Central adiposity and the functional magnetic resonance imaging response to cognitive challenge

International Journal of Obesity

Volumn 38, Issue 9, 2014, Pages 1193-1199

  Gonzales, M M ^a   Kaur, S ^a   Eagan, D E ^a   Goudarzi, K ^a   Pasha, E ^a   Doan, D C ^a   Tanaka, H ^a   Haley, A P ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

2 back task; fMRI; waist circumference; working memory

Indexed keywords

CHOLESTEROL; OXYGEN;

ADULT; AGE; ARTICLE; BOLD SIGNAL; BOOTSTRAPPING; CENTRAL NERVOUS SYSTEM; CHOLESTEROL BLOOD LEVEL; COGNITION; CONFIDENCE INTERVAL; CORRELATION ANALYSIS; EDUCATION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; HUMAN EXPERIMENT; MALE; MIDDLE FRONTAL GYRUS; OBESITY; PRIORITY JOURNAL; REGRESSION ANALYSIS; RESPONSE TIME; SEX; SUPERIOR FRONTAL GYRUS; SYSTOLIC BLOOD PRESSURE; TASK PERFORMANCE; VERBAL MEMORY; WAIST CIRCUMFERENCE; WORKING MEMORY; ABDOMINAL OBESITY; BLOOD; FRONTAL LOBE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PSYCHOLOGY; SHORT TERM MEMORY; VASCULARIZATION;

ADULT; COGNITION; FEMALE; FRONTAL LOBE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY, SHORT-TERM; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TESTS; OBESITY, ABDOMINAL; OXYGEN; TASK PERFORMANCE AND ANALYSIS; WAIST CIRCUMFERENCE;

EID: 84926991779     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2014.5     Document Type: Article

References (60)

1. World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organization: Geneva, Switzerland, 2000.
2. Kopelman PG. Obesity as a medical problem. Nature 2000; 404: 635-643.
3. Gustafson D, Lissner L, Bengtsson C, Bjorkelund C, Skoog I. A 24-year follow-up of body mass index and cerebral atrophy. Neurology 2004; 63: 1876-1881.
4. Walther K, Birdsill AC, Glisky EL, Ryan L. Structural brain differences and cognitive functioning related to body mass index in older females. Hum Brain Mapp 2009; 31: 1052-1064.
5. Ward M, Carlsson C, Trivedi M, Sager M, Johnson S. The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study. BMC Neurol 2005; 5: 23.
6. Whitmer RA, Gustafson DR, Barrett-Connor E, Haan MN, Gunderson EP, Yaffe K. Central obesity and increased risk of dementia more than three decades later. Neurology 2008; 71: 1057-1064.
7. Gustafson D, Rothenberg E, Blennow K, Steen B, Skoog I. An 18-year follow-up of overweight and risk of Alzheimer disease. Arch Inter Med 2003; 163: 1524-1528.
8. Gustafson DR. Adiposity hormones and dementia. J Neurol Sci 2010; 299: 30-34.
9. Cereda E, Sansone V, Meola G, Malavazos AE. Increased visceral adipose tissue rather than BMI as a risk factor for dementia. Age Ageing 2007; 36: 488-491.
10. Ibrahim MM. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Rev 2010; 11: 11-18.
11. Wisse BE. The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J Am Soc Nephrol 2004; 15: 2792-2800.
12. Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr Alzheimer Res 2007; 4: 111-116.
13. Gustafson D. A life course of adiposity and dementia. Eur J Pharmacol 2008; 585: 163-175.
14. Bondi MW, Houston WS, Eyler LT, Brown GG. fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease. Neurology 2005; 64: 501-508.
15. Braskie MN, Small GW, Bookheimer SY. Vascular health risks and fMRI activation during a memory task in older adults. Neurobiol Aging 2010; 31: 1532-1542.
16. Gonzales M, Tarumi T, Miles S, Tanaka H, Shah F, Haley A. Insulin Sensitivity as a mediator of the relationship between body mass index and working memoryrelated brain activation. Obesity 2010; 18: 2131-2137.
17. Volkow ND, Wang GJ, Telang F, Fowler JS, Goldstein RZ, Alia-Klein N et al. Inverse association between BMI and prefrontal metabolic activity in healthy adults. Obesity 2008; 17: 60-65.
18. Haley AP, Sweet LH, Gunstad J, Forman DE, Poppas A, Paul RH et al. Verbal working memory and atherosclerosis in patients with cardiovascular disease: an fMRI study. J Neuroimaging 2007; 17: 227-233.
19. Owen AM, McMillan KM, Laird AR, Bullmore E. N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies. Hum Brain Mapp 2005; 25: 46-59.
20. Braver TS, Cohen JD, Nystrom LE, Jonides J, Smith EE, Noll DC. A parametric study of prefrontal cortex involvement in human working memory. Neuroimage 1997; 5: 49-62.
21. Pouliot M-C, Després J-P, Lemieux S, Moorjani S, Bouchard C, Tremblay A et al. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol 1994; 73: 460-468.
22. World Health Organization. Waist Circumference and Waist-Hip Ratio: Report of a WHO Expert Consulation. World Health Organization: Geneva, Switzerland, 2008.
23. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
24. Wechsler D. WASI II: Wechsler Abbreviated Scale of Intelligence. 2nd edn. Psychological Corporation: San Antonio, TX, USA, 2011.
25. Delis DC, Kramer JH, Kaplan E, Ober BA. California Verbal Learning Test. 2nd edn. The Psychological Corporation: San Antonio, TX, USA, 2000.
26. Reitan RM. Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958; 8: 271-276.
27. Ruff RM, Light RH, Parker SB, Levin HS. Benton Controlled Oral Word Association Test: reliability and updated norms. Arch Clin Neuropsychol 1996; 11: 329-338.
28. Wechsler D. Wechsler Adult Intelligence Scale. 4th edn. Psychological Corporation: San Antonio, TX, USA, 2008.
29. Golden CJ. Stroop Color and Word Test: A Manual for Clinical and Experimental Uses. Skoelting: Chicago, IL, USA, 1978.
30. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17: 825-841.
31. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp 2002; 17: 143-155.
32. Jaeggi SM, Buschkuehl M, Perrig WJ, Meier B. The concurrent validity of the N-back task as a working memory measure. Memory 2010; 18: 394-412.
33. Laird AR, Robinson JL, McMillan KM, Tordesillas-Gutiérrez D, Moran ST, Gonzales SM et al. Comparison of the disparity between Talairach and MNI coordinates in functional neuroimaging data: Validation of the Lancaster transform. Neuroimage 2010; 51: 677-683.
34. Galioto RM, Alosco ML, Spitznagel MB, Stanek KM, Gunstad J. Cognitive reserve preserves cognitive function in obese individuals. Aging Neuropsychol C 2013; 20: 684-699.
35. Baddeley A. Working memory. Science 1992; 255: 556-559.
36. Cabeza R, Anderson ND, Locantore JK, McIntosh AR. Aging gracefully: compensatory brain activity in high-performing older adults. Neuroimage 2002; 17: 1394-1402.
37. Rypma B, D'Esposito M. Isolating the neural mechanisms of age-related changes in human working memory. Nat Neurosci 2000; 3: 509-515.
38. Malavazos AE, Corsi MM, Ermetici F, Coman C, Sardanelli F, Rossi A et al. Proinflammatory cytokines and cardiac abnormalities in uncomplicated obesity: relationship with abdominal fat deposition. Nutr Metab Cardiovasc Dis 2007; 17: 294-302.
39. Banks WA, Kastin AJ, Broadwell RD. Passage of cytokines across the blood-brain barrier. Neuroimmunomodulation 1995; 2: 241-248.
40. Koutsilieri E, Scheller C, Tribl F, Riederer P. Degeneration of neuronal cells due to oxidative stress-microglial contribution. Parkinsonism Relat Disord 2002; 8: 401-406.
41. Weaver JD, Huang M-H, Albert M, Harris T, Rowe JW, Seeman TE. Interleukin-6 and risk of cognitive decline MacArthur Studies of Successful Aging. Neurology 2002; 59: 371-378.
42. Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS et al. Inflammatory biomarkers are associated with total brain volume The Framingham Heart Study. Neurology 2007; 68: 1032-1038.
43. Satizabal CL, Zhu YC, Mazoyer B, Dufouil C, Tzourio C. Circulating IL-6 and CRP are associated with MRI findings in the elderly The 3C-Dijon Study. Neurology 2012; 78: 720-727.
44. Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB et al. Inflammatory markers and the risk of Alzheimer disease The Framingham Study. Neurology 2007; 68: 1902-1908.
45. Hull M, Strauss S, Berger M, Volk B, Bauer J. The participation of interleukin-6, a stress-inducible cytokine, in the pathogenesis of Alzheimer's disease. Behav Brain Res 1996; 78: 37-41.
46. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995; 1: 1155-1161.
47. Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996; 17: 305-311.
48. Oomura Y, Aou S, Fukunaga K. Prandial increase of leptin in the brain activates spatial learning and memory. Pathophysiology 2010; 17: 119-127.
49. Banerji MA, Buckley MC, Chaiken RL, Gordon D, Lebovitz HE, Kral JG. Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulinresistant black men with NIDDM. Int J Obes Relat Metab Disord 1995; 19: 846-850.
50. Banks WA, Coon AB, Robinson SM, Moinuddin A, Shultz JM, Nakaoke R et al. Triglycerides induce leptin resistance at the blood-brain barrier. Diabetes 2004; 53: 1253-1260.
51. Holden KF, Lindquist K, Tylavsky FA, Rosano C, Harris TB, Yaffe K. Serum leptin level and cognition in the elderly: Findings from the Health ABC Study. Neurobiol Aging 2009; 30: 1483-1489.
52. Pannacciulli N, Le DSN, Chen K, Reiman EM, Krakoff J. Relationships between plasma leptin concentrations and human brain structure: a voxel-based morphometric study. Neurosci Lett 2007; 412: 248-253.
53. Huang X-F, Zavitsanou K, Huang X, Yu Y, Wang H, Chen F et al. Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity. Behav Brain Res 2006; 175: 415-419.
54. Wang GJ, Volkow ND, Logan J, Pappas NR, Wong CT, Zhu W et al. Brain dopamine and obesity. Lancet 2001; 357: 354-357.
55. Brunetti L, Orlando G, Recinella L, Michelotto B, Ferrante C, Vacca M. Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus. Eur J Pharmacol 2004; 493: 41-44.
56. Brunetti L, Michelotto B, Orlando G, Vacca M. Leptin inhibits norepinephrine and dopamine release from rat hypothalamic neuronal endings. Eur J Pharmacol 1999; 372: 237-240.
57. Vernaleken I, Buchholz H-G, Kumakura Y, Siessmeier T, Stoeter P, Bartenstein P et al. 'Prefrontal' cognitive performance of healthy subjects positively correlates with cerebral FDOPA influx: An exploratory [18F]-fluoro-L-DOPA-PET investigation. Hum Brain Mapp 2007; 28: 931-939.
58. Mozley LH, Gur RC, Mozley PD, Gur RE. Striatal dopamine transporters and cognitive functioning in healthy men and women. Am J Psychiatry 2001; 158: 1492-1499.
59. Seamans JK, Yang CR. The principal features and mechanisms of dopamine modulation in the prefrontal cortex. Prog Neurobiol 2004; 74: 1-58.
60. Bäckman L, Karlsson S, Fischer H, Karlsson P, Brehmer Y, Rieckmann A et al. Dopamine D(1) receptors and age differences in brain activation during working memory. Neurobiol Aging 2011; 32: 1849-1856.