Resistance to Fas-mediated apoptosis in human lung fibroblast

European Respiratory Journal

Volumn 20, Issue 2, 2002, Pages 359-368

  Tanaka, T ^a   Yoshimi, M ^a   Maeyama, T ^a   Hagimoto, N ^a   Kuwano, K ^a   Hara, N ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Fas; Fibroblast; Pulmonary fibrosis

Indexed keywords

APOPTOSIS INHIBITOR; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOHEXIMIDE; FAS ANTIBODY; FAS ANTIGEN; FLICE INHIBITORY PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; CARRIER PROTEIN; CFLAR PROTEIN, HUMAN; ENZYME INHIBITOR; PROTEIN; SIGNAL PEPTIDE;

APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG PARENCHYMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; X CHROMOSOME; ADULT; AGED; CELL CYCLE; DRUG EFFECT; FIBROBLAST; IN VITRO STUDY; LUNG; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; AGED; ANTIGENS, CD95; APOPTOSIS; CARRIER PROTEINS; CELL CYCLE; CELL LINE; ENZYME INHIBITORS; FIBROBLASTS; HUMAN; IN VITRO; LUNG; MIDDLE AGE; PROTEINS; PULMONARY FIBROSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MIDDLE AGED;

EID: 0035989812     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.02.00252602     Document Type: Article

References (36)

1. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
2. Molecular cloning and expression of Fas ligand, a novel member of the tumor necrosis factor family
3. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C
4. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes
5. Fas expression in pulmonary alveolar type II cells
6. Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: A major role for inositol 1,4,5-triphosphate
7. The involvement of Fas-Fas ligand pathway in fibrosing lung diseases
8. P21Wafl/Cip1/Sdil and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis
9. Apoptosis and expression of Fas/Fas ligand pathway in bleomycin-induced pulmonary fibrosis in mice
10. Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen
11. Bcl-2 and the regulation of programmed cell death
12. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of cell death
13. Bcl-2 functions in an antioxidant pathway to prevent apoptosis
14. Effect of bcl-2 on Fas-mediated cell death
15. Caspases: Enemies within
16. X-linked IAP is a direct inhibitor of cell-death proteases
17. WAF1 and IAP gene family ILP
18. FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
19. Viral FLICE-inhibitory proteins (FLIPS) prevent apoptosis induced by death receptors
20. Inhibition of death receptor signals by cellular FLIP
21. Fas-mediated apoptosis of proliferating, transiently growth arrested, and senescent normal human fibroblasts
22. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
23. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells
24. Anti-fas induces apoptosis and proloferation in human dermal fibroblasts: Differences between foreskin and adult fibroblasts
25. Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor
26. Translation inhibition in apoptosis. Caspase dependent PKR activation and eIF2-a phosphorylation
27. Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis
28. Induction of interleukin-8 secretion and apoptosis in bronchiolar epithelial cells by Fas ligation
29. Expression of bcl-2 protein and APO-1 (Fas antigen) in the lung tissue from patients with idiopathic pulmonary fibrosis
30. Tumor necrosis factor-α-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2
31. Mitochondria and apoptosis
32. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
33. IAPs block apoptosic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
34. Re-population of denuded tracheal grafts with normal, pre-neoplastic and neoplastic epithelial cell populations
35. Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro
36. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung