Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG

European Journal of Immunology

Volumn 45, Issue 4, 2015, Pages 1170-1179

  Yildiz, Soner ^a   Alpdundar, Esin ^a   Gungor, Bilgi ^a   Kahraman, Tamer ^b   Bayyurt, Banu ^b   Gursel, Ihsan ^b   Gursel, Mayda ^a  

^a MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

^b BILKENT UNIVERSITY   (Turkey)

Author keywords

Arginine peptide (nona arginine); CGAMP; CpG ODN; Cyclic di GMP; Immunostimulation

Indexed keywords

ALPHA INTERFERON; ARGININE; BACTERIAL PROTEIN; BETA INTERFERON; CD11B ANTIGEN; CD14 ANTIGEN; CD45 ANTIGEN; CD86 ANTIGEN; CELL PENETRATING PEPTIDE; CPG OLIGODEOXYNUCLEOTIDE; CYCLIC DIGUANOSINE MONOPHOSPHATE; DINUCLEOTIDE; DNA; FLUORESCENT DYE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN P 15095; IMMUNOSTIMULATING AGENT; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 6; LIPOFECTAMINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN; TOLL LIKE RECEPTOR 9; TRYPAN BLUE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIS(3',5')-CYCLIC DIGUANYLIC ACID; CPG-OLIGONUCLEOTIDE; CYCLIC GMP; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE; CYTOKINE; IMMUNOLOGICAL ADJUVANT; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; OLIGODEOXYRIBONUCLEOTIDE; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CELL MATURATION; CELLULAR IMMUNITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG POTENTIATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INNATE IMMUNITY; INTERNALIZATION; LOW DRUG DOSE; MOUSE; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SPLEEN CELL; TUMOR VOLUME; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; CPG ISLAND; CYTOLOGY; DRUG EFFECTS; SPLEEN; TUMOR CELL CULTURE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL-PENETRATING PEPTIDES; CPG ISLANDS; CYCLIC GMP; CYTOKINES; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NUCLEOTIDES, CYCLIC; OLIGODEOXYRIBONUCLEOTIDES; PEPTIDES; SPLEEN; TUMOR CELLS, CULTURED;

EID: 84927027514     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445133     Document Type: Article

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