메뉴 건너뛰기




Volumn 22, Issue 3, 2015, Pages 267-272

New insights in the control of vascular permeability: Vascular endothelial-cadherin and other players

Author keywords

endothelial cells; vascular endothelial cadherin; vascular permeability

Indexed keywords

G PROTEIN ALPHA 13; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

EID: 84928468707     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0000000000000137     Document Type: Review
Times cited : (50)

References (40)
  • 1
    • 84870798143 scopus 로고    scopus 로고
    • The diaphragms of fenestrated endothelia: Gatekeepers of vascular permeability and blood composition
    • Stan RV, Tse D, Deharvengt SJ, et al. The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition. Dev Cell 2012; 23:1203-1218.
    • (2012) Dev Cell , vol.23 , pp. 1203-1218
    • Stan, R.V.1    Tse, D.2    Deharvengt, S.J.3
  • 3
    • 84884149475 scopus 로고    scopus 로고
    • VE-cadherin and endothelial adherens junctions: Active guardians of vascular integrity
    • Giannotta M, Trani M, Dejana E. VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity. Dev Cell 2013; 26:441-454.
    • (2013) Dev Cell , vol.26 , pp. 441-454
    • Giannotta, M.1    Trani, M.2    Dejana, E.3
  • 4
    • 84875241774 scopus 로고    scopus 로고
    • The role of VE-cadherin in vascular morphogenesis and permeability control
    • Dejana E, Vestweber D. The role of VE-cadherin in vascular morphogenesis and permeability control. Prog Mol Biol Transl Sci 2013; 116:119-144.
    • (2013) Prog Mol Biol Transl Sci , vol.116 , pp. 119-144
    • Dejana, E.1    Vestweber, D.2
  • 5
    • 48649101326 scopus 로고    scopus 로고
    • Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
    • Taddei A, Giampietro C, Conti A, et al. Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Nat Cell Biol 2008; 10:923-934.
    • (2008) Nat Cell Biol , vol.10 , pp. 923-934
    • Taddei, A.1    Giampietro, C.2    Conti, A.3
  • 6
    • 84912092373 scopus 로고    scopus 로고
    • Architecture of tight junctions and principles of molecular composition
    • Van Itallie CM, Anderson JM. Architecture of tight junctions and principles of molecular composition. Semin Cell Dev Biol 2014; 36C:157-165.
    • (2014) Semin Cell Dev Biol , vol.36 C , pp. 157-165
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 7
    • 84912105184 scopus 로고    scopus 로고
    • Tight junction, selective permeability, and related diseases
    • Krug SM, Schulzke JD, Fromm M. Tight junction, selective permeability, and related diseases. Semin Cell Dev Biol 2014; 36C:166-176.
    • (2014) Semin Cell Dev Biol , vol.36 C , pp. 166-176
    • Krug, S.M.1    Schulzke, J.D.2    Fromm, M.3
  • 8
    • 84912106825 scopus 로고    scopus 로고
    • The role of molecular remodeling in differential regulation of tight junction permeability
    • Turner JR, Buschmann MM, Romero-Calvo I, et al. The role of molecular remodeling in differential regulation of tight junction permeability. Semin Cell Dev Biol 2014; 36C:204-212.
    • (2014) Semin Cell Dev Biol , vol.36 C , pp. 204-212
    • Turner, J.R.1    Buschmann, M.M.2    Romero-Calvo, I.3
  • 9
    • 77249110786 scopus 로고    scopus 로고
    • Dynamics and functions of tight junctions
    • Steed E, Balda MS, Matter K. Dynamics and functions of tight junctions. Trends Cell Biol 2010; 20:142-149.
    • (2010) Trends Cell Biol , vol.20 , pp. 142-149
    • Steed, E.1    Balda, M.S.2    Matter, K.3
  • 10
    • 33747165872 scopus 로고    scopus 로고
    • Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments
    • Lampugnani MG, Orsenigo F, Gagliani MC, et al. Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments. J Cell Biol 2006; 174:593-604.
    • (2006) J Cell Biol , vol.174 , pp. 593-604
    • Lampugnani, M.G.1    Orsenigo, F.2    Gagliani, M.C.3
  • 11
    • 41949112173 scopus 로고    scopus 로고
    • VE-cadherin is a critical endothelial regulator of TGF-beta signalling
    • Rudini N, Felici A, Giampietro C, et al. VE-cadherin is a critical endothelial regulator of TGF-beta signalling. EMBO J 2008; 27:993-1004.
    • (2008) EMBO J , vol.27 , pp. 993-1004
    • Rudini, N.1    Felici, A.2    Giampietro, C.3
  • 12
    • 84857719747 scopus 로고    scopus 로고
    • Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells
    • Giampietro C, Taddei A, Corada M, et al. Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells. Blood 2012; 119:2159-2170.
    • (2012) Blood , vol.119 , pp. 2159-2170
    • Giampietro, C.1    Taddei, A.2    Corada, M.3
  • 13
    • 14044256553 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues
    • Lambeng N, Wallez Y, Rampon C, et al. Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues. Circ Res 2005; 96:384-391.
    • (2005) Circ Res , vol.96 , pp. 384-391
    • Lambeng, N.1    Wallez, Y.2    Rampon, C.3
  • 14
    • 33847050140 scopus 로고    scopus 로고
    • Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: Identification of tyrosine 685 as the unique target site
    • Wallez Y, Cand F, Cruzalegui F, et al. Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site. Oncogene 2007; 26:1067-1077.
    • (2007) Oncogene , vol.26 , pp. 1067-1077
    • Wallez, Y.1    Cand, F.2    Cruzalegui, F.3
  • 15
    • 77955977167 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling
    • Corada M, Nyqvist D, Orsenigo F, et al. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell 2010; 18:938-949.
    • (2010) Dev Cell , vol.18 , pp. 938-949
    • Corada, M.1    Nyqvist, D.2    Orsenigo, F.3
  • 16
    • 84870688010 scopus 로고    scopus 로고
    • Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
    • Orsenigo F, Giampietro C, Ferrari A, et al. Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat Commun 2012; 3:1208.
    • (2012) Nat Commun , vol.3 , pp. 1208
    • Orsenigo, F.1    Giampietro, C.2    Ferrari, A.3
  • 17
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 18
    • 79960096827 scopus 로고    scopus 로고
    • Normalization of the vasculature for treatment of cancer and other diseases
    • Goel S, Duda DG, Xu L, et al. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev 2011; 91:1071-1121.
    • (2011) Physiol Rev , vol.91 , pp. 1071-1121
    • Goel, S.1    Duda, D.G.2    Xu, L.3
  • 19
    • 79957894276 scopus 로고    scopus 로고
    • Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
    • Carmeliet P, Jain RK. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nature Rev Drug Discov 2011; 10:417-427.
    • (2011) Nature Rev Drug Discov , vol.10 , pp. 417-427
    • Carmeliet, P.1    Jain, R.K.2
  • 20
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
    • Gavard J, Gutkind JS. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat Cell Biol 2006; 8:1223-1234.
    • (2006) Nat Cell Biol , vol.8 , pp. 1223-1234
    • Gavard, J.1    Gutkind, J.S.2
  • 21
    • 70350015332 scopus 로고    scopus 로고
    • The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species
    • Monaghan-Benson E, Burridge K. The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem 2009; 284:25602-25611.
    • (2009) J Biol Chem , vol.284 , pp. 25602-25611
    • Monaghan-Benson, E.1    Burridge, K.2
  • 22
    • 77951212625 scopus 로고    scopus 로고
    • Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers
    • Adam AP, Sharenko AL, Pumiglia K, et al. Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J Biol Chem 2010; 285:7045-7055.
    • (2010) J Biol Chem , vol.285 , pp. 7045-7055
    • Adam, A.P.1    Sharenko, A.L.2    Pumiglia, K.3
  • 23
    • 84894470051 scopus 로고    scopus 로고
    • Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin
    • Wessel F, Winderlich M, Holm M, et al. Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin. Nat Immunol 2014; 15:223-230.
    • (2014) Nat Immunol , vol.15 , pp. 223-230
    • Wessel, F.1    Winderlich, M.2    Holm, M.3
  • 24
    • 84861302593 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2
    • Hatanaka K, Lanahan AA, Murakami M, et al. Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2. PloS One 2012; 7:e37600.
    • (2012) PloS One , vol.7 , pp. e37600
    • Hatanaka, K.1    Lanahan, A.A.2    Murakami, M.3
  • 25
    • 11144357189 scopus 로고    scopus 로고
    • Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction
    • Weis S, Shintani S, Weber A, et al. Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. J Clin Invest 2004; 113:885-894.
    • (2004) J Clin Invest , vol.113 , pp. 885-894
    • Weis, S.1    Shintani, S.2    Weber, A.3
  • 26
    • 84864292241 scopus 로고    scopus 로고
    • VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd
    • Sun Z, Li X, Massena S, et al. VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd. J Exp Med 2012; 209:1363-1377.
    • (2012) J Exp Med , vol.209 , pp. 1363-1377
    • Sun, Z.1    Li, X.2    Massena, S.3
  • 27
    • 37449026980 scopus 로고    scopus 로고
    • Defining the function of betacatenin tyrosine phosphorylation in cadherin-mediated cell-cell adhesion
    • Tominaga J, Fukunaga Y, Abelardo E, et al. Defining the function of betacatenin tyrosine phosphorylation in cadherin-mediated cell-cell adhesion. Genes Cells 2008; 13:67-77.
    • (2008) Genes Cells , vol.13 , pp. 67-77
    • Tominaga, J.1    Fukunaga, Y.2    Abelardo, E.3
  • 28
    • 0030908042 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells
    • Abedi H, Zachary I. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells. J Biol Chem 1997; 272:15442-15451.
    • (1997) J Biol Chem , vol.272 , pp. 15442-15451
    • Abedi, H.1    Zachary, I.2
  • 29
    • 76049104513 scopus 로고    scopus 로고
    • Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment
    • Liang W, Kujawski M, Wu J, et al. Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment. Clin Cancer Res 2010; 16:924-935.
    • (2010) Clin Cancer Res , vol.16 , pp. 924-935
    • Liang, W.1    Kujawski, M.2    Wu, J.3
  • 30
    • 84862907457 scopus 로고    scopus 로고
    • VEGF-induced vascular permeability is mediated by FAK
    • Chen XL, Nam JO, Jean C, et al. VEGF-induced vascular permeability is mediated by FAK. Dev Cell 2012; 22:146-157.
    • (2012) Dev Cell , vol.22 , pp. 146-157
    • Chen, X.L.1    Nam, J.O.2    Jean, C.3
  • 31
    • 84892894930 scopus 로고    scopus 로고
    • Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function
    • Jean C, Chen XL, Nam JO, et al. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. J Cell Biol 2014; 204:247-263.
    • (2014) J Cell Biol , vol.204 , pp. 247-263
    • Jean, C.1    Chen, X.L.2    Nam, J.O.3
  • 33
    • 0031015426 scopus 로고    scopus 로고
    • Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
    • Offermanns S, Mancino V, Revel JP, et al. Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science 1997; 275:533-536.
    • (1997) Science , vol.275 , pp. 533-536
    • Offermanns, S.1    Mancino, V.2    Revel, J.P.3
  • 34
    • 0043237427 scopus 로고    scopus 로고
    • Protein kinase C alpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement
    • Holinstat M, Mehta D, Kozasa T, et al. Protein kinase C alpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. J Biol Chem 2003; 278:28793-28798.
    • (2003) J Biol Chem , vol.278 , pp. 28793-28798
    • Holinstat, M.1    Mehta, D.2    Kozasa, T.3
  • 35
    • 20444423842 scopus 로고    scopus 로고
    • Essential role for Galpha13 in endothelial cells during embryonic development
    • Ruppel KM, Willison D, Kataoka H, et al. Essential role for Galpha13 in endothelial cells during embryonic development. Proc Natl Acad Sci USA 2005; 102:8281-8286.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8281-8286
    • Ruppel, K.M.1    Willison, D.2    Kataoka, H.3
  • 36
    • 70350448475 scopus 로고    scopus 로고
    • Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency
    • Chen L, Zhang JJ, Rafii S, et al. Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency. J Biol Chem 2009; 284:27409-27415.
    • (2009) J Biol Chem , vol.284 , pp. 27409-27415
    • Chen, L.1    Zhang, J.J.2    Rafii, S.3
  • 37
    • 0035941263 scopus 로고    scopus 로고
    • Distinct regions of the cadherin cytoplasmic domain are essential for functional interaction with Galpha 12 and betacatenin
    • Kaplan DD, Meigs TE, Casey PJ. Distinct regions of the cadherin cytoplasmic domain are essential for functional interaction with Galpha 12 and betacatenin. J Biol Chem 2001; 276:44037-44043.
    • (2001) J Biol Chem , vol.276 , pp. 44037-44043
    • Kaplan, D.D.1    Meigs, T.E.2    Casey, P.J.3
  • 38
    • 77952047728 scopus 로고    scopus 로고
    • Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels
    • Turm H,Maoz M, Katz V, et al. Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels. J Biol Chem 2010; 285:15137-15148.
    • (2010) J Biol Chem , vol.285 , pp. 15137-15148
    • Turm, H.1    Maoz, M.2    Katz, V.3
  • 39
    • 84896846354 scopus 로고    scopus 로고
    • Evidence of a common mechanism of disassembly of adherens junctions through Galpha13 targeting of VE-cadherin
    • Gong H, Gao X, Feng S, et al. Evidence of a common mechanism of disassembly of adherens junctions through Galpha13 targeting of VE-cadherin. J Exp Med 2014; 211:579-591.
    • (2014) J Exp Med , vol.211 , pp. 579-591
    • Gong, H.1    Gao, X.2    Feng, S.3
  • 40
    • 77954334673 scopus 로고    scopus 로고
    • Role of GTPases in control of microvascular permeability
    • Spindler V, Schlegel N, Waschke J. Role of GTPases in control of microvascular permeability. Cardiovasc Res 2010; 87:243-253.
    • (2010) Cardiovasc Res , vol.87 , pp. 243-253
    • Spindler, V.1    Schlegel, N.2    Waschke, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.