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Volumn 195, Issue 2, 2015, Pages 541-549

Murine lung cancer induces generalized T-cell exhaustion

Author keywords

Immune dysregulation; Immunology; Inflammation; T lymphocyte

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; LIPOCORTIN 5; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; BTLA PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; PDCD1 PROTEIN, MOUSE;

EID: 84928592143     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2015.02.004     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 0037137510 scopus 로고    scopus 로고
    • HLA class i antigen loss, tumor immune escape and immune selection
    • M. Campoli, C.C. Chang, and S. Ferrone HLA class I antigen loss, tumor immune escape and immune selection Vaccine 20 Suppl 4 2002 A40
    • (2002) Vaccine , vol.20 , pp. A40
    • Campoli, M.1    Chang, C.C.2    Ferrone, S.3
  • 2
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • M.J. Smyth, G.P. Dunn, and R.D. Schreiber Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity Adv Immunol 90 2006 1
    • (2006) Adv Immunol , vol.90 , pp. 1
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 3
    • 79959549102 scopus 로고    scopus 로고
    • Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer
    • J. Krempski, L. Karyampudi, and M.D. Behrens Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer J Immunol 186 2011 6905
    • (2011) J Immunol , vol.186 , pp. 6905
    • Krempski, J.1    Karyampudi, L.2    Behrens, M.D.3
  • 6
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • E.J. Wherry T cell exhaustion Nat Immunol 12 2011 492
    • (2011) Nat Immunol , vol.12 , pp. 492
    • Wherry, E.J.1
  • 7
    • 84900450382 scopus 로고    scopus 로고
    • Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy
    • R. Mittal, M. Wagener, and E.R. Breed Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy PLoS One 9 2014 e93523
    • (2014) PLoS One , vol.9 , pp. e93523
    • Mittal, R.1    Wagener, M.2    Breed, E.R.3
  • 8
    • 5644275041 scopus 로고    scopus 로고
    • Do not get sick when you are sick: The impact of comorbid conditions
    • D.G. Remick Do not get sick when you are sick: the impact of comorbid conditions Crit Care Med 32 2004 2147
    • (2004) Crit Care Med , vol.32 , pp. 2147
    • Remick, D.G.1
  • 9
    • 19444388216 scopus 로고    scopus 로고
    • Hospitalized cancer patients with severe sepsis: Analysis of incidence, mortality, and associated costs of care
    • M.D. Williams, L.A. Braun, and L.M. Cooper Hospitalized cancer patients with severe sepsis: analysis of incidence, mortality, and associated costs of care Crit Care 8 2004 R291
    • (2004) Crit Care , vol.8 , pp. R291
    • Williams, M.D.1    Braun, L.A.2    Cooper, L.M.3
  • 10
    • 33745146498 scopus 로고    scopus 로고
    • The epidemiology of sepsis in patients with malignancy
    • P.A. Danai, M. Moss, D.M. Mannino, and G.S. Martin The epidemiology of sepsis in patients with malignancy Chest 129 2006 1432
    • (2006) Chest , vol.129 , pp. 1432
    • Danai, P.A.1    Moss, M.2    Mannino, D.M.3    Martin, G.S.4
  • 11
    • 77249138225 scopus 로고    scopus 로고
    • Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis
    • A.C. Fox, C.M. Robertson, and B. Belt Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis Crit Care Med 38 2010 886
    • (2010) Crit Care Med , vol.38 , pp. 886
    • Fox, A.C.1    Robertson, C.M.2    Belt, B.3
  • 12
    • 57849168934 scopus 로고    scopus 로고
    • Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
    • S.D. Blackburn, H. Shin, and W.N. Haining Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection Nat Immunol 10 2009 29
    • (2009) Nat Immunol , vol.10 , pp. 29
    • Blackburn, S.D.1    Shin, H.2    Haining, W.N.3
  • 13
    • 4143149381 scopus 로고    scopus 로고
    • Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: Tumor escape by antigen loss and loss of MHC expression
    • H.T. Khong, Q.J. Wang, and S.A. Rosenberg Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: tumor escape by antigen loss and loss of MHC expression J Immunother 27 2004 184
    • (2004) J Immunother , vol.27 , pp. 184
    • Khong, H.T.1    Wang, Q.J.2    Rosenberg, S.A.3
  • 14
    • 84886943825 scopus 로고    scopus 로고
    • HLA class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
    • H.H. Schmidt, Y. Ge, and F.J. Hartmann HLA class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients Oncoimmunology 2 2013 e24962
    • (2013) Oncoimmunology , vol.2 , pp. e24962
    • Schmidt, H.H.1    Ge, Y.2    Hartmann, F.J.3
  • 15
    • 84886040918 scopus 로고    scopus 로고
    • Specific recruitment of gamma delta regulatory T cells in human breast cancer
    • J. Ye, C. Ma, and F. Wang Specific recruitment of gamma delta regulatory T cells in human breast cancer Cancer Res 73 2013 6137
    • (2013) Cancer Res , vol.73 , pp. 6137
    • Ye, J.1    Ma, C.2    Wang, F.3
  • 16
    • 77953337676 scopus 로고    scopus 로고
    • Inhibiting the inhibitors: Evaluating agents targeting cancer immunosuppression
    • T.L. Whiteside Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression Expert Opin Biol Ther 10 2010 1019
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 1019
    • Whiteside, T.L.1
  • 17
    • 36048959304 scopus 로고    scopus 로고
    • Tumor microenvironment and immune escape
    • viii
    • S. Ferrone, and T.L. Whiteside Tumor microenvironment and immune escape Surg Oncol Clin N Am 16 2007 755 viii
    • (2007) Surg Oncol Clin N Am , vol.16 , pp. 755
    • Ferrone, S.1    Whiteside, T.L.2
  • 18
    • 84874108466 scopus 로고    scopus 로고
    • Chemoimmunotherapy: Reengineering tumor immunity
    • G. Chen, and L.A. Emens Chemoimmunotherapy: reengineering tumor immunity Cancer Immunol Immunother 62 2013 203
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 203
    • Chen, G.1    Emens, L.A.2
  • 19
    • 84876993950 scopus 로고    scopus 로고
    • Normalizing tumor microenvironment to treat cancer: Bench to bedside to biomarkers
    • R.K. Jain Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers J Clin Oncol 31 2013 2205
    • (2013) J Clin Oncol , vol.31 , pp. 2205
    • Jain, R.K.1
  • 20
    • 84877828533 scopus 로고    scopus 로고
    • Harnessing the antigenic fingerprint of each individual cancer for immunotherapy of human cancer: Genomics shows a new way and its challenges
    • P.K. Srivastava, and F. Duan Harnessing the antigenic fingerprint of each individual cancer for immunotherapy of human cancer: genomics shows a new way and its challenges Cancer Immunol Immunother: CII 62 2013 967
    • (2013) Cancer Immunol Immunother: CII , vol.62 , pp. 967
    • Srivastava, P.K.1    Duan, F.2
  • 21
    • 74949088573 scopus 로고    scopus 로고
    • Putting the brakes on BTLA in T cell-mediated cancer immunotherapy
    • C.M. Paulos, and C.H. June Putting the brakes on BTLA in T cell-mediated cancer immunotherapy J Clin Invest 120 2010 76
    • (2010) J Clin Invest , vol.120 , pp. 76
    • Paulos, C.M.1    June, C.H.2
  • 22
    • 84862841841 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation
    • W. Hobo, W.J. Norde, and N. Schaap B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation J Immunol (Baltimore, Md: 1950) 189 2012 39
    • (2012) J Immunol (Baltimore, Md: 1950) , vol.189 , pp. 39
    • Hobo, W.1    Norde, W.J.2    Schaap, N.3
  • 23
    • 84921823501 scopus 로고    scopus 로고
    • Programmed death 1 and B and T lymphocyte attenuator immunoreceptors and their association with malignant T-lymphoproliferative disorders: Brief review
    • S. Karakatsanis, G. Bertsias, P. Roussou, and D. Boumpas Programmed death 1 and B and T lymphocyte attenuator immunoreceptors and their association with malignant T-lymphoproliferative disorders: brief review Hematol Oncol 32 2014 113
    • (2014) Hematol Oncol , vol.32 , pp. 113
    • Karakatsanis, S.1    Bertsias, G.2    Roussou, P.3    Boumpas, D.4
  • 24
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation
    • B. Bengsch, B. Seigel, and M. Ruhl Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation PLoS Pathog 6 2010 e1000947
    • (2010) PLoS Pathog , vol.6 , pp. e1000947
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3
  • 25
    • 84863393290 scopus 로고    scopus 로고
    • CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
    • J. Fourcade, Z. Sun, and O. Pagliano CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1 Cancer Res 72 2012 887
    • (2012) Cancer Res , vol.72 , pp. 887
    • Fourcade, J.1    Sun, Z.2    Pagliano, O.3
  • 26
    • 84883863501 scopus 로고    scopus 로고
    • Up-regulation of PD-L1, IDO, and Tregs in the melanoma tumor microenvironment is driven by CD8+ T cells
    • S. Spranger, R.M. Spaapen, and Y. Zha Up-regulation of PD-L1, IDO, and Tregs in the melanoma tumor microenvironment is driven by CD8+ T cells Sci Transl Med 5 2013 200ra116
    • (2013) Sci Transl Med , vol.5 , pp. 200ra116
    • Spranger, S.1    Spaapen, R.M.2    Zha, Y.3
  • 27
    • 65549084772 scopus 로고    scopus 로고
    • PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
    • X. Huang, F. Venet, and Y.L. Wang PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis Proc Natl Acad Sci U S A 106 2009 6303
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6303
    • Huang, X.1    Venet, F.2    Wang, Y.L.3
  • 28
    • 84865457276 scopus 로고    scopus 로고
    • BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction
    • N.J. Shubin, C.S. Chung, D.S. Heffernan, L.R. Irwin, S.F. Monaghan, and A. Ayala BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction J Leukoc Biol 92 2012 593
    • (2012) J Leukoc Biol , vol.92 , pp. 593
    • Shubin, N.J.1    Chung, C.S.2    Heffernan, D.S.3    Irwin, L.R.4    Monaghan, S.F.5    Ayala, A.6
  • 29
    • 84891510610 scopus 로고    scopus 로고
    • Targeting the programmed cell death 1: Programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis
    • K. Chang, C. Svabek, and C. Vazquez-Guillamet Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis Crit Care 18 2014 R3
    • (2014) Crit Care , vol.18 , pp. R3
    • Chang, K.1    Svabek, C.2    Vazquez-Guillamet, C.3
  • 30
    • 84897378109 scopus 로고    scopus 로고
    • The new normal: Immunomodulatory agents against sepsis immune suppression
    • N.A. Hutchins, J. Unsinger, R.S. Hotchkiss, and A. Ayala The new normal: immunomodulatory agents against sepsis immune suppression Trends Mol Med 20 2014 224
    • (2014) Trends Mol Med , vol.20 , pp. 224
    • Hutchins, N.A.1    Unsinger, J.2    Hotchkiss, R.S.3    Ayala, A.4
  • 31
    • 66149123225 scopus 로고    scopus 로고
    • Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection
    • J.N. Blattman, E.J. Wherry, S.J. Ha, R.G. van der Most, and R. Ahmed Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection J Virol 83 2009 4386
    • (2009) J Virol , vol.83 , pp. 4386
    • Blattman, J.N.1    Wherry, E.J.2    Ha, S.J.3    Van Der Most, R.G.4    Ahmed, R.5
  • 32
    • 79957661532 scopus 로고    scopus 로고
    • Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1(+)/CD127(-) HCV-specific CD8(+) cells targeting the virus in chronic hepatitis C virus infection
    • J.R. Larrubia, S. Benito-Martinez, and J. Miquel Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1(+)/CD127(-) HCV-specific CD8(+) cells targeting the virus in chronic hepatitis C virus infection Cell Immunol 269 2011 104
    • (2011) Cell Immunol , vol.269 , pp. 104
    • Larrubia, J.R.1    Benito-Martinez, S.2    Miquel, J.3
  • 33
    • 84873372202 scopus 로고    scopus 로고
    • Advances in targeting cell surface signalling molecules for immune modulation
    • S. Yao, Y. Zhu, and L. Chen Advances in targeting cell surface signalling molecules for immune modulation Nat Rev Drug Discov 12 2013 130
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 130
    • Yao, S.1    Zhu, Y.2    Chen, L.3
  • 34
    • 11844292050 scopus 로고    scopus 로고
    • Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells
    • S.V. Vaidya, S.E. Stepp, and M.E. McNerney Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells J Immunol 174 2005 800
    • (2005) J Immunol , vol.174 , pp. 800
    • Vaidya, S.V.1    Stepp, S.E.2    McNerney, M.E.3
  • 35
    • 79958097537 scopus 로고    scopus 로고
    • 2B4 (CD244) signaling via chimeric receptors costimulates tumor-antigen specific proliferation and in vitro expansion of human T cells
    • B. Altvater, S. Landmeier, and S. Pscherer 2B4 (CD244) signaling via chimeric receptors costimulates tumor-antigen specific proliferation and in vitro expansion of human T cells Cancer Immunol Immunother: CII 58 2009 1991
    • (2009) Cancer Immunol Immunother: CII , vol.58 , pp. 1991
    • Altvater, B.1    Landmeier, S.2    Pscherer, S.3
  • 36
    • 84893732562 scopus 로고    scopus 로고
    • 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses
    • D. Liu, S.M. Krummey, and I.R. Badell 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses J Exp Med 211 2014 297
    • (2014) J Exp Med , vol.211 , pp. 297
    • Liu, D.1    Krummey, S.M.2    Badell, I.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.