-
2
-
-
84895745240
-
A unified view of how allostery works
-
Tsai C.-J., Nussinov R. A unified view of how allostery works. PLoS Comput Biol 2014, 10:e1003394.
-
(2014)
PLoS Comput Biol
, vol.10
, pp. e1003394
-
-
Tsai, C.-J.1
Nussinov, R.2
-
3
-
-
84876709135
-
Allo-network drugs: extension of the allosteric drug concept to protein-protein interaction and signaling networks
-
Szilágyi A., Nussinov R. Allo-network drugs: extension of the allosteric drug concept to protein-protein interaction and signaling networks. Curr Top Med Chem 2013, 13:64-77.
-
(2013)
Curr Top Med Chem
, vol.13
, pp. 64-77
-
-
Szilágyi, A.1
Nussinov, R.2
-
4
-
-
84907979005
-
Harnessing allostery a novel approach to drug discovery
-
Lu S., Li S., Zhang J. Harnessing allostery a novel approach to drug discovery. Med Res Rev 2014, 34:1242-1285.
-
(2014)
Med Res Rev
, vol.34
, pp. 1242-1285
-
-
Lu, S.1
Li, S.2
Zhang, J.3
-
5
-
-
84877580262
-
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
-
Csermely P., Korcsmáros T., Kiss H.J.M., London G., Nussinov R. Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. Pharmacol Ther 2013, 138:333-408.
-
(2013)
Pharmacol Ther
, vol.138
, pp. 333-408
-
-
Csermely, P.1
Korcsmáros, T.2
Kiss, H.J.M.3
London, G.4
Nussinov, R.5
-
6
-
-
84861219631
-
Allostery and the Monod-Wyman-Changeux model after 50 years
-
Changeux J.-P. Allostery and the Monod-Wyman-Changeux model after 50 years. Annu Rev Biophys 2012, 41:103-133.
-
(2012)
Annu Rev Biophys
, vol.41
, pp. 103-133
-
-
Changeux, J.-P.1
-
7
-
-
84888333782
-
50 years of allosteric interactions: the twists and turns of the models
-
Changeux J.P. 50 years of allosteric interactions: the twists and turns of the models. Nat Chem Biol 2013, 14:819-829.
-
(2013)
Nat Chem Biol
, vol.14
, pp. 819-829
-
-
Changeux, J.P.1
-
8
-
-
0021658956
-
Allostery without conformational change. A plausible model
-
Cooper A., Dryden D.T. Allostery without conformational change. A plausible model. Eur Biophys J 1984, 11:103-109.
-
(1984)
Eur Biophys J
, vol.11
, pp. 103-109
-
-
Cooper, A.1
Dryden, D.T.2
-
9
-
-
84901660019
-
NbIT-a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT
-
LeVine M.V., Weinstein H. NbIT-a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT. PLoS Comput Biol 2014, 10:e1003603-e1003615.
-
(2014)
PLoS Comput Biol
, vol.10
, pp. e1003603-e1003615
-
-
LeVine, M.V.1
Weinstein, H.2
-
10
-
-
24744470578
-
Probing the binding entropy of ligand-protein interactions by NMR
-
Homans S.W. Probing the binding entropy of ligand-protein interactions by NMR. ChemBioChem 2005, 6:1585-1591.
-
(2005)
ChemBioChem
, vol.6
, pp. 1585-1591
-
-
Homans, S.W.1
-
11
-
-
79952685998
-
A geometry-based generic predictor for catalytic and allosteric sites
-
Mitternacht S., Berezovsky I.N. A geometry-based generic predictor for catalytic and allosteric sites. Protein Eng Des Sel 2011, 24:405-409.
-
(2011)
Protein Eng Des Sel
, vol.24
, pp. 405-409
-
-
Mitternacht, S.1
Berezovsky, I.N.2
-
12
-
-
84875170915
-
Protein contact networks: an emerging paradigm in chemistry
-
Di Paola L., De Ruvo M., Paci P., Santoni D., Giuliani A. Protein contact networks: an emerging paradigm in chemistry. Chem Rev 2013, 113:1598-1613.
-
(2013)
Chem Rev
, vol.113
, pp. 1598-1613
-
-
Di Paola, L.1
De Ruvo, M.2
Paci, P.3
Santoni, D.4
Giuliani, A.5
-
13
-
-
84903215285
-
Allosteric regulation of the Hsp90 dynamics and stability by client recruiter cochaperones: protein structure network modeling
-
Blacklock K., Verkhivker G.M. Allosteric regulation of the Hsp90 dynamics and stability by client recruiter cochaperones: protein structure network modeling. PLoS ONE 2014, 9:e86547.
-
(2014)
PLoS ONE
, vol.9
, pp. e86547
-
-
Blacklock, K.1
Verkhivker, G.M.2
-
14
-
-
84901451274
-
The construction of an amino acid network for understanding protein structure and function
-
Yan W., Zhou J., Sun M., Chen J., Hu G., Shen B. The construction of an amino acid network for understanding protein structure and function. Amino Acids 2014, 46:1419-1439.
-
(2014)
Amino Acids
, vol.46
, pp. 1419-1439
-
-
Yan, W.1
Zhou, J.2
Sun, M.3
Chen, J.4
Hu, G.5
Shen, B.6
-
15
-
-
84878604130
-
The topology and dynamics of protein complexes: insights from intra-molecular network theory
-
Hu G., Zhou J., Yan W., Chen J., Shen B. The topology and dynamics of protein complexes: insights from intra-molecular network theory. Curr Protein Pept Sci 2013, 14:121-132.
-
(2013)
Curr Protein Pept Sci
, vol.14
, pp. 121-132
-
-
Hu, G.1
Zhou, J.2
Yan, W.3
Chen, J.4
Shen, B.5
-
16
-
-
84876274470
-
The emerging dynamic view of proteins: protein plasticity in allostery, evolution and self-assembly
-
Bastolla U., Porto M., Roman H.E. The emerging dynamic view of proteins: protein plasticity in allostery, evolution and self-assembly. Biochim Biophys Acta 2013, 1834:817-819.
-
(2013)
Biochim Biophys Acta
, vol.1834
, pp. 817-819
-
-
Bastolla, U.1
Porto, M.2
Roman, H.E.3
-
17
-
-
84876283834
-
Thermodynamics of allostery paves a way to allosteric drugs
-
Berezovsky I.N. Thermodynamics of allostery paves a way to allosteric drugs. Biochim Biophys Acta 2013, 1834:830-835.
-
(2013)
Biochim Biophys Acta
, vol.1834
, pp. 830-835
-
-
Berezovsky, I.N.1
-
18
-
-
36549043024
-
Intrinsic dynamics of enzymes in the unbound state and relation to allosteric regulation
-
Bahar I., Chennubhotla C., Tobi D. Intrinsic dynamics of enzymes in the unbound state and relation to allosteric regulation. Curr Opin Struct Biol 2007, 17:633-640.
-
(2007)
Curr Opin Struct Biol
, vol.17
, pp. 633-640
-
-
Bahar, I.1
Chennubhotla, C.2
Tobi, D.3
-
19
-
-
0033578690
-
Identification of side-chain clusters in protein structures by a graph spectral method
-
Kannan N., Vishveshwara S. Identification of side-chain clusters in protein structures by a graph spectral method. J Mol Biol 1999, 292:441-464.
-
(1999)
J Mol Biol
, vol.292
, pp. 441-464
-
-
Kannan, N.1
Vishveshwara, S.2
-
20
-
-
84893418609
-
Modules identification in protein structures: the topological and geometrical solutions
-
Tasdighian S., Di Paola L., De Ruvo M., Paci P., Santoni D., Palumbo P., Mei G., Di Venere A., Giuliani A. Modules identification in protein structures: the topological and geometrical solutions. J Chem Inf Model 2014, 54:159-168.
-
(2014)
J Chem Inf Model
, vol.54
, pp. 159-168
-
-
Tasdighian, S.1
Di Paola, L.2
De Ruvo, M.3
Paci, P.4
Santoni, D.5
Palumbo, P.6
Mei, G.7
Di Venere, A.8
Giuliani, A.9
-
21
-
-
14644396645
-
Functional cartography of complex metabolic networks
-
Guimerà R., Amaral L. Functional cartography of complex metabolic networks. Nature 2005, 433:895-900.
-
(2005)
Nature
, vol.433
, pp. 895-900
-
-
Guimerà, R.1
Amaral, L.2
-
22
-
-
84860714372
-
Shedding light on protein-ligand binding by graph theory: the topological nature of allostery
-
De Ruvo M., Giuliani A., Paci P., Santoni D. Shedding light on protein-ligand binding by graph theory: the topological nature of allostery. Biophys Chem 2012, 165-166:21-29.
-
(2012)
Biophys Chem
, pp. 21-29
-
-
De Ruvo, M.1
Giuliani, A.2
Paci, P.3
Santoni, D.4
-
23
-
-
41949141017
-
Proteins as networks: usefulness of graph theory in protein science
-
Krishnan A., Zbilut J.P., Tomita M., Giuliani A. Proteins as networks: usefulness of graph theory in protein science. Curr Protein Pept Sci 2008, 9:28-38.
-
(2008)
Curr Protein Pept Sci
, vol.9
, pp. 28-38
-
-
Krishnan, A.1
Zbilut, J.P.2
Tomita, M.3
Giuliani, A.4
-
24
-
-
79960189344
-
Dynamic allostery linkers are not merely flexible
-
Ma B., Tsai C.-J., Haliloğlu T., Nussinov R. Dynamic allostery linkers are not merely flexible. Structure 2011, 19:907-917.
-
(2011)
Structure
, vol.19
, pp. 907-917
-
-
Ma, B.1
Tsai, C.-J.2
Haliloğlu, T.3
Nussinov, R.4
-
25
-
-
6344219895
-
Is allostery an intrinsic property of all dynamic proteins?
-
Gunasekaran K., Ma B., Nussinov R. Is allostery an intrinsic property of all dynamic proteins?. Proteins 2004, 57:433-443.
-
(2004)
Proteins
, vol.57
, pp. 433-443
-
-
Gunasekaran, K.1
Ma, B.2
Nussinov, R.3
-
26
-
-
60649109828
-
Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms
-
Tsai C.-J., del Sol A., Nussinov R. Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms. Mol Biosyst 2009, 5:207-216.
-
(2009)
Mol Biosyst
, vol.5
, pp. 207-216
-
-
Tsai, C.-J.1
del Sol, A.2
Nussinov, R.3
-
27
-
-
84894246676
-
Multiple conformational selection and induced fit events take place in allosteric propagation
-
Nussinov R., Ma B., Tsai C.-J. Multiple conformational selection and induced fit events take place in allosteric propagation. Biophys Chem 2014, 186:22-30.
-
(2014)
Biophys Chem
, vol.186
, pp. 22-30
-
-
Nussinov, R.1
Ma, B.2
Tsai, C.-J.3
-
28
-
-
84866079682
-
Allosteric communication across the native and mutated KIT receptor tyrosine kinase
-
Laine E., Auclair C., Tchertanov L. Allosteric communication across the native and mutated KIT receptor tyrosine kinase. PLoS Comput Biol 2012, 8:e1002661.
-
(2012)
PLoS Comput Biol
, vol.8
, pp. e1002661
-
-
Laine, E.1
Auclair, C.2
Tchertanov, L.3
-
29
-
-
43949129091
-
Energy flow in proteins
-
Leitner D.M. Energy flow in proteins. Annu Rev Phys Chem 2008, 59:233-259.
-
(2008)
Annu Rev Phys Chem
, vol.59
, pp. 233-259
-
-
Leitner, D.M.1
-
30
-
-
62749124373
-
Residue network in protein native structure belongs to the universality class of a three-dimensional critical percolation cluster
-
Morita H., Takano M. Residue network in protein native structure belongs to the universality class of a three-dimensional critical percolation cluster. Phys Rev E 2009, 79:020901.
-
(2009)
Phys Rev E
, vol.79
, pp. 020901
-
-
Morita, H.1
Takano, M.2
-
31
-
-
70350031205
-
Understanding protein structure from a percolation perspective
-
Deb D., Vishveshwara S., Vishveshwara S. Understanding protein structure from a percolation perspective. Biophys J 2009, 97:1787-1794.
-
(2009)
Biophys J
, vol.97
, pp. 1787-1794
-
-
Deb, D.1
Vishveshwara, S.2
Vishveshwara, S.3
-
32
-
-
84898993517
-
The ensemble nature of allostery
-
Motlagh H.N., Wrabl J.O., Li J., Hilser V.J. The ensemble nature of allostery. Nature 2014, 508:331-339.
-
(2014)
Nature
, vol.508
, pp. 331-339
-
-
Motlagh, H.N.1
Wrabl, J.O.2
Li, J.3
Hilser, V.J.4
-
33
-
-
33745461893
-
Residues crucial for maintaining short paths in network communication mediate signaling in proteins
-
del Sol A., Fujihashi H., Amoros D., Nussinov R. Residues crucial for maintaining short paths in network communication mediate signaling in proteins. Mol Syst Biol 2006, 2.
-
(2006)
Mol Syst Biol
, vol.2
-
-
del Sol, A.1
Fujihashi, H.2
Amoros, D.3
Nussinov, R.4
-
34
-
-
68149157248
-
The origin of allosteric functional modulation: multiple pre-existing pathways
-
del Sol A., Tsai C.-J., Ma B., Nussinov R. The origin of allosteric functional modulation: multiple pre-existing pathways. Structure 2009, 17:1042-1050.
-
(2009)
Structure
, vol.17
, pp. 1042-1050
-
-
del Sol, A.1
Tsai, C.-J.2
Ma, B.3
Nussinov, R.4
-
36
-
-
84876266689
-
Allostery in disease and in drug discovery
-
Nussinov R., Tsai C.-J. Allostery in disease and in drug discovery. Cell 2013, 153:293-305.
-
(2013)
Cell
, vol.153
, pp. 293-305
-
-
Nussinov, R.1
Tsai, C.-J.2
-
37
-
-
84886914488
-
Perturbation centrality and turbine a novel centrality measure obtained using a versatile network dynamics tool
-
Szalay K.Z., Csermely P. Perturbation centrality and turbine a novel centrality measure obtained using a versatile network dynamics tool. PLoS ONE 2013, 8:e78059-e78111.
-
(2013)
PLoS ONE
, vol.8
, pp. e78059-e78111
-
-
Szalay, K.Z.1
Csermely, P.2
-
38
-
-
32344434479
-
The changing landscape of protein allostery
-
Swain J., Gierash L. The changing landscape of protein allostery. Curr Opin Struct Biol 2006, 16:102-108.
-
(2006)
Curr Opin Struct Biol
, vol.16
, pp. 102-108
-
-
Swain, J.1
Gierash, L.2
-
39
-
-
0037219686
-
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
-
Süel G.M., Lockless S.W., Wall M.A., Ranganathan R. Evolutionarily conserved networks of residues mediate allosteric communication in proteins. Nat Struct Biol 2003, 10:59-69.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 59-69
-
-
Süel, G.M.1
Lockless, S.W.2
Wall, M.A.3
Ranganathan, R.4
|