The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Aggarwal, Abhishek ^a   Prinz Wohlgenannt, Maximilian ^a   Gröschel, Charlotte ^a   Tennakoon, Samawansha ^a   Meshcheryakova, Anastasia ^a   Chang, Wenhan ^b   Brown, Edward M ^c   Mechtcheriakova, Diana ^a   Kállay, Enikö ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Calcimimetic; Calcium sensing receptor; Cancer; Cancer stem cell; Colon; EMT; Inflammation; Tumor suppressor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTINEOPLASTIC AGENT; BETA CATENIN; CALCIUM SENSING RECEPTOR; CALVASCULIN; CYCLIN D1; MESSENGER RNA; PARATHYROID HORMONE; PROTEIN; STELLA PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST 2; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WNT PROTEIN; CADHERIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; GSK3B PROTEIN, HUMAN; GSK3B PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL ADHESION; CELL COUNT; CELL GROWTH; CELL INVASION; CELL MIGRATION; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EXON; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENE TRANSLOCATION; GROWTH INHIBITION; HT 29 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STABLE EXPRESSION; STABLE TRANSFECTION; TUMOR INVASION; UPREGULATION; ANIMAL; COLON; COLON TUMOR; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HT-29 CELL LINE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; STEM CELL; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

MUS;

ANIMALS; BETA CATENIN; CADHERINS; CELL LINE, TUMOR; COLON; COLONIC NEOPLASMS; CYCLIN D1; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HT29 CELLS; HUMANS; MICE; MICE, KNOCKOUT; PHENOTYPE; RECEPTORS, CALCIUM-SENSING; STEM CELLS; TRANSCRIPTION, GENETIC; UP-REGULATION; WNT SIGNALING PATHWAY;

EID: 84928398109     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0330-4     Document Type: Article

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