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Volumn 76, Issue 10, 2014, Pages 802-809

Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine

Author keywords

ADHD; Benztropine analogs; Cocaine discrimination; Dopamine microdialysis; Drug abuse and addiction; Nucleus accumbens shell

Indexed keywords

BENZATROPINE; COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; METHYLPHENIDATE; DOPAMINE UPTAKE INHIBITOR;

EID: 84927913557     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.03.031     Document Type: Article
Times cited : (37)

References (60)
  • 1
    • 0001845381 scopus 로고
    • Addiction Research Center Inventory (ARCI): Measurement of euphoria and other drug effects
    • Bozarth MA, editor, New York: Springer-Verlag
    • Haertzen CA, Hickey JE (1987): Addiction Research Center Inventory (ARCI): Measurement of euphoria and other drug effects. In: Bozarth MA, editor. Methods of Assessing the Reinforcing Properties of Abused Drugs. New York: Springer-Verlag
    • (1987) Methods of Assessing the Reinforcing Properties of Abused Drugs
    • Haertzen, C.A.1    Hickey, J.E.2
  • 2
    • 0021953291 scopus 로고
    • Drug discrimination studies
    • Holtzman SG (1985): Drug discrimination studies. Drug Alcohol Depend 14:263-282
    • (1985) Drug Alcohol Depend , vol.14 , pp. 263-282
    • Holtzman, S.G.1
  • 3
    • 0023781949 scopus 로고
    • Relationship between the discriminative stimulus properties and subjective effects of drugs
    • Schuster CR, Johanson CE (1988): Relationship between the discriminative stimulus properties and subjective effects of drugs. Psychopharmacol Ser 4:161-175
    • (1988) Psychopharmacol ser , vol.4 , pp. 161-175
    • Schuster, C.R.1    Johanson, C.E.2
  • 4
    • 0030805844 scopus 로고    scopus 로고
    • Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems
    • Callahan PM, De La Garza R 2nd, Cunningham KA (1997): Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems. Pharmacol Biochem Behav 57:601-607
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 601-607
    • Callahan, P.M.1    De La Garza, R.2    Cunningham, K.A.3
  • 5
    • 0024164937 scopus 로고
    • Neurobehavioral pharmacology of cocaine
    • Dworkin SI, Smith JE (1988): Neurobehavioral pharmacology of cocaine. NIDA Res Monogr 88:185-198
    • (1988) NIDA Res Monogr , vol.88 , pp. 185-198
    • Dworkin, S.I.1    Smith, J.E.2
  • 6
    • 27744558550 scopus 로고    scopus 로고
    • Forebrain substrates of reward and motivation
    • Wise RA (2005): Forebrain substrates of reward and motivation. J Comp Neurol 493:115-121
    • (2005) J Comp Neurol , vol.493 , pp. 115-121
    • Wise, R.A.1
  • 7
    • 4544299513 scopus 로고    scopus 로고
    • Methamphetamine discrimination and in vivo microdialysis in squirrel monkeys
    • Czoty PW, Makriyannis A, Bergman J (2004): Methamphetamine discrimination and in vivo microdialysis in squirrel monkeys. Psychopharmacology (Berl) 175:170-178
    • (2004) Psychopharmacology (Berl) , vol.175 , pp. 170-178
    • Czoty, P.W.1    Makriyannis, A.2    Bergman, J.3
  • 8
    • 77952343313 scopus 로고    scopus 로고
    • Monoaminergic psychomotor stimulants: Discriminative stimulus effects and dopamine efflux
    • Desai RI, Paronis CA, Martin J, Desai R, Bergman J (2010): Monoaminergic psychomotor stimulants: Discriminative stimulus effects and dopamine efflux. J Pharmacol Exp Ther 333:834-843
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 834-843
    • Desai, R.I.1    Paronis, C.A.2    Martin, J.3    Desai, R.4    Bergman, J.5
  • 9
    • 0030995126 scopus 로고    scopus 로고
    • Relationship between subjective effects of cocaine and dopamine transporter occupancy
    • Volkow ND, Wang GJ, Fischman MW, Foltin RW, Fowler JS, Abumrad NN, et al. (1997): Relationship between subjective effects of cocaine and dopamine transporter occupancy. Nature 386:827-830
    • (1997) Nature , vol.386 , pp. 827-830
    • Volkow, N.D.1    Wang, G.J.2    Fischman, M.W.3    Foltin, R.W.4    Fowler, J.S.5    Abumrad, N.N.6
  • 10
    • 0024460030 scopus 로고
    • Effects of cocaine and related drugs in nonhuman primates. III. Selfadministration by squirrel monkeys
    • Bergman J, Madras BK, Johnson SE, Spealman RD (1989): Effects of cocaine and related drugs in nonhuman primates. III. Selfadministration by squirrel monkeys. J Pharmacol Exp Ther 251: 150-155
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 150-155
    • Bergman, J.1    Madras, B.K.2    Johnson, S.E.3    Spealman, R.D.4
  • 11
    • 0033967964 scopus 로고    scopus 로고
    • Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects
    • Katz JL, Izenwasser S, Terry P (2000): Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects. Psychopharmacology (Berl) 148:90-98
    • (2000) Psychopharmacology (Berl) , vol.148 , pp. 90-98
    • Katz, J.L.1    Izenwasser, S.2    Terry, P.3
  • 12
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar MJ, Ritz MC, Boja JW (1991): The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14:299-302
    • (1991) Trends Neurosci , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 13
    • 40849134173 scopus 로고    scopus 로고
    • Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors
    • Loland CJ, Desai RI, Zou MF, Cao J, Grundt P, Gerstbrein K, et al. (2008): Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors. Mol Pharmacol 73:813-823
    • (2008) Mol Pharmacol , vol.73 , pp. 813-823
    • Loland, C.J.1    Desai, R.I.2    Zou, M.F.3    Cao, J.4    Grundt, P.5    Gerstbrein, K.6
  • 14
    • 77953363329 scopus 로고    scopus 로고
    • Atypical dopamine uptake inhibitors that provide clues about cocaine's mechanism at the dopamine transporter
    • Newman AH, Katz JL (2009): Atypical dopamine uptake inhibitors that provide clues about cocaine's mechanism at the dopamine transporter. Top Med Chem 4:95-129
    • (2009) Top Med Chem , vol.4 , pp. 95-129
    • Newman, A.H.1    Katz, J.L.2
  • 15
    • 71849111352 scopus 로고    scopus 로고
    • Tropane-based dopamine transporteruptake inhibitors
    • Trudell ML, Izenwasser S, editors, Hoboken, NJ: John Wiley & Sons
    • Runyon SP, Carroll FI (2008): Tropane-based dopamine transporteruptake inhibitors. In: Trudell ML, Izenwasser S, editors. Dopamine Transporters, Chemistry, Biology, and Pharmacology. Hoboken, NJ: John Wiley & Sons, 125-170
    • (2008) Dopamine Transporters, Chemistry, Biology, and Pharmacology , pp. 125-170
    • Runyon, S.P.1    Carroll, F.I.2
  • 16
    • 77953163443 scopus 로고    scopus 로고
    • Discovery of drugs to treat cocaine dependence: Behavioral and neurochemical effects of atypical dopamine transport inhibitors
    • Enna SJ, Williams M, editors, San Diego Academic Press
    • Tanda G, Newman A, Katz JL (2009): Discovery of drugs to treat cocaine dependence: Behavioral and neurochemical effects of atypical dopamine transport inhibitors. In: Enna SJ, Williams M, editors. Advances in Pharmacology, Contemporary Drug Discovery. San Diego: Academic Press, 253-289
    • (2009) Advances in Pharmacology, Contemporary Drug Discovery , pp. 253-289
    • Tanda, G.1    Newman, A.2    Katz, J.L.3
  • 17
    • 84879305802 scopus 로고    scopus 로고
    • Nonclassical pharmacology of the dopamine transporter: Atypical inhibitors, allosteric modulators, and partial substrates
    • Schmitt KC, Rothman RB, Reith ME (2013): Nonclassical pharmacology of the dopamine transporter: Atypical inhibitors, allosteric modulators, and partial substrates. J Pharmacol Exp Ther 346:2-10
    • (2013) J Pharmacol Exp Ther , vol.346 , pp. 2-10
    • Schmitt, K.C.1    Rothman, R.B.2    Reith, M.E.3
  • 18
    • 25644460008 scopus 로고    scopus 로고
    • Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl) methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs
    • Desai RI, Kopajtic TA, French D, Newman AH, Katz JL (2005): Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl) methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs. J Pharmacol Exp Ther 315:397-404
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 397-404
    • Desai, R.I.1    Kopajtic, T.A.2    French, D.3    Newman, A.H.4    Katz, J.L.5
  • 19
    • 84877682107 scopus 로고    scopus 로고
    • Long-acting versus short-acting methylphenidate for paediatric ADHD: A systematic review and meta-analysis of comparative efficacy
    • Punja S, Zorzela L, Hartling L, Urichuk L, Vohra S (2013): Long-acting versus short-acting methylphenidate for paediatric ADHD: A systematic review and meta-analysis of comparative efficacy. BMJ Open 3:e002312
    • (2013) BMJ Open , vol.3 , pp. e002312
    • Punja, S.1    Zorzela, L.2    Hartling, L.3    Urichuk, L.4    Vohra, S.5
  • 21
    • 80054728808 scopus 로고    scopus 로고
    • The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors
    • Schmitt KC, Reith ME (2011): The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PLoS One 6:e25790
    • (2011) PLoS One , vol.6 , pp. e25790
    • Schmitt, K.C.1    Reith, M.E.2
  • 22
    • 0031434059 scopus 로고    scopus 로고
    • Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy] tropane analogues: Selective ligands for the dopamine transporter
    • Agoston GE, Wu JH, Izenwasser S, George C, Katz J, Kline RH, Newman AH (1997): Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy] tropane analogues: Selective ligands for the dopamine transporter. J Med Chem 40:4329-4339
    • (1997) J Med Chem , vol.40 , pp. 4329-4339
    • Agoston, G.E.1    Wu, J.H.2    Izenwasser, S.3    George, C.4    Katz, J.5    Kline, R.H.6    Newman, A.H.7
  • 23
    • 0028804967 scopus 로고
    • Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy) tropane analogs as potent and selective dopamine uptake inhibitors
    • Newman AH, Kline RH, Allen AC, Izenwasser S, George C, Katz JL (1995): Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy) tropane analogs as potent and selective dopamine uptake inhibitors. J Med Chem 38:3933-3940
    • (1995) J Med Chem , vol.38 , pp. 3933-3940
    • Newman, A.H.1    Kline, R.H.2    Allen, A.C.3    Izenwasser, S.4    George, C.5    Katz, J.L.6
  • 24
    • 84921518092 scopus 로고    scopus 로고
    • Attention deficit hyperactivity disorder
    • Barrett JE, Coyle JT, Williams M, editors, New York: Cambridge University Press
    • Berridge CW, Devilbiss DM, Spencer RC, Schmeichel BE, Arnsten FT (2012): Attention deficit hyperactivity disorder. In: Barrett JE, Coyle JT, Williams M, editors. Translational Neuroscience. New York: Cambridge University Press, 303-320
    • (2012) Translational Neuroscience , pp. 303-320
    • Berridge, C.W.1    Devilbiss, D.M.2    Spencer, R.C.3    Schmeichel, B.E.4    Arnsten, F.T.5
  • 25
    • 84866423394 scopus 로고    scopus 로고
    • A selective dopamine reuptake inhibitor improves prefrontal cortex-dependent cognitive function: Potential relevance to attention deficit hyperactivity disorder
    • Schmeichel BE, Zemlan FP, Berridge CW (2013): A selective dopamine reuptake inhibitor improves prefrontal cortex-dependent cognitive function: Potential relevance to attention deficit hyperactivity disorder. Neuropharmacology 64:321-328
    • (2013) Neuropharmacology , vol.64 , pp. 321-328
    • Schmeichel, B.E.1    Zemlan, F.P.2    Berridge, C.W.3
  • 26
    • 0030761521 scopus 로고    scopus 로고
    • Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism
    • Tanda G, Pontieri FE, Di Chiara G (1997): Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism. Science 276:2048-2050
    • (1997) Science , vol.276 , pp. 2048-2050
    • Tanda, G.1    Pontieri, F.E.2    Di Chiara, G.3
  • 27
    • 0030666362 scopus 로고    scopus 로고
    • Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine
    • Tanda G, Pontieri FE, Frau R, Di Chiara G (1997): Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine. Eur J Neurosci 9:2077-2085
    • (1997) Eur J Neurosci , vol.9 , pp. 2077-2085
    • Tanda, G.1    Pontieri, F.E.2    Frau, R.3    Di Chiara, G.4
  • 28
    • 0032773208 scopus 로고    scopus 로고
    • Functional-anatomical implications of the nucleus accumbens core and shell subterritories
    • Zahm DS (1999): Functional-anatomical implications of the nucleus accumbens core and shell subterritories. Ann N Y Acad Sci. 877:113-128
    • (1999) Ann N y Acad Sci , vol.877 , pp. 113-128
    • Zahm, D.S.1
  • 29
    • 0029583656 scopus 로고
    • Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the"core" of the rat nucleus accumbens
    • Pontieri FE, Tanda G, Di Chiara G (1995): Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the"shell" as compared with the"core" of the rat nucleus accumbens. Proc Natl Acad Sci U S A 92:12304-12308
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 12304-12308
    • Pontieri, F.E.1    Tanda, G.2    Di Chiara, G.3
  • 31
    • 78650830054 scopus 로고    scopus 로고
    • Sigma receptor agonists: Receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis
    • Garces-Ramirez L, Green JL, Hiranita T, Kopajtic TA, Mereu M, Thomas A, et al. (2011): Sigma receptor agonists: Receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis. Biol Psychiatry 69:208-217
    • (2011) Biol Psychiatry , vol.69 , pp. 208-217
    • Garces-Ramirez, L.1    Green, J.L.2    Hiranita, T.3    Kopajtic, T.A.4    Mereu, M.5    Thomas, A.6
  • 32
    • 18044374657 scopus 로고    scopus 로고
    • Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: Comparison with effects of cocaine
    • Tanda G, Ebbs A, Newman AH, Katz JL (2005): Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: Comparison with effects of cocaine. J Pharmacol Exp Ther 313:613-620
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 613-620
    • Tanda, G.1    Ebbs, A.2    Newman, A.H.3    Katz, J.L.4
  • 33
    • 33947428268 scopus 로고    scopus 로고
    • Effects of muscarinic M1 receptor blockade on cocaineinduced elevations of brain dopamine levels and locomotor behavior in rats
    • Tanda G, Ebbs AL, Kopajtic TA, Elias LM, Campbell BL, Newman AH, Katz JL (2007): Effects of muscarinic M1 receptor blockade on cocaineinduced elevations of brain dopamine levels and locomotor behavior in rats. J Pharmacol Exp Ther 321:334-344
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 334-344
    • Tanda, G.1    Ebbs, A.L.2    Kopajtic, T.A.3    Elias, L.M.4    Campbell, B.L.5    Newman, A.H.6    Katz, J.L.7
  • 35
    • 0027418626 scopus 로고
    • The role of monoamine uptake in the discriminative stimulus effects of cocaine and related compounds
    • Baker LE, Riddle EE, Saunders RB, Appel JB (1993): The role of monoamine uptake in the discriminative stimulus effects of cocaine and related compounds. Behav Pharmacol 4:69-79
    • (1993) Behav Pharmacol , vol.4 , pp. 69-79
    • Baker, L.E.1    Riddle, E.E.2    Saunders, R.B.3    Appel, J.B.4
  • 36
    • 0001321213 scopus 로고
    • Involvement of dopamine uptake in the discriminative stimulus effects of cocaine
    • Broadbent J, Michael EK, Riddle EE, Apple JB (1991): Involvement of dopamine uptake in the discriminative stimulus effects of cocaine. Behav Pharmacol 2:187-197
    • (1991) Behav Pharmacol , vol.2 , pp. 187-197
    • Broadbent, J.1    Michael, E.K.2    Riddle, E.E.3    Apple, J.B.4
  • 37
    • 84883462310 scopus 로고    scopus 로고
    • Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change
    • Tanda G, Li SM, Mereu M, Thomas AM, Ebbs AL, Chun LE, et al. (2013): Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change. Psychopharmacology (Berl) 229:307-321
    • (2013) Psychopharmacology (Berl) , vol.229 , pp. 307-321
    • Tanda, G.1    Li, S.M.2    Mereu, M.3    Thomas, A.M.4    Ebbs, A.L.5    Chun, L.E.6
  • 38
    • 34247402099 scopus 로고    scopus 로고
    • Abuse liability of medications used to treat attention-deficit/hyperactivity disorder (ADHD)
    • quiz 43-44
    • Kollins SH (2007): Abuse liability of medications used to treat attention-deficit/hyperactivity disorder (ADHD). Am J Addict 16(suppl 1): 35-42; quiz 43-44
    • (2007) Am J Addict , vol.16 , pp. 35-42
    • Kollins, S.H.1
  • 41
    • 65649118524 scopus 로고    scopus 로고
    • Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: Comparisons with monoamine uptake inhibitors
    • Hiranita T, Soto PL, Newman AH, Katz JL (2009): Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: Comparisons with monoamine uptake inhibitors. J Pharmacol Exp Ther 329:677-686
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 677-686
    • Hiranita, T.1    Soto, P.L.2    Newman, A.H.3    Katz, J.L.4
  • 42
    • 78751474117 scopus 로고    scopus 로고
    • N-substituted benztropine analogs: Selective dopamine transporter ligands with a fast onset of action and minimal cocainelike behavioral effects
    • Li SM, Kopajtic TA, O'Callaghan MJ, Agoston GE, Cao J, Newman AH, et al. (2011): N-substituted benztropine analogs: Selective dopamine transporter ligands with a fast onset of action and minimal cocainelike behavioral effects. J Pharmacol Exp Ther 336:575-585
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 575-585
    • Li, S.M.1    Kopajtic, T.A.2    O'Callaghan, M.J.3    Agoston, G.E.4    Cao, J.5    Newman, A.H.6
  • 43
    • 84891644551 scopus 로고    scopus 로고
    • Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats
    • Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL (2014): Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats. J Pharmacol Exp Ther 348:174-191
    • (2014) J Pharmacol Exp Ther , vol.348 , pp. 174-191
    • Hiranita, T.1    Kohut, S.J.2    Soto, P.L.3    Tanda, G.4    Kopajtic, T.A.5    Katz, J.L.6
  • 44
    • 77953355881 scopus 로고    scopus 로고
    • The high affinity dopamine uptake inhibitor, JHW 007, blocks cocaineinduced reward, locomotor stimulation and sensitization
    • Velazquez-Sanchez C, Ferragud A, Murga J, Carda M, Canales JJ (2010): The high affinity dopamine uptake inhibitor, JHW 007, blocks cocaineinduced reward, locomotor stimulation and sensitization. Eur Neuropsychopharmacol 20:501-508
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 501-508
    • Velazquez-Sanchez, C.1    Ferragud, A.2    Murga, J.3    Carda, M.4    Canales, J.J.5
  • 46
    • 2542420799 scopus 로고    scopus 로고
    • Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine
    • Chen N, Zhen J, Reith ME (2004): Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine. J Neurochem 89: 853-864
    • (2004) J Neurochem , vol.89 , pp. 853-864
    • Chen, N.1    Zhen, J.2    Reith, M.E.3
  • 47
    • 78649590475 scopus 로고    scopus 로고
    • Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability
    • Kopajtic TA, Liu Y, Surratt CK, Donovan DM, Newman AH, Katz JL (2010): Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability. J Pharmacol Exp Ther 335:703-714
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 703-714
    • Kopajtic, T.A.1    Liu, Y.2    Surratt, C.K.3    Donovan, D.M.4    Newman, A.H.5    Katz, J.L.6
  • 48
    • 0035800785 scopus 로고    scopus 로고
    • The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter
    • Reith ME, Berfield JL, Wang LC, Ferrer JV, Javitch JA (2001): The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. J Biol Chem 276:29012-29018
    • (2001) J Biol Chem , vol.276 , pp. 29012-29018
    • Reith, M.E.1    Berfield, J.L.2    Wang, L.C.3    Ferrer, J.V.4    Javitch, J.A.5
  • 49
    • 27144433625 scopus 로고    scopus 로고
    • Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs
    • Campbell VC, Kopajtic TA, Newman AH, Katz JL (2005): Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs. J Pharmacol Exp Ther 315: 631-640
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 631-640
    • Campbell, V.C.1    Kopajtic, T.A.2    Newman, A.H.3    Katz, J.L.4
  • 50
    • 45249096712 scopus 로고    scopus 로고
    • Cocaine-like neurochemical effects of antihistaminic medications
    • Tanda G, Kopajtic TA, Katz JL (2008): Cocaine-like neurochemical effects of antihistaminic medications. J Neurochem 106:147-157
    • (2008) J Neurochem , vol.106 , pp. 147-157
    • Tanda, G.1    Kopajtic, T.A.2    Katz, J.L.3
  • 51
    • 2142715947 scopus 로고    scopus 로고
    • Effects of N-substituted analogs of benztropine: Diminished cocaine-like effects in dopamine transporter ligands
    • Katz JL, Kopajtic TA, Agoston GE, Newman AH (2004): Effects of N-substituted analogs of benztropine: Diminished cocaine-like effects in dopamine transporter ligands. J Pharmacol Exp Ther 309:650-660
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 650-660
    • Katz, J.L.1    Kopajtic, T.A.2    Agoston, G.E.3    Newman, A.H.4
  • 52
    • 80054792966 scopus 로고    scopus 로고
    • Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and sigma receptors
    • Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH, et al. (2011): Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and sigma receptors. J Pharmacol Exp Ther 339:662-677
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 662-677
    • Hiranita, T.1    Soto, P.L.2    Kohut, S.J.3    Kopajtic, T.4    Cao, J.5    Newman, A.H.6
  • 53
    • 0033615028 scopus 로고    scopus 로고
    • Pharmacotherapies for treatment of cocaine abuse: Preclinical aspects
    • Carroll FI, Howell LL, Kuhar MJ (1999): Pharmacotherapies for treatment of cocaine abuse: Preclinical aspects. J Med Chem 42:2721-2736
    • (1999) J Med Chem , vol.42 , pp. 2721-2736
    • Carroll, F.I.1    Howell, L.L.2    Kuhar, M.J.3
  • 54
    • 84898008454 scopus 로고    scopus 로고
    • 2-Isoxazol-3-phenyltropane derivatives of cocaine: Molecular and atypical system effects at the dopamine transporter
    • Hiranita T, Wilkinson DS, Hong WC, Zou MF, Kopajtic TA, Soto PL, et al. (2014): 2-Isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter. J Pharmacol Exp Ther 349:297-309. doi:10.1124/jpet.113.212738
    • (2014) J Pharmacol Exp Ther , vol.349 , pp. 297-309
    • Hiranita, T.1    Wilkinson, D.S.2    Hong, W.C.3    Zou, M.F.4    Kopajtic, T.A.5    Soto, P.L.6
  • 55
    • 14244260728 scopus 로고    scopus 로고
    • Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine
    • Desai RI, Kopajtic TA, Koffarnus M, Newman AH, Katz JL (2005): Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine. J Neurosci 25:1889-1893
    • (2005) J Neurosci , vol.25 , pp. 1889-1893
    • Desai, R.I.1    Kopajtic, T.A.2    Koffarnus, M.3    Newman, A.H.4    Katz, J.L.5
  • 56
    • 0142148142 scopus 로고    scopus 로고
    • Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques
    • Raje S, Cao J, Newman AH, Gao H, Eddington ND (2003): Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques. J Pharmacol Exp Ther 307:801-808
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 801-808
    • Raje, S.1    Cao, J.2    Newman, A.H.3    Gao, H.4    Eddington, N.D.5
  • 57
    • 18044363842 scopus 로고    scopus 로고
    • Pharmacodynamic assessment of the benztropine analogues AHN- 1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling
    • Raje S, Cornish J, Newman AH, Cao J, Katz JL, Eddington ND (2005): Pharmacodynamic assessment of the benztropine analogues AHN- 1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling. Pharm Res 22:603-612
    • (2005) Pharm Res , vol.22 , pp. 603-612
    • Raje, S.1    Cornish, J.2    Newman, A.H.3    Cao, J.4    Katz, J.L.5    Eddington, N.D.6
  • 59
    • 77955170298 scopus 로고    scopus 로고
    • Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons
    • Katz NS, Guiard BP, El Mansari M, Blier P (2010): Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. J Psychopharmacol 24:1223-1235
    • (2010) J Psychopharmacol , vol.24 , pp. 1223-1235
    • Katz, N.S.1    Guiard, B.P.2    El Mansari, M.3    Blier, P.4
  • 60
    • 0036721054 scopus 로고    scopus 로고
    • Probes for the dopamine transporter: New leads toward a cocaine-abuse therapeutic-A focus on analogues of benztropine and rimcazole
    • Newman AH, Kulkarni S (2002): Probes for the dopamine transporter: New leads toward a cocaine-abuse therapeutic-A focus on analogues of benztropine and rimcazole. Med Res Rev 22:429-464.
    • (2002) Med Res Rev , vol.22 , pp. 429-464
    • Newman, A.H.1    Kulkarni, S.2


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