-
2
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
3
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
-
4
-
-
43549112973
-
Epigenetic regulator polycomb group protein complexes control cell fate and cancer
-
Kanno R, Janakiraman H, Kanno M. Epigenetic regulator polycomb group protein complexes control cell fate and cancer. Cancer Sci 2008; 99: 1077-1084.
-
(2008)
Cancer Sci
, vol.99
, pp. 1077-1084
-
-
Kanno, R.1
Janakiraman, H.2
Kanno, M.3
-
5
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007; 128: 735-745.
-
(2007)
Cell
, vol.128
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
6
-
-
84856120332
-
Understanding the language of Lys36 methylation at histone H3
-
Wagner EJ, Carpenter PB. Understanding the language of Lys36 methylation at histone H3. Nat Rev Mol Cell Biol 2012; 13: 115-126.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 115-126
-
-
Wagner, E.J.1
Carpenter, P.B.2
-
7
-
-
84876888943
-
On your mark, get SET(D2), go! H3K36me3 primes DNA mismatch repair
-
Schmidt CK, Jackson SP. On your mark, get SET(D2), go! H3K36me3 primes DNA mismatch repair. Cell 2013; 153: 513-515.
-
(2013)
Cell
, vol.153
, pp. 513-515
-
-
Schmidt, C.K.1
Jackson, S.P.2
-
8
-
-
78049275346
-
Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function
-
Lucio-Eterovic AK, Singh MM, Gardner JE, Veerappan CS, Rice JC, Carpenter PB. Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function. Proc Natl Acad Sci USA 2010; 107: 16952-16957.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16952-16957
-
-
Lucio-Eterovic, A.K.1
Singh, M.M.2
Gardner, J.E.3
Veerappan, C.S.4
Rice, J.C.5
Carpenter, P.B.6
-
9
-
-
76049084596
-
Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma
-
Berdasco M, Ropero S, Setien F, Fraga MF, Lapunzina P, Losson R et al. Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma. Proc Natl Acad Sci USA 2009; 106: 21830-21835.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21830-21835
-
-
Berdasco, M.1
Ropero, S.2
Setien, F.3
Fraga, M.F.4
Lapunzina, P.5
Losson, R.6
-
10
-
-
84890569671
-
Cancer: Discrepancies in drug sensitivity
-
Weinstein JN, Lorenzi PL. Cancer: discrepancies in drug sensitivity. Nature 2013; 504: 381-383.
-
(2013)
Nature
, vol.504
, pp. 381-383
-
-
Weinstein, J.N.1
Lorenzi, P.L.2
-
11
-
-
84857377978
-
Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen
-
Mendes-Pereira AM, Sims D, Dexter T, Fenwick K, Assiotis I, Kozarewa I et al. Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen. Proc Natl Acad Sci USA 2012; 109: 2730-2735.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2730-2735
-
-
Mendes-Pereira, A.M.1
Sims, D.2
Dexter, T.3
Fenwick, K.4
Assiotis, I.5
Kozarewa, I.6
-
12
-
-
34347392874
-
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
-
Wang GG, Cai L, Pasillas MP, Kamps MP. NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nat Cell Biol 2007; 9: 804-812.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 804-812
-
-
Wang, G.G.1
Cai, L.2
Pasillas, M.P.3
Kamps, M.P.4
-
13
-
-
81355133161
-
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming
-
Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J et al. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell 2011; 44: 609-620.
-
(2011)
Mol Cell
, vol.44
, pp. 609-620
-
-
Kuo, A.J.1
Cheung, P.2
Chen, K.3
Zee, B.M.4
Kioi, M.5
Lauring, J.6
-
14
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883-892.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
15
-
-
79953143753
-
H3K36 methylation antagonizes PRC2-mediated H3K27 methylation
-
Yuan W, Xu M, Huang C, Liu N, Chen S, Zhu B. H3K36 methylation antagonizes PRC2-mediated H3K27 methylation. J Biol Chem 2011; 286: 7983-7989.
-
(2011)
J Biol Chem
, vol.286
, pp. 7983-7989
-
-
Yuan, W.1
Xu, M.2
Huang, C.3
Liu, N.4
Chen, S.5
Zhu, B.6
-
16
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 2005; 37: 391-400.
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
-
17
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R, Reuter G et al. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 2004; 18: 1251-1262.
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
-
18
-
-
84867397456
-
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20
-
Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ et al. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell 2012; 48: 28-38.
-
(2012)
Mol Cell
, vol.48
, pp. 28-38
-
-
Stender, J.D.1
Pascual, G.2
Liu, W.3
Kaikkonen, M.U.4
Do, K.5
Spann, N.J.6
-
19
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 2007; 128: 693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
20
-
-
34548827379
-
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
-
Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T et al. Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.J Cell Biol 2007; 178: 925-936.
-
(2007)
J Cell Biol
, vol.178
, pp. 925-936
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Schotta, G.4
Klatt, P.5
Jenuwein, T.6
-
21
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002; 2: 301-310.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
22
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007; 130: 1083-1094.
-
(2007)
Cell
, vol.130
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
23
-
-
34447555612
-
Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasiamutated
-
Gopal YN, Arora TS, Van Dyke MW. Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasiamutated. Chem Biol 2007; 14: 813-823.
-
(2007)
Chem Biol
, vol.14
, pp. 813-823
-
-
Gopal, Y.N.1
Arora, T.S.2
Van Dyke, M.W.3
-
24
-
-
65649091667
-
Modulation of DNA methylation by a sesquiterpene lactone parthenolide
-
Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P et al. Modulation of DNA methylation by a sesquiterpene lactone parthenolide. J Pharmacol Exp Ther 2009; 329: 505-514.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 505-514
-
-
Liu, Z.1
Liu, S.2
Xie, Z.3
Pavlovicz, R.E.4
Wu, J.5
Chen, P.6
-
25
-
-
79953212611
-
A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-kappaB and generating reactive oxygen species
-
Shanmugam R, Kusumanchi P, Appaiah H, Cheng L, Crooks P, Neelakantan S et al. A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-kappaB and generating reactive oxygen species. Int J Cancer 2011; 128: 2481-2494.
-
(2011)
Int J Cancer
, vol.128
, pp. 2481-2494
-
-
Shanmugam, R.1
Kusumanchi, P.2
Appaiah, H.3
Cheng, L.4
Crooks, P.5
Neelakantan, S.6
-
26
-
-
84875198804
-
Chromatin remodeling at DNA double-strand breaks
-
Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell 2013; 152: 1344-1354.
-
(2013)
Cell
, vol.152
, pp. 1344-1354
-
-
Price, B.D.1
D'Andrea, A.D.2
-
27
-
-
84860549923
-
Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice
-
Modak R, Das Mitra S, Krishnamoorthy P, Bhat A, Banerjee A, Gowsica BR et al. Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice. Epigenetics 2012; 7: 492-501.
-
(2012)
Epigenetics
, vol.7
, pp. 492-501
-
-
Modak, R.1
Das Mitra, S.2
Krishnamoorthy, P.3
Bhat, A.4
Banerjee, A.5
Gowsica, B.R.6
-
28
-
-
0034710539
-
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide
-
Patel NM, Nozaki S, Shortle NH, Bhat-Nakshatri P, Newton TR, Rice S et al. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide. Oncogene 2000; 19: 4159-4169.
-
(2000)
Oncogene
, vol.19
, pp. 4159-4169
-
-
Patel, N.M.1
Nozaki, S.2
Shortle, N.H.3
Bhat-Nakshatri, P.4
Newton, T.R.5
Rice, S.6
-
29
-
-
0142105387
-
Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities
-
Hoffmann A, Leung TH, Baltimore D. Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities. EMBO J 2003; 22: 5530-5539.
-
(2003)
EMBO J
, vol.22
, pp. 5530-5539
-
-
Hoffmann, A.1
Leung, T.H.2
Baltimore, D.3
-
30
-
-
0035912094
-
Repression of GADD153/CHOP by NF-kappaB: A possible cellular defense against endoplasmic reticulum stress-induced cell death
-
Nozaki S, Sledge GW Jr, Nakshatri H. Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. Oncogene 2001; 20: 2178-2185.
-
(2001)
Oncogene
, vol.20
, pp. 2178-2185
-
-
Nozaki, S.1
Sledge, G.W.2
Nakshatri, H.3
-
31
-
-
77954950168
-
Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB
-
Mott JL, Kurita S, Cazanave SC, Bronk SF, Werneburg NW, Fernandez-Zapico ME. Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB. J Cell Biochem 2010; 110: 1155-1164.
-
(2010)
J Cell Biochem
, vol.110
, pp. 1155-1164
-
-
Mott, J.L.1
Kurita, S.2
Cazanave, S.C.3
Bronk, S.F.4
Werneburg, N.W.5
Fernandez-Zapico, M.E.6
-
32
-
-
62149152072
-
Repression of hepatitis B viral gene expression by transcription factor nuclear factor-kappaB
-
Lin YC, Hsu EC, Ting LP. Repression of hepatitis B viral gene expression by transcription factor nuclear factor-kappaB. Cell Microbiol 2009; 11: 645-660.
-
(2009)
Cell Microbiol
, vol.11
, pp. 645-660
-
-
Lin, Y.C.1
Hsu, E.C.2
Ting, L.P.3
-
33
-
-
0036659130
-
Role of CXCL1 in tumorigenesis of melanoma
-
Dhawan P, Richmond A. Role of CXCL1 in tumorigenesis of melanoma. J Leukoc Biol 2002; 72: 9-18.
-
(2002)
J Leukoc Biol
, vol.72
, pp. 9-18
-
-
Dhawan, P.1
Richmond, A.2
-
34
-
-
33846828787
-
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2
-
Chua HL, Bhat-Nakshatri P, Clare SE, Morimiya A, Badve S, Nakshatri H. NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene 2007; 26: 711-724.
-
(2007)
Oncogene
, vol.26
, pp. 711-724
-
-
Chua, H.L.1
Bhat-Nakshatri, P.2
Clare, S.E.3
Morimiya, A.4
Badve, S.5
Nakshatri, H.6
-
35
-
-
79953131815
-
SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation
-
Kapoor-Vazirani P, Kagey JD, Vertino PM. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol 2011; 31: 1594-1609.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1594-1609
-
-
Kapoor-Vazirani, P.1
Kagey, J.D.2
Vertino, P.M.3
-
36
-
-
84860215207
-
Molecular mechanisms and potential functions of histone demethylases
-
Kooistra SM, Helin K. Molecular mechanisms and potential functions of histone demethylases. Nat Rev Mol Cell Biol 2012; 13: 297-311.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 297-311
-
-
Kooistra, S.M.1
Helin, K.2
-
37
-
-
70349490830
-
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB
-
Lu T, Jackson MW, Singhi AD, Kandel ES, Yang M, Zhang Y et al. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proc Natl Acad Sci USA 2009; 106: 16339-16344.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16339-16344
-
-
Lu, T.1
Jackson, M.W.2
Singhi, A.D.3
Kandel, E.S.4
Yang, M.5
Zhang, Y.6
-
38
-
-
79958797383
-
F-box protein 10, an NF-kappaB-dependent antiapoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway
-
Ge R, Wang Z, Zeng Q, Xu X, Olumi AF. F-box protein 10, an NF-kappaB-dependent antiapoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway. Cell Death Differ 2011; 18: 1184-1195.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1184-1195
-
-
Ge, R.1
Wang, Z.2
Zeng, Q.3
Xu, X.4
Olumi, A.F.5
-
39
-
-
6044240634
-
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
-
Nakshatri H, Rice SE, Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 2004; 23: 7330-7344.
-
(2004)
Oncogene
, vol.23
, pp. 7330-7344
-
-
Nakshatri, H.1
Rice, S.E.2
Bhat-Nakshatri, P.3
-
40
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013; 6: pl1.
-
(2013)
Sci Signal
, vol.6
, pp. pl1
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
-
41
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012; 2: 401-404.
-
(2012)
Cancer Discov
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
Aksoy, B.A.6
-
42
-
-
2542565666
-
Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification
-
Dyrskjot L, Kruhoffer M, Thykjaer T, Marcussen N, Jensen JL, Moller K et al. Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res 2004; 64: 4040-4048.
-
(2004)
Cancer Res
, vol.64
, pp. 4040-4048
-
-
Dyrskjot, L.1
Kruhoffer, M.2
Thykjaer, T.3
Marcussen, N.4
Jensen, J.L.5
Moller, K.6
-
43
-
-
84896339304
-
PROGgene: Gene expression based survival analysis web application for multiple cancers
-
Goswami CP, Nakshatri H. PROGgene: gene expression based survival analysis web application for multiple cancers. J Clin Bioinformatics 2013; 3: 22.
-
(2013)
J Clin Bioinformatics
, vol.3
, pp. 22
-
-
Goswami, C.P.1
Nakshatri, H.2
-
44
-
-
79151483638
-
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
-
Gyorffy B, Lanczky A, Eklund AC, Denkert C, Budczies J, Li Q et al. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res Treat 2010; 123: 725-731.
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 725-731
-
-
Gyorffy, B.1
Lanczky, A.2
Eklund, A.C.3
Denkert, C.4
Budczies, J.5
Li, Q.6
-
45
-
-
0030927167
-
Constitutive activation of NF-kappaB during progression of breast cancer to hormoneindependent growth
-
Nakshatri H, Bhat-Nakshatri P, Martin DA, Goulet RJ Jr, Sledge GW Jr. Constitutive activation of NF-kappaB during progression of breast cancer to hormoneindependent growth. Mol Cell Biol 1997; 17: 3629-3639.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
Goulet, R.J.4
Sledge, G.W.5
-
47
-
-
13944282293
-
The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; Fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells
-
Riggins RB, Zwart A, Nehra R, Clarke R. The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. Mol Cancer Ther 2005; 4: 33-41.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 33-41
-
-
Riggins, R.B.1
Zwart, A.2
Nehra, R.3
Clarke, R.4
-
48
-
-
84890909335
-
Control of apoptosis by the BCL-2 protein family: Implications for physiology and therapy
-
Czabotar PE, Lessene G, Strasser A, Adams JM. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. Nat Rev Mol Cell Biol 2013; 15: 49-63.
-
(2013)
Nat Rev Mol Cell Biol
, vol.15
, pp. 49-63
-
-
Czabotar, P.E.1
Lessene, G.2
Strasser, A.3
Adams, J.M.4
-
49
-
-
0032526951
-
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
-
Huang N, vom Baur E, Garnier JM, Lerouge T, Vonesch JL, Lutz Y et al. Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J 1998; 17: 3398-3412.
-
(1998)
EMBO J
, vol.17
, pp. 3398-3412
-
-
Huang, N.1
Vom Baur, E.2
Garnier, J.M.3
Lerouge, T.4
Vonesch, J.L.5
Lutz, Y.6
-
50
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012; 486: 400-404.
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Loo, P.4
Greenman, C.5
Wedge, D.C.6
-
51
-
-
46849115153
-
Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
-
Xie P, Tian C, An L, Nie J, Lu K, Xing G et al. Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cell Signal 2008; 20: 1671-1678.
-
(2008)
Cell Signal
, vol.20
, pp. 1671-1678
-
-
Xie, P.1
Tian, C.2
An, L.3
Nie, J.4
Lu, K.5
Xing, G.6
-
52
-
-
43249114058
-
Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms
-
Dong J, Jimi E, Zhong H, Hayden MS, Ghosh S. Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms. Genes Dev 2008; 22: 1159-1173.
-
(2008)
Genes Dev
, vol.22
, pp. 1159-1173
-
-
Dong, J.1
Jimi, E.2
Zhong, H.3
Hayden, M.S.4
Ghosh, S.5
-
53
-
-
84856304716
-
The p65 subunit of NF-kappaB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3)
-
Beauchef G, Bigot N, Kypriotou M, Renard E, Poree B, Widom R et al. The p65 subunit of NF-kappaB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3). J Biol Chem 2012; 287: 3462-3478.
-
(2012)
J Biol Chem
, vol.287
, pp. 3462-3478
-
-
Beauchef, G.1
Bigot, N.2
Kypriotou, M.3
Renard, E.4
Poree, B.5
Widom, R.6
-
54
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death [see comments]
-
Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death [see comments]. Science 1996; 274: 782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
55
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF et al. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490: 61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Koboldt, D.C.1
Fulton, R.S.2
McLellan, M.D.3
Schmidt, H.4
Kalicki-Veizer, J.5
McMichael, J.F.6
|