-
1
-
-
79955601433
-
The emerging role of innate immunity in the heart and vascular system: For whom the cell tolls
-
Mann DL. The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls. Circ Res. 2011;108:1133-1145.
-
(2011)
Circ Res.
, vol.108
, pp. 1133-1145
-
-
Mann, D.L.1
-
2
-
-
33646539111
-
The tumor necrosis factor superfamily in heart failure
-
Ueland T, Aukrust P, Damas JK, Gullestad L, Yndestad A. The tumor necrosis factor superfamily in heart failure. Future Cardiol. 2006;2:101-111.
-
(2006)
Future Cardiol.
, vol.2
, pp. 101-111
-
-
Ueland, T.1
Aukrust, P.2
Damas, J.K.3
Gullestad, L.4
Yndestad, A.5
-
3
-
-
0032515948
-
Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte
-
Nakano M, Knowlton AA, Dibbs Z, Mann DL. Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte. Circulation. 1998;97:1392-1400.
-
(1998)
Circulation.
, vol.97
, pp. 1392-1400
-
-
Nakano, M.1
Knowlton, A.A.2
Dibbs, Z.3
Mann, D.L.4
-
4
-
-
76549100504
-
The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart
-
Burchfield JS, Dong JW, Sakata Y, Gao F, Tzeng HP, Topkara VK, Entman ML, Sivasubramanian N, Mann DL. The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart. Circ Heart Fail. 2010;3:157-164.
-
(2010)
Circ Heart Fail.
, vol.3
, pp. 157-164
-
-
Burchfield, J.S.1
Dong, J.W.2
Sakata, Y.3
Gao, F.4
Tzeng, H.P.5
Topkara, V.K.6
Entman, M.L.7
Sivasubramanian, N.8
Mann, D.L.9
-
5
-
-
33644876126
-
Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase)
-
Lecour S, Suleman N, Deuchar GA, Somers S, Lacerda L, Huisamen B, Opie LH. Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). Circulation. 2005;112:3911-3918.
-
(2005)
Circulation.
, vol.112
, pp. 3911-3918
-
-
Lecour, S.1
Suleman, N.2
Deuchar, G.A.3
Somers, S.4
Lacerda, L.5
Huisamen, B.6
Opie, L.H.7
-
6
-
-
0034625134
-
Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction
-
Kurrelmeyer KM, Michael LH, Baumgarten G, Taffet GE, Peschon JJ, Sivasubramanian N, Entman ML, Mann DL. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 2000;97:5456-5461.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, pp. 5456-5461
-
-
Kurrelmeyer, K.M.1
Michael, L.H.2
Baumgarten, G.3
Taffet, G.E.4
Peschon, J.J.5
Sivasubramanian, N.6
Entman, M.L.7
Mann, D.L.8
-
7
-
-
0028978626
-
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
-
Rothe M, Sarma V, Dixit VM, Goeddel DV. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science. 1995;269:1424-1427.
-
(1995)
Science.
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
8
-
-
0345490687
-
Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury
-
Hausenloy DJ, Duchen MR, Yellon DM. Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury. Cardiovasc Res. 2003;60:617-625.
-
(2003)
Cardiovasc Res.
, vol.60
, pp. 617-625
-
-
Hausenloy, D.J.1
Duchen, M.R.2
Yellon, D.M.3
-
9
-
-
77953704724
-
Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
-
Carreira RS, Lee Y, Ghochani M, Gustafsson ÅB, Gottlieb RA. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy. 2010;6:462-472.
-
(2010)
Autophagy.
, vol.6
, pp. 462-472
-
-
Carreira, R.S.1
Lee, Y.2
Ghochani, M.3
Gustafsson Å., B.4
Gottlieb, R.A.5
-
10
-
-
84872283780
-
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction
-
Kubli DA, Zhang X, Lee Y, Hanna RA, Quinsay MN, Nguyen CK, Jimenez R, Petrosyan S, Murphy AN, Gustafsson AB. Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction. J Biol Chem. 2013;288:915-926.
-
(2013)
J Biol Chem.
, vol.288
, pp. 915-926
-
-
Kubli, D.A.1
Zhang, X.2
Lee, Y.3
Hanna, R.A.4
Quinsay, M.N.5
Nguyen, C.K.6
Jimenez, R.7
Petrosyan, S.8
Murphy, A.N.9
Gustafsson, A.B.10
-
11
-
-
79958172986
-
Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1
-
Huang C, Andres AM, Ratliff EP, Hernandez G, Lee P, Gottlieb RA. Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. PLoS One. 2011;6:e20975.
-
(2011)
PLoS One.
, vol.6
, pp. e20975
-
-
Huang, C.1
Andres, A.M.2
Ratliff, E.P.3
Hernandez, G.4
Lee, P.5
Gottlieb, R.A.6
-
12
-
-
61949346360
-
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
-
Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC, Gottlieb RA. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol. 2009;296:H470-H479.
-
(2009)
Am J Physiol Heart Circ Physiol.
, vol.296
, pp. H470-H479
-
-
Yuan, H.1
Perry, C.N.2
Huang, C.3
Iwai-Kanai, E.4
Carreira, R.S.5
Glembotski, C.C.6
Gottlieb, R.A.7
-
13
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol. 2010;191:1367-1380.
-
(2010)
J Cell Biol.
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
14
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol. 2008;183:795-803.
-
(2008)
J Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
15
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol. 2010;8:e1000298.
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
16
-
-
79959344616
-
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
-
Billia F, Hauck L, Konecny F, Rao V, Shen J, Mak TW. PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function. Proc Natl Acad Sci USA. 2011;108:9572-9577.
-
(2011)
Proc Natl Acad Sci USA.
, vol.108
, pp. 9572-9577
-
-
Billia, F.1
Hauck, L.2
Konecny, F.3
Rao, V.4
Shen, J.5
Mak, T.W.6
-
17
-
-
84881329174
-
Parkin deficiency results in accumulation of abnormal mitochondria in aging myocytes
-
Kubli DA, Quinsay MN, Gustafsson AB. Parkin deficiency results in accumulation of abnormal mitochondria in aging myocytes. Commun Integr Biol. 2013;6:e24511.
-
(2013)
Commun Integr Biol.
, vol.6
, pp. e24511
-
-
Kubli, D.A.1
Quinsay, M.N.2
Gustafsson, A.B.3
-
18
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature. 2010;465:1084-1088.
-
(2010)
Nature.
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
Milstien, S.11
Spiegel, S.12
-
19
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell. 2011;146:448-461.
-
(2011)
Cell.
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
20
-
-
40149110912
-
Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling
-
Lad SP, Yang G, Scott DA, Chao TH, Correia Jda S, de la Torre JC, Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Mol Immunol. 2008;45:2277-2287.
-
(2008)
Mol Immunol.
, vol.45
, pp. 2277-2287
-
-
Lad, S.P.1
Yang, G.2
Scott, D.A.3
Chao, T.H.4
Correia Jda, S.5
De La Torre, J.C.6
Li, E.7
-
21
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF 3. Cell. 2005;122:669-682.
-
(2005)
Cell.
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
22
-
-
84863192578
-
Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury
-
Ma X, Liu H, Foyil SR, Godar RJ, Weinheimer CJ, Hill JA, Diwan A. Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury. Circulation. 2012;125:3170-3181.
-
(2012)
Circulation.
, vol.125
, pp. 3170-3181
-
-
Ma, X.1
Liu, H.2
Foyil, S.R.3
Godar, R.J.4
Weinheimer, C.J.5
Hill, J.A.6
Diwan, A.7
-
23
-
-
84859151396
-
Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death
-
Ma X, Godar RJ, Liu H, Diwan A. Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death. Autophagy. 2012;8:297-309.
-
(2012)
Autophagy.
, vol.8
, pp. 297-309
-
-
Ma, X.1
Godar, R.J.2
Liu, H.3
Diwan, A.4
-
24
-
-
0035859841
-
Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor
-
Sivasubramanian N, Coker ML, Kurrelmeyer KM, MacLellan WR, DeMayo FJ, Spinale FG, Mann DL. Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2001;104:826-831.
-
(2001)
Circulation.
, vol.104
, pp. 826-831
-
-
Sivasubramanian, N.1
Coker, M.L.2
Kurrelmeyer, K.M.3
Maclellan, W.R.4
Demayo, F.J.5
Spinale, F.G.6
Mann, D.L.7
-
25
-
-
77955713258
-
TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L)
-
Kim JJ, Lee SB, Park JK, Yoo YD. TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L). Cell Death Differ. 2010;17:1420-1434.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1420-1434
-
-
Kim, J.J.1
Lee, S.B.2
Park, J.K.3
Yoo, Y.D.4
-
26
-
-
4444341939
-
Compartmentalization of TNF receptor 1 signaling: Internalized TNF receptosomes as death signaling vesicles
-
Schneider-Brachert W, Tchikov V, Neumeyer J, Jakob M, Winoto-Morbach S, Held-Feindt J, Heinrich M, Merkel O, Ehrenschwender M, Adam D, Mentlein R, Kabelitz D, Schütze S. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity. 2004;21:415-428.
-
(2004)
Immunity.
, vol.21
, pp. 415-428
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Neumeyer, J.3
Jakob, M.4
Winoto-Morbach, S.5
Held-Feindt, J.6
Heinrich, M.7
Merkel, O.8
Ehrenschwender, M.9
Adam, D.10
Mentlein, R.11
Kabelitz, D.12
Schütze, S.13
-
27
-
-
84879226604
-
Tumor necrosis factor receptor-associated factor 2 signaling provokes adverse cardiac remodeling in the adult mammalian heart
-
Divakaran VG, Evans S, Topkara VK, Diwan A, Burchfield J, Gao F, Dong J, Tzeng HP, Sivasubramanian N, Barger PM, Mann DL. Tumor necrosis factor receptor-associated factor 2 signaling provokes adverse cardiac remodeling in the adult mammalian heart. Circ Heart Fail. 2013;6:535-543.
-
(2013)
Circ Heart Fail.
, vol.6
, pp. 535-543
-
-
Divakaran, V.G.1
Evans, S.2
Topkara, V.K.3
Diwan, A.4
Burchfield, J.5
Gao, F.6
Dong, J.7
Tzeng, H.P.8
Sivasubramanian, N.9
Barger, P.M.10
Mann, D.L.11
-
28
-
-
44649162611
-
Desmin mediates TNF-alpha-induced aggregate formation and intercalated disk reorganization in heart failure
-
Panagopoulou P, Davos CH, Milner DJ, Varela E, Cameron J, Mann DL, Capetanaki Y. Desmin mediates TNF-alpha-induced aggregate formation and intercalated disk reorganization in heart failure. J Cell Biol. 2008;181:761-775.
-
(2008)
J Cell Biol.
, vol.181
, pp. 761-775
-
-
Panagopoulou, P.1
Davos, C.H.2
Milner, D.J.3
Varela, E.4
Cameron, J.5
Mann, D.L.6
Capetanaki, Y.7
-
29
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol. 2010;22:124-131.
-
(2010)
Curr Opin Cell Biol.
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
30
-
-
47549114849
-
Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
-
Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP. Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008;22:1948-1961.
-
(2008)
Genes Dev.
, vol.22
, pp. 1948-1961
-
-
Lai, L.1
Leone, T.C.2
Zechner, C.3
Schaeffer, P.J.4
Kelly, S.M.5
Flanagan, D.P.6
Medeiros, D.M.7
Kovacs, A.8
Kelly, D.P.9
-
31
-
-
69949112039
-
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
-
Rouschop KM, Ramaekers CH, Schaaf MB, Keulers TG, Savelkouls KG, Lambin P, Koritzinsky M, Wouters BG. Autophagy is required during cycling hypoxia to lower production of reactive oxygen species. Radiother Oncol. 2009;92:411-416.
-
(2009)
Radiother Oncol.
, vol.92
, pp. 411-416
-
-
Rouschop, K.M.1
Ramaekers, C.H.2
Schaaf, M.B.3
Keulers, T.G.4
Savelkouls, K.G.5
Lambin, P.6
Koritzinsky, M.7
Wouters, B.G.8
-
32
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science. 2011;331:456-461.
-
(2011)
Science.
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
Asara, J.M.11
Fitzpatrick, J.12
Dillin, A.13
Viollet, B.14
Kundu, M.15
Hansen, M.16
Shaw, R.J.17
-
33
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem. 2008;283:10892-10903.
-
(2008)
J Biol Chem.
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
34
-
-
33847191686
-
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling
-
Henn IH, Bouman L, Schlehe JS, Schlierf A, Schramm JE, Wegener E, Nakaso K, Culmsee C, Berninger B, Krappmann D, Tatzelt J, Winklhofer KF. Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. J Neurosci. 2007;27:1868-1878.
-
(2007)
J Neurosci.
, vol.27
, pp. 1868-1878
-
-
Henn, I.H.1
Bouman, L.2
Schlehe, J.S.3
Schlierf, A.4
Schramm, J.E.5
Wegener, E.6
Nakaso, K.7
Culmsee, C.8
Berninger, B.9
Krappmann, D.10
Tatzelt, J.11
Winklhofer, K.F.12
-
35
-
-
1542380581
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB
-
Habelhah H, Takahashi S, Cho SG, Kadoya T, Watanabe T, Ronai Z. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J. 2004;23:322-332.
-
(2004)
EMBO J.
, vol.23
, pp. 322-332
-
-
Habelhah, H.1
Takahashi, S.2
Cho, S.G.3
Kadoya, T.4
Watanabe, T.5
Ronai, Z.6
-
36
-
-
84862928017
-
Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-induced JNK activation and inflammation
-
Liu J, Yan J, Jiang S, Wen J, Chen L, Zhao Y, Lin A. Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-induced JNK activation and inflammation. Proc Natl Acad Sci USA. 2012;109:191-196.
-
(2012)
Proc Natl Acad Sci USA.
, vol.109
, pp. 191-196
-
-
Liu, J.1
Yan, J.2
Jiang, S.3
Wen, J.4
Chen, L.5
Zhao, Y.6
Lin, A.7
-
37
-
-
84898668073
-
Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury
-
Tzeng HP, Evans S, Gao F, Chambers K, Topkara VK, Sivasubramanian N, Barger PM, Mann DL. Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury. J Am Heart Assoc. 2014;3:e000662.
-
(2014)
J Am Heart Assoc.
, vol.3
, pp. e000662
-
-
Tzeng, H.P.1
Evans, S.2
Gao, F.3
Chambers, K.4
Topkara, V.K.5
Sivasubramanian, N.6
Barger, P.M.7
Mann, D.L.8
-
38
-
-
84878472085
-
PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates
-
Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R. PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates. Hum Mol Genet. 2013;22:2423-2434.
-
(2013)
Hum Mol Genet.
, vol.22
, pp. 2423-2434
-
-
Matsui, H.1
Gavinio, R.2
Asano, T.3
Uemura, N.4
Ito, H.5
Taniguchi, Y.6
Kobayashi, Y.7
Maki, T.8
Shen, J.9
Takeda, S.10
Uemura, K.11
Yamakado, H.12
Takahashi, R.13
-
39
-
-
79955951399
-
Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease
-
Piao JH, Hasegawa M, Heissig B, Hattori K, Takeda K, Iwakura Y, Okumura K, Inohara N, Nakano H. Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease. J Biol Chem. 2011;286:17879-17888.
-
(2011)
J Biol Chem.
, vol.286
, pp. 17879-17888
-
-
Piao, J.H.1
Hasegawa, M.2
Heissig, B.3
Hattori, K.4
Takeda, K.5
Iwakura, Y.6
Okumura, K.7
Inohara, N.8
Nakano, H.9
-
40
-
-
0031463025
-
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, de la Pompa JL, Ferrick D, Hum B, Iscove N, Ohashi P, Rothe M, Goeddel DV, Mak TW. Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity. 1997;7:715-725.
-
(1997)
Immunity.
, vol.7
, pp. 715-725
-
-
Yeh, W.C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
De La Pompa, J.L.7
Ferrick, D.8
Hum, B.9
Iscove, N.10
Ohashi, P.11
Rothe, M.12
Goeddel, D.V.13
Mak, T.W.14
-
41
-
-
0030032106
-
TRADD-TRAF2 and TRADDFADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADDFADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 1996;84:299-308.
-
(1996)
Cell.
, vol.84
, pp. 299-308
-
-
Hsu, H.1
Shu, H.B.2
Pan, M.G.3
Goeddel, D.V.4
-
42
-
-
84860705893
-
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
-
Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, Oyabu J, Murakawa T, Nakayama H, Nishida K, Akira S, Yamamoto A, Komuro I, Otsu K. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature. 2012;485:251-255.
-
(2012)
Nature.
, vol.485
, pp. 251-255
-
-
Oka, T.1
Hikoso, S.2
Yamaguchi, O.3
Taneike, M.4
Takeda, T.5
Tamai, T.6
Oyabu, J.7
Murakawa, T.8
Nakayama, H.9
Nishida, K.10
Akira, S.11
Yamamoto, A.12
Komuro, I.13
Otsu, K.14
-
43
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2011;469:221-225.
-
(2011)
Nature.
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
44
-
-
0033198702
-
TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses
-
Nguyen LT, Duncan GS, Mirtsos C, Ng M, Speiser DE, Shahinian A, Marino MW, Mak TW, Ohashi PS, Yeh WC. TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity. 1999;11:379-389.
-
(1999)
Immunity.
, vol.11
, pp. 379-389
-
-
Nguyen, L.T.1
Duncan, G.S.2
Mirtsos, C.3
Ng, M.4
Speiser, D.E.5
Shahinian, A.6
Marino, M.W.7
Mak, T.W.8
Ohashi, P.S.9
Yeh, W.C.10
-
45
-
-
81055145273
-
Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFB2 signaling that contributes to autoimmunity
-
Lin WJ, Su YW, Lu YC, Hao Z, Chio II, Chen NJ, Brüstle A, Li WY, Mak TW. Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFB2 signaling that contributes to autoimmunity. Proc Natl Acad Sci USA. 2011;108:18354-18359.
-
(2011)
Proc Natl Acad Sci USA.
, vol.108
, pp. 18354-18359
-
-
Lin, W.J.1
Su, Y.W.2
Lu, Y.C.3
Hao, Z.4
Chio, I.I.5
Chen, N.J.6
Brüstle, A.7
Li, W.Y.8
Mak, T.W.9
-
46
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature. 2008;456:259-263.
-
(2008)
Nature.
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
Kishi, C.7
Kc, W.8
Carrero, J.A.9
Hunt, S.10
Stone, C.D.11
Brunt, E.M.12
Xavier, R.J.13
Sleckman, B.P.14
Li, E.15
Mizushima, N.16
Stappenbeck, T.S.17
Virgin, H.W.18
-
47
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJ, Campbell BJ, Jewell D, Simmons A. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16:90-97.
-
(2010)
Nat Med.
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
Danis, B.4
Pichulik, T.5
Allan, P.6
Ferguson, D.J.7
Campbell, B.J.8
Jewell, D.9
Simmons, A.10
-
48
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet. 2008;40:1107-1112.
-
(2008)
Nat Genet.
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
Huett, A.2
Kuballa, P.3
Chilewski, S.D.4
Landry, A.5
Goyette, P.6
Zody, M.C.7
Hall, J.L.8
Brant, S.R.9
Cho, J.H.10
Duerr, R.H.11
Silverberg, M.S.12
Taylor, K.D.13
Rioux, J.D.14
Altshuler, D.15
Daly, M.J.16
Xavier, R.J.17
|