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Volumn 11, Issue 11, 2010, Pages 800-805

Reconciling the analysis of IBD and IBS in complex trait studies

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; CHROMOSOME SEGREGATION; CONCEPTUAL FRAMEWORK; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENETIC MARKER; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; IDENTITY BY DESCENT; IDENTITY BY STATE; INBREEDING DEPRESSION; MUTATION; PRIORITY JOURNAL; QUANTITATIVE GENETICS; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; BIOLOGICAL MODEL; CHROMOSOME; GENETICS; HUMAN; INBREEDING; PEDIGREE; PHYSIOLOGY; POPULATION GENETICS; QUANTITATIVE TRAIT; QUANTITATIVE TRAIT LOCUS;

EID: 77958091897     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg2865     Document Type: Review
Times cited : (262)

References (42)
  • 2
    • 0001507896 scopus 로고
    • Coefficients of inbreeding and relationship
    • Wright, S. Coefficients of inbreeding and relationship. Am. Nat 51, 636-639 (1917).
    • (1917) Am. Nat , vol.51 , pp. 636-639
    • Wright, S.1
  • 3
    • 0000929750 scopus 로고
    • Systems of mating. I. The biometric relations between parent and offspring
    • Wright, S. Systems of mating. I. The biometric relations between parent and offspring. Genetics 6, 111-123 (1921).
    • (1921) Genetics , vol.6 , pp. 111-123
    • Wright, S.1
  • 4
    • 50449089222 scopus 로고    scopus 로고
    • Detection of sharing by descent, long-range phasing and haplotype imputation
    • Kong, A. et al. Detection of sharing by descent, long-range phasing and haplotype imputation. Nature Genet. 40, 1068-1075 (2008).
    • (2008) Nature Genet. , vol.40 , pp. 1068-1075
    • Kong, A.1
  • 5
    • 66249112837 scopus 로고    scopus 로고
    • Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
    • Albrechtsen, A. et al. Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium. Genet. Epidemiol. 33, 266-274 (2009).
    • (2009) Genet. Epidemiol. , vol.33 , pp. 266-274
    • Albrechtsen, A.1
  • 6
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analysis
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analysis. Am. J. Hum. Genet. 81, 559-575 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 7
    • 33645760679 scopus 로고    scopus 로고
    • Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings
    • Visscher, P. M. et al. Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet. 2, 316-325 (2006).
    • (2006) PLoS Genet. , vol.2 , pp. 316-325
    • Visscher, P.M.1
  • 8
    • 70350048798 scopus 로고    scopus 로고
    • The genetics of inbreeding depression
    • Charlesworth, D. & Willis, J. H. The genetics of inbreeding depression. Nature Rev. Genet. 10, 783-796 (2009)
    • (2009) Nature Rev. Genet. , vol.10 , pp. 783-796
    • Charlesworth, D.1    Willis, J.H.2
  • 9
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3. 1 million SNPs
    • The International HapMap Consortium
    • The International HapMap Consortium. A second generation human haplotype map of over 3. 1 million SNPs. Nature 449, 851-862 (2007).
    • (2007) Nature , vol.449 , pp. 851-862
  • 11
    • 0036245438 scopus 로고    scopus 로고
    • Genealogical trees, coalescent theory and the analysis of genetic polymorphisms
    • Rosenberg, N. A. & Nordborg, M. Genealogical trees, coalescent theory and the analysis of genetic polymorphisms. Nature Rev. Genet. 3, 380-390 (2002).
    • (2002) Nature Rev. Genet. , vol.3 , pp. 380-390
    • Rosenberg, N.A.1    Nordborg, M.2
  • 12
    • 0000913208 scopus 로고    scopus 로고
    • eds Balding, D. J., Bishop, M. & Cannings, C.) Wiley, Chichester
    • Nordborg, M. in Handbook of Statistical Genetics (eds Balding, D. J., Bishop, M. & Cannings, C.) 179-212 (Wiley, Chichester, 2001).
    • (2001) Handbook of Statistical Genetics , pp. 179-212
    • Nordborg, M.1
  • 13
    • 45849112925 scopus 로고    scopus 로고
    • Estimation of pairwise identity by descent from dense genetic marker data in a population sample of haplotypes
    • Browning, S. R. Estimation of pairwise identity by descent from dense genetic marker data in a population sample of haplotypes. Genetics 178, 2123-2132 (2008).
    • (2008) Genetics , vol.178 , pp. 2123-2132
    • Browning, S.R.1
  • 14
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio, T A. et al. Finding the missing heritability of complex diseases. Nature 461, 747-753 (2009).
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1
  • 15
    • 55549147191 scopus 로고    scopus 로고
    • The case of the missing heritability
    • Maher, B. The case of the missing heritability. Nature 456, 18-21 (2008).
    • (2008) Nature , vol.456 , pp. 18-21
    • Maher, B.1
  • 18
    • 0242500969 scopus 로고    scopus 로고
    • Novel multilocus measure of linkage disequilibrium to estimate past effective population size
    • Hayes, B. J., Visscher, P. M., McPartlan, H. C. & Goddard, M. E. Novel multilocus measure of linkage disequilibrium to estimate past effective population size. Genome Res. 13, 635-643 (2003).
    • (2003) Genome Res. , vol.13 , pp. 635-643
    • Hayes, B.J.1    Visscher, P.M.2    McPartlan, H.C.3    Goddard, M.E.4
  • 19
    • 0026050476 scopus 로고
    • Inbreeding coefficients and coalescence times
    • Slatkin, M. Inbreeding coefficients and coalescence times. Genet. Res. 58, 167-175 (1991).
    • (1991) Genet. Res. , vol.58 , pp. 167-175
    • Slatkin, M.1
  • 20
    • 0037357345 scopus 로고    scopus 로고
    • Maximum-likelihood estimation of relatedness
    • Milligan, B. G. Maximum-likelihood estimation of relatedness. Genetics 163, 1153-1167 (2003).
    • (2003) Genetics , vol.163 , pp. 1153-1167
    • Milligan, B.G.1
  • 21
    • 77955166399 scopus 로고    scopus 로고
    • Population structure and cryptic relatedness in genetic association studies
    • Astle, W. & Balding, D. J. Population structure and cryptic relatedness in genetic association studies. Stat. Sci. 24, 451-471 (2009).
    • (2009) Stat. Sci. , vol.24 , pp. 451-471
    • Astle, W.1    Balding, D.J.2
  • 22
    • 77954140531 scopus 로고    scopus 로고
    • Common SNPs explain a large proportion of the heritability for human
    • Yang, J. et al. Common SNPs explain a large proportion of the heritability for human. Nature Genet. 42, 565-571 (2010).
    • (2010) Nature Genet. , vol.42 , pp. 565-571
    • Yang, J.1
  • 23
    • 52449110029 scopus 로고    scopus 로고
    • Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
    • Chadeau-Hyam, M. et al. Fregene: simulation of realistic sequence-level data in populations and ascertained samples. BMC Bioinformatics 9, 364-375 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. 364-375
    • Chadeau-Hyam, M.1
  • 24
    • 37249031330 scopus 로고    scopus 로고
    • Sequence-level population simulations over large genomic regions
    • Hoggart, C. J. et al. Sequence-level population simulations over large genomic regions. Genetics 177, 1725-1731 (2007).
    • (2007) Genetics , vol.177 , pp. 1725-1731
    • Hoggart, C.J.1
  • 25
    • 40849097776 scopus 로고    scopus 로고
    • Heritability in the genomics era\ concepts and misconceptions
    • Visscher, P. M., Hill, W. G. & Wray, N. R. Heritability in the genomics era\ concepts and misconceptions. Nature Rev. Genet. 9, 255-266 (2008).
    • (2008) Nature Rev. Genet. , vol.9 , pp. 255-266
    • Visscher, P.M.1    Hill, W.G.2    Wray, N.R.3
  • 26
    • 0035045051 scopus 로고    scopus 로고
    • Prediction of total genetic value using genome-wide dense marker maps
    • Meuwissen, T. H. E., Hayes, B. J. & Goddard, M. E. Prediction of total genetic value using genome-wide dense marker maps. Genetics 157, 1819-1829 (2001).
    • (2001) Genetics , vol.157 , pp. 1819-1829
    • Meuwissen, T.H.E.1    Hayes, B.J.2    Goddard, M.E.3
  • 28
    • 65249179516 scopus 로고    scopus 로고
    • Increased accuracy of artificial selection by using the realized relationship matrix
    • Hayes, B. J., Visscher, P. M. & Goddard, M. E. Increased accuracy of artificial selection by using the realized relationship matrix. Genet. Res. 91, 47-60 (2009).
    • (2009) Genet. Res. , vol.91 , pp. 47-60
    • Hayes, B.J.1    Visscher, P.M.2    Goddard, M.E.3
  • 29
    • 67349287476 scopus 로고    scopus 로고
    • Genomic selection: Prediction of accuracy and maximisation of long term response
    • Goddard, M. E. Genomic selection: prediction of accuracy and maximisation of long term response. Genetica 136, 245-257 (2009).
    • (2009) Genetica , vol.136 , pp. 245-257
    • Goddard, M.E.1
  • 30
    • 37249083895 scopus 로고    scopus 로고
    • The impact of genetic relationship information on genome-assisted breeding values
    • Habier, D., Fernando, R. L. & Dekkers, J. C. The impact of genetic relationship information on genome-assisted breeding values. Genetics 177, 2389-2397 (2008).
    • (2008) Genetics , vol.177 , pp. 2389-2397
    • Habier, D.1    Fernando, R.L.2    Dekkers, J.C.3
  • 31
    • 55849133422 scopus 로고    scopus 로고
    • Efficient methods to compute genomic predictions
    • VanRaden, P. M. Efficient methods to compute genomic predictions. J. Dairy Sci. 91, 4414-4423 (2008).
    • (2008) J. Dairy Sci. , vol.91 , pp. 4414-4423
    • Vanraden, P.M.1
  • 32
    • 33645049607 scopus 로고    scopus 로고
    • The use of linkage disequilibrium to map quantitative trait loci
    • Goddard, M. E. & Meuwissen, T. H. E. The use of linkage disequilibrium to map quantitative trait loci. Aust. J. Exp. Agric. 45, 837-845 (2005).
    • (2005) Aust. J. Exp. Agric. , vol.45 , pp. 837-845
    • Goddard, M.E.1    Meuwissen, T.H.E.2
  • 33
    • 34548443399 scopus 로고    scopus 로고
    • Multipoint identity-by-descent prediction using dense markers to map quantitative trait loci and estimate effective population size
    • Meuwissen, T. H. E. & Goddard, M. E. Multipoint identity-by-descent prediction using dense markers to map quantitative trait loci and estimate effective population size. Genetics 176, 2551-2560 (2007).
    • (2007) Genetics , vol.176 , pp. 2551-2560
    • Meuwissen, T.H.E.1    Goddard, M.E.2
  • 34
    • 0023239442 scopus 로고
    • Homozygosity mapping: A way to map human recessive traits with the DNA of inbred children
    • Lander, E. S. & Botstein D. Homozygosity mapping: a way to map human recessive traits with the DNA of inbred children. Science 236, 1567-1570 (1987).
    • (1987) Science , vol.236 , pp. 1567-1570
    • Lander, E.S.1    Botstein, D.2
  • 35
    • 0345718511 scopus 로고    scopus 로고
    • Estimation of pairwise relatedness with molecular markers
    • Lynch, M. & Ritland, K. Estimation of pairwise relatedness with molecular markers. Genetics 152, 1753-1766 (1999).
    • (1999) Genetics , vol.152 , pp. 1753-1766
    • Lynch, M.1    Ritland, K.2
  • 36
    • 33746808173 scopus 로고    scopus 로고
    • Estimating human inbreeding coefficients: Comparison of genealogical and marker heterozygosity approaches
    • Carothers, A. D. et al. Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches. Ann. Hum. Genet. 70, 666-676 (2006).
    • (2006) Ann. Hum. Genet. , vol.70 , pp. 666-676
    • Carothers, A.D.1
  • 37
    • 50949106932 scopus 로고    scopus 로고
    • Runs of homozygosity in European populations
    • McQuillan, R. et al. Runs of homozygosity in European populations. Am. J. Hum. Genet. 83, 359-372 (2008).
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 359-372
    • McQuillan, R.1
  • 38
    • 0033384124 scopus 로고    scopus 로고
    • The genetic basis of inbreeding depression
    • Charlesworth, B. & Charlesworth, D. The genetic basis of inbreeding depression. Genet. Res. 74, 571-576 (1999).
    • (1999) Genet. Res. , vol.74 , pp. 571-576
    • Charlesworth, B.1    Charlesworth, D.2
  • 39
    • 0033358583 scopus 로고    scopus 로고
    • Long homozygous chromosome segments in reference families from the centre d'étude du polymorphisme humain
    • Broman, K. W. & Weber, J. L. Long homozygous chromosome segments in reference families from the centre d'étude du polymorphisme humain. Am. J. Hum. Genet. 65, 1493-1500 (1999).
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 1493-1500
    • Broman, K.W.1    Weber, J.L.2
  • 41
  • 42
    • 77955133892 scopus 로고    scopus 로고
    • Estimating effects and making predictions from genome-wide marker data
    • Goddard, M. E., Wray, N. R., Verbyla, K. & Visscher, P. M. Estimating effects and making predictions from genome-wide marker data. Stat. Sci. 24, 517-529 (2009).
    • (2009) Stat. Sci. , vol.24 , pp. 517-529
    • Goddard, M.E.1    Wray, N.R.2    Verbyla, K.3    Visscher, P.M.4


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