메뉴 건너뛰기




Volumn 16, Issue 4, 2015, Pages 8102-8109

Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation

Author keywords

Emodin; Interleukin (IL) 1 ; NLRP3 inflammasome; Sepsis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CRYOPYRIN; EMODIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; NIGERICIN; TUMOR NECROSIS FACTOR; URATE; ANTIINFLAMMATORY AGENT; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; ENDOTOXIN; NITRIC OXIDE DIOXYGENASE; OXYGENASE; SILICON DIOXIDE;

EID: 84927602394     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16048102     Document Type: Article
Times cited : (77)

References (23)
  • 1
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder, K.; Tschopp, J. The inflammasomes. Cell 2010, 140, 821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 2
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
    • Martinon, F.; Burns, K.; Tschopp, J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 2002, 10, 417-426.
    • (2002) Mol. Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 3
    • 84888007457 scopus 로고    scopus 로고
    • The NLRP3 inflammasome in Alzheimer’s disease
    • Tan, M.; Yu, J.; Jiang, T.; Zhu, X.; Tan, L. The NLRP3 inflammasome in Alzheimer’s disease. Mol. Neurobiol. 2013, 48, 875-882.
    • (2013) Mol. Neurobiol , vol.48 , pp. 875-882
    • Tan, M.1    Yu, J.2    Jiang, T.3    Zhu, X.4    Tan, L.5
  • 8
    • 0035793238 scopus 로고    scopus 로고
    • Immune reponses in human mesangial cells regulated by emodin from Polygonum Hypoleucum Ohwi
    • Kuo, Y.; Tsai, W.; Meng, H.; Chen, W.; Yang, L.; Lin, C. Immune reponses in human mesangial cells regulated by emodin from Polygonum Hypoleucum Ohwi. Life Sci. 2001, 68, 1271-1286.
    • (2001) Life Sci , vol.68 , pp. 1271-1286
    • Kuo, Y.1    Tsai, W.2    Meng, H.3    Chen, W.4    Yang, L.5    Lin, C.6
  • 9
    • 27944489622 scopus 로고    scopus 로고
    • Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn. Rubia cordifolia Linn. and Lantana camara Linn.: Isolation of emodin and physcion as active antibacterial agents
    • Basu, S.; Ghosh, A.; Hazra, B. Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn.: Isolation of emodin and physcion as active antibacterial agents. Phytother. Res. 2005, 19, 888-894.
    • (2005) Phytother. Res , vol.19 , pp. 888-894
    • Basu, S.1    Ghosh, A.2    Hazra, B.3
  • 10
    • 0033979253 scopus 로고    scopus 로고
    • Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin
    • Sato, M.; Maulik, G.; Bagchi, D.; Das, D.K. Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin. Free Radic. Res. 2000, 32, 135-144.
    • (2000) Free Radic. Res , vol.32 , pp. 135-144
    • Sato, M.1    Maulik, G.2    Bagchi, D.3    Das, D.K.4
  • 11
    • 20444505248 scopus 로고    scopus 로고
    • Emodin Induces Apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
    • Su, Y.; Chang, H.; Shyue, S.; Hsu, S. Emodin Induces Apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem. Pharmacol. 2005, 70, 229-241.
    • (2005) Biochem. Pharmacol , vol.70 , pp. 229-241
    • Su, Y.1    Chang, H.2    Shyue, S.3    Hsu, S.4
  • 12
    • 80255123790 scopus 로고    scopus 로고
    • Emodin, a naturally occurring anthraquinone derivative, suppresses LgE-mediated anaphylactic reaction and mast cell activation
    • Lu, Y.; Yang, J.H.; Li, X.; Hwangbo, K.; Hwang, S.; Taketomi, Y.; Murakami, M.; Chang, Y.; Kim, C.; Son, J. Emodin, a naturally occurring anthraquinone derivative, suppresses LgE-mediated anaphylactic reaction and mast cell activation. Biochem. Pharmacol. 2011, 82, 1700-1708.
    • (2011) Biochem. Pharmacol , vol.82 , pp. 1700-1708
    • Lu, Y.1    Yang, J.H.2    Li, X.3    Hwangbo, K.4    Hwang, S.5    Taketomi, Y.6    Murakami, M.7    Chang, Y.8    Kim, C.9    Son, J.10
  • 13
    • 84893718553 scopus 로고    scopus 로고
    • Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling
    • Kim, D.; Kang, T.; Shim, D.; Sun, X.; Han, J.; Ji, Y.; Kim, T.; Koppula, S.; Lee, K. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur. J. Pharmacol. 2014, 723, 501-506.
    • (2014) Eur. J. Pharmacol , vol.723 , pp. 501-506
    • Kim, D.1    Kang, T.2    Shim, D.3    Sun, X.4    Han, J.5    Ji, Y.6    Kim, T.7    Koppula, S.8    Lee, K.9
  • 14
    • 35348975068 scopus 로고    scopus 로고
    • Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium
    • Wu, Y.; Tu, X.; Lin, G.; Xia, H.; Huang, H.; Wan, J.; Cheng, Z.; Liu, M.; Chen, G.; Zhang, H. Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium. Life Sci. 2007, 81, 1332-1338.
    • (2007) Life Sci , vol.81 , pp. 1332-1338
    • Wu, Y.1    Tu, X.2    Lin, G.3    Xia, H.4    Huang, H.5    Wan, J.6    Cheng, Z.7    Liu, M.8    Chen, G.9    Zhang, H.10
  • 15
    • 48149106497 scopus 로고    scopus 로고
    • Exploration of emodin to treat α-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway
    • Ding, Y.; Zhao, L.; Mei, H.; Zhang, S.; Huang, Z.; Duan, Y.; Ye, P. Exploration of emodin to treat α-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur. J. Pharmacol. 2008, 590, 377-386.
    • (2008) Eur. J. Pharmacol , vol.590 , pp. 377-386
    • Ding, Y.1    Zhao, L.2    Mei, H.3    Zhang, S.4    Huang, Z.5    Duan, Y.6    Ye, P.7
  • 16
    • 15444356379 scopus 로고    scopus 로고
    • Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells
    • Kumar, A.; Dhawan, S.; Aggarwal, B.B. Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells. Oncogene 1998, 17, 913-918.
    • (1998) Oncogene , vol.17 , pp. 913-918
    • Kumar, A.1    Dhawan, S.2    Aggarwal, B.B.3
  • 18
    • 69549119940 scopus 로고    scopus 로고
    • Molecular mechanisms involved in inflammasome activation
    • Bryant, C.; Fitzgerald, K.A. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 2009, 19, 455-464.
    • (2009) Trends Cell Biol , vol.19 , pp. 455-464
    • Bryant, C.1    Fitzgerald, K.A.2
  • 19
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou, R.; Yazdi, A.S.; Menu, P.; Tschopp, J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469, 221-225.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 23
    • 84889094215 scopus 로고    scopus 로고
    • Lysimachia clethroides Duby extract attenuates inflammatory response in Raw 264.7 macrophages stimulated with lipopolysaccharide and in acute lung injury mouse model
    • Shim, D.; Han, J.; Sun, X.; Jang, C.; Koppula, S.; Kim, T.; Kang, T.; Lee, K. Lysimachia clethroides Duby extract attenuates inflammatory response in Raw 264.7 macrophages stimulated with lipopolysaccharide and in acute lung injury mouse model. J. Ethnopharmacol. 2013, 150, 1007-1015.
    • (2013) J. Ethnopharmacol , vol.150 , pp. 1007-1015
    • Shim, D.1    Han, J.2    Sun, X.3    Jang, C.4    Koppula, S.5    Kim, T.6    Kang, T.7    Lee, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.