The hypotensive agent dodoneine inhibits L-type Ca2+ current with negative inotropic effect on rat heart

European Journal of Pharmacology

Volumn 728, Issue 1, 2014, Pages 119-127

  Carré, Grégoire ^a   Carreyre, Hélène ^a   Ouedraogo, Maurice ^b   Becq, Frédéric ^a   Bois, Patrick ^a   Thibaudeau, Sébastien ^a   Vandebrouck, Clarisse ^a   Bescond, Jocelyn ^a  

^a UNIVERSITÉ DE POITIERS   (France)

^b UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

Author keywords

Calcium channel blocking drugs; Dodoneine; Hypertension; Isolated rat heart; L type calcium current; Natural substance

Indexed keywords

ANTIHYPERTENSIVE AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; DILTIAZEM; DODONEINE; NIFEDIPINE; PYRAN DERIVATIVE; UNCLASSIFIED DRUG; PHENOL DERIVATIVE; PYRONE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM SIGNALING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; EX VIVO STUDY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART RATE; IC 50; IN VITRO STUDY; INOTROPISM; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; AFRICAN MEDICINE; ANIMAL; CHEMISTRY; DRUG EFFECTS; HEART CONTRACTION; HEART VENTRICLE; HEART VENTRICLE PRESSURE; ISOLATION AND PURIFICATION; LORANTHACEAE; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE; WISTAR RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNELS, L-TYPE; HEART VENTRICLES; IN VITRO TECHNIQUES; LORANTHACEAE; MALE; MEDICINE, AFRICAN TRADITIONAL; MEMBRANE POTENTIALS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHENOLS; PYRONES; RATS; RATS, WISTAR; VENTRICULAR PRESSURE;

EID: 84896702568     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.01.059     Document Type: Article

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