Guanine nucleotide exchange factor αPIX leads to activation of the Rac 1 GTPase/glycogen phosphorylase pathway in interleukin (IL)-2-stimulated T cells

Journal of Biological Chemistry

Volumn 290, Issue 14, 2015, Pages 9171-9182

  Llavero, Francisco ^a,b   Urzelai, Bakarne ^a   Osinalde, Nerea ^c   Gálvez, Patricia ^d   Lacerda, Hadriano M ^e   Parada, Luis A ^f   Zugaza, José L ^a,b,g  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b ACHUCARRO BASQUE CENTER FOR NEUROSCIENCE   (Spain)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d Pharmascience Division Technological Park of Health Sciences   (Spain)

^e UNIVERSITY OF TURIN   (Italy)

^f UNIVERSIDAD NACIONAL DE SALTA   (Argentina)

^g BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL PROLIFERATION; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; ENZYME ACTIVITY; MOBILE SECURITY; NUCLEOTIDES; PHOSPHORYLATION; POSITIVE IONS; T-CELLS;

BIOLOGICAL SIGNIFICANCE; DIRECTED MUTAGENESIS; ENZYMATIC ACTIVITIES; GLYCOGEN PHOSPHORYLASE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; RECEPTOR ACTIVATION; SERINE PHOSPHORYLATION; T-CELL ANTIGEN RECEPTORS;

CELL SIGNALING;

ALPHA PIX PROTEIN; GLYCOGEN PHOSPHORYLASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 2; PROTEIN KINASE C THETA; PROTEIN SERINE THREONINE KINASE; RAC1 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; ARHGEF6 PROTEIN, HUMAN; INTERLEUKIN 12; PRIMER DNA; RAC1 PROTEIN, HUMAN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; T LYMPHOCYTE; CELL LINE; CELL PROLIFERATION; DRUG EFFECTS; ENZYMOLOGY; HUMAN; METABOLISM; NEUTROPHIL CHEMOTAXIS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

BASE SEQUENCE; CELL LINE; CELL PROLIFERATION; CHEMOTAXIS, LEUKOCYTE; DNA PRIMERS; ENZYME ACTIVATION; GLYCOGEN PHOSPHORYLASE; HUMANS; INTERLEUKIN-12; POLYMERASE CHAIN REACTION; RAC1 GTP-BINDING PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; T-LYMPHOCYTES;

EID: 84926687801     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.608414     Document Type: Article

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