Case 28-2004: Newborn twins with thrombocytopenia, coagulation defects, and hepatosplenomegaly

New England Journal of Medicine

Volumn 351, Issue 11, 2004, Pages 1120-1130

  Lipton, Jeffrey M ^a,b   Westra, Sjirk ^c,d   Haverty, Carrie E ^c   Roberts, Drucilla ^c,d   Harris, Nancy Lee ^c,d  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b SCHNEIDER CHILDREN'S HOSPITAL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PERFORIN; MEMBRANE PROTEIN; PORE FORMING CYTOTOXIC PROTEIN;

ALLOIMMUNE THROMBOCYTOPENIA; BLOOD CLOTTING DISORDER; BONE MARROW BIOPSY; CASE REPORT; CLINICAL FEATURE; CONGENITAL THROMBOCYTOPENIA; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; ECHOGRAPHY; FAMILIAL DISEASE; FLOW CYTOMETRY; GENE; GENE MUTATION; GENETIC COUNSELING; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEMOPHAGOCYTIC SYNDROME; HEPATOSPLENOMEGALY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE THROMBOCYTOPENIA; LABORATORY TEST; LEUKEMIA; LIVER BIOPSY; MALE; NATURAL KILLER CELL; NEWBORN; NEWBORN INTENSIVE CARE; PATHOLOGY; PERFORIN GENE; PRIORITY JOURNAL; REVIEW; THROMBOCYTOPENIA; TWINS; ARTICLE; BLOOD ANALYSIS; BLOOD EXAMINATION; BONE MARROW; BONE MARROW TRANSPLANTATION; FATALITY; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETICS; HEPATOMEGALY; HISTIOCYTOSIS; LEUKOPENIA; LIVER; METABOLISM; MISSENSE MUTATION; MONOZYGOTIC TWINS; PHYSIOLOGY; SPLENOMEGALY; UMBILICAL CORD;

BLOOD CHEMICAL ANALYSIS; BLOOD COAGULATION DISORDERS; BONE MARROW; BONE MARROW TRANSPLANTATION; DIAGNOSIS, DIFFERENTIAL; DISEASES IN TWINS; FATAL OUTCOME; GENETIC SCREENING; HEMATOLOGIC TESTS; HEPATOMEGALY; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT, NEWBORN; KILLER CELLS, NATURAL; LEUKOPENIA; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MUTATION, MISSENSE; POLYMORPHISM, GENETIC; PORE FORMING CYTOTOXIC PROTEINS; SPLENOMEGALY; THROMBOCYTOPENIA; TWINS, MONOZYGOTIC; UMBILICAL CORD;

EID: 4444330604     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcpc049019     Document Type: Review

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