Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt

Journal of Immunology

Volumn 194, Issue 9, 2015, Pages 4094-4097

  Yang, Jing ^a   Xu, Peng ^b   Han, Lei ^c   Guo, Zhixiang ^b   Wang, Xiuwen ^c   Chen, Zuojia ^a   Nie, Jia ^a   Yin, Shuying ^a   Piccioni, Miranda ^a   Tsun, Andy ^a   Lv, Ling ^a,c   Ge, Shenglin ^b   Li, Bin ^a,d  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; DEUBIQUITINASE; DEUBIQUITINASE 4; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 17; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RETINOID RELATED ORPHAN RECEPTOR GAMMA T; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; RORC PROTEIN, HUMAN; UBIQUITIN THIOLESTERASE; USP4 PROTEIN, HUMAN;

ARTICLE; CATALYSIS; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE FUNCTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; TH17 CELL; UBIQUITINATION; CHEMISTRY; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY; RHEUMATIC HEART DISEASE;

CELL DIFFERENTIATION; HUMANS; INFLAMMATION; INTERLEUKIN-17; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; RHEUMATIC HEART DISEASE; RNA, MESSENGER; TH17 CELLS; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84928489333     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401451     Document Type: Article

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