Silencing IFN-γ binding/signaling in astrocytes versus microglia leads to opposite effects on central nervous system autoimmunity

Journal of Immunology

Volumn 194, Issue 9, 2015, Pages 4251-4264

  Ding, Xiaoli ^a,b   Yan, Yaping ^a,b   Li, Xing ^a   Li, Ke ^a   Ciric, Bogoljub ^a   Yang, Jingxian ^a,c   Zhang, Yuan ^a   Wu, Shuai ^a   Xu, Hui ^a   Chen, Wanjun ^d   Lovett Racke, Amy E ^e   Zhang, Guang Xian ^a   Rostami, Abdolmohamad ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b SHAANXI NORMAL UNIVERSITY   (China)

^c LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL2 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GAMMA INTERFERON RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; CHEMOKINE; INTERFERON RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL EXPANSION; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; GENE SILENCING; INFLAMMATORY CELL; MACROPHAGE; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; ANIMAL; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; ASTROCYTES; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; CHEMOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION; GENE SILENCING; INTERFERON-GAMMA; MICE; MICE, TRANSGENIC; MICROGLIA; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; TH1 CELLS; TH17 CELLS;

EID: 84928473638     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1303321     Document Type: Article

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