Inhibition of carbonic anhydrase accounts for the direct vascular effects of hydrochlorothiazide

Hypertension

Volumn 33, Issue 4, 1999, Pages 1043-1048

  Pickkers, Peter ^a   Garcha, Robinder S ^b   Schachter, Michael ^b   Smits, Paul ^a   Hughes, Alun D ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Carbonic anhydrase inhibition; Hydrochlorothiazide; Muscle, smooth, vascular; PH(i); Potassium channels

Indexed keywords

ACETAZOLAMIDE; BENDROFLUMETHIAZIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; CHARYBDOTOXIN; HYDROCHLOROTHIAZIDE; NORADRENALIN; POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CELL PH; CHANNEL GATING; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GUINEA PIG; MALE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL; VASCULAR SMOOTH MUSCLE; VASODILATATION;

EID: 0032916495     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.33.4.1043     Document Type: Article

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