Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis

Respiratory Research

Volumn 16, Issue 1, 2015, Pages

  De Langhe, Ellen ^a   Cailotto, Frederic ^a   De Vooght, Vanessa ^b   Aznar Lopez, Carolina ^a   Vanoirbeek, Jeroen A ^b   Luyten, Frank P ^a   Lories, Rik J U ^a  

^a SKELETAL BIOLOGY AND ENGINEERING RESEARCH CENTER   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Bleomycin; Bone morphogenetic proteins; Pulmonary fibrosis; Transforming growth factor beta

Indexed keywords

BLEOMYCIN; BONE MORPHOGENETIC PROTEIN; COLLAGEN; NOGGIN; PHOSPHATE BUFFERED SALINE; TRANSFORMING GROWTH FACTOR BETA; CARRIER PROTEIN; NOGGIN PROTEIN; RECEPTOR REGULATED SMAD PROTEIN; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; CONTROLLED STUDY; FIBROGENESIS; GENE EXPRESSION; HAPLOINSUFFICIENCY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG COMPLIANCE; LUNG FUNCTION TEST; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CHEMICALLY INDUCED; DISEASE MODEL; DOWN REGULATION; GENETICS; KNOCKOUT MOUSE; LUNG; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY FIBROSIS; TIME FACTOR;

ANIMALS; APOPTOSIS; BLEOMYCIN; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; CELL PROLIFERATION; COLLAGEN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HAPLOINSUFFICIENCY; LUNG; LUNG COMPLIANCE; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY FIBROSIS; SIGNAL TRANSDUCTION; SMAD PROTEINS, RECEPTOR-REGULATED; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84927777901     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0202-x     Document Type: Article

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