Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells

Journal of Ethnopharmacology

Volumn 169, Issue , 2015, Pages 8-17

  Carre, Grégoire ^a   Ouedraogo, Maurice ^b   Magaud, Christophe ^a   Carreyre, Hélène ^a   Becq, Frédéric ^a   Bois, Patrick ^a   Supuran, Claudiu T ^c   Thibaudeau, Sébastien ^a   Vandebrouck, Clarisse ^a   Bescond, Jocelyn ^a  

^a UNIVERSITÉ DE POITIERS   (France)

^b UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Dodoneine; Hypertension; L type calcium current; Natural substance; Vasorelaxation

Indexed keywords

ACETAZOLAMIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE III; CARBONATE DEHYDRATASE XIII; CARBONATE DEHYDRATASE XIV; DODONEINE; ENZYME INHIBITOR; UNCLASSIFIED DRUG; VERAPAMIL; CARBONATE DEHYDRATASE INHIBITOR; PHENOL DERIVATIVE; PYRONE DERIVATIVE; VASODILATOR AGENT;

AGELANTHUS DODONEIFOLIUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CALCIUM CURRENT; CELL PH; CONTROLLED STUDY; ENZYME INHIBITION; EXCITATION CONTRACTION COUPLING; FLOW CYTOMETRY; GENE EXPRESSION; HYPERPOLARIZATION; HYPERTENSION; MALE; MEDICINAL PLANT; MEMBRANE STEADY POTENTIAL; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR RING; VASCULAR SMOOTH MUSCLE CELL; VASODILATATION; WHOLE CELL PATCH CLAMP; ANIMAL; AORTA; DRUG EFFECTS; MEMBRANE POTENTIAL; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

AGELANTHUS DODONEIFOLIUS; RATTUS;

ANIMALS; AORTA; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CARBONIC ANHYDRASE INHIBITORS; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; ORGAN CULTURE TECHNIQUES; PHENOLS; PYRONES; RATS; RATS, WISTAR; VASODILATION; VASODILATOR AGENTS;

EID: 84928496521     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.03.037     Document Type: Article

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