Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis

Nature Chemical Biology

Volumn 11, Issue 2, 2015, Pages 121-126

  Hammer, Stephan C ^a   Marjanovic, Antonija ^a   Dominicus, Jörg M ^a   Nestl, Bettina M ^a   Hauer, Bernhard ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; CITRONELLAL; DIPLOPTENE; MUTASE; PROTEIN BINDING; PROTON; SQUALENE; SQUALENE-HOPENE CYCLASE; TERPENE; TRITERPENE;

BINDING SITE; BIOCATALYSIS; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; ENZYME SPECIFICITY; GENETICS; PROTEIN ENGINEERING; SITE DIRECTED MUTAGENESIS; STEREOISOMERISM;

ALDEHYDES; BINDING SITES; BIOCATALYSIS; CYCLIZATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOTERPENES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ENGINEERING; PROTONS; SQUALENE; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRITERPENES;

EID: 84928093379     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1719     Document Type: Article

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