Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

International Journal of Cancer

Volumn 135, Issue 9, 2014, Pages 2014-2023

  Fetahu, Irfete S ^a   Höbaus, Julia ^a   Aggarwal, Abhishek ^a   Hummel, Doris M ^a   Tennakoon, Samawansha ^a   Mesteri, Ildiko ^a   Baumgartner Parzer, Sabina ^a   Kállay, Enikö ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

calcium sensing receptor; colorectal cancer; DNA methylation; histone acetylation; histone methylation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CALCIUM SENSING RECEPTOR; DNA METHYLTRANSFERASE 1; HISTONE DEACETYLASE; HISTONE H3; LYSINE SPECIFIC DEMETHYLASE 1; MESSENGER RNA; METHYLTRANSFERASE; TRICHOSTATIN A; UNCLASSIFIED DRUG; VORINOSTAT;

AGED; ARTICLE; CANCER CELL; CASR GENE; CELL PROLIFERATION; COHORT ANALYSIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; DEACETYLATION; DNA METHYLATION; DNA SEQUENCE; DOWN REGULATION; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GENE SILENCING; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PYROSEQUENCING; UPREGULATION;

CALCIUM-SENSING RECEPTOR; COLORECTAL CANCER; DNA METHYLATION; HISTONE ACETYLATION; HISTONE METHYLATION;

ACETYLATION; AGED; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COLORECTAL NEOPLASMS; DNA METHYLATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYDROXAMIC ACIDS; MALE; NEOPLASM GRADING; NEOPLASM STAGING; PROGNOSIS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CALCIUM-SENSING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 84906262618     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28856     Document Type: Article

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