-
1
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J. & King M. C. Genetic heterogeneity in human disease. Cell 141, 210-217 (2010
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
2
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander E. S. & Schork N. J. Genetic dissection of complex traits. Science 265, 2037-2048 (1994
-
(1994)
Science
, vol.265
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
3
-
-
0033062050
-
Genetic linkage analysis
-
Pulst S. M. Genetic linkage analysis. Arch. Neurol. 56, 667-672 (1999
-
(1999)
Arch. Neurol
, vol.56
, pp. 667-672
-
-
Pulst, S.M.1
-
4
-
-
55449120805
-
Genetic mapping in human disease
-
Altshuler D., Daly M. J. & Lander E. S. Genetic mapping in human disease. Science 322, 881-888 (2008
-
(2008)
Science
, vol.322
, pp. 881-888
-
-
Altshuler, D.1
Daly, M.J.2
Lander, E.S.3
-
5
-
-
84055193413
-
Linkage analysis in the next-generation sequencing era
-
Bailey-Wilson J. E. & Wilson A. F. Linkage analysis in the next-generation sequencing era. Hum. Hered. 72, 228-236 (2011
-
(2011)
Hum. Hered
, vol.72
, pp. 228-236
-
-
Bailey-Wilson, J.E.1
Wilson, A.F.2
-
9
-
-
0002781574
-
Versuche über pflanzen-hybriden
-
in German
-
Mendel G. J. Versuche über Pflanzen-Hybriden. Verh. Naturforsch. Ver. Brünn 4, 3-47 (in German) (1866
-
(1866)
Verh Naturforsch Ver. Brünn
, vol.4
, pp. 3-47
-
-
Mendel, G.J.1
-
10
-
-
84880292975
-
Mutations in KARS encoding lysyl-tRNA synthetase cause autosomal-recessive nonsyndromic hearing impairment DFNB89
-
Santos-Cortez R. L., et al. Mutations in KARS encoding lysyl-tRNA synthetase cause autosomal-recessive nonsyndromic hearing impairment DFNB89. Am. J. Hum. Genet. 93, 132-140 (2013
-
(2013)
Am. J. Hum. Genet
, vol.93
, pp. 132-140
-
-
Santos-Cortez, R.L.1
-
11
-
-
0007652405
-
Gen und ausseneigenschaft (untersuchungen an drosophila) IZ
-
in German
-
Goldschmidt R. Gen und Ausseneigenschaft (Untersuchungen an Drosophila) I. Z. Indukt Abstamm Vererbungsl 69, 38-69 (in German) (1935
-
(1935)
Indukt Abstamm Vererbungsl
, vol.69
, pp. 38-69
-
-
Goldschmidt, R.1
-
12
-
-
0038763500
-
Phenocopies
-
Goldschmidt R. B. Phenocopies. Sci. Am. 181, 46-49 (1949
-
(1949)
Sci. Am
, vol.181
, pp. 46-49
-
-
Goldschmidt, R.B.1
-
13
-
-
33646188852
-
Family-based designs in the age of large-scale gene-association studies
-
Laird N. M. & Lange C. Family-based designs in the age of large-scale gene-association studies. Nature Rev. Genet. 7, 385-394 (2006
-
(2006)
Nature Rev. Genet
, vol.7
, pp. 385-394
-
-
Laird, N.M.1
Lange, C.2
-
14
-
-
40749151849
-
Family-based methods for linkage and association analysis
-
Laird N. M. & Lange C. Family-based methods for linkage and association analysis. Adv. Genet. 60, 219-252 (2008
-
(2008)
Adv. Genet
, vol.60
, pp. 219-252
-
-
Laird, N.M.1
Lange, C.2
-
15
-
-
79959378465
-
Family-based designs for genome-wide association studies
-
Ott J., Kamatani Y. & Lathrop M. Family-based designs for genome-wide association studies. Nature Rev. Genet. 12, 465-474 (2011
-
(2011)
Nature Rev. Genet
, vol.12
, pp. 465-474
-
-
Ott, J.1
Kamatani, Y.2
Lathrop, M.3
-
16
-
-
0036137130
-
Linkage disequilibrium and the mapping of complex human traits
-
Weiss K. M. & Clark A. G. Linkage disequilibrium and the mapping of complex human traits. Trends Genet. 18, 19-24 (2002
-
(2002)
Trends Genet
, vol.18
, pp. 19-24
-
-
Weiss, K.M.1
Clark, A.G.2
-
17
-
-
80052465702
-
Multiple phenotypes in genome-wide genetic mapping studies
-
Ott J. & Wang J. Multiple phenotypes in genome-wide genetic mapping studies. Protein Cell 2, 519-522 (2011
-
(2011)
Protein Cell
, vol.2
, pp. 519-522
-
-
Ott, J.1
Wang, J.2
-
18
-
-
0031466983
-
From genotypes to genes: Doubling the sample size
-
Sasieni P. D. From genotypes to genes: doubling the sample size. Biometrics 53, 1253-1261 (1997
-
(1997)
Biometrics
, vol.53
, pp. 1253-1261
-
-
Sasieni, P.D.1
-
19
-
-
0023235253
-
Haplotype relative risks: An easy reliable way to construct a proper control sample for risk calculations
-
Falk C. T. & Rubinstein P. Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann. Hum. Genet. 51, 227-233 (1987
-
(1987)
Ann. Hum. Genet
, vol.51
, pp. 227-233
-
-
Falk, C.T.1
Rubinstein, P.2
-
20
-
-
0026494911
-
A haplotype-based "haplotype relative risk" approach to detecting allelic associations
-
Terwilliger J. D. & Ott J. A haplotype-based "haplotype relative risk" approach to detecting allelic associations. Hum. Hered. 42, 337-346 (1992
-
(1992)
Hum. Hered
, vol.42
, pp. 337-346
-
-
Terwilliger, J.D.1
Ott, J.2
-
21
-
-
0024536523
-
Statistical properties of the haplotype relative risk
-
Ott J. Statistical properties of the haplotype relative risk. Genet. Epidemiol. 6, 127-130 (1989
-
(1989)
Genet. Epidemiol
, vol.6
, pp. 127-130
-
-
Ott, J.1
-
22
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM
-
Spielman R. S., McGinnis R. E. & Ewens W. J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. 52, 506-516 (1993
-
(1993)
Am. J. Hum. Genet
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
23
-
-
84891831893
-
Rare-variant extensions of the transmission disequilibrium test: Application to autism exome sequence data
-
He Z., et al. Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data. Am. J. Hum. Genet. 94, 33-46 (2014
-
(2014)
Am. J. Hum. Genet
, vol.94
, pp. 33-46
-
-
He, Z.1
-
24
-
-
84872389630
-
Rare variant analysis for family-based design
-
De, G., Yip W. K., Ionita-Laza I. & Laird N. Rare variant analysis for family-based design. PLoS ONE 8, e48495 (2013
-
(2013)
Plos One
, vol.8
, pp. e48495
-
-
Yip, W.K.1
Ionita-Laza, I.2
Laird, N.3
-
25
-
-
50949095168
-
Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
-
Li B. & Leal S. M. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am. J. Hum. Genet. 83, 311-321 (2008
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 311-321
-
-
Li, B.1
Leal, S.M.2
-
26
-
-
84904006087
-
Rare-variant association analysis: Study designs and statistical tests
-
Lee S., Abecasis G. R., Boehnke M. & Lin X. Rare-variant association analysis: study designs and statistical tests. Am. J. Hum. Genet. 95, 5-23 (2014
-
(2014)
Am. J. Hum. Genet
, vol.95
, pp. 5-23
-
-
Lee, S.1
Abecasis, G.R.2
Boehnke, M.3
Lin, X.4
-
27
-
-
84899476119
-
Guidelines for investigating causality of sequence variants in human disease
-
MacArthur D. G., et al. Guidelines for investigating causality of sequence variants in human disease. Nature 508, 469-476 (2014
-
(2014)
Nature
, vol.508
, pp. 469-476
-
-
MacArthur, D.G.1
-
28
-
-
51149186884
-
Change of linkage in poultry with age
-
Haldane J. B. S. & Crew F. A. E. Change of linkage in poultry with age. Nature 115, 641 (1925
-
(1925)
Nature
, vol.115
, pp. 641
-
-
Haldane, J.B.S.1
Crew, F.A.E.2
-
29
-
-
84984084531
-
Male and female recombination fractions for the nail-patella:ABO linkage in man
-
Renwick J. H. & Schulze J. Male and female recombination fractions for the nail-patella:ABO linkage in man. Ann. Hum. Genet. 28, 37992 (1965
-
(1965)
Ann. Hum. Genet
, vol.28
, pp. 37992
-
-
Renwick, J.H.1
Schulze, J.2
-
30
-
-
0017236514
-
Age trends in human chiasma frequencies and recombination fractions ii method for analyzing recombination fractions and applications to the abo:nail-patella linkage
-
Elston R. C., Lange E. & Namboodiri K. K. Age trends in human chiasma frequencies and recombination fractions. II. Method for analyzing recombination fractions and applications to the ABO:nail-patella linkage. Am. J. Hum. Genet. 28, 69-76 (1976
-
(1976)
Am. J. Hum. Genet
, vol.28
, pp. 69-76
-
-
Elston, R.C.1
Lange, E.2
Namboodiri, K.K.3
-
31
-
-
0026514890
-
A genetic linkage map of human chromosome 21: Analysis of recombination as a function of sex and age
-
Tanzi R. E., et al. A genetic linkage map of human chromosome 21: analysis of recombination as a function of sex and age. Am. J. Hum. Genet. 50, 551-558 (1992
-
(1992)
Am. J. Hum. Genet
, vol.50
, pp. 551-558
-
-
Tanzi, R.E.1
-
32
-
-
0036077159
-
Absence of age effect on meiotic recombination between human X and y chromosomes
-
Shi Q., et al. Absence of age effect on meiotic recombination between human X and Y chromosomes. Am. J. Hum. Genet. 71, 254-261 (2002
-
(2002)
Am. J. Hum. Genet
, vol.71
, pp. 254-261
-
-
Shi, Q.1
-
33
-
-
33750525282
-
Intrafamilial phenotypic and genetic heterogeneity of dystonia
-
Kostic V. S., et al. Intrafamilial phenotypic and genetic heterogeneity of dystonia. J. Neurol. Sci. 250, 92-96 (2006
-
(2006)
J. Neurol. Sci
, vol.250
, pp. 92-96
-
-
Kostic, V.S.1
-
34
-
-
0021028244
-
A polymorphic DNA marker genetically linked to Huntington"s disease
-
Gusella J. F., et al. A polymorphic DNA marker genetically linked to Huntington"s disease. Nature 306, 234-238 (1983
-
(1983)
Nature
, vol.306
, pp. 234-238
-
-
Gusella, J.F.1
-
35
-
-
84858074593
-
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
-
Lee J. M., et al. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology 78, 690-695 (2012
-
(2012)
Neurology
, vol.78
, pp. 690-695
-
-
Lee, J.M.1
-
36
-
-
0020299140
-
Epistatic association and linkage analysis in human families
-
Ott J. & Falk C. T. Epistatic association and linkage analysis in human families. Hum. Genet. 62, 296-300 (1982
-
(1982)
Hum. Genet
, vol.62
, pp. 296-300
-
-
Ott, J.1
Falk, C.T.2
-
37
-
-
0003577580
-
-
eds Gershon E. S. & Cloninger C. R. American Psychiatric Press
-
Ott J. in Genetic Approaches to Mental Disorders (eds Gershon E. S. & Cloninger C. R.) 63-75 (American Psychiatric Press 1994
-
(1994)
Genetic Approaches to Mental Disorders
, pp. 63-75
-
-
Ott, J.1
-
38
-
-
25944453426
-
A computer program for the processing of linkage data from large pedigrees
-
Renwick J. H. & Schulze J. A computer program for the processing of linkage data from large pedigrees. Excerpta Med. Int. Congr Ser. 32, E145 (1961
-
(1961)
Excerpta Med. Int. Congr ser
, vol.32
, pp. E145
-
-
Renwick, J.H.1
Schulze, J.2
-
39
-
-
0015183542
-
A general model for the genetic analysis of pedigree data
-
Elston R. C. & Stewart J. A general model for the genetic analysis of pedigree data. Hum. Hered. 21, 523-542 (1971
-
(1971)
Hum. Hered
, vol.21
, pp. 523-542
-
-
Elston, R.C.1
Stewart, J.2
-
40
-
-
0026611939
-
The Elston-Stewart algorithm for continuous genotypes and environmental factors
-
Elston R. C., George V. T. & Severtson F. The Elston-Stewart algorithm for continuous genotypes and environmental factors. Hum. Hered. 42, 16-27 (1992
-
(1992)
Hum. Hered
, vol.42
, pp. 16-27
-
-
Elston, R.C.1
George, V.T.2
Severtson, F.3
-
41
-
-
0016302483
-
Estimation of the recombination fraction in human pedigrees: Efficient computation of the likelihood for human linkage studies
-
Ott J. Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am. J. Hum. Genet. 26, 588-597 (1974
-
(1974)
Am. J. Hum. Genet
, vol.26
, pp. 588-597
-
-
Ott, J.1
-
42
-
-
84893802270
-
A statistical framework to guide sequencing choices in pedigrees
-
Cheung C. Y., Marchani Blue E. & Wijsman E. M. A statistical framework to guide sequencing choices in pedigrees. Am. J. Hum. Genet. 94, 257-267 (2014
-
(2014)
Am. J. Hum. Genet
, vol.94
, pp. 257-267
-
-
Cheung, C.Y.1
Marchani Blue, E.2
Wijsman, E.M.3
-
43
-
-
0000803318
-
Construction of multilocus genetic linkage maps in humans
-
Lander E. S. & Green P. Construction of multilocus genetic linkage maps in humans. Proc. Natl Acad. Sci. USA 84, 2363-2367 (1987
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 2363-2367
-
-
Lander, E.S.1
Green, P.2
-
46
-
-
0029886532
-
Parametric and nonparametric linkage analysis: A unified multipoint approach
-
Kruglyak L., Daly M. J., Reeve-Daly M. P. & Lander E. S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am. J. Hum. Genet. 58, 1347-1363 (1996
-
(1996)
Am. J. Hum. Genet
, vol.58
, pp. 1347-1363
-
-
Kruglyak, L.1
Daly, M.J.2
Reeve-Daly, M.P.3
Lander, E.S.4
-
47
-
-
0036338150
-
Merlin -rapid analysis of dense genetic maps using sparse gene flow trees
-
Abecasis G. R., Cherny S. S., Cookson W. O. & Cardon L. R. MERLIN -rapid analysis of dense genetic maps using sparse gene flow trees. Nature Genet. 30, 97-101 (2002
-
(2002)
Nature Genet
, vol.30
, pp. 97-101
-
-
Abecasis, G.R.1
Cherny, S.S.2
Cookson, W.O.3
Cardon, L.R.4
-
48
-
-
34548292504
-
Plink: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S., et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007
-
(2007)
Am. J. Hum. Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
49
-
-
79960405019
-
The variant call format and VCFtools
-
Danecek P., et al. The variant call format and VCFtools. Bioinformatics 27, 2156-2158 (2011
-
(2011)
Bioinformatics
, vol.27
, pp. 2156-2158
-
-
Danecek, P.1
-
50
-
-
84899859455
-
Variant association tools for quality control and analysis of large-scale sequence and genotyping array data
-
Wang G. T., Peng B. & Leal S. M. Variant association tools for quality control and analysis of large-scale sequence and genotyping array data. Am. J. Hum. Genet. 94, 770-783 (2014
-
(2014)
Am. J. Hum. Genet
, vol.94
, pp. 770-783
-
-
Wang, G.T.1
Peng, B.2
Leal, S.M.3
-
51
-
-
84928205949
-
Collapsed haplotype pattern method for linkage analysis of next generation sequence data
-
(in the press
-
Wang G. T., Zhang D., Li B., Dai H. & Leal S. M. Collapsed haplotype pattern method for linkage analysis of next generation sequence data. Eur. J. Hum. Genet. (in the press
-
Eur. J. Hum. Genet
-
-
Wang, G.T.1
Zhang, D.2
Li, B.3
Dai, H.4
Leal, S.M.5
-
52
-
-
0026528757
-
Gibbs sampling approach to linkage analysis
-
Thomas D. C. & Cortessis V. A. Gibbs sampling approach to linkage analysis. Hum. Hered. 42, 63-76 (1992
-
(1992)
Hum. Hered
, vol.42
, pp. 63-76
-
-
Thomas, D.C.1
Cortessis, V.A.2
-
53
-
-
0030833349
-
Markov chain Monte Carlo segregation and linkage analysis for oligogenic models
-
Heath S. C. Markov chain Monte Carlo segregation and linkage analysis for oligogenic models. Am. J. Hum. Genet. 61, 748-760 (1997
-
(1997)
Am. J. Hum. Genet
, vol.61
, pp. 748-760
-
-
Heath, S.C.1
-
54
-
-
0035741831
-
Multipoint estimation of identity-by descent probabilities at arbitrary positions among marker loci on general pedigrees
-
Sobel E., Sengul H. & Weeks D. E. Multipoint estimation of identity-by descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum. Hered. 52, 121-131 (2001
-
(2001)
Hum. Hered
, vol.52
, pp. 121-131
-
-
Sobel, E.1
Sengul, H.2
Weeks, D.E.3
-
55
-
-
0000877874
-
The detection of autosomal linkage in data which consist of pairs of brothers and sisters of unspecified parentage
-
Penrose L. S. The detection of autosomal linkage in data which consist of pairs of brothers and sisters of unspecified parentage. Ann. Eugen. 6, 133-138 (1935
-
(1935)
Ann. Eugen
, vol.6
, pp. 133-138
-
-
Penrose, L.S.1
-
56
-
-
0028030120
-
Two-locus disease models with two marker loci: The power of affected-sib-pair tests
-
Knapp M., Seuchter S. A. & Baur M. P. Two-locus disease models with two marker loci: the power of affected-sib-pair tests. Am. J. Hum. Genet. 55, 1030-1041 (1994
-
(1994)
Am. J. Hum. Genet
, vol.55
, pp. 1030-1041
-
-
Knapp, M.1
Seuchter, S.A.2
Baur, M.P.3
-
57
-
-
0028301661
-
A class of tests for linkage using affected pedigree members
-
Whittemore A. S. & Halpern J. A class of tests for linkage using affected pedigree members. Biometrics 50, 118-127 (1994
-
(1994)
Biometrics
, vol.50
, pp. 118-127
-
-
Whittemore, A.S.1
Halpern, J.2
-
58
-
-
77949739613
-
A likelihood-based trait-model-free approach for linkage detection of binary trait
-
Basu S., Stephens M., Pankow J. S. & Thompson E. A. A likelihood-based trait-model-free approach for linkage detection of binary trait. Biometrics 66, 205-213 (2010
-
(2010)
Biometrics
, vol.66
, pp. 205-213
-
-
Basu, S.1
Stephens, M.2
Pankow, J.S.3
Thompson, E.A.4
-
59
-
-
0028123781
-
Linkage analysis in nuclear families 2: Relationship between affected sib-pair tests and lod score analysis
-
Knapp M., Seuchter S. A. & Baur M. P. Linkage analysis in nuclear families. 2: relationship between affected sib-pair tests and lod score analysis. Hum. Hered. 44, 44-51 (1994
-
(1994)
Hum. Hered
, vol.44
, pp. 44-51
-
-
Knapp, M.1
Seuchter, S.A.2
Baur, M.P.3
-
60
-
-
84865064823
-
Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major loci
-
Su, M. & Thompson E. A. Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major loci. Genet. Epidemiol. 36, 602-611 (2012
-
(2012)
Genet. Epidemiol
, vol.36
, pp. 602-611
-
-
Su, M.1
Thompson, E.A.2
-
61
-
-
4043126045
-
Efficient two-trait-locus linkage analysis through program optimization and parallelization: Application to hypercholesterolemia
-
Dietter J., et al. Efficient two-trait-locus linkage analysis through program optimization and parallelization: application to hypercholesterolemia. Eur. J. Hum. Genet. 12, 542-550 (2004
-
(2004)
Eur. J. Hum. Genet
, vol.12
, pp. 542-550
-
-
Dietter, J.1
-
62
-
-
84890145395
-
Digenic inheritance in medical genetics
-
Schaffer A. A. Digenic inheritance in medical genetics. J. Med. Genet. 50, 641-652 (2013
-
(2013)
J. Med. Genet
, vol.50
, pp. 641-652
-
-
Schaffer, A.A.1
-
63
-
-
0027430716
-
Two-trait-locus linkage analysis: A powerful strategy for mapping complex genetic traits
-
Schork N. J., Boehnke M., Terwilliger J. D. & Ott J. Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am. J. Hum. Genet. 53, 1127-1136 (1993
-
(1993)
Am. J. Hum. Genet
, vol.53
, pp. 1127-1136
-
-
Schork, N.J.1
Boehnke, M.2
Terwilliger, J.D.3
Ott, J.4
-
64
-
-
0028108808
-
Two-locus versus one-locus LODs for complex traits
-
Sham P. C., MacLean C. J. & Kendler K. S. Two-locus versus one-locus LODs for complex traits. Am. J. Hum. Genet. 55, 855-858 (1994
-
(1994)
Am. J. Hum. Genet
, vol.55
, pp. 855-858
-
-
Sham, P.C.1
MacLean, C.J.2
Kendler, K.S.3
-
66
-
-
77958091897
-
Reconciling the analysis of ibd and ibs in complex trait studies
-
Powell J. E., Visscher P. M. & Goddard M. E. Reconciling the analysis of IBD and IBS in complex trait studies. Nature Rev. Genet. 11, 800-805 (2010
-
(2010)
Nature Rev. Genet
, vol.11
, pp. 800-805
-
-
Powell, J.E.1
Visscher, P.M.2
Goddard, M.E.3
-
67
-
-
84881094790
-
Filtering for compound heterozygous sequence variants in non-consanguineous pedigrees
-
Kamphans T., et al. Filtering for compound heterozygous sequence variants in non-consanguineous pedigrees. PLoS ONE 8, e70151 (2013
-
(2013)
Plos One
, vol.8
, pp. e70151
-
-
Kamphans, T.1
-
68
-
-
0027503622
-
Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats
-
Dubay C., et al. Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. Nature Genet. 3, 354-357 (1993
-
(1993)
Nature Genet
, vol.3
, pp. 354-357
-
-
Dubay, C.1
-
69
-
-
77954781283
-
Univariate and bivariate linkage analysis identifies pleiotropic loci underlying lipid levels and type 2 diabetes risk
-
Hasstedt S. J., Hanis C. L. & Elbein S. C. Univariate and bivariate linkage analysis identifies pleiotropic loci underlying lipid levels and type 2 diabetes risk. Ann. Hum. Genet. 74, 308-315 (2010
-
(2010)
Ann. Hum. Genet
, vol.74
, pp. 308-315
-
-
Hasstedt, S.J.1
Hanis, C.L.2
Elbein, S.C.3
-
70
-
-
0022505001
-
An approach to the multivariate analysis of high-density-lipoprotein cholesterol in a large kindred: The bogalusa heart study
-
Amos C. I., et al. An approach to the multivariate analysis of high-density-lipoprotein cholesterol in a large kindred: the Bogalusa Heart Study. Genet. Epidemiol. 3, 255-267 (1986
-
(1986)
Genet. Epidemiol
, vol.3
, pp. 255-267
-
-
Amos, C.I.1
-
71
-
-
0032231766
-
Multiple phenotype modeling in gene-mapping studies of quantitative traits: Power advantages
-
Allison D. B., et al. Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages. Am. J. Hum. Genet. 63, 1190-1201 (1998
-
(1998)
Am. J. Hum. Genet
, vol.63
, pp. 1190-1201
-
-
Allison, D.B.1
-
72
-
-
0033032420
-
A principal-components approach based on heritability for combining phenotype information
-
Ott J. & Rabinowitz D. A principal-components approach based on heritability for combining phenotype information. Hum. Hered. 49, 106-111 (1999
-
(1999)
Hum. Hered
, vol.49
, pp. 106-111
-
-
Ott, J.1
Rabinowitz, D.2
-
73
-
-
84876843992
-
Analysis of multiple phenotypes in genome-wide genetic mapping studies
-
Suo C., et al. Analysis of multiple phenotypes in genome-wide genetic mapping studies. BMC Bioinformatics 14, 151 (2013
-
(2013)
BMC Bioinformatics
, vol.14
, Issue.151
-
-
Suo, C.1
-
74
-
-
57349189085
-
Multivariate genomewide linkage scan of neurocognitive traits and adhd symptoms: Suggestive linkage to 3q13
-
Doyle A. E., et al. Multivariate genomewide linkage scan of neurocognitive traits and ADHD symptoms: suggestive linkage to 3q13. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 147B, 1399-1411 (2008
-
(2008)
Am. J. Med. Genet. B. Neuropsychiatr. Genet
, vol.147 B
, pp. 1399-1411
-
-
Doyle, A.E.1
-
75
-
-
0027942323
-
Genome screening by searching for shared segments: Mapping a gene for benign recurrent intrahepatic cholestasis
-
Houwen R. H., et al. Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis. Nature Genet. 8, 380-386 (1994
-
(1994)
Nature Genet
, vol.8
, pp. 380-386
-
-
Houwen, R.H.1
-
77
-
-
84863556835
-
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
-
Tennessen J. A., et al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 337, 64-69 (2012
-
(2012)
Science
, vol.337
, pp. 64-69
-
-
Tennessen, J.A.1
-
78
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Genomes Project C., et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Genomes Project, C.1
-
79
-
-
80052833627
-
Reducing the exome search space for mendelian diseases using genetic linkage analysis of exome genotypes
-
Smith K. R., et al. Reducing the exome search space for Mendelian diseases using genetic linkage analysis of exome genotypes. Genome Biol. 12, R85 (2011
-
(2011)
Genome Biol
, vol.12
, pp. R85
-
-
Smith, K.R.1
-
80
-
-
84868138663
-
A likelihood-based framework for variant calling and de novo mutation detection in families
-
Li B., et al. A likelihood-based framework for variant calling and de novo mutation detection in families. PLoS Genet. 8, e1002944 (2012
-
(2012)
Plos Genet
, vol.8
, pp. e1002944
-
-
Li, B.1
-
81
-
-
77956295988
-
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
-
McKenna A., et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20, 1297-1303 (2010
-
(2010)
Genome Res
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
-
82
-
-
84969213492
-
Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls
-
Bentley D., et al. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 447, 661-678 (2007
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
Bentley, D.1
-
83
-
-
0027514896
-
Molecular and statistical approaches to the detection and correction of errors in genotype databases
-
Brzustowicz L. M., et al. Molecular and statistical approaches to the detection and correction of errors in genotype databases. Am. J. Hum. Genet. 53, 1137-1145 (1993
-
(1993)
Am. J. Hum. Genet
, vol.53
, pp. 1137-1145
-
-
Brzustowicz, L.M.1
-
84
-
-
0027406460
-
Detecting marker inconsistencies in human gene mapping
-
Ott J. Detecting marker inconsistencies in human gene mapping. Hum. Hered. 43, 25-30 (1993
-
(1993)
Hum. Hered
, vol.43
, pp. 25-30
-
-
Ott, J.1
-
85
-
-
0033643184
-
An analytic solution to single nucleotide polymorphism error-detection rates in nuclear families: Implications for study design
-
Gordon D., Leal S. M., Heath S. C. & Ott J. An analytic solution to single nucleotide polymorphism error-detection rates in nuclear families: implications for study design. Pac. Symp. Biocomput. 2, 663-674 (2000
-
(2000)
Pac. Symp. Biocomput
, vol.2
, pp. 663-674
-
-
Gordon, D.1
Leal, S.M.2
Heath, S.C.3
Ott, J.4
-
86
-
-
84899045235
-
Detection of Mendelian consistent genotyping errors in pedigrees
-
Cheung C. Y., Thompson E. A. & Wijsman E. M. Detection of Mendelian consistent genotyping errors in pedigrees. Genet. Epidemiol. 38, 291-299 (2014
-
(2014)
Genet. Epidemiol
, vol.38
, pp. 291-299
-
-
Cheung, C.Y.1
Thompson, E.A.2
Wijsman, E.M.3
-
87
-
-
0036152708
-
Nonpaternity in linkage studies of extremely discordant sib pairs
-
Neale M. C., Neale B. M. & Sullivan P. F. Nonpaternity in linkage studies of extremely discordant sib pairs. Am. J. Hum. Genet. 70, 526-529 (2002
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 526-529
-
-
Neale, M.C.1
Neale, B.M.2
Sullivan, P.F.3
-
88
-
-
0036152559
-
Hlods remain powerful tools for detection of linkage in the presence of genetic heterogeneity
-
Hodge S. E., Vieland V. J. & Greenberg D. A. HLODs remain powerful tools for detection of linkage in the presence of genetic heterogeneity. Am. J. Hum. Genet. 70, 556-559 (2002
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 556-559
-
-
Hodge, S.E.1
Vieland, V.J.2
Greenberg, D.A.3
-
89
-
-
84901316993
-
Adenylate cyclase 1 (adcy1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish
-
Santos-Cortez R. L., et al. Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish. Hum. Mol. Genet. 23, 3289-3298 (2014
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. 3289-3298
-
-
Santos-Cortez, R.L.1
-
90
-
-
84880909923
-
Combined linkage analysis and exome sequencing identifies novel genes for familial goiter
-
Yan J., et al. Combined linkage analysis and exome sequencing identifies novel genes for familial goiter. J. Hum. Genet. 58, 366-377 (2013
-
(2013)
J. Hum. Genet
, vol.58
, pp. 366-377
-
-
Yan, J.1
-
91
-
-
84859425383
-
Klhl3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
-
Louis-Dit-Picard H., et al. KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nature Genet. 44, 456-460 (2012
-
(2012)
Nature Genet
, vol.44
, pp. 456-460
-
-
Louis-Dit-Picard, H.1
-
92
-
-
24144493144
-
Easylinkage-Plus -automated linkage analyses using large-scale SNP data
-
Hoffmann K. & Lindner T. H. easyLINKAGE-Plus -automated linkage analyses using large-scale SNP data. Bioinformatics 21, 3565-3567 (2005
-
(2005)
Bioinformatics
, vol.21
, pp. 3565-3567
-
-
Hoffmann, K.1
Lindner, T.H.2
-
93
-
-
0021850103
-
Multilocus linkage analysis in humans: Detection of linkage and estimation of recombination
-
Lathrop G. M., Lalouel J. M., Julier C. & Ott J. Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am. J. Hum. Genet. 37, 482-498 (1985
-
(1985)
Am. J. Hum. Genet
, vol.37
, pp. 482-498
-
-
Lathrop, G.M.1
Lalouel, J.M.2
Julier, C.3
Ott, J.4
-
94
-
-
0031443227
-
MCMC segregation and linkage analysis
-
Heath S. C., Snow G. L., Thompson E. A., Tseng C. & Wijsman E. M. MCMC segregation and linkage analysis. Genet. Epidemiol. 14, 1011-1016 (1997
-
(1997)
Genet. Epidemiol
, vol.14
, pp. 1011-1016
-
-
Heath, S.C.1
Snow, G.L.2
Thompson, E.A.3
Tseng, C.4
Wijsman, E.M.5
-
95
-
-
84878881153
-
Mendel: The Swiss army knife of genetic analysis programs
-
Lange K., et al. Mendel: the Swiss army knife of genetic analysis programs. Bioinformatics 29, 1568-1570 (2013
-
(2013)
Bioinformatics
, vol.29
, pp. 1568-1570
-
-
Lange, K.1
-
96
-
-
0024190141
-
Programs for pedigree analysis: Mendel fisher and dgene
-
Lange K., Weeks D. & Boehnke M. Programs for pedigree analysis: MENDEL FISHER and dGENE. Genet. Epidemiol. 5, 471-472 (1988
-
(1988)
Genet. Epidemiol
, vol.5
, pp. 471-472
-
-
Lange, K.1
Weeks, D.2
Boehnke, M.3
-
97
-
-
79960139528
-
Coordinated conditional simulation with slink and sup of many markers linked or associated to a trait in large pedigrees
-
Schaffer A. A., Lemire M., Ott J., Lathrop G. M. & Weeks D. E. Coordinated conditional simulation with SLINK and SUP of many markers linked or associated to a trait in large pedigrees. Hum. Hered. 71, 126-134 (2011
-
(2011)
Hum. Hered
, vol.71
, pp. 126-134
-
-
Schaffer, A.A.1
Lemire, M.2
Ott, J.3
Lathrop, G.M.4
Weeks, D.E.5
-
98
-
-
0032231941
-
Ped check a program for identification of genotype incompatibilities in linkage analysis
-
O"Connell J. R. & Weeks D. E. PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am. J. Hum. Genet. 63, 259-266 (1998
-
(1998)
Am. J. Hum. Genet
, vol.63
, pp. 259-266
-
-
O'Connell, J.R.1
Weeks, D.E.2
-
99
-
-
84894283534
-
Pseudomarker 2.0: Efficient computation of likelihoods using nomad
-
Gertz E. M., et al. PSEUDOMARKER 2.0: efficient computation of likelihoods using NOMAD. BMC Bioinformatics 15, 47 (2014
-
(2014)
BMC Bioinformatics
, vol.15
, Issue.47
-
-
Gertz, E.M.1
-
100
-
-
0038558013
-
Exact genetic linkage computations for general pedigrees
-
Fishelson M. & Geiger D. Exact genetic linkage computations for general pedigrees. Bioinformatics 18, S189-S198 (2002
-
(2002)
Bioinformatics
, vol.18
, pp. S189-S198
-
-
Fishelson, M.1
Geiger, D.2
-
101
-
-
0028877463
-
Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
-
Lander E. & Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet. 11, 241-247 (1995
-
(1995)
Nature Genet
, vol.11
, pp. 241-247
-
-
Lander, E.1
Kruglyak, L.2
-
103
-
-
74949092081
-
Detection of nonneutral substitution rates on mammalian phylogenies
-
Pollard K. S., Hubisz M. J., Rosenbloom K. R. & Siepel A. Detection of nonneutral substitution rates on mammalian phylogenies. Genome Res. 20, 110-121 (2010
-
(2010)
Genome Res
, vol.20
, pp. 110-121
-
-
Pollard, K.S.1
Hubisz, M.J.2
Rosenbloom, K.R.3
Siepel, A.4
|