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Volumn 2015, Issue , 2015, Pages

Cellular mechanisms underlying eosinophilic and neutrophilic airway inflammation in asthma

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CORTICOSTEROID; CYTOKINE; MEPOLIZUMAB; RESLIZUMAB;

EID: 84927126791     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/879783     Document Type: Review
Times cited : (184)

References (86)
  • 1
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • G. P. Anderson, "Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease, " The Lancet, vol. 372, no. 9643, pp. 1107-1119, 2008.
    • (2008) The Lancet , vol.372 , Issue.9643 , pp. 1107-1119
    • Anderson, G.P.1
  • 3
    • 73549109887 scopus 로고    scopus 로고
    • Is the prevalence of asthma declining? Systematic review of epidemiological studies
    • C. Anandan, U. Nurmatov, O.C. P. Van Schayck, and A. Sheikh, "Is the prevalence of asthma declining? Systematic review of epidemiological studies, " Allergy, vol. 65, no. 2, pp. 152-167, 2010.
    • (2010) Allergy , vol.65 , Issue.2 , pp. 152-167
    • Anandan, C.1    Nurmatov, U.2    Van Schayck, O.C.P.3    Sheikh, A.4
  • 4
    • 2342590065 scopus 로고    scopus 로고
    • The global burden of asthma: Executive summary of the GINA dissemination committee report
    • M. Masoli, D. Fabian, S. Holt, and R. Beasley, "The global burden of asthma: executive summary of the GINA dissemination committee report, " Allergy, vol. 59, no. 5, pp. 469-478, 2004.
    • (2004) Allergy , vol.59 , Issue.5 , pp. 469-478
    • Masoli, M.1    Fabian, D.2    Holt, S.3    Beasley, R.4
  • 5
    • 84914177602 scopus 로고    scopus 로고
    • Asthma: Still a promising future?
    • P. Chanez and M. Humbert, "Asthma: still a promising future?" European Respiratory Review, vol. 23, no. 134, pp. 405-407, 2014.
    • (2014) European Respiratory Review , vol.23 , Issue.134 , pp. 405-407
    • Chanez, P.1    Humbert, M.2
  • 6
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • P. J. Barnes, "The cytokine network in asthma and chronic obstructive pulmonary disease, " Journal of Clinical Investigation, vol. 118, no. 11, pp. 3546-3556, 2008.
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.11 , pp. 3546-3556
    • Barnes, P.J.1
  • 7
    • 84887995285 scopus 로고    scopus 로고
    • Complex phenotypes in asthma: Current definitions
    • S. E. Wenzel, "Complex phenotypes in asthma: current definitions, " Pulmonary Pharmacology & Therapeutics, vol. 26, no. 6, pp. 710-715, 2013.
    • (2013) Pulmonary Pharmacology & Therapeutics , vol.26 , Issue.6 , pp. 710-715
    • Wenzel, S.E.1
  • 9
    • 84922273103 scopus 로고    scopus 로고
    • The immunology of asthma
    • B. N. Lambrecht and H. Hammad, "The immunology of asthma, " Nature Immunology, vol. 16, no. 1, pp. 45-56, 2014.
    • (2014) Nature Immunology , vol.16 , Issue.1 , pp. 45-56
    • Lambrecht, B.N.1    Hammad, H.2
  • 10
    • 84882238835 scopus 로고    scopus 로고
    • Eosinophilic airway inflammation in nonallergic asthma
    • G. G. Brusselle, T.Maes, and K. R. Bracke, "Eosinophilic airway inflammation in nonallergic asthma, " Nature Medicine, vol. 19, no. 8, pp. 977-979, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.8 , pp. 977-979
    • Brusselle, G.G.1    Maes, T.2    Bracke, K.R.3
  • 11
    • 84902352161 scopus 로고    scopus 로고
    • The cell biology of asthma
    • D. J. Erle and D. Sheppard, "The cell biology of asthma, " The Journal of Cell Biology, vol. 205, no. 5, pp. 621-631, 2014.
    • (2014) The Journal of Cell Biology , vol.205 , Issue.5 , pp. 621-631
    • Erle, D.J.1    Sheppard, D.2
  • 15
    • 84926299974 scopus 로고    scopus 로고
    • Mode of dendritic cell activation: The decisive hand in Th2/Th17 cell differentiation, Implications in asthma severity?
    • H. Vroman, B. van den Blink, and M. Kool, "Mode of dendritic cell activation: The decisive hand in Th2/Th17 cell differentiation. Implications in asthma severity?" Immunobiology, vol. 220, no. 2, pp. 254-261, 2015.
    • (2015) Immunobiology , vol.220 , Issue.2 , pp. 254-261
    • Vroman, H.1    Van Den Blink, B.2    Kool, M.3
  • 16
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • H. Hammad, M. Chieppa, F. Perros, M. A. Willart, R. N. Germain, and B. N. Lambrecht, "House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells, " Nature Medicine, vol. 15, no. 4, pp. 410-416, 2009.
    • (2009) Nature Medicine , vol.15 , Issue.4 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 18
    • 64149099035 scopus 로고    scopus 로고
    • Dust mites' dirty dealings in the lung
    • C. M. Lloyd, "Dust mites' dirty dealings in the lung, " Nature Medicine, vol. 15, no. 4, pp. 366-367, 2009.
    • (2009) Nature Medicine , vol.15 , Issue.4 , pp. 366-367
    • Lloyd, C.M.1
  • 19
    • 84883187953 scopus 로고    scopus 로고
    • Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation
    • Z. Su, J. Lin, F. Lu et al., "Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation, " Mucosal Immunology, vol. 6, no. 5, pp. 921-930, 2013.
    • (2013) Mucosal Immunology , vol.6 , Issue.5 , pp. 921-930
    • Su, Z.1    Lin, J.2    Lu, F.3
  • 20
    • 34250216374 scopus 로고    scopus 로고
    • T-cell co-stimulatory molecules: Their role in allergic immune reactions
    • T. Kallinich, K. C. Beler, U.Wahn, P. Stock, and E. Hamelmann, "T-cell co-stimulatory molecules: Their role in allergic immune reactions, " European Respiratory Journal, vol. 29, no. 6, pp. 1246- 1255, 2007.
    • (2007) European Respiratory Journal , vol.29 , Issue.6 , pp. 1246-1255
    • Kallinich, T.1    Beler, K.C.2    Wahn, U.3    Stock, P.4    Hamelmann, E.5
  • 21
    • 38649090061 scopus 로고    scopus 로고
    • Immunological decision-making: How does the immune system decide to mount a helper T-cell response?
    • G. E. Kaiko, J. C. Horvat, K. W. Beagley, and P. M. Hansbro, "Immunological decision-making: how does the immune system decide to mount a helper T-cell response?" Immunology, vol. 123, no. 3, pp. 326-338, 2008.
    • (2008) Immunology , vol.123 , Issue.3 , pp. 326-338
    • Kaiko, G.E.1    Horvat, J.C.2    Beagley, K.W.3    Hansbro, P.M.4
  • 23
    • 78650804976 scopus 로고    scopus 로고
    • New insights into the generation of Th2 immunity and potential therapeutic targets for the treatment of asthma
    • G. E. Kaiko and P. S. Foster, "New insights into the generation of Th2 immunity and potential therapeutic targets for the treatment of asthma, " Current Opinion in Allergy and Clinical Immunology, vol. 11, no. 1, pp. 39-45, 2011.
    • (2011) Current Opinion in Allergy and Clinical Immunology , vol.11 , Issue.1 , pp. 39-45
    • Kaiko, G.E.1    Foster, P.S.2
  • 24
    • 84873408369 scopus 로고    scopus 로고
    • Targeting eosinophils in allergy, inflammation and beyond
    • P. C. Fulkerson and M. E. Rothenberg, "Targeting eosinophils in allergy, inflammation and beyond, " Nature Reviews Drug Discovery, vol. 12, no. 2, pp. 117-129, 2013.
    • (2013) Nature Reviews Drug Discovery , vol.12 , Issue.2 , pp. 117-129
    • Fulkerson, P.C.1    Rothenberg, M.E.2
  • 25
    • 77952753062 scopus 로고    scopus 로고
    • Eosinophil survival and apoptosis in health and disease
    • Y. M. Park and B. S. Bochner, "Eosinophil survival and apoptosis in health and disease, " Allergy, Asthma and Immunology Research, vol. 2, no. 2, pp. 87-101, 2010.
    • (2010) Allergy, Asthma and Immunology Research , vol.2 , Issue.2 , pp. 87-101
    • Park, Y.M.1    Bochner, B.S.2
  • 26
    • 84905669404 scopus 로고    scopus 로고
    • Eosinophils in the lung-modulating apoptosis and efferocytosis in airway inflammation
    • J. M. Felton, C. D. Lucas, A. G. Rossi, and I. Dransfield, "Eosinophils in the lung-modulating apoptosis and efferocytosis in airway inflammation, " Frontiers in Immunology, vol. 5, article 302, 2014.
    • (2014) Frontiers in Immunology , vol.5
    • Felton, J.M.1    Lucas, C.D.2    Rossi, A.G.3    Dransfield, I.4
  • 30
    • 84910663190 scopus 로고    scopus 로고
    • Keymediators in the immunopathogenesis of allergic asthma
    • S. Hall and D. K. Agrawal, "Keymediators in the immunopathogenesis of allergic asthma, " International Immunopharmacology, vol. 23, no. 1, pp. 316-329, 2014.
    • (2014) International Immunopharmacology , vol.23 , Issue.1 , pp. 316-329
    • Hall, S.1    Agrawal, D.K.2
  • 31
    • 4544274172 scopus 로고    scopus 로고
    • A critical role for eosinophils in allergic airways remodeling
    • A. A. Humbles, C. M. Lloyd, S. J. McMillan et al., "A critical role for eosinophils in allergic airways remodeling, " Science, vol. 305, no. 5691, pp. 1776-1779, 2004.
    • (2004) Science , vol.305 , Issue.5691 , pp. 1776-1779
    • Humbles, A.A.1    Lloyd, C.M.2    McMillan, S.J.3
  • 32
    • 84868608435 scopus 로고    scopus 로고
    • The expanding role(s) of eosinophils in health and disease
    • E. A. Jacobsen, R. A. Helmers, J. J. Lee, and N. A. Lee, "The expanding role(s) of eosinophils in health and disease, " Blood, vol. 120, no. 19, pp. 3882-3890, 2012.
    • (2012) Blood , vol.120 , Issue.19 , pp. 3882-3890
    • Jacobsen, E.A.1    Helmers, R.A.2    Lee, J.J.3    Lee, N.A.4
  • 34
    • 84907983938 scopus 로고    scopus 로고
    • Innate lymphoid cells in inflammation and immunity
    • A. N. McKenzie, H. Spits, and G. Eberl, "Innate lymphoid cells in inflammation and immunity, " Immunity, vol. 41, no. 3, pp. 366-374, 2014.
    • (2014) Immunity , vol.41 , Issue.3 , pp. 366-374
    • McKenzie, A.N.1    Spits, H.2    Eberl, G.3
  • 35
    • 84897402119 scopus 로고    scopus 로고
    • Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologousmolecule expressed on Tα2 cells
    • L. Xue, M. Salimi, I. Panse et al., "Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologousmolecule expressed on Tα2 cells, " Journal of Allergy and Clinical Immunology, vol. 133, no. 4, pp. 11847- 11947, 2014.
    • (2014) Journal of Allergy and Clinical Immunology , vol.133 , Issue.4 , pp. 11847-11947
    • Xue, L.1    Salimi, M.2    Panse, I.3
  • 36
    • 80054889051 scopus 로고    scopus 로고
    • Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
    • J. M. Mjösberg, S. Trifari, N. K. Crellin et al., "Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161, " Nature Immunology, vol. 12, no. 11, pp. 1055-1062, 2011.
    • (2011) Nature Immunology , vol.12 , Issue.11 , pp. 1055-1062
    • Mjösberg, J.M.1    Trifari, S.2    Crellin, N.K.3
  • 37
    • 84906822605 scopus 로고    scopus 로고
    • Enhanced innate type 2 immune response in peripheral blood from patients with asthma
    • K.R. Bartemes, G.M. Kephart, S. J. Fox, and H. Kita, "Enhanced innate type 2 immune response in peripheral blood from patients with asthma, " The Journal of Allergy and Clinical Immunology, vol. 134, no. 3, pp. 6714-6784, 2014.
    • (2014) The Journal of Allergy and Clinical Immunology , vol.134 , Issue.3 , pp. 6714-6784
    • Bartemes, K.R.1    Kephart, G.M.2    Fox, S.J.3    Kita, H.4
  • 38
    • 79959380307 scopus 로고    scopus 로고
    • Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
    • Y.-J. Chang, H. Y. Kim, L. A. Albacker et al., "Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity, " Nature Immunology, vol. 12, no. 7, pp. 631-638, 2011.
    • (2011) Nature Immunology , vol.12 , Issue.7 , pp. 631-638
    • Chang, Y.-J.1    Kim, H.Y.2    Albacker, L.A.3
  • 39
    • 84863011729 scopus 로고    scopus 로고
    • IL-33-responsive lineage-CD25+CD44hα lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs
    • K. R. Bartemes, K. Iijima, T. Kobayashi, G. M. Kephart, A. N. McKenzie, and H. Kita, "IL-33-responsive lineage-CD25+CD44hα lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs, " Journal of Immunology, vol. 188, no. 3, pp. 1503-1513, 2012.
    • (2012) Journal of Immunology , vol.188 , Issue.3 , pp. 1503-1513
    • Bartemes, K.R.1    Iijima, K.2    Kobayashi, T.3    Kephart, G.M.4    McKenzie, A.N.5    Kita, H.6
  • 40
    • 0036734152 scopus 로고    scopus 로고
    • Multipronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4
    • B. D. Levy, G. T. de Sanctis, P. R. Devchand et al., "Multipronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4, " Nature Medicine, vol. 8, no. 9, pp. 1018- 1023, 2002.
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 1018-1023
    • Levy, B.D.1    Sanctis, G.T.D.2    Devchand, P.R.3
  • 41
    • 84890794285 scopus 로고    scopus 로고
    • Eosinophil apoptosis as a therapeutic target in allergic asthma
    • P. Ilmarinen and H. Kankaanranta, "Eosinophil apoptosis as a therapeutic target in allergic asthma, " Basic & Clinical Pharmacology & Toxicology, vol. 114, no. 1, pp. 109-117, 2014.
    • (2014) Basic & Clinical Pharmacology & Toxicology , vol.114 , Issue.1 , pp. 109-117
    • Ilmarinen, P.1    Kankaanranta, H.2
  • 42
    • 0034693075 scopus 로고    scopus 로고
    • Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone
    • X. Zhang, E. Moilanen, and H. Kankaanranta, "Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone, " European Journal of Pharmacology, vol. 406, no. 3, pp. 325-332, 2000.
    • (2000) European Journal of Pharmacology , vol.406 , Issue.3 , pp. 325-332
    • Zhang, X.1    Moilanen, E.2    Kankaanranta, H.3
  • 43
    • 0037119038 scopus 로고    scopus 로고
    • Divergent effect of mometasone on human eosinophil and neutrophil apoptosis
    • X. Zhang, E. Moilanen, I. M. Adcock, M. A. Lindsay, and H. Kankaanranta, "Divergent effect of mometasone on human eosinophil and neutrophil apoptosis, " Life Sciences, vol. 71, no. 13, pp. 1523-1534, 2002.
    • (2002) Life Sciences , vol.71 , Issue.13 , pp. 1523-1534
    • Zhang, X.1    Moilanen, E.2    Adcock, I.M.3    Lindsay, M.A.4    Kankaanranta, H.5
  • 44
    • 84860010929 scopus 로고    scopus 로고
    • Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor
    • N. A. Molfino, D. Gossage, R. Kolbeck, J. M. Parker, and G. P. Geba, "Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor, " Clinical & Experimental Allergy, vol. 42, no. 5, pp. 712-737, 2012.
    • (2012) Clinical & Experimental Allergy , vol.42 , Issue.5 , pp. 712-737
    • Molfino, N.A.1    Gossage, D.2    Kolbeck, R.3    Parker, J.M.4    Geba, G.P.5
  • 45
    • 84870821942 scopus 로고    scopus 로고
    • The potential of biologics for the treatment of asthma
    • G. Pelaia, A. Vatrella, and R. Maselli, "The potential of biologics for the treatment of asthma, " Nature Reviews Drug Discovery, vol. 11, no. 12, pp. 958-972, 2012.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.12 , pp. 958-972
    • Pelaia, G.1    Vatrella, A.2    Maselli, R.3
  • 47
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • P. Haldar, C. E. Brightling, B. Hargadon et al., "Mepolizumab and exacerbations of refractory eosinophilic asthma, " The New England Journal of Medicine, vol. 360, no. 10, pp. 973-984, 2009.
    • (2009) The New England Journal of Medicine , vol.360 , Issue.10 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3
  • 48
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
    • P. Nair, M.M.M. Pizzichini, M. Kjarsgaard et al., "Mepolizumab for prednisone-dependent asthma with sputum eosinophilia, " The New England Journal of Medicine, vol. 360, no. 10, pp. 985- 993, 2009.
    • (2009) The New England Journal of Medicine , vol.360 , Issue.10 , pp. 985-993
    • Nair, P.1    Pizzichini, M.M.M.2    Kjarsgaard, M.3
  • 49
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • I.D. Pavord, S. Korn, P. Howarth et al., "Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial, "The Lancet, vol. 380, no. 9842, pp. 651- 659, 2012.
    • (2012) The Lancet , vol.380 , Issue.9842 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3
  • 50
    • 84907424177 scopus 로고    scopus 로고
    • Mepolizumab treatment in patients with severe eosinophilic asthma
    • H. G. Ortega, M. C. Liu, I. D. Pavord et al., "Mepolizumab treatment in patients with severe eosinophilic asthma, " The New England Journal of Medicine, vol. 371, no. 13, pp. 1198-1207, 2014.
    • (2014) The New England Journal of Medicine , vol.371 , Issue.13 , pp. 1198-1207
    • Ortega, H.G.1    Liu, M.C.2    Pavord, I.D.3
  • 51
    • 81455155725 scopus 로고    scopus 로고
    • Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebocontrolled study
    • M. Castro, S. Mathur, F. Hargreave et al., "Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebocontrolled study, " American Journal of Respiratory and Critical Care Medicine, vol. 184, no. 10, pp. 1125-1132, 2011.
    • (2011) American Journal of Respiratory and Critical Care Medicine , vol.184 , Issue.10 , pp. 1125-1132
    • Castro, M.1    Mathur, S.2    Hargreave, F.3
  • 52
    • 77952683218 scopus 로고    scopus 로고
    • Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti- IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
    • W. W. Busse, R. Katial, D. Gossage et al., "Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti- IL-5 receptor α antibody, in a phase I study of subjects with mild asthma, " Journal of Allergy and Clinical Immunology, vol. 125, no. 6, pp. 1237-1244, 2010.
    • (2010) Journal of Allergy and Clinical Immunology , vol.125 , Issue.6 , pp. 1237-1244
    • Busse, W.W.1    Katial, R.2    Gossage, D.3
  • 53
    • 84919382915 scopus 로고    scopus 로고
    • Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: A phase 2b randomised dose-ranging study
    • M. Castro, S. E. Wenzel, E. R. Bleecker et al., "Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: A phase 2b randomised dose-ranging study, "The Lancet Respiratory Medicine, vol. 2, no. 11, pp. 879-890, 2014.
    • (2014) The Lancet Respiratory Medicine , vol.2 , Issue.11 , pp. 879-890
    • Castro, M.1    Wenzel, S.E.2    Bleecker, E.R.3
  • 54
    • 84889092877 scopus 로고    scopus 로고
    • Th17-mediated inflammation in asthma
    • D. C. Newcomb and R. S. Peebles, "Th17-mediated inflammation in asthma, " Current Opinion in Immunology, vol. 25, no. 6, pp. 755-760, 2013.
    • (2013) Current Opinion in Immunology , vol.25 , Issue.6 , pp. 755-760
    • Newcomb, D.C.1    Peebles, R.S.2
  • 55
    • 79959937269 scopus 로고    scopus 로고
    • Th17 cells: New players in asthma pathogenesis
    • L. Cosmi, F. Liotta, E. Maggi, S. Romagnani, and F. Annunziato, "Th17 cells: new players in asthma pathogenesis, " Allergy, vol. 66, no. 8, pp. 989-998, 2011.
    • (2011) Allergy , vol.66 , Issue.8 , pp. 989-998
    • Cosmi, L.1    Liotta, F.2    Maggi, E.3    Romagnani, S.4    Annunziato, F.5
  • 58
    • 84863475351 scopus 로고    scopus 로고
    • H17 cell differentiation by innate immune signals
    • H17 cell differentiation by innate immune signals, " Cellular &Molecular Immunology, vol. 9, no. 4, pp. 287-295, 2012.
    • (2012) Cellular &Molecular Immunology , vol.9 , Issue.4 , pp. 287-295
    • Huang, G.1    Wang, Y.2    Chi, H.3
  • 59
    • 33646577466 scopus 로고    scopus 로고
    • H17 and regulatory T cells
    • H17 and regulatory T cells, " Nature, vol. 441, no. 7090, pp. 235-238, 2006.
    • (2006) Nature , vol.441 , Issue.7090 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 60
    • 60749107176 scopus 로고    scopus 로고
    • The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
    • M. J. McGeachy, Y. Chen, C. M. Tato et al., "The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo, " Nature Immunology, vol. 10, no. 3, pp. 314-324, 2009.
    • (2009) Nature Immunology , vol.10 , Issue.3 , pp. 314-324
    • McGeachy, M.J.1    Chen, Y.2    Tato, C.M.3
  • 62
    • 84875257590 scopus 로고    scopus 로고
    • Smoking and asthma: Dangerous liaisons
    • R. Polosa and N. C.Thomson, "Smoking and asthma: dangerous liaisons, " European Respiratory Journal, vol. 41, no. 3, pp. 716- 725, 2013.
    • (2013) European Respiratory Journal , vol.41 , Issue.3 , pp. 716-725
    • Polosa, R.1    Thomson, N.C.2
  • 63
    • 84899817657 scopus 로고    scopus 로고
    • Inflammasomes in respiratory disease: From bench to bedside
    • G. G. Brusselle, S. Provoost, K. R. Bracke, A. Kuchmiy, and M. Lamkanfi, "Inflammasomes in respiratory disease: From bench to bedside, " Chest, vol. 145, no. 5, pp. 1121-1133, 2014.
    • (2014) Chest , vol.145 , Issue.5 , pp. 1121-1133
    • Brusselle, G.G.1    Provoost, S.2    Bracke, K.R.3    Kuchmiy, A.4    Lamkanfi, M.5
  • 64
    • 84964282095 scopus 로고    scopus 로고
    • Role of inflammasome activation in development and exacerbation of asthma
    • T.-H. Lee, H. J. Song, and C.-S. Park, "Role of inflammasome activation in development and exacerbation of asthma, " Asia Pacific Allergy, vol. 4, no. 4, pp. 187-196, 2014.
    • (2014) Asia Pacific Allergy , vol.4 , Issue.4 , pp. 187-196
    • Lee, T.-H.1    Song, H.J.2    Park, C.-S.3
  • 65
    • 33747074423 scopus 로고    scopus 로고
    • Serum amyloid A (SAA) in induced sputum of asthmatics: A new look to an old marker
    • F. Ozseker, S. Buyukozturk, B. Depboylu et al., "Serum amyloid A (SAA) in induced sputum of asthmatics: A new look to an old marker, " International Immunopharmacology, vol. 6, no. 10, pp. 1569-1576, 2006.
    • (2006) International Immunopharmacology , vol.6 , Issue.10 , pp. 1569-1576
    • Ozseker, F.1    Buyukozturk, S.2    Depboylu, B.3
  • 66
    • 84875169169 scopus 로고    scopus 로고
    • Alarmins, inflammasomes and immunity
    • N. Säid-Sadier and D. M. Ojcius, "Alarmins, inflammasomes and immunity, " Biomedical Journal, vol. 35, no. 6, pp. 437-449, 2012.
    • (2012) Biomedical Journal , vol.35 , Issue.6 , pp. 437-449
    • Säid-Sadier, N.1    Ojcius, D.M.2
  • 68
    • 84891889644 scopus 로고    scopus 로고
    • Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity
    • H.Y. Kim, H. J. Lee, Y.-J. Chang et al., "Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity, " Nature Medicine, vol. 20, no. 1, pp. 54-61, 2014.
    • (2014) Nature Medicine , vol.20 , Issue.1 , pp. 54-61
    • Kim, H.Y.1    Lee, H.J.2    Chang, Y.-J.3
  • 69
    • 84893064219 scopus 로고    scopus 로고
    • A tale of two cytokines: IL-17 and IL-22 in asthma and infection
    • M. L. Manni, K. M. Robinson, and J. F. Alcorn, "A tale of two cytokines: IL-17 and IL-22 in asthma and infection, " Expert Review of Respiratory Medicine, vol. 8, no. 1, pp. 25-42, 2014.
    • (2014) Expert Review of Respiratory Medicine , vol.8 , Issue.1 , pp. 25-42
    • Manni, M.L.1    Robinson, K.M.2    Alcorn, J.F.3
  • 70
    • 84893766480 scopus 로고    scopus 로고
    • Gata3 drives development of RORyt+ group 3 innate lymphoid cells
    • N. Serafini, R. G. Klein Wolterink, N. Satoh-Takayama et al., "Gata3 drives development of RORyt+ group 3 innate lymphoid cells, " Journal of Experimental Medicine, vol. 211, no. 2, pp. 199- 208, 2014.
    • (2014) Journal of Experimental Medicine , vol.211 , Issue.2 , pp. 199-208
    • Serafini, N.1    Wolterink, R.G.K.2    Satoh-Takayama, N.3
  • 71
    • 77952128925 scopus 로고    scopus 로고
    • Emerging roles of T helper subsets in the pathogenesis of asthma
    • D. M. Durrant and D. W. Metzger, "Emerging roles of T helper subsets in the pathogenesis of asthma, " Immunological Investigations, vol. 39, no. 4-5, pp. 526-549, 2010.
    • (2010) Immunological Investigations , vol.39 , Issue.4-5 , pp. 526-549
    • Durrant, D.M.1    Metzger, D.W.2
  • 72
    • 81055125976 scopus 로고    scopus 로고
    • The potential role of interleukin-17 in severe asthma
    • Y.-H. Wang and M. S. Wills-Karp, "The potential role of interleukin-17 in severe asthma, " Current Allergy and Asthma Reports, vol. 11, no. 5, pp. 388-394, 2011.
    • (2011) Current Allergy and Asthma Reports , vol.11 , Issue.5 , pp. 388-394
    • Wang, Y.-H.1    Wills-Karp, M.S.2
  • 73
    • 84874044175 scopus 로고    scopus 로고
    • T helper 17 cells in airway diseases from laboratory bench to bedside
    • R. Halwani, S. Al-Muhsen, and Q. Hamid, "T helper 17 cells in airway diseases from laboratory bench to bedside, " Chest, vol. 143, no. 2, pp. 494-501, 2013.
    • (2013) Chest , vol.143 , Issue.2 , pp. 494-501
    • Halwani, R.1    Al-Muhsen, S.2    Hamid, Q.3
  • 74
    • 84927096340 scopus 로고    scopus 로고
    • Interleukin-17 cytokine signalling in patients with asthma
    • A. Lindén and B. Dahlén, "Interleukin-17 cytokine signalling in patients with asthma, " European Respiratory Journal, vol. 44, no. 5, pp. 1319-1331, 2014.
    • (2014) European Respiratory Journal , vol.44 , Issue.5 , pp. 1319-1331
    • Lindén, A.1    Dahlén, B.2
  • 75
    • 79952744099 scopus 로고    scopus 로고
    • The molecular mechanisms of glucocorticoids-mediated neutrophil survival
    • A. S. Saffar, H. Ashdown, and A. S. Gounni, "The molecular mechanisms of glucocorticoids-mediated neutrophil survival, " Current Drug Targets, vol. 12, no. 4, pp. 556-562, 2011.
    • (2011) Current Drug Targets , vol.12 , Issue.4 , pp. 556-562
    • Saffar, A.S.1    Ashdown, H.2    Gounni, A.S.3
  • 76
    • 84890026323 scopus 로고    scopus 로고
    • Randomized, double blind, placebo-controlled study of brodalumab, a human anti- IL-17 receptor monoclonal antibody, in moderate to severe asthma
    • W.W. Busse, S. Holgate, E. Kerwin et al., "Randomized, doubleblind, placebo-controlled study of brodalumab, a human anti- IL-17 receptor monoclonal antibody, in moderate to severe asthma, "The American Journal of Respiratory and Critical Care Medicine, vol. 188, no. 11, pp. 1294-1302, 2013.
    • (2013) The American Journal of Respiratory and Critical Care Medicine , vol.188 , Issue.11 , pp. 1294-1302
    • Busse, W.W.1    Holgate, S.2    Kerwin, E.3
  • 77
    • 34548133569 scopus 로고    scopus 로고
    • Dendritic cells: A conductor of T cell differentiation
    • N. Kadowaki, "Dendritic cells: A conductor of T cell differentiation, " Allergology International, vol. 56, no. 3, pp. 193-199, 2007.
    • (2007) Allergology International , vol.56 , Issue.3 , pp. 193-199
    • Kadowaki, N.1
  • 78
    • 32644490529 scopus 로고    scopus 로고
    • Evidence of a role of tumor necrosis factor α in refractory asthma
    • M. A. Berry, B.Hargadon, M. Shelley et al., "Evidence of a role of tumor necrosis factor α in refractory asthma, " The New England Journal of Medicine, vol. 354, no. 7, pp. 697-708, 2006.
    • (2006) The New England Journal of Medicine , vol.354 , Issue.7 , pp. 697-708
    • Berry, M.A.1    Hargadon, B.2    Shelley, M.3
  • 79
    • 62549084077 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma
    • S. E. Wenzel, P. J. Barnes, E. R. Bleecker et al., "A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma, " American Journal of Respiratory and Critical Care Medicine, vol. 179, no. 7, pp. 549-558, 2009.
    • (2009) American Journal of Respiratory and Critical Care Medicine , vol.179 , Issue.7 , pp. 549-558
    • Wenzel, S.E.1    Barnes, P.J.2    Bleecker, E.R.3
  • 80
    • 61349156740 scopus 로고    scopus 로고
    • + T cells is associated with the phenotypes of allergic asthma
    • + T cells is associated with the phenotypes of allergic asthma, " Respirology, vol. 14, no. 2, pp. 187-194, 2009.
    • (2009) Respirology , vol.14 , Issue.2 , pp. 187-194
    • Matsumoto, K.1    Inoue, H.2    Fukuyama, S.3
  • 81
    • 70349200850 scopus 로고    scopus 로고
    • DecreasedFOXP3 protein expression in patients with asthma
    • S. Provoost, T. Maes, Y.M. vanDurme et al., "DecreasedFOXP3 protein expression in patients with asthma, " Allergy, vol. 64, no. 10, pp. 1539-1546, 2009.
    • (2009) Allergy , vol.64 , Issue.10 , pp. 1539-1546
    • Provoost, S.1    Maes, T.2    Van Durme, Y.M.3
  • 82
    • 84927178735 scopus 로고    scopus 로고
    • Regulatory T cells and immune regulation of allergic diseases: Roles of IL-10 and TGF-β
    • O. Palomares, M. Martín-Fontecha, R. Lauener et al., "Regulatory T cells and immune regulation of allergic diseases: roles of IL-10 and TGF-β, " Genes and Immunity, vol. 15, no. 8, pp. 511- 520, 2014.
    • (2014) Genes and Immunity , vol.15 , Issue.8 , pp. 511-520
    • Palomares, O.1    Martín-Fontecha, M.2    Lauener, R.3
  • 83
    • 78649516124 scopus 로고    scopus 로고
    • Functions of T cells in asthma: More than just Tα2 cells
    • C. M. Lloyd and E. M. Hessel, "Functions of T cells in asthma: more than just Tα2 cells, " Nature Reviews Immunology, vol. 10, no. 12, pp. 838-848, 2010.
    • (2010) Nature Reviews Immunology , vol.10 , Issue.12 , pp. 838-848
    • Lloyd, C.M.1    Hessel, E.M.2
  • 84
    • 58849162826 scopus 로고    scopus 로고
    • Acute exacerbations of asthma: Epidemiology, biology and the exacerbation-prone phenotype
    • R. H. Dougherty and J. V. Fahy, "Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype, " Clinical and Experimental Allergy, vol. 39, no. 2, pp. 193-202, 2009.
    • (2009) Clinical and Experimental Allergy , vol.39 , Issue.2 , pp. 193-202
    • Dougherty, R.H.1    Fahy, J.V.2
  • 85
    • 33748446393 scopus 로고    scopus 로고
    • Role of deficient type III interferon production in asthma exacerbations
    • M. Contoli, S. D. Message, V. Laza-Stanca et al., "Role of deficient type III interferon production in asthma exacerbations, " Nature Medicine, vol. 12, no. 9, pp. 1023-1026, 2006.
    • (2006) Nature Medicine , vol.12 , Issue.9 , pp. 1023-1026
    • Contoli, M.1    Message, S.D.2    Laza-Stanca, V.3
  • 86
    • 84870291769 scopus 로고    scopus 로고
    • Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma
    • S. Baraldo, M. Contoli, E. Bazzan et al., "Deficient antiviral immune responses in childhood: distinct roles of atopy and asthma, " Journal of Allergy and Clinical Immunology, vol. 130, no. 6, pp. 1307-1314, 2012.
    • (2012) Journal of Allergy and Clinical Immunology , vol.130 , Issue.6 , pp. 1307-1314
    • Baraldo, S.1    Contoli, M.2    Bazzan, E.3


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