Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange

Applied Microbiology and Biotechnology

Volumn 97, Issue 4, 2013, Pages 1571-1580

  Siedenburg, Gabriele ^a   Breuer, Michael ^b   Jendrossek, Dieter ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b BASF SE   (Germany)

Author keywords

Citronellal; Menthol; Monoterpenes; Squalene hopene cyclases

Indexed keywords

ACETOBACTER PASTEURIANUS; ALICYCLOBACILLUS ACIDOCALDARIUS; AROMATIC RESIDUES; BRADYRHIZOBIUM JAPONICUM; CATALYSE; CATALYTIC CENTRE; CITRONELLAL; CYCLASES; GENE PRODUCTS; HYDROPHOBIC RESIDUES; ISOPULEGOL; LINEAR PRECURSORS; MENTHOL; MUTEINS; PROKARYOTIC ENZYMES; SATURATION MUTAGENESIS; STREPTOMYCES COELICOLOR; ZYMOMONAS MOBILIS;

BACILLI; CLONING; CYCLIZATION; ENZYMES; MONOTERPENES; MUTAGENESIS;

AMINO ACIDS;

ALANINE; BACTERIAL ENZYME; CITRONELLAL; CITRONELLAL CYCLASE; CYSTEINE; ISOLEUCINE; PHENYLALANINE; SQUALENE; SQUALENE HOPENE CYCLASE; TYROSINE; UNCLASSIFIED DRUG;

ALCOHOL; ALKENE; AMINO ACID; BACTERIUM; BIOTECHNOLOGY; BIOTRANSFORMATION; CATALYSIS; ENZYME ACTIVITY; HYDROPHOBICITY; MONOTERPENE; MUTATION; PROTEIN;

ACETOBACTER; ACETOBACTER PASTEURIANUS; ALICYCLOBACILLUS ACIDOCALDARIUS; ARTICLE; BRADYRHIZOBIUM JAPONICUM; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; CYCLIZATION; ENZYME SUBSTRATE COMPLEX; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROKARYOTE; STREPTOMYCES COELICOLOR; ZYMOMONAS MOBILIS;

ADENYLATE CYCLASE; ALDEHYDES; AMINO ACID SUBSTITUTION; BACTERIA; BACTERIAL PROTEINS; CATALYTIC DOMAIN; INTRAMOLECULAR TRANSFERASES; MONOTERPENES; MUTATION, MISSENSE; SUBSTRATE SPECIFICITY; ZYMOMONAS;

ACETOBACTER PASTEURIANUS; ALICYCLOBACILLUS ACIDOCALDARIUS; BRADYRHIZOBIUM JAPONICUM; PROKARYOTA; STREPTOMYCES COELICOLOR; ZYMOMONAS MOBILIS;

EID: 84874359209     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4008-1     Document Type: Article

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