Stabilizing rescued surface-localized Δf508 CFTR by potentiation of its interaction with Na+/H+ exchanger regulatory factor 1

Biochemistry

Volumn 53, Issue 25, 2014, Pages 4169-4179

  Arora, Kavisha ^a   Moon, Changsuk ^a   Zhang, Weiqiang ^b,c   Yarlagadda, Sunitha ^a   Penmatsa, Himabindu ^b   Ren, Aixia ^b   Sinha, Chandrima ^a,b   Naren, Anjaparavanda P ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b Department of Physiology ^*  (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; PROTEINS; SODIUM;

ANION CHANNELS; BINDING AFFINITIES; CHANNEL PROTEINS; CYSTIC FIBROSIS; FUNCTIONAL EFFICIENCY; GENETIC DISEASE; PROTEIN-PROTEIN INTERACTIONS; REGULATORY FACTORS;

CELL MEMBRANES;

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; LUMACAFTOR; MUTANT PROTEIN; PHENYLALANINE; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR 1; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; MACROMOLECULE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; WILD TYPE;

AMINOPYRIDINES; ANIMALS; BENZODIOXOLES; CELL LINE; CELL MEMBRANE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MALE; MICE, INBRED C57BL; MUTATION; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTEIN STABILITY; SODIUM-HYDROGEN ANTIPORTER;

EID: 84903747898     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401263h     Document Type: Article

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