A methylated phosphate group and four amide-linked acyl chains in Leptospira interrogans lipid A: The membrane anchor of an unusual lipopolysaccharide that activates TLR2

Journal of Biological Chemistry

Volumn 279, Issue 24, 2004, Pages 25420-25429

  Que Gewirth, Nanette L S ^a   Ribeiro, Anthony A ^a   Kalb, Suzanne R ^b   Cotter, Robert J ^b   Bulach, Dieter M ^c   Adler, Ben ^c   Saint Girons, Isabelle ^d   Werts, Catherine ^d   Raetz, Christian R H ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MONASH UNIVERSITY   (Australia)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; CHROMATOGRAPHIC ANALYSIS; DESORPTION; ESCHERICHIA COLI; LASER APPLICATIONS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATES; POLYSACCHARIDES;

AMIDE-LINKED ACYL CHAINS; DISTAL RESIDUES; LIPOPOLYSACCHARIDES (LPS);

BIOCHEMISTRY;

2,3 DIAMINO 2,3 DIDEOXY DEXTRO GLUCOPYRANOSE; 3 HYDROXYLAURATE; 3 HYDROXYPALMITATE; AMIDE; DISACCHARIDE; DODECYL SULFATE SODIUM; GLUCOPYRANOSIDE; LAURIC ACID; LIPID A; LIPOPOLYSACCHARIDE; PALMITIC ACID; PHOSPHATE; SODIUM HYDROXIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ACYLATION; ANIMAL CELL; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BACTERIAL VIRULENCE; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; HYDROLYSIS; LEPTOSPIRA INTERROGANS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHYLATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR UPREGULATION; THIN LAYER CHROMATOGRAPHY;

ANIMALS; HUMANS; HYDROLYSIS; LEPTOSPIRA INTERROGANS; LIPID A; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE GLYCOPROTEINS; MICE; RECEPTORS, CELL SURFACE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LEPTOSPIRA; LEPTOSPIRA INTERROGANS; LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE; LEPTOSPIRA INTERROGANS SEROVAR POMONA;

EID: 2942595715     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400598200     Document Type: Article

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