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Volumn 9, Issue 5, 2014, Pages

Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR 2B4; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN BTLA; UNCLASSIFIED DRUG; BTLA PROTEIN, MOUSE; CD244 PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; PDCD1 PROTEIN, MOUSE;

EID: 84900450382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093523     Document Type: Article
Times cited : (24)

References (47)
  • 1
    • 84856375893 scopus 로고    scopus 로고
    • Roles of the immune system in skin cancer
    • Rangwala S, Tsai KY (2011) Roles of the immune system in skin cancer. Br J Dermatol 165: 953-965.
    • (2011) Br J Dermatol , vol.165 , pp. 953-965
    • Rangwala, S.1    Tsai, K.Y.2
  • 2
    • 33646755569 scopus 로고    scopus 로고
    • Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
    • DOI 10.1016/S0065-2776(06)90001-7, PII S0065277606900017
    • Smyth MJ, Dunn GP, Schreiber RD (2006) Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv Immunol 90: 1-50. (Pubitemid 43765795)
    • (2006) Advances in Immunology , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 4
    • 85027949846 scopus 로고    scopus 로고
    • Prognostic impact of anticancer immune responses: An introduction
    • Pages F, Kroemer G (2011) Prognostic impact of anticancer immune responses: an introduction. Semin Immunopathol 33: 317-319.
    • (2011) Semin Immunopathol , vol.33 , pp. 317-319
    • Pages, F.1    Kroemer, G.2
  • 5
    • 0037137510 scopus 로고    scopus 로고
    • HLA class I antigen loss, tumor immune escape and immune selection
    • DOI 10.1016/S0264-410X(02)00386-9, PII S0264410X02003869
    • Campoli M, Chang CC, Ferrone S (2002) HLA class I antigen loss, tumor immune escape and immune selection. Vaccine 20 Suppl 4: A40-45. (Pubitemid 35449404)
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 4
    • Campoli, M.1    Chang, C.-C.2    Ferrone, S.3
  • 7
    • 4143149381 scopus 로고    scopus 로고
    • Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: Tumor escape by antigen loss and loss of MHC expression
    • Khong HT, Wang QJ, Rosenberg SA (2004) Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: tumor escape by antigen loss and loss of MHC expression. J Immunother 27: 184-190. (Pubitemid 39118082)
    • (2004) Journal of Immunotherapy , vol.27 , Issue.3 , pp. 184-190
    • Khong, H.T.1    Wang, Q.J.2    Rosenberg, S.A.3
  • 8
    • 36048959304 scopus 로고    scopus 로고
    • Tumor Microenvironment and Immune Escape
    • DOI 10.1016/j.soc.2007.08.004, PII S1055320707000981, Tumor Immunology for the Practicing Surgeon
    • Ferrone S, Whiteside TL (2007) Tumor microenvironment and immune escape. Surg Oncol Clin N Am 16: 755-774, viii. (Pubitemid 350101281)
    • (2007) Surgical Oncology Clinics of North America , vol.16 , Issue.4 , pp. 755-774
    • Ferrone, S.1    Whiteside, T.L.2
  • 9
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry EJ (2011) T cell exhaustion. Nat Immunol 12: 492-499.
    • (2011) Nat Immunol , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 10
    • 57849168934 scopus 로고    scopus 로고
    • Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
    • Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, et al. (2009) Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol 10: 29-37.
    • (2009) Nat Immunol , vol.10 , pp. 29-37
    • Blackburn, S.D.1    Shin, H.2    Haining, W.N.3    Zou, T.4    Workman, C.J.5
  • 11
    • 79959549102 scopus 로고    scopus 로고
    • Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer
    • Krempski J, Karyampudi L, Behrens MD, Erskine CL, Hartmann L, et al. (2011) Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer. J Immunol 186: 6905-6913.
    • (2011) J Immunol , vol.186 , pp. 6905-6913
    • Krempski, J.1    Karyampudi, L.2    Behrens, M.D.3    Erskine, C.L.4    Hartmann, L.5
  • 12
    • 84863393290 scopus 로고    scopus 로고
    • CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
    • Fourcade J, Sun Z, Pagliano O, Guillaume P, Luescher IF, et al. (2012) CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Res 72: 887-896.
    • (2012) Cancer Res , vol.72 , pp. 887-896
    • Fourcade, J.1    Sun, Z.2    Pagliano, O.3    Guillaume, P.4    Luescher, I.F.5
  • 13
    • 84886443514 scopus 로고    scopus 로고
    • CTLA-4 and PD-1/PD-L1 blockade: New immunotherapeutic modalities with durable clinical benefit in melanoma patients
    • Ott PA, Hodi FS, Robert C (2013) CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patients. Clin Cancer Res 19: 5300-5309.
    • (2013) Clin Cancer Res , vol.19 , pp. 5300-5309
    • Ott, P.A.1    Hodi, F.S.2    Robert, C.3
  • 14
    • 84886040918 scopus 로고    scopus 로고
    • Specific recruitment of gammadelta regulatory T cells in human breast cancer
    • Ye J, Ma C, Wang F, Hsueh EC, Toth K, et al. (2013) Specific recruitment of gammadelta regulatory T cells in human breast cancer. Cancer Res.
    • (2013) Cancer Res
    • Ye, J.1    Ma, C.2    Wang, F.3    Hsueh, E.C.4    Toth, K.5
  • 15
    • 84886943825 scopus 로고    scopus 로고
    • HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
    • Schmidt HH, Ge Y, Hartmann FJ, Conrad H, Klug F, et al. (2013) HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients. Oncoimmunology 2: e24962.
    • (2013) Oncoimmunology , vol.2
    • Schmidt, H.H.1    Ge, Y.2    Hartmann, F.J.3    Conrad, H.4    Klug, F.5
  • 16
    • 84880757177 scopus 로고    scopus 로고
    • Deciphering and reversing tumor immune suppression
    • Motz GT, Coukos G (2013) Deciphering and reversing tumor immune suppression. Immunity 39: 61-73.
    • (2013) Immunity , vol.39 , pp. 61-73
    • Motz, G.T.1    Coukos, G.2
  • 18
    • 78650982038 scopus 로고    scopus 로고
    • Concurrent conditions and human listeriosis, England, 1999-2009
    • Mook P, O'Brien SJ, Gillespie IA (2011) Concurrent conditions and human listeriosis, England, 1999-2009. Emerg Infect Dis 17: 38-43.
    • (2011) Emerg Infect Dis , vol.17 , pp. 38-43
    • Mook, P.1    O'Brien, S.J.2    Gillespie, I.A.3
  • 19
    • 84878792082 scopus 로고    scopus 로고
    • Vital signs: Listeria illnesses, deaths, and outbreaks - United States, 2009-2011
    • (2013) Vital signs: Listeria illnesses, deaths, and outbreaks - United States, 2009-2011. MMWR Morb Mortal Wkly Rep 62: 448-452.
    • (2013) MMWR Morb Mortal Wkly Rep , vol.62 , pp. 448-452
  • 20
    • 33745146498 scopus 로고    scopus 로고
    • The epidemiology of sepsis in patients with malignancy
    • DOI 10.1378/chest.129.6.1432
    • Danai PA, Moss M, Mannino DM, Martin GS (2006) The epidemiology of sepsis in patients with malignancy. Chest 129: 1432-1440. (Pubitemid 43894970)
    • (2006) Chest , vol.129 , Issue.6 , pp. 1432-1440
    • Danai, P.A.1    Moss, M.2    Mannino, D.M.3    Martin, G.S.4
  • 21
    • 80051939064 scopus 로고    scopus 로고
    • Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality
    • Fox AC, Breed ER, Liang Z, Clark AT, Zee-Cheng BR, et al. (2011) Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality. J Immunol 187: 1950-1956.
    • (2011) J Immunol , vol.187 , pp. 1950-1956
    • Fox, A.C.1    Breed, E.R.2    Liang, Z.3    Clark, A.T.4    Zee-Cheng, B.R.5
  • 22
    • 77249138225 scopus 로고    scopus 로고
    • Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis
    • Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, et al. (2010) Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis. Crit Care Med 38: 886-893.
    • (2010) Crit Care Med , vol.38 , pp. 886-893
    • Fox, A.C.1    Robertson, C.M.2    Belt, B.3    Clark, A.T.4    Chang, K.C.5
  • 25
    • 79951828813 scopus 로고    scopus 로고
    • Limiting the Amount and Duration of Antigen Exposure during Priming Increases Memory T Cell Requirement for Costimulation during Recall
    • Floyd TL, Koehn BH, Kitchens WH, Robertson JM, Cheeseman JA, et al. (2011) Limiting the Amount and Duration of Antigen Exposure during Priming Increases Memory T Cell Requirement for Costimulation during Recall. The Journal of Immunology 186: 2033-2041.
    • (2011) The Journal of Immunology , vol.186 , pp. 2033-2041
    • Floyd, T.L.1    Koehn, B.H.2    Kitchens, W.H.3    Robertson, J.M.4    Cheeseman, J.A.5
  • 26
    • 18744430914 scopus 로고    scopus 로고
    • Compartmentalization of bacterial antigens: Differential effects on priming of CD8 T cells and protective immunity
    • DOI 10.1016/S0092-8674(00)80946-0
    • Shen H, Miller JF, Fan X, Kolwyck D, Ahmed R, et al. (1998) Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell 92: 535-545. (Pubitemid 28101116)
    • (1998) Cell , vol.92 , Issue.4 , pp. 535-545
    • Shen, H.1    Miller, J.F.2    Fan, X.3    Kolwyck, D.4    Ahmed, R.5    Harty, J.T.6
  • 27
    • 0028178784 scopus 로고
    • T cell receptor antagonist peptides induce positive selection
    • DOI 10.1016/0092-8674(94)90169-4
    • Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, et al. (1994) T cell receptor antagonist peptides induce positive selection. Cell 76: 17-27. (Pubitemid 24035278)
    • (1994) Cell , vol.76 , Issue.1 , pp. 17-27
    • Hogquist, K.A.1    Jameson, S.C.2    Heath, W.R.3    Howard, J.L.4    Bevan, M.J.5    Carbone, F.R.6
  • 28
    • 73449119607 scopus 로고    scopus 로고
    • CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages
    • van der Windt GJ, van 't Veer C, Florquin S, van der Poll T (2010) CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages. Infect Immun 78: 115-124.
    • (2010) Infect Immun , vol.78 , pp. 115-124
    • Van Der Windt, G.J.1    Van 'T Veer, C.2    Florquin, S.3    Van Der Poll, T.4
  • 29
    • 85027906707 scopus 로고    scopus 로고
    • Programmed death 1 and B and T lymphocyte attenuator immunoreceptors and their association with malignant T-lymphoproliferative disorders: Brief review
    • Karakatsanis S, Bertsias G, Roussou P, Boumpas D (2013) Programmed death 1 and B and T lymphocyte attenuator immunoreceptors and their association with malignant T-lymphoproliferative disorders: brief review. Hematol Oncol.
    • (2013) Hematol Oncol
    • Karakatsanis, S.1    Bertsias, G.2    Roussou, P.3    Boumpas, D.4
  • 30
    • 74949125667 scopus 로고    scopus 로고
    • BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination
    • Derre L, Rivals JP, Jandus C, Pastor S, Rimoldi D, et al. (2010) BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. J Clin Invest 120: 157-167.
    • (2010) J Clin Invest , vol.120 , pp. 157-167
    • Derre, L.1    Rivals, J.P.2    Jandus, C.3    Pastor, S.4    Rimoldi, D.5
  • 31
    • 74949088573 scopus 로고    scopus 로고
    • Putting the brakes on BTLA in T cell-mediated cancer immunotherapy
    • Paulos CM, June CH (2010) Putting the brakes on BTLA in T cell-mediated cancer immunotherapy. J Clin Invest 120: 76-80.
    • (2010) J Clin Invest , vol.120 , pp. 76-80
    • Paulos, C.M.1    June, C.H.2
  • 32
    • 84876478036 scopus 로고    scopus 로고
    • T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production
    • Riches JC, Davies JK, McClanahan F, Fatah R, Iqbal S, et al. (2013) T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production. Blood 121: 1612-1621.
    • (2013) Blood , vol.121 , pp. 1612-1621
    • Riches, J.C.1    Davies, J.K.2    McClanahan, F.3    Fatah, R.4    Iqbal, S.5
  • 33
    • 82655184651 scopus 로고    scopus 로고
    • The PDL1-PD1 axis converts human TH1 cells into regulatory T cells
    • Amarnath S, Mangus CW, Wang JC, Wei F, He A, et al. (2011) The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. Sci Transl Med 3: 111ra120.
    • (2011) Sci Transl Med , vol.3
    • Amarnath, S.1    Mangus, C.W.2    Wang, J.C.3    Wei, F.4    He, A.5
  • 34
    • 84883863501 scopus 로고    scopus 로고
    • Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells
    • Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, et al. (2013) Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells. Sci Transl Med 5: 200ra116.
    • (2013) Sci Transl Med , vol.5
    • Spranger, S.1    Spaapen, R.M.2    Zha, Y.3    Williams, J.4    Meng, Y.5
  • 35
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12: 252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 36
    • 84873372202 scopus 로고    scopus 로고
    • Advances in targeting cell surface signalling molecules for immune modulation
    • Yao S, Zhu Y, Chen L (2013) Advances in targeting cell surface signalling molecules for immune modulation. Nat Rev Drug Discov 12: 130-146.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 130-146
    • Yao, S.1    Zhu, Y.2    Chen, L.3
  • 37
    • 84876979617 scopus 로고    scopus 로고
    • Involvement of CD244 in regulating CD4+ T cell immunity in patients with active tuberculosis
    • Yang B, Wang X, Jiang J, Cheng X (2013) Involvement of CD244 in regulating CD4+ T cell immunity in patients with active tuberculosis. PLoS One 8: e63261.
    • (2013) PLoS One , vol.8
    • Yang, B.1    Wang, X.2    Jiang, J.3    Cheng, X.4
  • 38
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation
    • Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, et al. (2010) Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation. PLoS Pathog 6: e1000947.
    • (2010) PLoS Pathog , vol.6
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3    Timm, J.4    Kuntz, M.5
  • 39
    • 79958076040 scopus 로고    scopus 로고
    • Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells
    • Schlaphoff V, Lunemann S, Suneetha PV, Jaroszewicz J, Grabowski J, et al. (2011) Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells. PLoS Pathog 7: e1002045.
    • (2011) PLoS Pathog , vol.7
    • Schlaphoff, V.1    Lunemann, S.2    Suneetha, P.V.3    Jaroszewicz, J.4    Grabowski, J.5
  • 40
    • 84876783562 scopus 로고    scopus 로고
    • Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanoma
    • Goding SR, Wilson KA, Xie Y, Harris KM, Baxi A, et al. (2013) Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanoma. J Immunol 190: 4899-4909.
    • (2013) J Immunol , vol.190 , pp. 4899-4909
    • Goding, S.R.1    Wilson, K.A.2    Xie, Y.3    Harris, K.M.4    Baxi, A.5
  • 41
    • 34548027000 scopus 로고    scopus 로고
    • + T Cell Fates via the Graded Expression of T-bet Transcription Factor
    • DOI 10.1016/j.immuni.2007.07.010, PII S1074761307003718
    • Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, et al. (2007) Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295. (Pubitemid 47284924)
    • (2007) Immunity , vol.27 , Issue.2 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6    Gapin, L.7    Kaech, S.M.8
  • 42
    • 38449086421 scopus 로고    scopus 로고
    • Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation
    • Sarkar S, Teichgraber V, Kalia V, Polley A, Masopust D, et al. (2007) Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. J Immunol 179: 6704-6714.
    • (2007) J Immunol , vol.179 , pp. 6704-6714
    • Sarkar, S.1    Teichgraber, V.2    Kalia, V.3    Polley, A.4    Masopust, D.5
  • 43
    • 61549120751 scopus 로고    scopus 로고
    • Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation
    • Cui W, Joshi NS, Jiang A, Kaech SM (2009) Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation. Vaccine 27: 2177-2187.
    • (2009) Vaccine , vol.27 , pp. 2177-2187
    • Cui, W.1    Joshi, N.S.2    Jiang, A.3    Kaech, S.M.4
  • 44
    • 84864020108 scopus 로고    scopus 로고
    • Signal 3 cytokines as modulators of primary immune responses during infections: The interplay of type I IFN and IL-12 in CD8 T cell responses
    • Keppler SJ, Rosenits K, Koegl T, Vucikuja S, Aichele P (2012) Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses. PLoS One 7: e40865.
    • (2012) PLoS One , vol.7
    • Keppler, S.J.1    Rosenits, K.2    Koegl, T.3    Vucikuja, S.4    Aichele, P.5
  • 45
    • 44449145582 scopus 로고    scopus 로고
    • IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection
    • Wilson DC, Matthews S, Yap GS (2008) IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection. J Immunol 180: 5935-5945.
    • (2008) J Immunol , vol.180 , pp. 5935-5945
    • Wilson, D.C.1    Matthews, S.2    Yap, G.S.3
  • 46
    • 65549084772 scopus 로고    scopus 로고
    • PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
    • Huang X, Venet F, Wang YL, Lepape A, Yuan Z, et al. (2009) PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis. Proc Natl Acad Sci U S A 106: 6303-6308.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6303-6308
    • Huang, X.1    Venet, F.2    Wang, Y.L.3    Lepape, A.4    Yuan, Z.5
  • 47
    • 84865457276 scopus 로고    scopus 로고
    • BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction
    • Shubin NJ, Chung CS, Heffernan DS, Irwin LR, Monaghan SF, et al. (2012) BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction. J Leukoc Biol 92: 593-603.
    • (2012) J Leukoc Biol , vol.92 , pp. 593-603
    • Shubin, N.J.1    Chung, C.S.2    Heffernan, D.S.3    Irwin, L.R.4    Monaghan, S.F.5


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