Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs

Journal of Biological Chemistry

Volumn 290, Issue 15, 2015, Pages 9428-9441

  Marudamuthu, Amarnath S ^a   Shetty, Shwetha K ^a   Bhandary, Yashodhar P ^a   Karandashova, Sophia ^a   Thompson, Michael ^b   Sathish, Venkatachalem ^b   Florova, Galina ^a   Hogan, Taryn B ^a   Pabelick, Christina M ^b   Prakash, Y S ^b   Tsukasaki, Yoshikazu ^a   Fu, Jian ^c   Ikebe, Mitsuo ^a   Idell, Steven ^a   Shetty, Sreerama ^a  

^a University of Texas Health Science Center   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; BIOLOGICAL ORGANS; CELL CULTURE; CHEMICAL ACTIVATION; COLLAGEN; DISEASE CONTROL; MAMMALS; MUSCLE;

EPITHELIAL CELLS; IDIOPATHIC PULMONARY FIBROSIS; LUNG FIBROBLASTS; PLASMINOGEN ACTIVATOR INHIBITOR-1; PLASMINOGEN ACTIVATORS; PULMONARY FIBROSIS; SMOOTH MUSCLE ACTINS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA);

FIBROBLASTS;

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; UROKINASE; UROKINASE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FIBROSIS; LUNG FUNCTION TEST; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CONFOCAL MICROSCOPY; EPITHELIUM CELL; FIBROSING ALVEOLITIS; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE; WESTERN BLOTTING;

ADENOVIRIDAE; MURINAE; MUS;

ACTINS; ANIMALS; APOPTOSIS; BLEOMYCIN; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; EPITHELIAL CELLS; FIBROBLASTS; GENE EXPRESSION; IDIOPATHIC PULMONARY FIBROSIS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MUSCLE, SMOOTH; PLASMINOGEN ACTIVATOR INHIBITOR 1; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84927154495     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.601815     Document Type: Article

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