Role of Tiam1 in rac-mediated signal transduction pathways

Current Topics in Microbiology and Immunology

Volumn 213 II, Issue , 1996, Pages 253-265

  Collard, J G ^a   Habets, G G M ^a   Michiels, F ^a   Stam, J ^a   Van Der Kammen, R A ^a   Van Leeuwen, F ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

RHO FACTOR;

CHROMOSOMAL LOCALIZATION; GENE EXPRESSION; HUMAN; METASTASIS; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; SIGNAL TRANSDUCTION;

EID: 0029892624     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-61109-4_12     Document Type: Review

References (73)

1. Arcaro A, Wymann MP (1993) Worthmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses Biochem J 296: 297-301
2. Avraham H, Weinberg RA (1989) Characterization and expression of the human rho 12 gene product Mol Cell Biol 9. 2058-2066
3. Behrens J, Mareel MM, Van Roy FM, Birchmeier W (1990) Dissecting tumor cell invasion: epithelial cells acquire invasive properties after loss of Uvomorulin-mediated cell-cell adhesion. J Cell Biol 108 2435-2447
4. Bevilacqua G, Sobel ME, Liotta LA, Steeg PS (1989) Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential Cancer Res 49: 5185-5190
5. Boguski MS, McCormick F (1993) Proteins regulating Ras and its relatives Nature 366. 643-654
6. Bourne HR, Sanders DA, McCormick F (1990) The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348: 125-132
7. Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349: 117-127
8. Buday L, Downward J (1993) Epidermal growth factor regulates p21(ras) through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell 73: 611-620
9. Chan BMC, Matsuura N, Takada Y, Zetter BR, Hemler ME (1991) In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells. Science 251. 1600-1602
10. Chardin P, Boquet P, Madaule P, Popoff MR, Rubin EJ, Gill DM (1989) The mammalian G protein rho C is ADP-ribosylated by clostridium botulinum exoenzyme C3 and affects actin microfilaments in vero cells. EMBO J 8: 1087-1092
11. Chong LD, Traynorkaplan A, Bokoch GM, Schwartz MA (1994) The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79. 507-513
12. Collard JG, Schijven JF, Roos E (1987a) Invasive and metastatic potential induced by ras-transfection into mouse BW5147 T lymphoma cells Cancer Res 47: 754-759
13. Collard JG, Van de Poll M, Scheffer A, Roos E, Hopman AHM, Geurts van Kessel AHM, Van Dongen JJM (1987b) Location of genes involved in invasion and metastasis on human chromosome 7. Cancer Res 47: 6666-6670
14. Collard JG, Roos E, La Rivière G, Habets GGM (1988) Genetic analysis of invasion and metastasis. Cancer Surv 7: 692-710
15. Collard JG, Habets GGM, Van der Kammen R, Scholtes E (1989) Genetic basis of T lymphoma invasion. Invasion Metastasis 9: 379-390
16. Cook S, McCormick F (1994) Signal transduction-Ras blooms on sterile ground. Nature 369: 361-362
17. Downward J (1992) Signal transduction. Rac and Rho in tune. Nature 359: 273-274
18. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363: 45-51
19. Eva A, Vecchio G, Rao CD, Tronick SR, Aaronson SA (1988) The predicted DBL oncogene product defines a distinct class of transforming proteins Proc Natl Acad Sci USA 85: 2061-2065
20. Fry MJ, Waterfield MD (1993) Structure and function of phosphatidylinositol 3-kinase, a potential second messenger system involved in growth control. Philos Trans R Soc Lond Biol 340: 337-344
21. Fukami K, Furuhashi K, Inagaki M, Endo T, Hatano S, Takenawa T (1992) Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function Nature 359: 150-152
22. Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Barsagi D (1993) Grb2 Mediates the EGF-dependent activation of guanine nucleotide Exchange on Ras Nature 363: 88-92
23. Gibson TJ, Hyvonen M, Birney E, Musacchio A, Saraste M (1994) PH domain - the first anniversary Trends Biochem Sci 19: 349-353
24. Günthert U, Hofmann M, Rudy W, Reber S, Zöller M, Haussman I, Matzku S, Wenzel A, Ponta H, Herrlich P (1991) A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 65: 13-24
25. Habets GGM, Van der Kammen R, Scholtes WHM, Collard JG (1990) Induction of invasive and metastatic potential in mouse T lymphoma cells (BW5147) by treatment with 5-azacytidine. Clin Exp Metastasis 8. 567-577
26. Habets GGM, Van der Kammen RA, Willemsen V, Balemans M, Wiegant J, Collard JG (1992) Sublocalization of an invasion-inducing locus and other genes on human chromosome 7 Cytogenet Cell Genet 60: 200-205
27. Habets GGM, Scholtes EHM, Zuydgeest D, Van der Kammen RA, Stam JC, Berns A, Collard JG (1994) Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for rho-like proteins Cell 77: 537-549
28. Habets GGM, Van der Kammen RA, Jenkins NA, Gilbert DJ, Copeland NG, Hagemeijer A, Collard JG (1995a) The invasion-inducing TIAM-1 gene maps to human chromosome band 21q22 and mouse chromosome 16. Cytogenet Cell Genet 70 48-51
29. Habets GGM, van der Kammen RA, Stam JC, Michiels F, Collard JG (1995b) Sequence of the human invasion-inducing TIAM1 gene, its conversion in evolution and its expression in tumor cell lines of different tissue origin Oncogene 10 1371-1376
30. Hall A (1990) The cellular functions of small GTP-binding proteins. Science 249: 635-640
31. Hall A (1992) Ras-related GTPases and the cytoskeleton. Mol Biol Cell 3: 475-479
32. Harlan JE, Hajduk PJ, Yoon HS, Fesik SW (1994) Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate Nature 371: 168-170
33. Hart MJ, Eva A, Zangrilli D, Aaronson SA, Evans T, Cerione RA, Zheng Y (1994) Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J Biol Chem 269: 62-65
34. Horii Y, Beeler JF, Sakaguchi K, Tachibana M, Miki T (1994) A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentiality links Rho and Rac signaling pathways. EMBO J 13: 4776-4786
35. Imamura F, Horai T, Mukai M, Shinkai K, Sawada M, Akedo H (1993) Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D. Biochem Biophys Res Commun 193: 497-503
36. Katzav S, Martin-Zanca D, Barbacid M (1989) Vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. EMBO J 8: 2283-2290
37. Katzav S, Cleveland JL, Heslop HE, Pulido D (1991) Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential. Mol Cell Biol 11: 1912-1920
38. Lassing I, Lindberg U (1985) Specific interaction between phosphatidylinositol 4,5 bisphosphate and profilactin. Nature 314: 472-474
39. Leevers SJ, Paterson HF, Marshall CJ (1994) Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane Nature 369: 411-420
40. Leone A, Flatow U, King CR, Sandeen MA, Margulies IM, Liotta LA, Steeg PS (1991) Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell 65. 25-35
41. Liotta LA, Steeg P, Stetler Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation Cell 64: 327-336
42. Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L (1994) A brain serine threonine protein kinase activated by Cdc42 and Rac1. Nature 367: 40-46
43. McGlade J, Brunkhorst B, Anderson D, Mbamalu G, Settleman J, Dedhar S, Rozakis-Adcock M, Chen LB, Pawson T (1993) The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J 12. 3073-3081
44. Michiels F, Habets GGM, Stam JC, Van der Kammen RA, Collard JG (1995) A role for Rac in Tiam1-induced membrane ruffling and invasion Nature 375: 338-340
45. Miki T, Smith CL, Long JE, Eva A, Fleming TP (1993) Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature 362: 462-465 (erratum published in Nature 364: 737)
46. Nobes C, Hawkins P, Stephens L, Hall A (1995) Activation of the small GTP-binding proteins Rho and Rac by growth factor receptors. J Cell Sci 108: 225-233
47. Parker PJ, Waterfield MD (1992) Phosphatidylinositol 3-kinase: a novel effector. Cell Growth Differ 3: 747-752
48. Paterson HF, Self AJ, Garrett MD, Just I, Aktories K, Hall A (1990) Microinjection of recombinant p21rho induces rapid changes in cell morphology. J Cell Biol 111. 1001-1007
49. Perona R, Esteve P, Jimenez B, Ballestero RP, Cajal SR (1993) Tumorigenic activity of rho genes from aplysia-californica Oncogene 8: 1285-1292
50. Ponting CP, Philips C (1995) DHR domains in synthrophins, neuronal NO synthases and other intracellular proteins. Trends Biochem Sci 20. 102-103
51. Qiu R, Kim D, McCormick F, Symons M (1995) An essential role for Rac in Ras transformation. Nature 374: 457-459
52. Reinhard J, Scheel AA, Diekmann D, Hall A, Ruppert C, Bahler M (1995) A novel type of myosin implicated in signalling by Rho family GTPases. EMBO J 14. 101-108
53. Ridley AJ (1994) Membrane ruffling and signal transduction. Bioessays 16: 321-327
54. Ridley AJ, Hall A (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibres in response to growth factors. Cell 70: 389-399
55. Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70. 401-410
56. Ridley A, Self AJ, Kasmi F, Paterson HF, Hall A, Marshall CJ, Ellis C (1993) Rho family GTPase activating proteins p190, Bcr and RhoGAP show distinct specificities in vitro and in vivo. EMBO J 12: 5151-5160
57. Roos E, La Rivière G, Collard JG, Stukart MJ, de Baetselier P (1985) Invasiveness of T cell hybridomas in vitro and their metastatic potential in vivo Cancer Res 45 6238-6243
58. Roossien FF, de Rijk D, Bikker A, Roos E (1989) Involvement of LFA-1 in lymphoma invasion and metastasis demonstrated with LFA-1-deficient mutants. J Cell Biol 108: 1979-1985
59. Sekine A, Fujiwara M, Narumiya S (1989) Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J Biol Chem 264: 8602-8605
60. Settleman J, Albright CF, Foster LC, Weinberg RA (1992a) Association between GTPase activators for Rho and Ras families. Nature 359. 153-154
61. Settleman J, Narashimhan V, Foster LC, Weinberg RA (1992b) Molecular cloning of cdnas encoding the gap-associated protein p190: implications for a signaling pathway from ras to the nucleus. Cell 69: 539-549
62. Simon MA, Dodson GS, Rubin GM (1993) An SH3-SH2-SH3 protein is required for p21 (Ras 1) activation and binds to sevenless and Sos proteins in vitro Cell 73: 169-177
63. Takaishi K, Kikuchi A, Kuroda S, Kotani K, Sasaki T, Takai Y (1993) Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol Cell Biol 13. 72-79
64. Takaishi K, Sasaski T, Kato M, Yamochi W, Kuroda S, Nakamura T, Takeichi M, Takai Y (1994) involvement of Rho P21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene 9: 273-279
65. Tominaga T, Sugie K, Hirata M, Morii N, Fukata J, Uchida A, Narumiya S (1993) Inhibition of PMA-induced, Ifa-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho J Cell Biol 120: 1529-1537
66. van Corven EJ, Groenink A, Jalink K, Eichholtz T, Moolenaar WH (1989) Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 59: 45-54
67. van der Bend RL, Brunner J, Jalink K, van Corven EJ, Moolenaar WH, van Blitters WJ (1992) Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J 11. 2495-2501
68. van Leeuwen FN, van der Kammen RA, Habets GGM, Collard JG (1995) Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells Oncogene 11: 2215-2221
69. Vleminckx K, Vakaet L Jr, Mareel M, Fiers W, Van Roy F (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66: 107-119
70. Wennstrom S, Hawkins P, Cooke F, Hara K, Yonezawa K, Kasuga M, Jackson T, Claesson-Welsh L, Stephens L (1994) Activation of phosphomositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol 4: 385-393
71. Weilenga VJM, Heider KH, Offerhaus GJA, Adolf GR, Van Den berg FM, Ponta H, Herrlich P, Pals ST (1993) Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res 53. 4754-4756
72. Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y (1993) Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268: 25846-25856
73. Zheng Y, Cerione R, Bender A (1994) Control of the yeast bud-site assembly GTPase Cdc42 - catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J Biol Chem 269. 2369-2372