Combined CpG and poly I: C stimulation of monocytes results in unique signaling activation not observed with the individual ligands

Cellular Signalling

Volumn 25, Issue 11, 2013, Pages 2246-2254

  Arsenault, Ryan J ^a   Kogut, Michael H ^a   He, Haiqi ^a  

^a SOUTHERN PLAINS AGRICULTURAL RESEARCH CENTER   (United States)

Author keywords

CpG; Kinase; Peptide array; Poly I:C; Signaling; TLR synergy

Indexed keywords

ADIPOCYTOKINE; CALCIUM; CPG OLIGODEOXYNUCLEOTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PHOSPHOTRANSFERASE; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CELL CYCLE; CELL ISOLATION; CELL STIMULATION; CHICKEN; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ENZYME PHOSPHORYLATION; IMMUNE RESPONSE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACTIVATOR PROTEIN 1; AKT; AP-1; APOPTOSIS SIGNAL-REGULATING KINASE 1; ASK1; B CELL LINKER PROTEIN; BLNK; BRUTON TYROSINE KINASE; BTK; C/EBP; CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE 2; CALMODULIN; CAM; CAMK2; CAMP RESPONSE ELEMENT-BINDING PROTEIN; CCAAT/ENHANCER BINDING PROTEIN; CPG; CREB; DCS; DENDRITIC CELLS; ERK; EXTRACELLULAR SIGNAL-REGULATED KINASES; GENEONTOLOGY; GO; INDUCIBLE NITRIC OXIDE SYNTHASE; INOS; JAK-STAT; JANUS KINASE-SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION; JNK; JUN N-TERMINAL KINASE; KEGG; KINASE; KYOTO ENCYCLOPEDIA OF GENES AND GENOMES; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN-ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE 2; MK2; MKK3; MKK6; NFΚB; NITRIC OXIDE; NO; NUCLEAR FACTOR ΚB; PAMPS; PATHOGEN-ASSOCIATED MOLECULAR PATTERNS; PATTERN RECOGNITION RECEPTORS; PBMCS; PEPTIDE ARRAY; PERIPHERAL BLOOD MONONUCLEAR CELLS; PHOSPHOINOSITIDE 3-KINASE; PHOSPHOLIPASE C GAMMA; PI3K; PKB; PKC; PLCΓ; POLY I:C; POLYINOSINIC-POLYCYTIDYLIC ACID; PROTEIN KINASE B; PROTEIN KINASE C; PRRS; RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE 1/2; RAC1; RAF; RAPIDLY ACCELERATED FIBROSARCOMA; RAS; RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1; RAT SARCOMA; RIBOSOMAL S6 KINASE 1; RSK1 ALSO REFERRED TO AS P90RSK; SEARCH TOOL FOR THE RETRIEVAL OF INTERACTING GENES; SIGNALING; STRING; TAK1; TANK-BINDING KINASE 1; TBK1; TGF-BETA ACTIVATED KINASE 1; TLR SYNERGY; TLRS; TOLL-LIKE RECEPTORS; UNMETHYLATED CPG OLIGODEOXYNUCLEOTIDES;

ANIMALS; ANIMALS, NEWBORN; CHICKENS; CPG ISLANDS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DRUG SYNERGISM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMOBILIZED PROTEINS; MONOCYTES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHORYLATION; POLY I-C; PRIMARY CELL CULTURE; PROTEIN ARRAY ANALYSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84882764845     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.07.014     Document Type: Article

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