Efficient two-trait-locus linkage analysis through program optimization and parallelization: Application to hypercholesterolemia

European Journal of Human Genetics

Volumn 12, Issue 7, 2004, Pages 542-550

  Dietter, Johannes ^a   Spiegel, Alexander ^b   an Mey, Dieter ^b   Pflug, Hans Joachim ^b   Al Kateb, Hussam ^c   Hoffman, Katrin ^d,e   Wienker, Thomas F ^a   Strauch, Konstantin ^a  

^a UNIVERSITY OF BONN   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Complex traits; Epistasis; Interaction; Locus heterogeneity; Two locus models

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ALGORITHM; ARTICLE; CALCULATION; CHROMOSOME 13Q; CHROMOSOME 1P; COMPUTER PROGRAM; DEVICE; GENE ACTIVITY; GENE LOCUS; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC MARKER; GENETIC TRAIT; HYPERCHOLESTEROLEMIA; HYPOTHESIS; LINKAGE ANALYSIS; PEDIGREE; PRIORITY JOURNAL; SCORING SYSTEM; STATISTICAL ANALYSIS;

COMPUTER SIMULATION; HUMANS; HYPERCHOLESTEROLEMIA; LINKAGE (GENETICS); LOD SCORE; MODELS, GENETIC; PEDIGREE; SOFTWARE;

EID: 4043126045     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201196     Document Type: Article

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