Viral acute lower respiratory infections impair CD8 + T cells through PD-1

Journal of Clinical Investigation

Volumn 122, Issue 8, 2012, Pages 2967-2982

  Erickson, John J ^a   Gilchuk, Pavlo ^a   Hastings, Andrew K ^a   Tollefson, Sharon J ^a   Johnson, Monika ^a   Downing, Melissa B ^a   Boyd, Kelli L ^a   Johnson, Joyce E ^a   Kim, Annette S ^a   Joyce, Sebastian ^a   Williams, John V ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; PROGRAMMED DEATH 1 LIGAND 1; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; EPITOPE MAPPING; HUMAN; INFLUENZA A (H1N1); INFLUENZA VIRUS; LOWER RESPIRATORY TRACT INFECTION; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; METAPNEUMOVIRUS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARAINFLUENZA VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SIGNAL TRANSDUCTION; UPREGULATION; VIRAL RESPIRATORY TRACT INFECTION;

ACUTE DISEASE; ANIMALS; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; HLA-B7 ANTIGEN; HUMANS; IMIDAZOLES; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LUNG; METAPNEUMOVIRUS; MICE; MICE, TRANSGENIC; PARAMYXOVIRIDAE INFECTIONS; PROGRAMMED CELL DEATH 1 RECEPTOR; PYRIDINES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RESPIRATORY TRACT INFECTIONS; SIGNAL TRANSDUCTION; UP-REGULATION; VIRUS DISEASES;

EID: 84864755151     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI62860     Document Type: Article

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