Live Imaging of Bioluminescent Leptospira interrogans in Mice Reveals Renal Colonization as a Stealth Escape from the Blood Defenses and Antibiotics

PLoS Neglected Tropical Diseases

Volumn 8, Issue 12, 2014, Pages

  Ratet, Gwenn ^a,b   Veyrier, Frédéric J ^a,b   Fanton d'Andon, Martine ^a,b   Kammerscheit, Xavier ^a,b,c   Nicola, Marie Anne ^a   Picardeau, Mathieu ^a   Boneca, Ivo G ^a,b   Werts, Catherine ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL DNA; BACTERIAL VECTOR; CIPROFLOXACIN; DOXYCYCLINE; LUCIFERIN; PENICILLIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL KINETICS; BACTERIAL LOAD; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CONJUGATION; BIOLUMINESCENCE; BLOOD ANALYSIS; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; FLUORESCENCE IMAGING; GENE EXPRESSION; KIDNEY INFECTION; LEPTOSPIRA BIFLEXA; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LUCIFERASE ASSAY; MOUSE; MUTAGENESIS; NONHUMAN; PERITONEAL CAVITY; PLASMID; REAL TIME POLYMERASE CHAIN REACTION; SEPTICEMIA; SURVIVAL; TRANSPOSON MUTAGENESIS; URINALYSIS; ANIMAL; BLOOD; C57BL MOUSE; GENETICS; ISOLATION AND PURIFICATION; KIDNEY DISEASE; LUMINESCENCE; MICROBIOLOGY; PROCEDURES; SEPSIS;

ANIMALS; FEMALE; KIDNEY DISEASES; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED C57BL; OPTICAL IMAGING; SEPSIS;

EID: 84928250598     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003359     Document Type: Article

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