-
1
-
-
77950362382
-
The inflammasomes
-
Schroder, K.; Tschopp, J. The inflammasomes. Cell 2010, 140, 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
2
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
Martinon, F.; Burns, K.; Tschopp, J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 2002, 10, 417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
3
-
-
84888007457
-
The NLRP3 inflammasome in Alzheimer’s disease
-
Tan, M.; Yu, J.; Jiang, T.; Zhu, X.; Tan, L. The NLRP3 inflammasome in Alzheimer’s disease. Mol. Neurobiol. 2013, 48, 875-882.
-
(2013)
Mol. Neurobiol
, vol.48
, pp. 875-882
-
-
Tan, M.1
Yu, J.2
Jiang, T.3
Zhu, X.4
Tan, L.5
-
4
-
-
84885863093
-
Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue
-
Esser, N.; L’homme, L.; de Roover, A.; Kohnen, L.; Scheen, A.J.; Moutschen, M.; Piette, J.; Legrand-Poels, S.; Paquot, N. Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue. Diabetologia 2013, 56, 2487-2497.
-
(2013)
Diabetologia
, vol.56
, pp. 2487-2497
-
-
Esser, N.1
L’homme, L.2
de Roover, A.3
Kohnen, L.4
Scheen, A.J.5
Moutschen, M.6
Piette, J.7
Legrand-Poels, S.8
Paquot, N.9
-
5
-
-
84891829365
-
NLRP3 Inflammasome is activated in mononuclear blood cells from patients with major depressive disorder
-
Alcocer-Gómez, E.; de Miguel, M.; Casas-Barquero, N.; Núñez-Vasco, J.; Sánchez-Alcazar, J.A.; Fernández-Rodríguez, A.; Cordero, M.D. NLRP3 Inflammasome is activated in mononuclear blood cells from patients with major depressive disorder. Brain Behav. Immun. 2014, 36, 111-117.
-
(2014)
Brain Behav. Immun
, vol.36
, pp. 111-117
-
-
Alcocer-Gómez, E.1
de Miguel, M.2
Casas-Barquero, N.3
Núñez-Vasco, J.4
Sánchez-Alcazar, J.A.5
Fernández-Rodríguez, A.6
Cordero, M.D.7
-
6
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar, B.; Youm, Y.; Ravussin, A.; Galgani, J.E.; Stadler, K.; Mynatt, R.L.; Ravussin, E.; Stephens, J.M.; Dixit, V.D. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat. Med. 2011, 17, 179-188.
-
(2011)
Nat. Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
7
-
-
84894451166
-
NLRP3 inflammasome is activated in fibromyalgia: The effect of coenzyme Q10
-
Cordero, M.D.; Alcocer-Gómez, E.; Culic, O.; Carrión, A.M.; de Miguel, M.; Díaz-Parrado, E.; Pérez-Villegas, E.M.; Bullón, P.; Battino, M.; Sánchez-Alcazar, J.A. NLRP3 inflammasome is activated in fibromyalgia: The effect of coenzyme Q10. Antioxid. Redox Signal. 2014, 20, 1169-1180.
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 1169-1180
-
-
Cordero, M.D.1
Alcocer-Gómez, E.2
Culic, O.3
Carrión, A.M.4
de Miguel, M.5
Díaz-Parrado, E.6
Pérez-Villegas, E.M.7
Bullón, P.8
Battino, M.9
Sánchez-Alcazar, J.A.10
-
8
-
-
0035793238
-
Immune reponses in human mesangial cells regulated by emodin from Polygonum Hypoleucum Ohwi
-
Kuo, Y.; Tsai, W.; Meng, H.; Chen, W.; Yang, L.; Lin, C. Immune reponses in human mesangial cells regulated by emodin from Polygonum Hypoleucum Ohwi. Life Sci. 2001, 68, 1271-1286.
-
(2001)
Life Sci
, vol.68
, pp. 1271-1286
-
-
Kuo, Y.1
Tsai, W.2
Meng, H.3
Chen, W.4
Yang, L.5
Lin, C.6
-
9
-
-
27944489622
-
Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn. Rubia cordifolia Linn. and Lantana camara Linn.: Isolation of emodin and physcion as active antibacterial agents
-
Basu, S.; Ghosh, A.; Hazra, B. Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn.: Isolation of emodin and physcion as active antibacterial agents. Phytother. Res. 2005, 19, 888-894.
-
(2005)
Phytother. Res
, vol.19
, pp. 888-894
-
-
Basu, S.1
Ghosh, A.2
Hazra, B.3
-
10
-
-
0033979253
-
Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin
-
Sato, M.; Maulik, G.; Bagchi, D.; Das, D.K. Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin. Free Radic. Res. 2000, 32, 135-144.
-
(2000)
Free Radic. Res
, vol.32
, pp. 135-144
-
-
Sato, M.1
Maulik, G.2
Bagchi, D.3
Das, D.K.4
-
11
-
-
20444505248
-
Emodin Induces Apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
-
Su, Y.; Chang, H.; Shyue, S.; Hsu, S. Emodin Induces Apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem. Pharmacol. 2005, 70, 229-241.
-
(2005)
Biochem. Pharmacol
, vol.70
, pp. 229-241
-
-
Su, Y.1
Chang, H.2
Shyue, S.3
Hsu, S.4
-
12
-
-
80255123790
-
Emodin, a naturally occurring anthraquinone derivative, suppresses LgE-mediated anaphylactic reaction and mast cell activation
-
Lu, Y.; Yang, J.H.; Li, X.; Hwangbo, K.; Hwang, S.; Taketomi, Y.; Murakami, M.; Chang, Y.; Kim, C.; Son, J. Emodin, a naturally occurring anthraquinone derivative, suppresses LgE-mediated anaphylactic reaction and mast cell activation. Biochem. Pharmacol. 2011, 82, 1700-1708.
-
(2011)
Biochem. Pharmacol
, vol.82
, pp. 1700-1708
-
-
Lu, Y.1
Yang, J.H.2
Li, X.3
Hwangbo, K.4
Hwang, S.5
Taketomi, Y.6
Murakami, M.7
Chang, Y.8
Kim, C.9
Son, J.10
-
13
-
-
84893718553
-
Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling
-
Kim, D.; Kang, T.; Shim, D.; Sun, X.; Han, J.; Ji, Y.; Kim, T.; Koppula, S.; Lee, K. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur. J. Pharmacol. 2014, 723, 501-506.
-
(2014)
Eur. J. Pharmacol
, vol.723
, pp. 501-506
-
-
Kim, D.1
Kang, T.2
Shim, D.3
Sun, X.4
Han, J.5
Ji, Y.6
Kim, T.7
Koppula, S.8
Lee, K.9
-
14
-
-
35348975068
-
Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium
-
Wu, Y.; Tu, X.; Lin, G.; Xia, H.; Huang, H.; Wan, J.; Cheng, Z.; Liu, M.; Chen, G.; Zhang, H. Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium. Life Sci. 2007, 81, 1332-1338.
-
(2007)
Life Sci
, vol.81
, pp. 1332-1338
-
-
Wu, Y.1
Tu, X.2
Lin, G.3
Xia, H.4
Huang, H.5
Wan, J.6
Cheng, Z.7
Liu, M.8
Chen, G.9
Zhang, H.10
-
15
-
-
48149106497
-
Exploration of emodin to treat α-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway
-
Ding, Y.; Zhao, L.; Mei, H.; Zhang, S.; Huang, Z.; Duan, Y.; Ye, P. Exploration of emodin to treat α-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur. J. Pharmacol. 2008, 590, 377-386.
-
(2008)
Eur. J. Pharmacol
, vol.590
, pp. 377-386
-
-
Ding, Y.1
Zhao, L.2
Mei, H.3
Zhang, S.4
Huang, Z.5
Duan, Y.6
Ye, P.7
-
16
-
-
15444356379
-
Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells
-
Kumar, A.; Dhawan, S.; Aggarwal, B.B. Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells. Oncogene 1998, 17, 913-918.
-
(1998)
Oncogene
, vol.17
, pp. 913-918
-
-
Kumar, A.1
Dhawan, S.2
Aggarwal, B.B.3
-
17
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri, T.; Wu, J.; Yu, J.; Datta, P.; Miller, B.; Jankowski, W.; Rosenberg, S.; Zhang, J.; Alnemri, E. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007, 14, 1590-1604.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.9
-
18
-
-
69549119940
-
Molecular mechanisms involved in inflammasome activation
-
Bryant, C.; Fitzgerald, K.A. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 2009, 19, 455-464.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 455-464
-
-
Bryant, C.1
Fitzgerald, K.A.2
-
19
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R.; Yazdi, A.S.; Menu, P.; Tschopp, J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469, 221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
20
-
-
84887897805
-
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
-
Hara, H.; Tsuchiya, K.; Kawamura, I.; Fang, R.; Hernandez-Cuellar, E.; Shen, Y.; Mizuguchi, J.; Schweighoffer, E.; Tybulewicz, V.; Mitsuyama, M. Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity. Nat. Immunol. 2013, 14, 1247-1255.
-
(2013)
Nat. Immunol
, vol.14
, pp. 1247-1255
-
-
Hara, H.1
Tsuchiya, K.2
Kawamura, I.3
Fang, R.4
Hernandez-Cuellar, E.5
Shen, Y.6
Mizuguchi, J.7
Schweighoffer, E.8
Tybulewicz, V.9
Mitsuyama, M.10
-
21
-
-
30844432876
-
Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization
-
Yu, J.; Wu, J.; Zhang, Z.; Datta, P.; Ibrahimi, I.; Taniguchi, S.; Sagara, J.; Fernandes-Alnemri, T.; Alnemri, E. Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization. Cell Death Differ. 2006, 13, 236-249.
-
(2006)
Cell Death Differ
, vol.13
, pp. 236-249
-
-
Yu, J.1
Wu, J.2
Zhang, Z.3
Datta, P.4
Ibrahimi, I.5
Taniguchi, S.6
Sagara, J.7
Fernandes-Alnemri, T.8
Alnemri, E.9
-
22
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S.; Weiss, D.S.; Newton, K.; McBride, J.; O'Rourke, K.; Roose-Girma, M.; Lee, W.P.; Weinrauch, Y.; Monack, D.M.; Dixit, V.M. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006, 440, 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
23
-
-
84889094215
-
Lysimachia clethroides Duby extract attenuates inflammatory response in Raw 264.7 macrophages stimulated with lipopolysaccharide and in acute lung injury mouse model
-
Shim, D.; Han, J.; Sun, X.; Jang, C.; Koppula, S.; Kim, T.; Kang, T.; Lee, K. Lysimachia clethroides Duby extract attenuates inflammatory response in Raw 264.7 macrophages stimulated with lipopolysaccharide and in acute lung injury mouse model. J. Ethnopharmacol. 2013, 150, 1007-1015.
-
(2013)
J. Ethnopharmacol
, vol.150
, pp. 1007-1015
-
-
Shim, D.1
Han, J.2
Sun, X.3
Jang, C.4
Koppula, S.5
Kim, T.6
Kang, T.7
Lee, K.8
|