메뉴 건너뛰기




Volumn 26, Issue 2, 2015, Pages 357-366

Upregulation of PD-1 on CD4+CD25+T cells is associated with immunosuppression in liver of mice infected with Echinococcus multilocularis

Author keywords

Echinococcus multilocularis; Infection; PD 1; PD L1; Tregs

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; CD274 PROTEIN, MOUSE; PDCD1 PROTEIN, MOUSE;

EID: 84928630037     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.04.013     Document Type: Article
Times cited : (44)

References (49)
  • 2
    • 84879612219 scopus 로고    scopus 로고
    • Bioinformatic prediction of epitopes in the Emy162 antigen of Echinococcus multilocularis
    • Y.H. Li, X.F. Liu, Y.J. Zhu, X.T. Zhou, and C.B. Cao Bioinformatic prediction of epitopes in the Emy162 antigen of Echinococcus multilocularis Exp. Ther. Med. 6 2013 335 340
    • (2013) Exp. Ther. Med. , vol.6 , pp. 335-340
    • Li, Y.H.1    Liu, X.F.2    Zhu, Y.J.3    Zhou, X.T.4    Cao, C.B.5
  • 3
    • 84878777023 scopus 로고    scopus 로고
    • A systematic review of the literature on cystic echinococcosis frequency worldwide and its associated clinical manifestations
    • C.M. Budke, H. Carabin, P.C. Ndimubanzi, H. Nguyen, and E. Rainwater A systematic review of the literature on cystic echinococcosis frequency worldwide and its associated clinical manifestations Am. J. Trop. Med. Hyg. 88 2013 1011 1027
    • (2013) Am. J. Trop. Med. Hyg. , vol.88 , pp. 1011-1027
    • Budke, C.M.1    Carabin, H.2    Ndimubanzi, P.C.3    Nguyen, H.4    Rainwater, E.5
  • 4
    • 77955550523 scopus 로고    scopus 로고
    • The role of evolutionarily conserved signalling systems in Echinococcus multilocularis development and host-parasite interaction
    • K. Brehm The role of evolutionarily conserved signalling systems in Echinococcus multilocularis development and host-parasite interaction Med. Microbiol. Immunol. 199 2010 247 259
    • (2010) Med. Microbiol. Immunol. , vol.199 , pp. 247-259
    • Brehm, K.1
  • 5
    • 46749144563 scopus 로고    scopus 로고
    • Echinococcus multilocularis: The parasite-host interplay
    • B. Gottstein, and A. Hemphill Echinococcus multilocularis: the parasite-host interplay Exp. Parasitol. 119 2008 447 452
    • (2008) Exp. Parasitol. , vol.119 , pp. 447-452
    • Gottstein, B.1    Hemphill, A.2
  • 6
    • 84855655257 scopus 로고    scopus 로고
    • Hepatocyte proliferation/growth arrest balance in the liver of mice during E. Multilocularis infection: A coordinated 3-stage course
    • C. Zhang, J. Wang, G. Lü, J. Li, and X. Lu Hepatocyte proliferation/growth arrest balance in the liver of mice during E. multilocularis infection: a coordinated 3-stage course PLoS One 7 2012 e30127
    • (2012) PLoS One , vol.7 , pp. e30127
    • Zhang, C.1    Wang, J.2    Lü, G.3    Li, J.4    Lu, X.5
  • 7
    • 80053201945 scopus 로고    scopus 로고
    • Old problems on a new playing field: Helminth zoonoses transmitted among dogs, wildlife, and people in a changing northern climate
    • E.J. Jenkins, J.M. Schurer, and K.M. Gesy Old problems on a new playing field: Helminth zoonoses transmitted among dogs, wildlife, and people in a changing northern climate Vet. Parasitol. 182 2011 54 69
    • (2011) Vet. Parasitol. , vol.182 , pp. 54-69
    • Jenkins, E.J.1    Schurer, J.M.2    Gesy, K.M.3
  • 8
    • 84869211381 scopus 로고    scopus 로고
    • Alveolar echinococcosis: Spectrum of findings at cross-sectional imaging
    • M. Kantarci, U. Bayraktutan, N. Karabulut, B. Aydinli, and H. Ogul Alveolar echinococcosis: spectrum of findings at cross-sectional imaging Radiographics 32 2012 2053 2070
    • (2012) Radiographics , vol.32 , pp. 2053-2070
    • Kantarci, M.1    Bayraktutan, U.2    Karabulut, N.3    Aydinli, B.4    Ogul, H.5
  • 9
    • 84879215734 scopus 로고    scopus 로고
    • Manipulating the PD-1 pathway to improve immunity
    • A.O. Kamphorst, and R. Ahmed Manipulating the PD-1 pathway to improve immunity Curr. Opin. Immunol. 25 2013 381 388
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 381-388
    • Kamphorst, A.O.1    Ahmed, R.2
  • 10
    • 78751583956 scopus 로고    scopus 로고
    • Intraperitoneal Echinococcus multilocularis infection in mice modulates peritoneal CD4 + and CD8 + regulatory T cell development
    • N. Mejri, N. Müller, A. Hemphill, and B. Gottstein Intraperitoneal Echinococcus multilocularis infection in mice modulates peritoneal CD4 + and CD8 + regulatory T cell development Parasitol. Int. 60 2011 45 53
    • (2011) Parasitol. Int. , vol.60 , pp. 45-53
    • Mejri, N.1    Müller, N.2    Hemphill, A.3    Gottstein, B.4
  • 11
    • 84928616628 scopus 로고    scopus 로고
    • Effect of Th17 cells and Treg cells on immune evasion in patients with hepatic hydatid disease
    • T. Turgun, J.Y. Shan, T. LI, R.Y. Lin, and H. Wen Effect of Th17 cells and Treg cells on immune evasion in patients with hepatic hydatid disease Chin. J. Dig. Surg. 9 2010 283 286
    • (2010) Chin. J. Dig. Surg. , vol.9 , pp. 283-286
    • Turgun, T.1    Shan, J.Y.2    Li, T.3    Lin, R.Y.4    Wen, H.5
  • 12
    • 84896704616 scopus 로고    scopus 로고
    • Alveolar echinococcosis: Evaluation of therapeutic strategies
    • D.A. Vuitton, and S. Bresson-Hadni Alveolar echinococcosis: evaluation of therapeutic strategies Expert Opin. Orphan Drugs 2 2014 67 86
    • (2014) Expert Opin. Orphan Drugs , vol.2 , pp. 67-86
    • Vuitton, D.A.1    Bresson-Hadni, S.2
  • 13
    • 84899492035 scopus 로고    scopus 로고
    • Th9/IL-9 profile in human echinococcosis: Their involvement in immune response during infection by echinococcus granulosus
    • N. Pang, F. Zhang, X. Ma, Z. Zhang, and H. Zhao Th9/IL-9 profile in human echinococcosis: their involvement in immune response during infection by echinococcus granulosus Mediat. Inflamm. 2014 2014 781649
    • (2014) Mediat. Inflamm. , vol.2014 , pp. 781649
    • Pang, N.1    Zhang, F.2    Ma, X.3    Zhang, Z.4    Zhao, H.5
  • 15
    • 84863840695 scopus 로고    scopus 로고
    • Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis
    • B. Wilde, F. Hua, S. Dolff, C. Jun, and X. Cai Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis Rheumatology (Oxford) 51 2012 1188 1197
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 1188-1197
    • Wilde, B.1    Hua, F.2    Dolff, S.3    Jun, C.4    Cai, X.5
  • 16
    • 84887832812 scopus 로고    scopus 로고
    • Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients
    • H.B. Jie, N. Gildener-Leapman, J. Li, R.M. Srivastava, and S.P. Gibson Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients Br. J. Cancer 109 2013 2629 2635
    • (2013) Br. J. Cancer , vol.109 , pp. 2629-2635
    • Jie, H.B.1    Gildener-Leapman, N.2    Li, J.3    Srivastava, R.M.4    Gibson, S.P.5
  • 17
    • 17144409086 scopus 로고    scopus 로고
    • PD-L2 + dendritic cells and PD-1 + CD4 + T cells in schistosomiasis correlate with morbidity
    • D.G. Colley, L.E. Sasser, and A.M. Reed PD-L2 + dendritic cells and PD-1 + CD4 + T cells in schistosomiasis correlate with morbidity Parasite Immunol. 27 2005 45 53
    • (2005) Parasite Immunol. , vol.27 , pp. 45-53
    • Colley, D.G.1    Sasser, L.E.2    Reed, A.M.3
  • 18
    • 84868602945 scopus 로고    scopus 로고
    • Herpesvirus exploitation of host immune inhibitory pathways
    • G. Stack, M.A. Stacey, and I.R. Humphreys Herpesvirus exploitation of host immune inhibitory pathways Viruses 4 2012 1182 1201
    • (2012) Viruses , vol.4 , pp. 1182-1201
    • Stack, G.1    Stacey, M.A.2    Humphreys, I.R.3
  • 19
    • 79959357729 scopus 로고    scopus 로고
    • Control of toxoplasma reactivation by rescue of dysfunctional CD8 + T-cell response via PD-1-PDL-1 blockade
    • R. Bhadra, J.P. Gigley, L.M. Weiss, and I.A. Khan Control of toxoplasma reactivation by rescue of dysfunctional CD8 + T-cell response via PD-1-PDL-1 blockade Proc. Natl. Acad. Sci. U. S. A. 108 2011 9196 9201
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 9196-9201
    • Bhadra, R.1    Gigley, J.P.2    Weiss, L.M.3    Khan, I.A.4
  • 20
    • 84886948036 scopus 로고    scopus 로고
    • B7 family checkpoint regulators in immune regulation and disease
    • S. Ceeraz, E.C. Nowak, and R.J. Noelle B7 family checkpoint regulators in immune regulation and disease Trends Immunol. 34 2013 556 563
    • (2013) Trends Immunol. , vol.34 , pp. 556-563
    • Ceeraz, S.1    Nowak, E.C.2    Noelle, R.J.3
  • 21
    • 84886502709 scopus 로고    scopus 로고
    • Programmed death 1 and programmed death ligand 1 expressions in patients with chronic hepatitis B
    • W.J. Zhang, C.H. Peng, and S.S. Zheng Programmed death 1 and programmed death ligand 1 expressions in patients with chronic hepatitis B Hepatobiliary Pancreat. Dis. Int. 12 2013 394 399
    • (2013) Hepatobiliary Pancreat. Dis. Int. , vol.12 , pp. 394-399
    • Zhang, W.J.1    Peng, C.H.2    Zheng, S.S.3
  • 22
    • 78650369297 scopus 로고    scopus 로고
    • PD-1-PD-L1 pathway impairs T(h)1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guérin
    • S. Sakai, I. Kawamura, T. Okazaki, K. Tsuchiya, and R. Uchiyama PD-1-PD-L1 pathway impairs T(h)1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guérin Int. Immunol. 22 2010 915 925
    • (2010) Int. Immunol. , vol.22 , pp. 915-925
    • Sakai, S.1    Kawamura, I.2    Okazaki, T.3    Tsuchiya, K.4    Uchiyama, R.5
  • 23
    • 77949461871 scopus 로고    scopus 로고
    • Making antigen invisible: A coinhibitory molecule regulates the interaction between T cells and dendritic cells
    • H. Diepolder, and R. Obst Making antigen invisible: a coinhibitory molecule regulates the interaction between T cells and dendritic cells Expert Rev. Vaccines 9 2010 243 247
    • (2010) Expert Rev. Vaccines , vol.9 , pp. 243-247
    • Diepolder, H.1    Obst, R.2
  • 24
    • 84871844273 scopus 로고    scopus 로고
    • In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4 + T cell levels in humanized mice
    • B.E. Palmer, C.P. Neff, J. Lecureux, A. Ehler, and M. Dsouza In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4 + T cell levels in humanized mice J. Immunol. 190 2013 211 219
    • (2013) J. Immunol. , vol.190 , pp. 211-219
    • Palmer, B.E.1    Neff, C.P.2    Lecureux, J.3    Ehler, A.4    Dsouza, M.5
  • 25
    • 84873478163 scopus 로고    scopus 로고
    • Blockade of programmed death receptor-1 signaling restores expression of mostly proinflammatory cytokines in anergic cytomegalovirus-specific T cells
    • J. Dirks, A. Egli, U. Sester, M. Sester, and H.H. Hirsch Blockade of programmed death receptor-1 signaling restores expression of mostly proinflammatory cytokines in anergic cytomegalovirus-specific T cells Transpl. Infect. Dis. 15 2013 79 89
    • (2013) Transpl. Infect. Dis. , vol.15 , pp. 79-89
    • Dirks, J.1    Egli, A.2    Sester, U.3    Sester, M.4    Hirsch, H.H.5
  • 26
    • 84983720423 scopus 로고    scopus 로고
    • PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model
    • H.T. Tzeng, H.F. Tsai, H.J. Liao, Y.J. Lin, and L. Chen PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model PLoS One 7 2012 e39179
    • (2012) PLoS One , vol.7 , pp. e39179
    • Tzeng, H.T.1    Tsai, H.F.2    Liao, H.J.3    Lin, Y.J.4    Chen, L.5
  • 27
    • 84860584561 scopus 로고    scopus 로고
    • PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques
    • R. Dyavar Shetty, V. Velu, K. Titanji, S.E. Bosinger, and G.J. Freeman PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques J. Clin. Invest. 122 2012 1712 1716
    • (2012) J. Clin. Invest. , vol.122 , pp. 1712-1716
    • Dyavar Shetty, R.1    Velu, V.2    Titanji, K.3    Bosinger, S.E.4    Freeman, G.J.5
  • 28
    • 79955576855 scopus 로고    scopus 로고
    • Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation
    • D.X. Bu, M. Tarrio, E. Maganto-Garcia, G. Stavrakis, and G. Tajima Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation Arterioscler. Thromb. Vasc. Biol. 31 2011 1100 1107
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1100-1107
    • Bu, D.X.1    Tarrio, M.2    Maganto-Garcia, E.3    Stavrakis, G.4    Tajima, G.5
  • 29
    • 3142750528 scopus 로고    scopus 로고
    • Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
    • P. Smith, C.M. Walsh, N.E. Mangan, R.E. Fallon, and J.R. Sayers Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages J. Immunol. 173 2004 1240 1248
    • (2004) J. Immunol. , vol.173 , pp. 1240-1248
    • Smith, P.1    Walsh, C.M.2    Mangan, N.E.3    Fallon, R.E.4    Sayers, J.R.5
  • 30
    • 84888334003 scopus 로고    scopus 로고
    • Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function
    • K.J. Esch, R. Juelsgaard, P.A. Martinez, D.E. Jones, and C.A. Petersen Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function J. Immunol. 191 2013 5542 5550
    • (2013) J. Immunol. , vol.191 , pp. 5542-5550
    • Esch, K.J.1    Juelsgaard, R.2    Martinez, P.A.3    Jones, D.E.4    Petersen, C.A.5
  • 31
    • 84875455887 scopus 로고    scopus 로고
    • Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4 + T cell exhaustion
    • Z. Mou, H.M. Muleme, D. Liu, P. Jia, and I.B. Okwor Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4 + T cell exhaustion J. Immunol. 190 2013 3380 3389
    • (2013) J. Immunol. , vol.190 , pp. 3380-3389
    • Mou, Z.1    Muleme, H.M.2    Liu, D.3    Jia, P.4    Okwor, I.B.5
  • 32
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction
    • L. Trautmann, L. Janbazian, N. Chomont, E.A. Said, and S. Gimmig Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction Nat. Med. 12 2006 1198 1202
    • (2006) Nat. Med. , vol.12 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3    Said, E.A.4    Gimmig, S.5
  • 33
    • 84879804595 scopus 로고    scopus 로고
    • Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia
    • W. Yang, Y. Song, Y.L. Lu, J.Z. Sun, and H.W. Wang Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia Immunology 139 2013 513 522
    • (2013) Immunology , vol.139 , pp. 513-522
    • Yang, W.1    Song, Y.2    Lu, Y.L.3    Sun, J.Z.4    Wang, H.W.5
  • 34
    • 84863989706 scopus 로고    scopus 로고
    • Programmed death 1 expression as a marker for immune and physiological dysfunction in the critically ill surgical patient
    • S.F. Monaghan, R.K. Thakkar, M.L. Tran, X. Huang, and W.G. Cioffi Programmed death 1 expression as a marker for immune and physiological dysfunction in the critically ill surgical patient Shock 38 2012 117 122
    • (2012) Shock , vol.38 , pp. 117-122
    • Monaghan, S.F.1    Thakkar, R.K.2    Tran, M.L.3    Huang, X.4    Cioffi, W.G.5
  • 35
    • 84880758206 scopus 로고    scopus 로고
    • Changes in the balance between Treg and Th17 cells in patients with chronic hepatitis B
    • Z.J. Su, X.P. Yu, R.Y. Guo, D.S. Ming, and L.Y. Huang Changes in the balance between Treg and Th17 cells in patients with chronic hepatitis B Diagn. Microbiol. Infect. Dis. 76 2013 437 444
    • (2013) Diagn. Microbiol. Infect. Dis. , vol.76 , pp. 437-444
    • Su, Z.J.1    Yu, X.P.2    Guo, R.Y.3    Ming, D.S.4    Huang, L.Y.5
  • 36
    • 84872743632 scopus 로고    scopus 로고
    • Frequency of T-cell FoxP3 + Treg and CD4 +/CD8 + PD-1 expression is related to HBeAg seroconversion in hepatitis B patients on pegylated interferon
    • H. Ma, H.H. Zhang, and L. Wei Frequency of T-cell FoxP3 + Treg and CD4 +/CD8 + PD-1 expression is related to HBeAg seroconversion in hepatitis B patients on pegylated interferon Chin. Med. J. (Engl.) 126 2013 267 273
    • (2013) Chin. Med. J. (Engl.) , vol.126 , pp. 267-273
    • Ma, H.1    Zhang, H.H.2    Wei, L.3
  • 37
    • 84876099272 scopus 로고    scopus 로고
    • Minimum alveolar concentration: Ongoing relevance and clinical utility
    • A. Aranake, G.A. Mashour, and M.S. Avidan Minimum alveolar concentration: ongoing relevance and clinical utility Anaesthesia 68 2013 512 522
    • (2013) Anaesthesia , vol.68 , pp. 512-522
    • Aranake, A.1    Mashour, G.A.2    Avidan, M.S.3
  • 38
    • 84897471565 scopus 로고    scopus 로고
    • TGF-β/Smad signaling pathway regulates Th17/Treg balance during Echinococcus multilocularis infection
    • N. Pang, F. Zhang, X. Ma, Y. Zhu, and H. Zhao TGF-β/Smad signaling pathway regulates Th17/Treg balance during Echinococcus multilocularis infection Int. Immunopharmacol. 20 2014 248 257
    • (2014) Int. Immunopharmacol. , vol.20 , pp. 248-257
    • Pang, N.1    Zhang, F.2    Ma, X.3    Zhu, Y.4    Zhao, H.5
  • 39
    • 84859407349 scopus 로고    scopus 로고
    • Immune suppression in premalignant respiratory papillomas: Enriched functional CD4 + Foxp3 + regulatory T cells and PD-1/PD-L1/L2 expression
    • L.J. Hatam, J.A. DeVoti, D.W. Rosenthal, F. Lam, and A.L. Abramson Immune suppression in premalignant respiratory papillomas: enriched functional CD4 + Foxp3 + regulatory T cells and PD-1/PD-L1/L2 expression Clin. Cancer Res. 18 2012 1925 1935
    • (2012) Clin. Cancer Res. , vol.18 , pp. 1925-1935
    • Hatam, L.J.1    Devoti, J.A.2    Rosenthal, D.W.3    Lam, F.4    Abramson, A.L.5
  • 40
    • 84866003112 scopus 로고    scopus 로고
    • Echinococcus alveolaris: Presenting as a cerebral metastasis
    • N.G. Ozdemir, A. Kurt, D.N. Binici, and K.M. Ozsoy Echinococcus alveolaris: presenting as a cerebral metastasis Turk. Neurosurg. 22 2012 448 451
    • (2012) Turk. Neurosurg. , vol.22 , pp. 448-451
    • Ozdemir, N.G.1    Kurt, A.2    Binici, D.N.3    Ozsoy, K.M.4
  • 41
    • 0033864189 scopus 로고    scopus 로고
    • Resistance/susceptibility to Echinococcus multilocularis infection any cytokine profile in humans.II. Influence of the HLA B8, DR3, and DQ2 haplotype
    • V. Godot, S. Harraga, I. Beurton, P. Tiberghien, and E. Sarciron Resistance/susceptibility to Echinococcus multilocularis infection any cytokine profile in humans.II. Influence of the HLA B8, DR3, and DQ2 haplotype Clin. Exp. Immunol. 121 2000 491 498
    • (2000) Clin. Exp. Immunol. , vol.121 , pp. 491-498
    • Godot, V.1    Harraga, S.2    Beurton, I.3    Tiberghien, P.4    Sarciron, E.5
  • 42
    • 84857402937 scopus 로고    scopus 로고
    • Therapeutic intervention in cancer and chronic viral infection: Antibody mediated manipulation of PD-1/PD-L1 interaction
    • P. Sakthivel, M. Gereke, and D. Bruder Therapeutic intervention in cancer and chronic viral infection: antibody mediated manipulation of PD-1/PD-L1 interaction Rev. Recent Clin. Trials 7 2012 10 23
    • (2012) Rev. Recent Clin. Trials , vol.7 , pp. 10-23
    • Sakthivel, P.1    Gereke, M.2    Bruder, D.3
  • 43
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • H. Dong, G. Zhu, K. Tamada, and L. Chen B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion Nat. Med. 5 1999 1365 1369
    • (1999) Nat. Med. , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 45
    • 84893602341 scopus 로고    scopus 로고
    • Staphylococcus aureus convert neonatal conventional CD4 + T cells into FOXP3 + CD25 + CD127low T cells via the PD-1/PD-L1 axis
    • H. Rabe, I. Nordström, K. Andersson, A.C. Lundell, and A. Rudin Staphylococcus aureus convert neonatal conventional CD4 + T cells into FOXP3 + CD25 + CD127low T cells via the PD-1/PD-L1 axis Immunology 141 2014 467 481
    • (2014) Immunology , vol.141 , pp. 467-481
    • Rabe, H.1    Nordström, I.2    Andersson, K.3    Lundell, A.C.4    Rudin, A.5
  • 46
    • 84891840810 scopus 로고    scopus 로고
    • Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway
    • S.M. Ahmad, S.K. Larsen, I.M. Svane, and M.H. Andersen Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway Leukemia 28 2014 236 238
    • (2014) Leukemia , vol.28 , pp. 236-238
    • Ahmad, S.M.1    Larsen, S.K.2    Svane, I.M.3    Andersen, M.H.4
  • 47
    • 84904855312 scopus 로고    scopus 로고
    • Immunologic and clinical effects of targeting PD-1 in lung cancer
    • R.D. Harvey Immunologic and clinical effects of targeting PD-1 in lung cancer Clin. Pharmacol. Ther. 96 2014 214 223
    • (2014) Clin. Pharmacol. Ther. , vol.96 , pp. 214-223
    • Harvey, R.D.1
  • 48
    • 79957953513 scopus 로고    scopus 로고
    • Characteristics and PD-1 expression of peripheral CD4 + CD127loCD25hiFoxP3 + Treg cells in chronic HCV infected-patients
    • T. Shen, J. Zheng, H. Liang, C. Xu, and X. Chen Characteristics and PD-1 expression of peripheral CD4 + CD127loCD25hiFoxP3 + Treg cells in chronic HCV infected-patients Virol. J. 8 2011 279 287
    • (2011) Virol. J. , vol.8 , pp. 279-287
    • Shen, T.1    Zheng, J.2    Liang, H.3    Xu, C.4    Chen, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.