-
1
-
-
84876668625
-
Emerging roles of astrocytes in neural circuit development
-
Clarke, L.E., Barres, B.A. Emerging roles of astrocytes in neural circuit development. Nat. Rev. Neurosci. 14, 311-321 (2013).
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 311-321
-
-
Clarke, L.E.1
Barres, B.A.2
-
2
-
-
57349185900
-
Astroglial metabolic networks sustain hippocampal synaptic transmission
-
Rouach, N., Koulakoff, A., Abudara, V., Willecke, K., Giaume, C. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 322, 1551-1555 (2008).
-
(2008)
Science
, vol.322
, pp. 1551-1555
-
-
Rouach, N.1
Koulakoff, A.2
Abudara, V.3
Willecke, K.4
Giaume, C.5
-
3
-
-
33644519960
-
Astrocyte dysfunction in neurological disorders: A molecular perspective
-
Seifert, G., Schilling, K., Steinhauser, C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat. Rev. Neurosci. 7, 194-206 (2006).
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 194-206
-
-
Seifert, G.1
Schilling, K.2
Steinhauser, C.3
-
4
-
-
84864021984
-
Regional astrocyte allocation regulates CNS synaptogenesis and repair
-
Tsai, H.H. et al. Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science 337, 358-362 (2012).
-
(2012)
Science
, vol.337
, pp. 358-362
-
-
Tsai, H.H.1
-
5
-
-
0033152442
-
Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice
-
Bush, T.G. et al. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 23, 297-308 (1999).
-
(1999)
Neuron
, vol.23
, pp. 297-308
-
-
Bush, T.G.1
-
6
-
-
33749508895
-
Essential protective roles of reactive astrocytes in traumatic brain injury
-
Myer, D.J., Gurkoff, G.G., Lee, S.M., Hovda, D.A., Sofroniew, M.V. Essential protective roles of reactive astrocytes in traumatic brain injury. Brain 129, 2761-2772 (2006).
-
(2006)
Brain
, vol.129
, pp. 2761-2772
-
-
Myer, D.J.1
Gurkoff, G.G.2
Lee, S.M.3
Hovda, D.A.4
Sofroniew, M.V.5
-
7
-
-
78349263043
-
Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease
-
Toft-Hansen, H., Fuchtbauer, L., Owens, T. Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease. Glia 59, 166-176 (2011).
-
(2011)
Glia
, vol.59
, pp. 166-176
-
-
Toft-Hansen, H.1
Fuchtbauer, L.2
Owens, T.3
-
8
-
-
70349103383
-
Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS
-
Voskuhl, R.R. et al. Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J. Neurosci. 29, 11511-11522 (2009).
-
(2009)
J. Neurosci.
, vol.29
, pp. 11511-11522
-
-
Voskuhl, R.R.1
-
9
-
-
84862736732
-
The innate immune system in demyelinating disease
-
Mayo, L., Quintana, F.J., Weiner, H.L. The innate immune system in demyelinating disease. Immunol. Rev. 248, 170-187 (2012).
-
(2012)
Immunol. Rev.
, vol.248
, pp. 170-187
-
-
Mayo, L.1
Quintana, F.J.2
Weiner, H.L.3
-
11
-
-
65249142200
-
The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease?
-
Weiner, H.L. The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease? Ann. Neurol. 65, 239-248 (2009).
-
(2009)
Ann Neurol
, vol.65
, pp. 239-248
-
-
Weiner, H.L.1
-
12
-
-
84855375911
-
IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes
-
Joseph, J., Bittner, S., Kaiser, F.M., Wiendl, H., Kissler, S. IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes. J. Immunol. 188, 216-221 (2012).
-
(2012)
J. Immunol.
, vol.188
, pp. 216-221
-
-
Joseph, J.1
Bittner, S.2
Kaiser, F.M.3
Wiendl, H.4
Kissler, S.5
-
13
-
-
41849124231
-
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis
-
Basso, A.S. et al. Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. J. Clin. Invest. 118, 1532-1543 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1532-1543
-
-
Basso, A.S.1
-
14
-
-
69049084375
-
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
-
Farez, M.F. et al. Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat. Immunol. 10, 958-964 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 958-964
-
-
Farez, M.F.1
-
15
-
-
80051869587
-
Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease
-
Cao, W. et al. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity 35, 273-284 (2011).
-
(2011)
Immunity
, vol.35
, pp. 273-284
-
-
Cao, W.1
-
16
-
-
84979726329
-
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
-
Pluchino, S. et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 422, 688-694 (2003).
-
(2003)
Nature
, vol.422
, pp. 688-694
-
-
Pluchino, S.1
-
17
-
-
84863752786
-
Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models
-
Chatterjee, S., Alsaeedi, N. Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models. Adv. Exp. Med. Biol. 749, 153-169 (2012).
-
(2012)
Adv. Exp. Med. Biol.
, vol.749
, pp. 153-169
-
-
Chatterjee, S.1
Alsaeedi, N.2
-
18
-
-
3042841602
-
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: Implications for neuroinflammatory diseases
-
Pannu, R., Won, J.S., Khan, M., Singh, A.K., Singh, I. A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases. J. Neurosci. 24, 5942-5954 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 5942-5954
-
-
Pannu, R.1
Won, J.S.2
Khan, M.3
Singh, A.K.4
Singh, I.5
-
19
-
-
80052246111
-
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
-
Ajami, B., Bennett, J.L., Krieger, C., McNagny, K.M., Rossi, F.M. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat. Neurosci. 14, 1142-1149 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1142-1149
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
McNagny, K.M.4
Rossi, F.M.5
-
20
-
-
0034596949
-
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
-
Izikson, L., Klein, R.S., Charo, I.F., Weiner, H.L., Luster, A.D. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J. Exp. Med. 192, 1075-1080 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1075-1080
-
-
Izikson, L.1
Klein, R.S.2
Charo, I.F.3
Weiner, H.L.4
Luster, A.D.5
-
21
-
-
71549167047
-
CCR26Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
-
Mildner, A. et al. CCR26Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain 132, 2487-2500 (2009).
-
(2009)
Brain
, vol.132
, pp. 2487-2500
-
-
Mildner, A.1
-
22
-
-
55049091909
-
Distinct stages of myelination regulated by ?-secretase and astrocytes in a rapidly myelinating CNS coculture system
-
Watkins, T.A., Emery, B., Mulinyawe, S., Barres, B.A. Distinct stages of myelination regulated by ?-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron 60, 555-569 (2008).
-
(2008)
Neuron
, vol.60
, pp. 555-569
-
-
Watkins, T.A.1
Emery, B.2
Mulinyawe, S.3
Barres, B.A.4
-
23
-
-
77956520108
-
4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development
-
Nishie, T. ?4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development. Glycobiology 20, 1311-1322 (2010).
-
(2010)
Glycobiology
, vol.20
, pp. 1311-1322
-
-
Nishie, T.1
-
24
-
-
84887877953
-
4GalT6 is involved in the synthesis of lactosylceramide with less intensity than 4GalT5
-
Tokuda, N. et al. ?4GalT6 is involved in the synthesis of lactosylceramide with less intensity than ?4GalT5. Glycobiology 23, 1175-1183 (2013).
-
(2013)
Glycobiology
, vol.23
, pp. 1175-1183
-
-
Tokuda, N.1
-
25
-
-
84863463743
-
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
-
Yan, Y. et al. CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes. Mol. Ther. 20, 1338-1348 (2012).
-
(2012)
Mol. Ther.
, vol.20
, pp. 1338-1348
-
-
Yan, Y.1
-
26
-
-
81455150212
-
Lactosylceramide mediates the expression of adhesion molecules in TNF-? and IFN?-stimulated primary cultured astrocytes
-
Lee, J.K. et al. Lactosylceramide mediates the expression of adhesion molecules in TNF-? and IFN?-stimulated primary cultured astrocytes. Korean J. Physiol. Pharmacol. 15, 251-258 (2011).
-
(2011)
Korean J. Physiol. Pharmacol.
, vol.15
, pp. 251-258
-
-
Lee, J.K.1
-
27
-
-
0035911254
-
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
-
Huang, D.R., Wang, J., Kivisakk, P., Rollins, B.J., Ransohoff, R.M. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J. Exp. Med. 193, 713-726 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 713-726
-
-
Huang, D.R.1
Wang, J.2
Kivisakk, P.3
Rollins, B.J.4
Ransohoff, R.M.5
-
28
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner, F.L. et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat. Med. 11, 146-152 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
-
29
-
-
79959379095
-
Repertoire of microglial and macrophage responses after spinal cord injury
-
David, S., Kroner, A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat. Rev. Neurosci. 12, 388-399 (2011).
-
(2011)
Nat. Rev. Neurosci.
, vol.12
, pp. 388-399
-
-
David, S.1
Kroner, A.2
-
30
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence, T., Natoli, G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 11, 750-761 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
31
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
Murray, P.J., Wynn, T.A. Protective and pathogenic functions of macrophage subsets. Nat. Rev. Immunol. 11, 723-737 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
32
-
-
33846018916
-
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
-
Ponomarev, E.D. et al. GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J. Immunol. 178, 39-48 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 39-48
-
-
Ponomarev, E.D.1
-
33
-
-
2342523261
-
Lactosylceramide recruits PKC?/? and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells
-
Gong, N., Wei, H., Chowdhury, S.H., Chatterjee, S. Lactosylceramide recruits PKC?/? and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells. Proc. Natl. Acad. Sci. USA 101, 6490-6495 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6490-6495
-
-
Gong, N.1
Wei, H.2
Chowdhury, S.H.3
Chatterjee, S.4
-
34
-
-
84881412497
-
Lactosylceramide interacts with and activates cytosolic phospholipase A2?
-
Nakamura, H. et al. Lactosylceramide interacts with and activates cytosolic phospholipase A2?. J. Biol. Chem. 288, 23264-23272 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 23264-23272
-
-
Nakamura, H.1
-
35
-
-
84862129146
-
Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation
-
Ho, P.P. et al. Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation. Sci. Transl. Med. 4, 137-173 (2012).
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 137-173
-
-
Ho, P.P.1
-
36
-
-
1842682026
-
Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide
-
Jahng, A. et al. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 199, 947-957 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 947-957
-
-
Jahng, A.1
-
37
-
-
30044434622
-
Lipid microarrays identify key mediators of autoimmune brain inflammation
-
Kanter, J.L. et al. Lipid microarrays identify key mediators of autoimmune brain inflammation. Nat. Med. 12, 138-143 (2006).
-
(2006)
Nat. Med.
, vol.12
, pp. 138-143
-
-
Kanter, J.L.1
-
38
-
-
57749094962
-
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis
-
Quintana, F.J. et al. Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc. Natl. Acad. Sci. USA 105, 18889-18894 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18889-18894
-
-
Quintana, F.J.1
-
39
-
-
84862625677
-
Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis
-
Quintana, F.J., Yeste, A., Weiner, H.L., Covacu, R. Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis. J. Neuroimmunol. 248, 53-57 (2012).
-
(2012)
J. Neuroimmunol.
, vol.248
, pp. 53-57
-
-
Quintana, F.J.1
Yeste, A.2
Weiner, H.L.3
Covacu, R.4
-
40
-
-
34250357688
-
Resolvin E1 and protectin D1 activate inflammation-resolution programmes
-
Schwab, J.M., Chiang, N., Arita, M., Serhan, C.N. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447, 869-874 (2007).
-
(2007)
Nature
, vol.447
, pp. 869-874
-
-
Schwab, J.M.1
Chiang, N.2
Arita, M.3
Serhan, C.N.4
-
41
-
-
0035132767
-
GFAP promoter-controlled EGFP-expressing transgenic mice: A tool to visualize astrocytes and astrogliosis in living brain tissue
-
Nolte, C. et al. GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33, 72-86 (2001).
-
(2001)
Glia
, vol.33
, pp. 72-86
-
-
Nolte, C.1
-
42
-
-
34248673126
-
Isolation of murine microglial cells for RNA analysis or flow cytometry
-
Cardona, A.E., Huang, D., Sasse, M.E., Ransohoff, R.M. Isolation of murine microglial cells for RNA analysis or flow cytometry. Nat. Protoc. 1, 1947-1951 (2006).
-
(2006)
Nat. Protoc.
, vol.1
, pp. 1947-1951
-
-
Cardona, A.E.1
Huang, D.2
Sasse, M.E.3
Ransohoff, R.M.4
-
43
-
-
38149129457
-
A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
-
Cahoy, J.D. et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 28, 264-278 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 264-278
-
-
Cahoy, J.D.1
-
44
-
-
80053233055
-
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
-
Prinz, M., Priller, J., Sisodia, S.S., Ransohoff, R.M. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat. Neurosci. 14, 1227-1235 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1227-1235
-
-
Prinz, M.1
Priller, J.2
Sisodia, S.S.3
Ransohoff, R.M.4
-
45
-
-
84860322835
-
Genomic analysis of reactive astrogliosis
-
Zamanian, J.L. et al. Genomic analysis of reactive astrogliosis. J. Neurosci. 32, 6391-6410 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 6391-6410
-
-
Zamanian, J.L.1
-
46
-
-
76649122816
-
Expander: From expression microarrays to networks and functions
-
Ulitsky, I. et al. Expander: from expression microarrays to networks and functions. Nat. Protoc. 5, 303-322 (2010).
-
(2010)
Nat. Protoc.
, vol.5
, pp. 303-322
-
-
Ulitsky, I.1
-
47
-
-
0344013138
-
High-yield isolation of murine microglia by mild trypsinization
-
Saura, J., Tusell, J.M., Serratosa, J. High-yield isolation of murine microglia by mild trypsinization. Glia 44, 183-189 (2003).
-
(2003)
Glia
, vol.44
, pp. 183-189
-
-
Saura, J.1
Tusell, J.M.2
Serratosa, J.3
-
48
-
-
84887057618
-
IFN-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair
-
Kunis, G. et al. IFN-?-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair. Brain 136, 3427-3440 (2013).
-
(2013)
Brain
, vol.136
, pp. 3427-3440
-
-
Kunis, G.1
-
49
-
-
77953017691
-
Derivation of primary choroid plexus epithelial cells from the mouse
-
Menheniott, T.R., Charalambous, M., Ward, A. Derivation of primary choroid plexus epithelial cells from the mouse. Methods Mol. Biol. 633, 207-220 (2010).
-
(2010)
Methods Mol. Biol.
, vol.633
, pp. 207-220
-
-
Menheniott, T.R.1
Charalambous, M.2
Ward, A.3
-
50
-
-
25444498280
-
TLR signaling tailors innate immune responses in human microglia and astrocytes
-
Jack, C.S. et al. TLR signaling tailors innate immune responses in human microglia and astrocytes. J. Immunol. 175, 4320-4330 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 4320-4330
-
-
Jack, C.S.1
-
51
-
-
84455205524
-
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
-
Alvarez, J.I. et al. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science 334, 1727-1731 (2011).
-
(2011)
Science
, vol.334
, pp. 1727-1731
-
-
Alvarez, J.I.1
|