Canonical Wnt signaling skews TGF-β Signaling in chondrocytes towards signaling via ALK1 and smad 1/5/8

Cellular Signalling

Volumn 26, Issue 5, 2014, Pages 951-958

  Van den Bosch, Martijn H ^a   Blom, Arjen B ^a   van Lent, Peter L ^a   van Beuningen, Henk M ^a   Blaney Davidson, Esmeralda N ^a   van der Kraan, Peter M ^a   van den Berg, Wim B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Chondrocyte hypertrophy; Osteoarthritis; Smad signaling; TGF ; Wnt signaling

Indexed keywords

CHONDROCYTE HYPERTROPHY; OSTEOARTHRITIS; SMAD SIGNALING; TGF-Β; WNT SIGNALING;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; BETA CATENIN; CCN INTERCELLULAR SIGNALING PROTEINS; CELL LINE; CHONDROCYTES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS; WNT3A PROTEIN;

EID: 84893520309     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.01.021     Document Type: Article

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