CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 9, 2012, Pages

  Ghosh, Manik C ^a   Makena, Patrudu S ^a   Gorantla, Vijay ^a   Sinclair, Scott E ^a   Waters, Christopher M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Epithelial repair

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GELATINASE A; PLERIXAFOR; RAC1 PROTEIN; SHORT HAIRPIN RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ASSAY; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; GENE SILENCING; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; LUNG LAVAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TIDAL VOLUME; WOUND;

ACTIN CYTOSKELETON; ACUTE LUNG INJURY; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL12; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HETEROCYCLIC COMPOUNDS; MALE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MICE; PRIMARY CELL CULTURE; PULMONARY ALVEOLI; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; TISSUE INHIBITOR OF METALLOPROTEINASE-3; UP-REGULATION;

EID: 84860504639     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00321.2011     Document Type: Article

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