Denbinobin, a phenanthrene from dendrobium nobile, impairs prostate cancer migration by inhibiting Rac1 activity

American Journal of Chinese Medicine

Volumn 42, Issue 6, 2014, Pages 1539-1554

  Lu, Te Ling ^a   Han, Chien Kuo ^b   Chang, Yuan Shiun ^a   Lu, Te Jung ^d   Huang, Hui Chi ^a   Bao, Bo Ying ^a   Wu, Hsing Yu ^a   Huang, Chieh Hung ^c   Li, Chia Yen ^c   Wu, Tian Shung ^e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c NATIONAL PINGTUNG UNIVERSITY   (Taiwan)

^d CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Cortactin; Denbinobin; Lamellipodia; Prostate Cancer; Rac1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CORTACTIN; DENBINOBIN; DNA; PHENANTHRENE; PHOSPHOTRANSFERASE; RAC1 PROTEIN; SRC KINASE; UNCLASSIFIED DRUG; ACTINS; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMOKINE CXCL12; CXCL12 PROTEIN, HUMAN; PHENANTHRENES; RAC1 GTP-BINDING PROTEIN; RAC1 PROTEIN, HUMAN;

ACTIN POLYMERIZATION; ARTICLE; CELL CYCLE M PHASE; CELL CYCLE PHASE; CELL CYCLE PROGRESSION; CELL MIGRATION; CELL VIABILITY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDROBIUM NOBILE; DNA CONTENT; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; MTS ASSAY; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL MOVEMENT; CHEMISTRY; DENDROBIUM; DRUG EFFECTS; HUMANS; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; POLYMERIZATION; PROSTATIC NEOPLASMS; PSEUDOPODIA; TUMOR CELLS, CULTURED;

ACTINS; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL MOVEMENT; CHEMOKINE CXCL12; CORTACTIN; DENDROBIUM; HUMANS; MALE; PHENANTHRENES; PHOSPHORYLATION; POLYMERIZATION; PROSTATIC NEOPLASMS; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; TUMOR CELLS, CULTURED;

EID: 84928394763     PISSN: 0192415X     EISSN: 17936853     Source Type: Journal    
DOI: 10.1142/S0192415X14500967     Document Type: Article

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