Redox-Induced Src kinase and Caveolin-1 signaling in TGF-β1-Initiated SMAD2/3 activation and PAI-1 expression

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Samarakoon, Rohan ^a   Chitnis, Subhanir S ^a   Higgins, Stephen P ^a   Higgins, Craig E ^a   Krepinsky, Joan C ^b   Higgins, Paul J ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE FYN; PROTEIN KINASE P60; PROTEIN KINASE YES; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2C; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CAROTID ARTERY; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN TISSUE; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WILD TYPE; ANIMAL; ANIMAL EMBRYO; AORTA; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; ENZYME IMMUNOASSAY; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; AORTA; BLOTTING, WESTERN; CAVEOLIN 1; CELLS, CULTURED; EMBRYO, MAMMALIAN; FIBROBLASTS; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; OXIDATION-REDUCTION; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79960882925     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022896     Document Type: Article

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