Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans

American Journal of Clinical Nutrition

Volumn 70, Issue 6, 1999, Pages 1040-1045

  Dulloo, Abdul G ^a   Duret, Claudette ^b   Rohrer, Dorothée ^b   Girardier, Lucien ^b   Mensi, Nouri ^b   Fathi, Marc ^b   Chantre, Philippe ^b   Vandermander, Jacques ^b  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b NONE

Author keywords

Caffeine; Catechins; Catecholamines; Fat oxidation; Green tea; Men; Obesity; Polyphenols; Sympathetic nervous system; Thermogenesis

Indexed keywords

CAFFEINE; CATECHIN; CATECHOLAMINE; EPIGALLOCATECHIN GALLATE; FAT; NITROGEN; NORADRENALIN; PLACEBO; POLYPHENOL DERIVATIVE;

ADULT; ARTICLE; BODY COMPOSITION; CATECHOLAMINE URINE LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENERGY EXPENDITURE; FATTY ACID OXIDATION; HUMAN; HUMAN EXPERIMENT; MALE; NITROGEN URINE LEVEL; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY QUOTIENT; SYMPATHETIC TONE; TEA; THERMOGENESIS; WEIGHT REDUCTION;

EID: 0032805656     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/70.6.1040     Document Type: Article

References (23)

1. Landsberg L, Young JB. Sympathoadrenal activity and obesity: physiological rationale for the use of adrenergic thermogenic drugs. Int J Obes Relat Metab Disord 1993;65:S29-34.
2. Dulloo AG. Strategies to counteract readjustments towards lower metabolic rates during obesity management. Nutrition 1993;9:366-72.
3. 3,-adrenoceptor agonists in the treatment of obesity and diabetes. Int J Obes Relat Metab Disord 1996;20:191-9.
4. Dulloo AG. Spicing fat for combustion. Br J Nutr 1998;80:493-4.
5. Henry CJK, Emery B. Effects of spiced food on metabolic rate. Hum Nutr Clin Nutr 1986;40C:165-8.
6. Yoshioka M, St-Pierre S, Suzuki M, Tremblay A. Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. Br J Nutr 1998;80:503-10.
7. Dulloo AG. Ephedrine, xanthines and prostaglandin-inhibitors: actions and interactions in the stimulation of thermogenesis. Int J Obes Relat Metab Disord 1993;17:835-40.
8. Toubro S, Astrup A, Breum L, Quaade F. Safety and efficacy of long-term treatment with ephedrine, caffeine and an ephedrine/ caffeine mixture. Int J Obes Relat Metab Disord 1993;17:S69-72.
9. Dulloo AG, Seydoux J, Girardier L. Potentiation of the thermogenic antiobesity effects of ephedrine by dietary methylxanthines: adenosine antagonism or phosphodiesterase inhibition? Metabolism 1992;41:1233-41.
10. Durand J, Giacobino JP, Girardier L. Catechol-O-methyl-transferase activity in whole brown adipose tissue of rat in vitro. In: Girardier L, Seydoux J, eds. Effectors of thermogenesis. Basel, Switzerland: Birkhauser, 1977:45-53.
11. Borchardt RT, Huber JA. Catechol-O-methyltransferase: structure-activity relationships for inhibition by flavonoids. J Med Chem 1975;18:120-2.
12. Dulloo AG, Seydoux J, Girardier L. Tealine and thermogenesis: interactions between polyphenols, caffeine and sympathetic activity. Int J Obes Relat Metab Disord 1996;20(suppl):71(abstr).
13. Durnin JVGA, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness measurements of 481 men and women aged 16-72 years. Br J Nutr 1974;32:77-97.
14. Stagg GV, Millin DJ. The nutritional and therapeutic value of tea -a review. J Sci Food Agric 1975;26:1439-59.
15. Cunningham JJ. Body composition as a determinant of energy expenditure: a synthetic review and a proposed general prediction equation. Am J Clin Nutr 1991;54:963-9.
16. Dulloo AG, Fathi M, Mensi N, Girardier L. Twenty-four hour energy expenditure and urinary catecholamines of humans consuming low-to-moderate amounts of medium-chain-triglycerides: a dose-response study in a respiratory chamber. Eur J Clin Nutr 1996;50:152-8.
17. Jequier E, Acheson KJ, Schutz Y. Assessment of energy expenditure and fuel utilization in man. Annu Rev Nutr 1987;7:187-208.
18. Dulloo AG, Geissler CA, Horton T. Collins A, Miller DS. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and post-obese human volunteers. Am J Clin Nutr 1989;49:44-50.
19. Bracco D, Ferrarra JM, Arnaud MJ, Jéquier E, Schutz Y Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women. Am J Physiol 1995;269:E671-8.
20. Dulloo AG, Seydoux J, Girardier L, Chantra P, Vandermander J. Green tea and thermogenesis: interactions between catechinpolyphenols, caffeine and sympathetic activity. Int J Obes Relat Metab Disord (in press).
21. Lee MJ, Wang ZY, Li H, et al. Analysis of plasma and urinary tea polyphenols in human subjects. Cancer Epidemiol Biomarkers Prev 1995;44:393-9.
22. Hollman PCH, Tijburg LBM, Yang CS. Bioavailability of flavonoids from tea. Crit Rev Food Sci Nutr 1997;37:719-38.
23. Dulloo AG, Miller DS. The thermogenic properties of ephedrine/ methylxanthine mixtures: human studies. Int J Obes 1986;10: 467-81.