Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons

Biochemical Journal

Volumn 377, Issue 3, 2004, Pages 725-731

  Chrzanowska Lightowlers, Zofia M A ^a   Temperley, Richard J ^a   Smith, Paul M ^a   Seneca, Sara H ^b   Lightowlers, Robert N ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

Mitochondrial gene expression; Mitochondrial translation; mt mRNA polyadenylation; mtDNA (mitochondrial DNA) disease; Non stop translation; Termination codon

Indexed keywords

BIOSYNTHESIS; DNA; ENZYMES; GENES; POLYPEPTIDES; RNA;

CODONS; MITOCHONDRIAL MATRIX;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE; MITOCHONDRIAL PROTEIN; POLYPEPTIDE;

ARTICLE; CELL LINE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA TRANSLATION; STEADY STATE; STOP CODON;

EID: 1242314743     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj20031556     Document Type: Article

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