AFRICAN MISTLETOES (LORANTHACEAE); ETHNOPHARMACOLOGY, CHEMISTRY AND MEDICINAL VALUES: AN UPDATE

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 10, Issue 4, 2013, Pages 161-170

  Adesina, Simeon K ^a,b   Illoh, H C ^a   Johnny, Imoh I ^b   Jacobs, Imoh E ^b  

^a OBAFEMI AWOLOWO UNIVERSITY   (Nigeria)

^b UNIVERSITY OF UYO   (Nigeria)

Author keywords

Botany; Chemistry; Ethnopharmacology; Loranthaceae; Medicinal values; Mistletoes; Pharmacological Effects; Viscaceae

Indexed keywords

PLANT EXTRACT;

ANIMAL; BOTANY; CHEMISTRY; ETHNOPHARMACOLOGY; HUMAN; LORANTHACEAE; MEDICINAL VALUES; MISTLETOES; PHARMACOLOGICAL EFFECTS; PHYTOTHERAPY; REVIEW; VISCACEAE;

BOTANY; CHEMISTRY; ETHNOPHARMACOLOGY; LORANTHACEAE; MEDICINAL VALUES; MISTLETOES; PHARMACOLOGICAL EFFECTS; VISCACEAE;

ANIMALS; ETHNOPHARMACOLOGY; HUMANS; LORANTHACEAE; PHYTOTHERAPY; PLANT EXTRACTS;

EID: 84900729271     PISSN: None     EISSN: 25050044     Source Type: Journal    
DOI: 10.4314/ajtcam.v10i4.26     Document Type: Article

References (69)

1. Aboughe Angone, S., Bardor, M., Nguema-Ona, E., Rihouey, C., Ishii, T., Lerouge, P., Driouich, A. (2009). Structural characterization of cell wall polysaccharides from two plant species endemic to Central Africa, Fleurya aestuans and Phragmanthera capitata. Carbohydrate polymers 75(1); 104-109.
2. rd Edition, Edo State pgs; 103-111.7th Printing by Generation Press Ltd, Surulere, Lagos.
3. Adsersen, A. and Adsersen, H. (1997). Plants from Reunion Island with alleged antihypertensive and diuretic effects, an experimental and ethnobotanical evaluation. J. Ethnopharmacol 58; 189-206.
4. Akanji. M. A., Ayorinde, B. T., Yakubu, M. T., (2009). Anti-lipidaemic potentials of aqueous extract of Tapinanthus globiferus leaves in rats. RPMP Vol 25-Chemistry and Medicinal Value, Eds. V.K. Singh and J. N. Govil pg 1-9.
5. Akinmoladun, A. C., Obuotor, E. M.,Farombi, E. O., (2010). Evaluation of antioxidant and free radical scavenging capacities of some Nigerian Indigenous Medicinal Plants. Journal of Medicinal Food 13(2); 444-451.
6. Bannister, P., Graham, L., Strong, Inge A., (2002).Differential accumulation of nutrient elements in some new mistletoes and their hosts. Functional Plant Biology 29 (11); 1309-1318.
7. Begho, E. R.,Omokhafe, K. O., Omo-Ikerodah, E. E. and Akpaja, E.O. (2007). Some observations on the fruit set and incidence of Mistletoes on rubber trees in Nigeria. Am-Eurasian J. Sustain. Agric. 1(1); 13-18.
8. Bright, E. O. and Okusanya, B. A.,(1998). Infestation of economic plants in Badeggi by Tapinanthus dodoneifolius (DC) Danser and Tapinanthus globiferus (A. Rich) Van Tiegh. Nigerian J. of Weed Science 11; 51-56.
9. Burkill, H.M., (1985), The useful Plants of West Tropical Africa. Royal Botanical Gardens, Kew. Vol.3 (families J-L) pgs; 548-560.
10. Cebovic, T., Spasic, S., Popovic, M. (2008). Cytotoxic effects of the Viscum album L. extract on Ehrlich tumour cells in vivo. Phytother, Res. 22(8); 1097.
11. Cook, J. A., Van der Jagt, D. J., Dasgupta, A., Mounkaila, G., Glew, R.S., Blackwell, W., Glew, R. H., (1998). Use of the Trolox assay to estimate the antioxidant content of seventeen edible wild plants of Niger. Life Sci. 63(2); 105-110.
12. Deeni, Y. Y., Sadiq, N. M., (2002). Antimicrobial properties and phytochemical constituents of the leaves of African mistletoe (Tapinanthus dodoneifolius (DC) Danser (Loranthaceae): an ethnomedicinal plant of Hausaland, Northern Nigeria. J. Ethnopharmacol. 83(3); 235-240.
13. Deliorman, D., Calis, I., Ergun, F. (2000) Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp album, J. Ethnopharmacol. 72: 323-329.
14. Devehat, F. L-L., Tomasi, S., Fontanel, D., Boustie, J. (2002). Flavonoids from Scurrula ferruginea Danser (Loranthaceae). Z. Naturforsch 57c, 1092-1095.
15. Dibong, S. D., Engone, O.N.L., Din, N., Priso, R. J., Taffouo, V. O. D., Fankem, H., Salle, G., Missoup, A. D., Boussim, I. J. and Amougou, A. (2009). An assessment on the uses of Loranthaceae in ethnopharmacology in Cameroon; A case study made in Logbessou, North of Douala. J Med Plants Res 3(8); 592-595.
16. Dibong, S. D., Taffouo, V. D., Ndiang, Z., Ngotta, B., Mony, R., Engone Obiang, N. L., Din, N., Priso, J. R., Issaka, B. J. and Amougou, A. (2010). The study of sodium and potassium distribution in five host species of Phragmanthera capitata (Sprengel) S. Balle in the littoral region of Cameroon. J. Appl. Biosci 30: 1839-1844.
17. Edem, D.O., (2009). Effect of aqueous extracts of leaves of Globimetula cupulata (DC) Van Tieghem in Normoglycemic Rats. The internet J. Alt. Med. 8(1); 1-6.
18. Ekhaise, F. O., Kayode, A. M., Sylvester, U., (2011), Evaluation of the methanolic extract of mistletoe (Tapinanthus bangwensis) leaves grown on orange trees for the phytochemical properties and its physiological effects on streptozotocin-induced diabetes mellitus in laboratory animals. Global J. Pure and Applied Sci. 17(3);
19. Erukainure, O. L., Abovwe, J. A., Adefegha, A. S., Egwuche, R. U., Fafunso, M. A., (2011). Antilipemic and hypocholesteremic activities of Globimetula braunii in rats. Exp. Toxicol. Pathol. 63(7-8); 657-661.
20. Fasanu, P. O., Oyedapo, O. O., (2008). Phragmanthin-peptide from fresh leaves of African mistletoe (Phragmanthera incana): purification and metabolic activities. In; Recent Progress in Medicinal Plants 19: Phytopharmacology and Therapeutic Values 1(J. N. Govil, V. K. Singh and R. Bhardwaj Eds.) 28; pg 39-47.
21. Fred-Jaiyesimi, A., Onabanjo, T., Ademuyiwa, O. (2008). Phytochemical and laxative studies of Globimetula braunii (Engle) van Tiegh growing on Cola acuminata (Schott & Endl).
22. Fukunaga, T., Nishiya, K., Kajikawa, I., Takeya, K., Itokawa, H., (1989). Studies on the constituents of Japanese mistletoes from different host trees and their antimicrobial and hypotensive properties. Chem Pharm. Bull. (Tokyo) 37(6); 1543-1546.
23. Gill, L. S., and Onyibe, H. I., (1990). Mistletoes on rubber trees in Nigeria. Haustorium 23; 1-2.
24. Gray, A. M., and Flatt, P.R., (1999). Insulin-secreting activity of the traditional anti-diabetic plant V. album (mistletoe). J. Endocrinol. 160; 409-414.
25. th Asian Pacific Weed Science Society Conference, Indonesia pp. 58-66.
26. Jadhav, N., Patil, C. R., Chaudhari, K. B., Wagh, J. P., Surana, S. J., and Jadhav, R. B., (2010). Diuretic and natriuretic activity of two mistletoes species in rats. Phcog Research 2(1); 50-57.
27. nd March, 2007. (Burgt, X. van der; Maesen, J. van der; Onana, J. M., Editors). Pp 229-235.
28. Karunaichamy, K., Arp, K. Paliwal, A. (1999). Biomass and nutrient dynamics of mistletoe (Dendrophtoe falcata) and neem (Azadirachta indica) seedlings. Current Sci. 76(6); 840-843.
29. Ken’ichi, M., Kazuhiro, N., Norimasa, N.,Dawa, D., Laximi, T., Atsushi, W., Fumi, M., Toshiro, B., Gaku, M. (2006). Report of investigation for Wild Edible Plants and their Traditional Knowledge in Bhutan. J. Faculty Agric. Shinshu University 42 (1-2); 37-47.
30. Kienle, G. S., Glockmann, A., Schink, M., Kiene, H. (2009). V. album L. extracts in breast and gynaecological cancers; a systematic review of clinical and preclinical research. J.Exp. Clin. Cancer res. 28; 79.
31. Kienle, G. S., Kiene, H., (2007). Complementary cancer therapy; a systematic review of prospective clinical trials on anthroposophic Mistletoe extracts. Eur. J. Med. Res. 12; 103-119.
32. Kienle, G. S., Kiene, H., (2010). Review article: Influence of V. album L. (European mistletoe) extracts on quality of life in cancer patients; a systematic review of controlled clinical studies. Integr. Cancer Ther. 9(2); 142-157.
33. Kim,Y-K., Kim, Y-S., Choi, S. U., Ryu, S-Y. (2004). Isolation of flavonoid rhamnosides from Loranthus tanakae and cytotoxic effect of them on Human Tumor Cell Lines. Arch. Pharm. Res. 27(1); 44-47.
34. Le,O., Zam, N., (2008). Oxytocic properties of the aqueous extract of Globimetula braunii (Loranthaceae). Pak. J. Pharm. Sci. 21(4); 356-360.
35. Lin, J-H., Chlou, Y-N., Lin, Y-L., (2002). Phenolic glycosides from V. angulatum J. Nat. Prod. 65(5); 638-640.
36. Lutomski, J. (1986). Evaluation of the hypotensional activity of some mistletoe (V. album L.) drugs. Int. Meeting on V. album, Heidelberg.
37. Mahfouz, M. M., Ghaleb, H. A., Zawawy, A., scheffer, a., (1998). Significant tumour reduction, improvement of pain and quality of life and normalization of sleeping patterns of cancer patients treated with a high dose of mistletoe. Ann Oncol. 9(2); 129-138.
38. Mallavadhani, U. V., Narasimhan, K., Venkata, A., Sudhakar, S., Mahapatra, A., Li, W., Breemen, R. B. V., (2006). Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian Ayurvedic Plant Dendrophthoe falcata and their estrogen receptor binding activity. Chem. Pharm. Bull. 54 (5); 740-744.
39. Margaret E. Loeper, MS., (1999). Mistletoe (Viscum album L.) Longwood Herbal Task Force (http://www.mep.edu/herbal/default.htm).
40. Matthes, H., Schad, F., Buchward. D., Schenk, G., (2005). Endoscopic ultrasound-guided fine needle injection of V. album L. (mistletoe; Helixor M) in the therapy of primary inoperable pancreas cancer; a pilot study. Gastroenterol. 128 (4 Suppl.2); 433, T 988.
41. Mengs, U., Gothel, D., Leng-Peschlow, E. (2002). Mistletoe extracts standardized to mistletoe lectins in oncology. Review on current status of preclinical research. Anticancer Res. 22; 1399-1405.
42. Ndukwe, I. G., Amupitan, J. O., Ashonibare, O. E., (2001). Phytochemical analysis and antimicrobial activity screening of the crude extracts from the aerial parts of Tapinanthus globiferus. Journal or book name, Nig. J. Chem. Res.6: 43-46.
43. Noumi, E., Eloumou, M. E. R., (2011). Syphilis ailment; Prevalence and herbal remedies in Ebolowa subdivision (South region, Cameroon). Int. J. Pharm. Biomed. Sci. 2(1); 20-28.
44. Obata, Y. (1941). The components of V.album III. The unsaponifiable matter of the leaves, the so-called α-viscol and γ-viscol. J. Agric. Chem. Soc. (Japan) 17; 784-786.
45. Ojewole, J.A.O., Adewole, S. O., (2007). Hypoglycemic and hypotensive effects of Globimetula cupulata (DC) Van Tieghem (Loranthaceae) aqueous leaf extract. Cardiovasc. J. S. Afr. 18(1); 9-15.
46. Okpako, L. C., Ajaiyeoba, E., O., (2004). In vitro and in vivo antimalarial studies of Striga hermonthica and Tapinanthus sessilifolius extracts African J. of Medicine and Medical Sciences. 33(1); 73-75.
47. Okpuzor, J., Ogbunugafor, H., Kareem, G.K., (2009). Antioxidative properties of ethyl acetate fraction of Globimetula braunii in normal albino rats. J. Biol. Sci. 9(5); 470.
48. Okpuzor, J. Ogbunugafor, H. A., Kareem, G. K.,(2009). Hepatic and hematologic effects of fractions of Globimetula braunii in normal albino rats. Excli; Journal 8; 182-189.
49. Orhan, D. D., Asian, M., Sendogolu, N., (2005). Evaluation of the hypoglycaemic effect and antioxidant activity of three V. album subspecies (European mistletoe) in streptozotocin-diabetic rats. J. Ethnopharmacol. 98; 95-102.
50. Overfield, D., Riches, C., Samoah, A.M., Sarkodie, O., Baah, F., (1998). A farming system analysis of the mistletoe problem in Ghanian Cocoa. Cocoa Grower’s Bulletin 51; 42-50.
51. Parker, C., Riches, C. R., (1993). Parasitic weeds of the World; Biology and Control, CAB International, Wallingford pg. 332.
52. Patrick-Iwuanyanwu, K. C., Onyeike, E. N., Wegwu, M. O., (2010). Anti-inflammatory effect of crude methanolic extract and fractions of African mistletoe Tapinanthus bangwensis (Engl. & K. Krause) on wistar albino rats. Der Pharmacia Lettre 2(6); 76-83.
53. Patrick-Iwuanyanwu, K. C., Onyeike, E. N., Wegwu, M. O., (2010).Hepatoprotective effects of methanolic extract and fractions of African mistletoe Tapinanthus bangwensis (Engl. & K. Krause) from Nigeria. Excli Journal 9; 187-194.
54. Pattanayak, S. P., Sunita, P.,(2008). Wound healing, anti-microbial and antioxidant potential of Dendrophthoe falcata (L. f) Ettingsh. J. of Ethnopharmcol. 120; 241-247.
55. Pattanayak, S. P., Mazumder, P. M., Sunita, P. (2008). Dendrophtoe falcate (L. f); a concensus review. Phcog Reviews 8: 359-368.
56. Pattanayak, S. P., Mazumder, P. M., Sunita, P. (2012). Total Phenolic Content, Flavonoid content and in vitro antioxidant activities of D. falcate (L. f) Ettingh. Res. J. Med. Plant 6(2): 136-148.
57. Polhill, R., Wiens, D. (1998). Mistletoe of Africa. The Royal Botanic Garden, Kew, U. K. pg 370.
58. Samuelsson, G., Pettersson, B. M., (1971). The amino acid sequence of viscotoxin B from the European mistletoe (Viscum album L., Loranthaceae). Eur. J. Biochem. 21 (1); 86-89.
59. Schaller, G., Urech, K., Grazi, G., Giannattasio, M. (1998). Viscotoxin composition of the three European subspecies of V. album. Planta Med. 64(7); 677-678.
60. Sher, H., Alyemeni. M. N., (2011). Pharmaceutically important plants used in traditional system of Arab medicine for the treatment of livestock ailments in the kingdom of Saudi Arabia. African Journal of Biotechnology 10(45); 9153-9159.
61. Sridhar, T. S., Rao, V. R. (1978), Dendrophthoe falcata, a menace to fruit orchards. Current Sci. 38; 908.
62. Swanson-Flatt, S. K., Day, C., Bailey, C. J., Flatt, P. R., (1989). Evaluation of traditional plant treatments for diabetes; Studies in streptozotocin diabetic mice. Acta Diabetologica Latina 26; 51-55.
63. Talha, J., Priyanka, M. Akanksha,A. (2011). Hypertension and herbal plants. International Research J. of Pharm. (IRJP), 2(8); 26-30.
64. Wang, Y., Deng, M., Zhang, S-Y., Zhou, Z-K., Tian, W-X., (2008). Parasitic loranthus from Loranthaceae rather than Viscaceae potently inhibits fatty acid synthase and reduces body weight in mice. J. Ethnopharmacol. 118(3); 473-478.
65. Weston, K. A., Chapman, H. M., Kelly, D., Moltchanova, E. V., (2012). Dependence on Sunbird pollination for fruit set in three West African montane Mistletoe species. Journal of Tropical Ecology, 28; 205-213.
66. Urech, K., Scher, J. M., Hostanska, K., (2005). Apoptosis inducing activity of viscin, a lipophilic extract from V. album L. J. Pharm. Pharmacol. 57; 101-109.
67. Yineger, H., Yewhalaw, D., (2007). Traditional medicinal plant knowledge and use by local healers in Sekoru District, Jimma Zone, Southwestern Ethiopia. Journal of Ethnobiology and Ethnomedicine 3; 24.
68. Zee-Cheng, R., (1997). Anticancer research on Loranthaceae plants. Drugs Future. 22; 519-530.
69. th Annual Conference of the Ethiopian Weed Science Committee, Rezene Fesehale (IAR,(Ethiopia): EWSC, 1993. Pg.41-42.