway in human mitochondria

Human Molecular Genetics

Volumn 12, Issue 18, 2003, Pages 2341-2348

  Temperley, Richard J ^a   Seneca, Sara H ^b   Tonska, Katarzyna ^c   Bartnik, Ewa ^c   Bindoff, Laurence A ^d   Lightowlers, Robert N ^a   Chrzanowska Lightowlers, Zofia M A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^c UNIVERSITY OF WARSAW   (Poland)

^d UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ADENOSINE TRIPHOSPHATASE; CIS ACTING ELEMENT; CYTOSINE; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RNA; POLYADENYLATED RNA; RIBOSOME RNA; RNA; TRANSFER RNA; TRINUCLEOTIDE;

ACCURACY; ADENYLATION; ARTICLE; CISTRON; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE DELETION; GENETIC STABILITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPOTHESIS; MITOCHONDRION; PATHOGENICITY; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RNA DEGRADATION; RNA PROCESSING; RNA TRANSLATION; STEADY STATE; STOP CODON;

ADENOSINE TRIPHOSPHATASES; CELLS, CULTURED; CODON, TERMINATOR; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; FIBROBLASTS; HUMANS; KINETICS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MODELS, BIOLOGICAL; POLYADENYLATION; PROTEIN BIOSYNTHESIS; RECOMBINANT FUSION PROTEINS; RNA STABILITY; RNA, MESSENGER; SEQUENCE DELETION;

EID: 0141590523     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg238     Document Type: Article

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