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Volumn 101, Issue 3, 2015, Pages 487-495

Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: A randomized clinical trial

Author keywords

Calorimetry; Energy metabolism; Epigallocatechin 3 gallate; Microdialysis; Multiple sclerosis; Sex difference

Indexed keywords

CARBOHYDRATE; EPIGALLOCATECHIN GALLATE; FAT; GLATIRAMER; GLUCOSE; PLACEBO; CATECHIN; IMMUNOSUPPRESSIVE AGENT; NEUROPROTECTIVE AGENT; PEPTIDE;

EID: 84928430504     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.113.075309     Document Type: Article
Times cited : (71)

References (50)
  • 1
    • 84865584896 scopus 로고    scopus 로고
    • Multiple sclerosis lesions and irreversible brain tissue damage: A comparative ultrahigh-field strength magnetic resonance imaging study
    • Sinnecker T, Mittelstaedt P, Dorr J, Pfueller CF, Harms L, Niendorf T, Paul F, Wuerfel J. Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study. Arch Neurol 2012;69:739-45.
    • (2012) Arch Neurol , vol.69 , pp. 739-745
    • Sinnecker, T.1    Mittelstaedt, P.2    Dorr, J.3    Pfueller, C.F.4    Harms, L.5    Niendorf, T.6    Paul, F.7    Wuerfel, J.8
  • 2
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A. Multiple sclerosis. Lancet 2008;372:1502-17.
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 4
    • 78650172976 scopus 로고    scopus 로고
    • Inflammation, demyelination, and degeneration-recent insights from MS pathology
    • Stadelmann C, Wegner C, Bruck W. Inflammation, demyelination, and degeneration-recent insights from MS pathology. Biochim Biophys Acta 2011;1812:275-82.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 275-282
    • Stadelmann, C.1    Wegner, C.2    Bruck, W.3
  • 5
    • 67649359872 scopus 로고    scopus 로고
    • Fatigued patients with multiple sclerosis have impaired central muscle activation
    • Andreasen AK, Jakobsen J, Petersen T, Andersen H. Fatigued patients with multiple sclerosis have impaired central muscle activation. Mult Scler 2009;15:818-27.
    • (2009) Mult Scler , vol.15 , pp. 818-827
    • Andreasen, A.K.1    Jakobsen, J.2    Petersen, T.3    Andersen, H.4
  • 7
    • 84883757689 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate: A useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?
    • Mähler A, Mandel S, Lorenz M, Ruegg U, Wanker EE, Boschmann M, Paul F. Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases? EPMA J 2013;4:5.
    • (2013) EPMA J , vol.4 , pp. 5
    • Mähler, A.1    Mandel, S.2    Lorenz, M.3    Ruegg, U.4    Wanker, E.E.5    Boschmann, M.6    Paul, F.7
  • 9
    • 80054087636 scopus 로고    scopus 로고
    • Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation
    • Herges K, Millward JM, Hentschel N, Infante-Duarte C, Aktas O, Zipp F. Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation. PLoS ONE 2011; 6:e25456.
    • (2011) PLoS ONE , vol.6 , pp. e25456
    • Herges, K.1    Millward, J.M.2    Hentschel, N.3    Infante-Duarte, C.4    Aktas, O.5    Zipp, F.6
  • 10
    • 83455258147 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate ameliorates experimental autoimmune encephalomyelitis by altering balance among CD4+ T-cell subsets
    • Wang J, Ren Z, Xu Y, Xiao S, Meydani SN, Wu D. Epigallocatechin-3-gallate ameliorates experimental autoimmune encephalomyelitis by altering balance among CD4+ T-cell subsets. Am J Pathol 2012;180: 221-34.
    • (2012) Am J Pathol , vol.180 , pp. 221-234
    • Wang, J.1    Ren, Z.2    Xu, Y.3    Xiao, S.4    Meydani, S.N.5    Wu, D.6
  • 11
    • 0036291378 scopus 로고    scopus 로고
    • Regulation of fat metabolism in skeletal muscle
    • Jeukendrup AE. Regulation of fat metabolism in skeletal muscle. Ann N Y Acad Sci 2002;967:217-35.
    • (2002) Ann N y Acad Sci , vol.967 , pp. 217-235
    • Jeukendrup, A.E.1
  • 13
    • 84882243236 scopus 로고    scopus 로고
    • The effect of green tea extract on fat oxidation at rest and during exercise: Evidence of efficacy and proposed mechanisms
    • Hodgson AB, Randell RK, Jeukendrup AE. The effect of green tea extract on fat oxidation at rest and during exercise: evidence of efficacy and proposed mechanisms. Adv Nutr 2013;4:129-40.
    • (2013) Adv Nutr , vol.4 , pp. 129-140
    • Hodgson, A.B.1    Randell, R.K.2    Jeukendrup, A.E.3
  • 15
    • 77955385260 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?
    • Witte ME, Geurts JJ, de Vries HE, van der Valk P, van Horssen J. Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion 2010;10:411-8.
    • (2010) Mitochondrion , vol.10 , pp. 411-418
    • Witte, M.E.1    Geurts, J.J.2    De Vries, H.E.3    Van Der-Valk, P.4    Van Horssen, J.5
  • 18
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 19
    • 77957019665 scopus 로고    scopus 로고
    • The effect of ascorbic acid, citric acid and low pH on the extraction of green tea: How to get most out of it
    • Zimmermann BF, Gleichenhagen M. The effect of ascorbic acid, citric acid and low pH on the extraction of green tea: how to get most out of it. Food Chem 2010;124:1543-8.
    • (2010) Food Chem , vol.124 , pp. 1543-1548
    • Zimmermann, B.F.1    Gleichenhagen, M.2
  • 20
    • 0023930822 scopus 로고
    • The theoretical bases of indirect calorimetry: A review
    • Ferrannini E. The theoretical bases of indirect calorimetry: a review. Metabolism 1988;37:287-301.
    • (1988) Metabolism , vol.37 , pp. 287-301
    • Ferrannini, E.1
  • 21
    • 3142768439 scopus 로고    scopus 로고
    • The reproducibility of perceptually regulated exercise responses during short-term cycle ergometry
    • Hartshorn JE, Lamb KL. The reproducibility of perceptually regulated exercise responses during short-term cycle ergometry. Int J Sports Med 2004;25:362-7.
    • (2004) Int J Sports Med , vol.25 , pp. 362-367
    • Hartshorn, J.E.1    Lamb, K.L.2
  • 23
    • 0029978291 scopus 로고    scopus 로고
    • Evaluation of the microdialysis ethanol technique for monitoring of subcutaneous adipose tissue blood flow in humans
    • Felländer G, Linde B, Bolinder J. Evaluation of the microdialysis ethanol technique for monitoring of subcutaneous adipose tissue blood flow in humans. Int J Obes Relat Metab Disord 1996;20:220-6.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 220-226
    • Felländer, G.1    Linde, B.2    Bolinder, J.3
  • 24
    • 0025804750 scopus 로고
    • A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis
    • Ståhle L, Segersvard S, Ungerstedt U. A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis. J Pharmacol Methods 1991;25:41-52.
    • (1991) J Pharmacol Methods , vol.25 , pp. 41-52
    • Ståhle, L.1    Segersvard, S.2    Ungerstedt, U.3
  • 25
    • 77955013378 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: A pilot study
    • Thielecke F, Rahn G, Bohnke J, Adams F, Birkenfeld AL, Jordan J, Boschmann M. Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study. Eur J Clin Nutr 2010;64:704-13.
    • (2010) Eur J Clin Nutr , vol.64 , pp. 704-713
    • Thielecke, F.1    Rahn, G.2    Bohnke, J.3    Adams, F.4    Birkenfeld, A.L.5    Jordan, J.6    Boschmann, M.7
  • 26
    • 22844435525 scopus 로고    scopus 로고
    • TEAVIGO (epigallocatechin gallate) supplementation prevents obesity in rodents by reducing adipose tissue mass
    • Wolfram S, Raederstorff D, Wang Y, Teixeira SR, Elste V, Weber P. TEAVIGO (epigallocatechin gallate) supplementation prevents obesity in rodents by reducing adipose tissue mass. Ann Nutr Metab 2005;49: 54-63.
    • (2005) Ann Nutr Metab , vol.49 , pp. 54-63
    • Wolfram, S.1    Raederstorff, D.2    Wang, Y.3    Teixeira, S.R.4    Elste, V.5    Weber, P.6
  • 27
    • 20044383992 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation
    • Klaus S, Pultz S, Thone-Reineke C, Wolfram S. Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation. Int J Obes (Lond) 2005;29: 615-23.
    • (2005) Int J Obes (Lond) , vol.29 , pp. 615-623
    • Klaus, S.1    Pultz, S.2    Thone-Reineke, C.3    Wolfram, S.4
  • 29
    • 84885821596 scopus 로고    scopus 로고
    • Risk factors related to cardiovascular diseases and the metabolic syndrome in multiple sclerosis-A systematic review
    • Wens I, Dalgas U, Stenager E, Eijnde BO. Risk factors related to cardiovascular diseases and the metabolic syndrome in multiple sclerosis-a systematic review. Mult Scler 2013;19:1556-64.
    • (2013) Mult Scler , vol.19 , pp. 1556-1564
    • Wens, I.1    Dalgas, U.2    Stenager, E.3    Eijnde, B.O.4
  • 30
    • 38149045842 scopus 로고    scopus 로고
    • Molecular modelling study of the mechanism of high-potency inhibition of human catechol-Omethyltransferase by (-)-epigallocatechin-3-O-gallate
    • Zhu BT, Shim JY, Nagai M, Bai HW. Molecular modelling study of the mechanism of high-potency inhibition of human catechol-Omethyltransferase by (-)-epigallocatechin-3-O-gallate. Xenobiotica 2008;38:130-46.
    • (2008) Xenobiotica , vol.38 , pp. 130-146
    • Zhu, B.T.1    Shim, J.Y.2    Nagai, M.3    Bai, H.W.4
  • 31
    • 84919461856 scopus 로고    scopus 로고
    • The activity of catechol-O-methyltransferase (COMT) is not impaired by high doses of epigallocatechin-3-gallate (EGCG) in vivo
    • Lorenz M, Paul F, Moobed M, Baumann G, Zimmermann BF, Stangl K, Stangl V. The activity of catechol-O-methyltransferase (COMT) is not impaired by high doses of epigallocatechin-3-gallate (EGCG) in vivo. Eur J Pharmacol 2014;740:645-51.
    • (2014) Eur J Pharmacol , vol.740 , pp. 645-651
    • Lorenz, M.1    Paul, F.2    Moobed, M.3    Baumann, G.4    Zimmermann, B.F.5    Stangl, K.6    Stangl, V.7
  • 32
    • 26044451440 scopus 로고    scopus 로고
    • Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men
    • Bérubé-Parent S, Pelletier C, Dore J, Tremblay A. Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men. Br J Nutr 2005;94:432-6.
    • (2005) Br J Nutr , vol.94 , pp. 432-436
    • Bérubé-Parent, S.1    Pelletier, C.2    Dore, J.3    Tremblay, A.4
  • 35
    • 0032805656 scopus 로고    scopus 로고
    • Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans
    • Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr 1999;70:1040-5.
    • (1999) Am J Clin Nutr , vol.70 , pp. 1040-1045
    • Dulloo, A.G.1    Duret, C.2    Rohrer, D.3    Girardier, L.4    Mensi, N.5    Fathi, M.6    Chantre, P.7    Vandermander, J.8
  • 36
    • 35348901383 scopus 로고    scopus 로고
    • The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: A pilot study
    • Boschmann M, Thielecke F. The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study. J Am Coll Nutr 2007;26:389S-95S.
    • (2007) J Am Coll Nutr , vol.26 , pp. 389S-95S
    • Boschmann, M.1    Thielecke, F.2
  • 38
    • 0029742073 scopus 로고    scopus 로고
    • Thermic effect of food and sympathetic nervous system activity in humans
    • Tappy L. Thermic effect of food and sympathetic nervous system activity in humans. Reprod Nutr Dev 1996;36:391-7.
    • (1996) Reprod Nutr Dev , vol.36 , pp. 391-397
    • Tappy, L.1
  • 40
    • 33644854366 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex
    • Rodriguez SK, Guo W, Liu L, Band MA, Paulson EK, Meydani M. Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex. Int J Cancer 2006;118:1635-44.
    • (2006) Int J Cancer , vol.118 , pp. 1635-1644
    • Rodriguez, S.K.1    Guo, W.2    Liu, L.3    Band, M.A.4    Paulson, E.K.5    Meydani, M.6
  • 44
    • 0021742028 scopus 로고
    • Thermic effect of food during graded exercise in normal weight and obese men
    • Segal KR, Presta E, Gutin B. Thermic effect of food during graded exercise in normal weight and obese men. Am J Clin Nutr 1984;40: 995-1000.
    • (1984) Am J Clin Nutr , vol.40 , pp. 995-1000
    • Segal, K.R.1    Presta, E.2    Gutin, B.3
  • 45
    • 0038759734 scopus 로고    scopus 로고
    • Intra-individual variation in resting metabolic rate during the menstrual cycle
    • Henry CJ, Lightowler HJ, Marchini J. Intra-individual variation in resting metabolic rate during the menstrual cycle. Br J Nutr 2003;89: 811-7.
    • (2003) Br J Nutr , vol.89 , pp. 811-817
    • Henry, C.J.1    Lightowler, H.J.2    Marchini, J.3
  • 46
    • 0036087641 scopus 로고    scopus 로고
    • No effect of menstrual cycle phase on glucose kinetics and fuel oxidation during moderate-intensity exercise
    • Horton TJ, Miller EK, Glueck D, Tench K. No effect of menstrual cycle phase on glucose kinetics and fuel oxidation during moderate-intensity exercise. Am J Physiol Endocrinol Metab 2002;282: E752-62.
    • (2002) Am J Physiol Endocrinol Metab , vol.282 , pp. E752-E762
    • Horton, T.J.1    Miller, E.K.2    Glueck, D.3    Tench, K.4
  • 47
    • 0030871204 scopus 로고    scopus 로고
    • Thermic effect of food during each phase of the menstrual cycle
    • Tai MM, Castillo TP, Pi-Sunyer FX. Thermic effect of food during each phase of the menstrual cycle. Am J Clin Nutr 1997;66:1110-5.
    • (1997) Am J Clin Nutr , vol.66 , pp. 1110-1115
    • Tai, M.M.1    Castillo, T.P.2    Pi-Sunyer, F.X.3
  • 48
    • 0029838719 scopus 로고    scopus 로고
    • Postabsorptive and postprandial energy expenditure and substrate oxidation do not change during the menstrual cycle in young women
    • Melanson KJ, Saltzman E, Russell R, Roberts SB. Postabsorptive and postprandial energy expenditure and substrate oxidation do not change during the menstrual cycle in young women. J Nutr 1996;126:2531-8.
    • (1996) J Nutr , vol.126 , pp. 2531-2538
    • Melanson, K.J.1    Saltzman, E.2    Russell, R.3    Roberts, S.B.4
  • 49
    • 0024560441 scopus 로고
    • Changes in energy expenditure during the menstrual cycle
    • Bisdee JT, James WP, Shaw MA. Changes in energy expenditure during the menstrual cycle. Br J Nutr 1989;61:187-99.
    • (1989) Br J Nutr , vol.61 , pp. 187-199
    • Bisdee, J.T.1    James, W.P.2    Shaw, M.A.3
  • 50
    • 0023025663 scopus 로고
    • 24-Hour energy expenditure and the menstrual cycle
    • Webb P. 24-Hour energy expenditure and the menstrual cycle. Am J Clin Nutr 1986;44:614-9.
    • (1986) Am J Clin Nutr , vol.44 , pp. 614-619
    • Webb, P.1


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