Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells

Breast Cancer Research and Treatment

Volumn 151, Issue 1, 2015, Pages 57-73

  Teh, Jessica L F ^a   Shah, Raj ^a   La Cava, Stephanie ^a   Dolfi, Sonia C ^b   Mehta, Madhura S ^b   Kongara, Sameera ^b   Price, Sandy ^b   Ganesan, Shridar ^b   Reuhl, Kenneth R ^a   Hirshfield, Kim M ^b   Karantza, Vassiliki ^b   Chen, Suzie ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

Breast cancer; Cell transformation; Mammary epithelial cells; Metabotropic glutamate receptor 1; Oncogene

Indexed keywords

8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; GLUTAMIC ACID; METABOTROPIC RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; RILUZOLE; FUSED HETEROCYCLIC RINGS; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST EPITHELIUM CELL; CANCER INHIBITION; CARCINOGENESIS; CELL DEATH; CELL ISOLATION; CELL POLARITY; CONTROLLED STUDY; CYTOARCHITECTURE; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT TRANSFORMATION; MGLUR1 GENE; MOLECULAR CLONING; MORPHOGENESIS; MOUSE; NONHUMAN; ONCOGENE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; MCF 7 CELL LINE; PATHOLOGY; UDDER;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MAMMARY GLANDS, ANIMAL; MCF-7 CELLS; MICE; RECEPTORS, METABOTROPIC GLUTAMATE; RILUZOLE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84928535969     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-015-3365-8     Document Type: Article

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