-
1
-
-
0027109075
-
Cancer p53, guardian of the genome
-
Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358: 15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
2
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88: 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
3
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia AJ, Kastan MB. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 1998; 12: 2973-2983.
-
(1998)
Genes Dev
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
4
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev 1996; 10: 1054-1072.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
7
-
-
33845972685
-
P53 and tumor suppression
-
Van Dyke T. p53 and tumor suppression. N Engl J Med 2007; 356: 79-81.
-
(2007)
N Engl J Med
, vol.356
, pp. 79-81
-
-
Van Dyke, T.1
-
8
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992; 69: 1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
9
-
-
77449101168
-
Mdm2-mediated ubiquitylation: P53 and beyond
-
Marine JC, Lozano G. Mdm2-mediated ubiquitylation: p53 and beyond. Cell Death Differ 2010; 17: 93-102.
-
Cell Death Differ
, vol.2010
, Issue.17
, pp. 93-102
-
-
Marine, J.C.1
Lozano, G.2
-
10
-
-
0034282102
-
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
-
Boyd SD, Tsai KY, Jacks T. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. Nat Cell Biol 2000; 2: 563-568.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 563-568
-
-
Boyd, S.D.1
Tsai, K.Y.2
Jacks, T.3
-
11
-
-
0034282220
-
The MDM2 RING-finger domain is required to promote p53 nuclear export
-
Geyer RK, Yu ZK, Maki CG. The MDM2 RING-finger domain is required to promote p53 nuclear export. Nat Cell Biol 2000; 2: 569-573.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 569-573
-
-
Geyer, R.K.1
Yu, Z.K.2
Maki, C.G.3
-
12
-
-
0033559256
-
A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J 1999; 18: 1660-1672.
-
(1999)
EMBO J
, vol.18
, pp. 1660-1672
-
-
Stommel, J.M.1
Marchenko, N.D.2
Jimenez, G.S.3
Moll, U.M.4
Hope, T.J.5
Wahl, G.M.6
-
13
-
-
26844433194
-
Antiinflammatory action of glucocorticoids-new mechanisms for old drugs
-
Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 2005; 353: 1711-1723.
-
(2005)
N Engl J Med
, vol.353
, pp. 1711-1723
-
-
Rhen, T.1
Cidlowski, J.A.2
-
14
-
-
84883769810
-
Glucocorticoid receptor signaling in health and disease
-
Kadmiel M, Cidlowski JA. Glucocorticoid receptor signaling in health and disease. Trends Pharmacol Sci 2013; 34: 518-530.
-
Trends Pharmacol Sci
, vol.2013
, Issue.34
, pp. 518-530
-
-
Kadmiel, M.1
Cidlowski, J.A.2
-
15
-
-
0031415218
-
A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death
-
D'Adamio F, Zollo O, Moraca R, Ayroldi E, Bruscoli S, Bartoli A et al. A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death. Immunity 1997; 7: 803-812.
-
(1997)
Immunity
, vol.7
, pp. 803-812
-
-
D'adamio, F.1
Zollo, O.2
Moraca, R.3
Ayroldi, E.4
Bruscoli, S.5
Bartoli, A.6
-
16
-
-
0035095320
-
Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene
-
Cannarile L, Zollo O, D'Adamio F, Ayroldi E, Marchetti C, Tabilio A et al. Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene. Cell Death Differ 2001; 8: 201-203.
-
(2001)
Cell Death Differ
, vol.8
, pp. 201-203
-
-
Cannarile, L.1
Zollo, O.2
D'adamio, F.3
Ayroldi, E.4
Marchetti, C.5
Tabilio, A.6
-
17
-
-
77951237725
-
Glucocorticoidinduced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids
-
Bruscoli S, Donato V, Velardi E, Di Sante M, Migliorati G, Donato R et al. Glucocorticoidinduced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids. J Biol Chem 2010; 285: 10385-10396.
-
J Biol Chem
, vol.2010
, Issue.285
, pp. 10385-10396
-
-
Bruscoli, S.1
Donato, V.2
Velardi, E.3
Di Sante, M.4
Migliorati, G.5
Donato, R.6
-
18
-
-
70350534804
-
Glucocorticoid-induced leucine zipper (GILZ): A new important mediator of glucocorticoid action
-
Ayroldi E, Riccardi C. Glucocorticoid-induced leucine zipper (GILZ): a new important mediator of glucocorticoid action. FASEB J 2009; 23: 3649-3658.
-
(2009)
FASEB J
, vol.23
, pp. 3649-3658
-
-
Ayroldi, E.1
Riccardi, C.2
-
19
-
-
79958118789
-
Role of GILZ in immune regulation, glucocorticoid actions and rheumatoid arthritis
-
Beaulieu E, Morand EF. Role of GILZ in immune regulation, glucocorticoid actions and rheumatoid arthritis. Nat Rev Rheumatol 2011; 7: 340-348.
-
Nat Rev Rheumatol
, vol.2011
, Issue.7
, pp. 340-348
-
-
Beaulieu, E.1
Morand, E.F.2
-
20
-
-
0035437169
-
Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB
-
Ayroldi E, Migliorati G, Bruscoli S, Marchetti C, Zollo O, Cannarile L et al. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. Blood 2001; 98: 743-753.
-
(2001)
Blood
, vol.98
, pp. 743-753
-
-
Ayroldi, E.1
Migliorati, G.2
Bruscoli, S.3
Marchetti, C.4
Zollo, O.5
Cannarile, L.6
-
21
-
-
31544454399
-
Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines
-
Cannarile L, Fallarino F, Agostini M, Cuzzocrea S, Mazzon E, Vacca C et al. Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines. Blood 2006; 107: 1039-1047.
-
(2006)
Blood
, vol.107
, pp. 1039-1047
-
-
Cannarile, L.1
Fallarino, F.2
Agostini, M.3
Cuzzocrea, S.4
Mazzon, E.5
Vacca, C.6
-
22
-
-
58649114086
-
Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis
-
Cannarile L, Cuzzocrea S, Santucci L, Agostini M, Mazzon E, Esposito E et al. Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. Gastroenterology 2009; 136: 530-541.
-
(2009)
Gastroenterology
, vol.136
, pp. 530-541
-
-
Cannarile, L.1
Cuzzocrea, S.2
Santucci, L.3
Agostini, M.4
Mazzon, E.5
Esposito, E.6
-
23
-
-
84874699620
-
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome
-
Pinheiro I, Dejager L, Petta I, Vandevyver S, Puimege L, Mahieu T et al. LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome. EMBO Mol Med 2013; 5: 456-470.
-
EMBO Mol Med
, vol.2013
, Issue.5
, pp. 456-470
-
-
Pinheiro, I.1
Dejager, L.2
Petta, I.3
Vandevyver, S.4
Puimege, L.5
Mahieu, T.6
-
24
-
-
34249888804
-
GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling
-
Ayroldi E, Zollo O, Bastianelli A, Marchetti C, Agostini M, Di Virgilio R et al. GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling. J Clin Investig 2007; 117: 1605-1615.
-
(2007)
J Clin Investig
, vol.117
, pp. 1605-1615
-
-
Ayroldi, E.1
Zollo, O.2
Bastianelli, A.3
Marchetti, C.4
Agostini, M.5
Di Virgilio, R.6
-
25
-
-
84855475484
-
Long glucocorticoid-induced leucine zipper (L-GILZ) protein interacts with ras protein pathway and contributes to spermatogenesis control
-
Bruscoli S, Velardi E, Di Sante M, Bereshchenko O, Venanzi A, Coppo M et al. Long glucocorticoid-induced leucine zipper (L-GILZ) protein interacts with ras protein pathway and contributes to spermatogenesis control. J Biol Chem 2012; 287: 1242-1251.
-
J Biol Chem
, vol.2012
, Issue.287
, pp. 1242-1251
-
-
Bruscoli, S.1
Velardi, E.2
Di Sante, M.3
Bereshchenko, O.4
Venanzi, A.5
Coppo, M.6
-
26
-
-
3042795223
-
Physiological and pathological consequences of the interactions of the p53 tumor suppressor with the glucocorticoid, androgen, and estrogen receptors
-
Sengupta S, Wasylyk B. Physiological and pathological consequences of the interactions of the p53 tumor suppressor with the glucocorticoid, androgen, and estrogen receptors. Ann NY Acad Sci 2004; 1024: 54-71.
-
(2004)
Ann NY Acad Sci
, vol.1024
, pp. 54-71
-
-
Sengupta, S.1
Wasylyk, B.2
-
27
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993; 362: 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
-
28
-
-
0035103326
-
Glucocorticoids protect against apoptosis induced by serum deprivation, cyclic adenosine 3',5'-monophosphate and p53 activation in immortalized human granulosa cells: Involvement of Bcl-2
-
Sasson R, Tajima K, Amsterdam A. Glucocorticoids protect against apoptosis induced by serum deprivation, cyclic adenosine 3',5'-monophosphate and p53 activation in immortalized human granulosa cells: involvement of Bcl-2. Endocrinology 2001; 142: 802-811.
-
(2001)
Endocrinology
, vol.142
, pp. 802-811
-
-
Sasson, R.1
Tajima, K.2
Amsterdam, A.3
-
29
-
-
0030786527
-
Modulation of hormone-dependent transcriptional activity of the glucocorticoid receptor by the tumor suppressor p53
-
Yu C, Yap N, Chen D, Cheng S. Modulation of hormone-dependent transcriptional activity of the glucocorticoid receptor by the tumor suppressor p53. Cancer Lett 1997; 116: 191-196.
-
(1997)
Cancer Lett
, vol.116
, pp. 191-196
-
-
Yu, C.1
Yap, N.2
Chen, D.3
Cheng, S.4
-
30
-
-
0036275355
-
Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation
-
Crochemore C, Michaelidis TM, Fischer D, Loeffler JP, Almeida OF. Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. FASEB J 2002; 16: 761-770.
-
(2002)
FASEB J
, vol.16
, pp. 761-770
-
-
Crochemore, C.1
Michaelidis, T.M.2
Fischer, D.3
Loeffler, J.P.4
Almeida, O.F.5
-
31
-
-
0038660681
-
Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression
-
Urban G, Golden T, Aragon IV, Cowsert L, Cooper SR, Dean NM et al. Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression. J Biol Chem 2003; 278: 9747-9753.
-
(2003)
J Biol Chem
, vol.278
, pp. 9747-9753
-
-
Urban, G.1
Golden, T.2
Aragon, I.V.3
Cowsert, L.4
Cooper, S.R.5
Dean, N.M.6
-
32
-
-
80054761315
-
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor
-
Murphy SH, Suzuki K, Downes M, Welch GL, De Jesus P, Miraglia LJ et al. Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor. Proc Natl Acad Sci USA 2011; 108: 17117-17122.
-
Proc Natl Acad Sci USA
, vol.2011
, Issue.108
, pp. 17117-17122
-
-
Murphy, S.H.1
Suzuki, K.2
Downes, M.3
Welch, G.L.4
De Jesus, P.5
Miraglia, L.J.6
-
33
-
-
33751252292
-
Direct observation of individual endogenous protein complexes in situ by proximity ligation
-
Soderberg O, Gullberg M, Jarvius M, Ridderstrale K, Leuchowius KJ, Jarvius J et al. Direct observation of individual endogenous protein complexes In situ by proximity ligation. Nat Methods 2006; 3: 995-1000.
-
(2006)
Nat Methods
, vol.3
, pp. 995-1000
-
-
Soderberg, O.1
Gullberg, M.2
Jarvius, M.3
Ridderstrale, K.4
Leuchowius, K.J.5
Jarvius, J.6
-
34
-
-
0034642488
-
P53 is involved in the p120E4F-mediated growth arrest
-
Sandy P, Gostissa M, Fogal V, Cecco LD, Szalay K, Rooney RJ et al. p53 is involved in the p120E4F-mediated growth arrest. Oncogene 2000; 19: 188-199.
-
(2000)
Oncogene
, vol.19
, pp. 188-199
-
-
Sandy, P.1
Gostissa, M.2
Fogal, V.3
Cecco, L.D.4
Szalay, K.5
Rooney, R.J.6
-
35
-
-
0027222956
-
Mapping of the p53 and mdm-2 interaction domains
-
Chen J, Marechal V, Levine AJ. Mapping of the p53 and mdm-2 interaction domains. Mol Cell Biol 1993; 13: 4107-4114.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4107-4114
-
-
Chen, J.1
Marechal, V.2
Levine, A.J.3
-
36
-
-
0033529866
-
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
-
Kudo N, Matsumori N, Taoka H, Fujiwara D, Schreiner EP, Wolff B et al. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci USA 1999; 96: 9112-9117.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9112-9117
-
-
Kudo, N.1
Matsumori, N.2
Taoka, H.3
Fujiwara, D.4
Schreiner, E.P.5
Wolff, B.6
-
37
-
-
0038075338
-
Decision making by p53: Life, death and cancer
-
Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 2003; 10: 431-442.
-
(2003)
Cell Death Differ
, vol.10
, pp. 431-442
-
-
Oren, M.1
-
39
-
-
84891933566
-
Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wildtype p53 breast cancer cells
-
Geng QQ, Dong DF, Chen NZ, Wu YY, Li EX, Wang J et al. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wildtype p53 breast cancer cells. Int J Oncol 2013; 43: 1935-1942.
-
(2013)
Int J Oncol
, vol.43
, pp. 1935-1942
-
-
Geng, Q.Q.1
Dong, D.F.2
Chen, N.Z.3
Wu, Y.Y.4
Li, E.X.5
Wang, J.6
-
40
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997; 387: 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
41
-
-
43949107925
-
SnapShot: P53 posttranslational modifications
-
Kruse JP, Gu W. SnapShot: p53 posttranslational modifications. Cell 2008; 133: 930-930 e931.
-
(2008)
Cell
, vol.133
, pp. 930-930
-
-
Kruse, J.P.1
Gu, W.2
-
42
-
-
0842332406
-
Dynamics of the p53-Mdm2 feedback loop in individual cells
-
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB et al. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet 2004; 36: 147-150.
-
(2004)
Nat Genet
, vol.36
, pp. 147-150
-
-
Lahav, G.1
Rosenfeld, N.2
Sigal, A.3
Geva-Zatorsky, N.4
Levine, A.J.5
Elowitz, M.B.6
-
43
-
-
77449155637
-
The multiple levels of regulation by p53 ubiquitination
-
Lee JT, Gu W. The multiple levels of regulation by p53 ubiquitination. Cell Death Differ 2010; 17: 86-92.
-
Cell Death Differ
, vol.2010
, Issue.17
, pp. 86-92
-
-
Lee, J.T.1
Gu, W.2
-
44
-
-
0031724593
-
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
-
Freedman DA, Levine AJ. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol Cell Biol 1998; 18: 7288-7293.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7288-7293
-
-
Freedman, D.A.1
Levine, A.J.2
-
45
-
-
0348134742
-
Mono- versus polyubiquitination: Differential control of p53 fate by Mdm2
-
Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003; 302: 1972-1975.
-
(2003)
Science
, vol.302
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
46
-
-
18744406282
-
Differentiation of Hdm2- mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors
-
Lai Z, Yang T, Kim YB, Sielecki TM, Diamond MA, Strack P et al. Differentiation of Hdm2- mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors. Proc Natl Acad Sci USA 2002; 99: 14734-14739.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14734-14739
-
-
Lai, Z.1
Yang, T.2
Kim, Y.B.3
Sielecki, T.M.4
Diamond, M.A.5
Strack, P.6
-
47
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998; 92: 725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
48
-
-
36049010619
-
The p53-Mdm2-HAUSP complex is involved in p53 stabilization by HAUSP
-
Brooks CL, Li M, Hu M, Shi Y, Gu W. The p53-Mdm2-HAUSP complex is involved in p53 stabilization by HAUSP. Oncogene 2007; 26: 7262-7266.
-
(2007)
Oncogene
, vol.26
, pp. 7262-7266
-
-
Brooks, C.L.1
Li, M.2
Hu, M.3
Shi, Y.4
Gu, W.5
-
49
-
-
77953099661
-
The tumor suppressor UCHL1 forms a complex with p53/MDM2/ARF to promote p53 signaling and is frequently silenced in nasopharyngeal carcinoma
-
Li L, Tao Q, Jin H, van Hasselt A, Poon FF, Wang X et al. The tumor suppressor UCHL1 forms a complex with p53/MDM2/ARF to promote p53 signaling and is frequently silenced in nasopharyngeal carcinoma. Clin Cancer Res 2010; 16: 2949-2958.
-
Clin Cancer Res
, vol.2010
, Issue.16
, pp. 2949-2958
-
-
Li, L.1
Tao, Q.2
Jin, H.3
Van Hasselt, A.4
Poon, F.F.5
Wang, X.6
-
50
-
-
84864764952
-
Crucial role of TSC-22 in preventing the proteasomal degradation of p53 in cervical cancer
-
Yoon CH, Rho SB, Kim ST, Kho S, Park J, Jang IS et al. Crucial role of TSC-22 in preventing the proteasomal degradation of p53 in cervical cancer. PloS One 2012; 7: e42006.
-
PloS One
, vol.2012
, Issue.7
, pp. e42006
-
-
Yoon, C.H.1
Rho, S.B.2
Kim, S.T.3
Kho, S.4
Park, J.5
Jang, I.S.6
-
51
-
-
38049046724
-
NUMB controls p53 tumour suppressor activity
-
Colaluca IN, Tosoni D, Nuciforo P, Senic-Matuglia F, Galimberti V, Viale G et al. NUMB controls p53 tumour suppressor activity. Nature 2008; 451: 76-80.
-
(2008)
Nature
, vol.451
, pp. 76-80
-
-
Colaluca, I.N.1
Tosoni, D.2
Nuciforo, P.3
Senic-Matuglia, F.4
Galimberti, V.5
Viale, G.6
-
52
-
-
75749132016
-
USP10 regulates p53 localization and stability by deubiquitinating p53
-
Yuan J, Luo K, Zhang L, Cheville JC, Lou Z. USP10 regulates p53 localization and stability by deubiquitinating p53. Cell 2010; 140: 384-396.
-
Cell
, vol.2010
, Issue.140
, pp. 384-396
-
-
Yuan, J.1
Luo, K.2
Zhang, L.3
Cheville, J.C.4
Lou, Z.5
-
53
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ et al. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 1996; 274: 948-953.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
-
54
-
-
33746865877
-
P73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints
-
Wang S, El-Deiry WS. p73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints. Cancer Res 2006; 66: 6982-6989.
-
(2006)
Cancer Res
, vol.66
, pp. 6982-6989
-
-
Wang, S.1
El-Deiry, W.S.2
-
55
-
-
0027286616
-
The tumor suppressor p53 regulates its own transcription
-
Deffie A, Wu H, Reinke V, Lozano G. The tumor suppressor p53 regulates its own transcription. Mol Cell Biol 1993; 13: 3415-3423.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3415-3423
-
-
Deffie, A.1
Wu, H.2
Reinke, V.3
Lozano, G.4
-
56
-
-
0033592868
-
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
-
Khosravi R, Maya R, Gottlieb T, Oren M, Shiloh Y, Shkedy D. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. Proc Natl Acad Sci USA 1999; 96: 14973-14977.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14973-14977
-
-
Khosravi, R.1
Maya, R.2
Gottlieb, T.3
Oren, M.4
Shiloh, Y.5
Shkedy, D.6
-
57
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Investig 1999; 104: 263-269.
-
(1999)
J Clin Investig
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
-
58
-
-
84859381463
-
A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53
-
Zhang Q, Zeng SX, Zhang Y, Zhang Y, Ding D, Ye Q et al. A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53. EMBO Mol Med 2012; 4: 298-312.
-
EMBO Mol Med
, vol.2012
, Issue.4
, pp. 298-312
-
-
Zhang, Q.1
Zeng, S.X.2
Zhang, Y.3
Zhang, Y.4
Ding, D.5
Ye, Q.6
-
59
-
-
0036840376
-
Glucocorticoidinduced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1
-
Ayroldi E, Zollo O, Macchiarulo A, Di Marco B, Marchetti C, Riccardi C. Glucocorticoidinduced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1. Mol Cell Biol 2002; 22: 7929-7941.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7929-7941
-
-
Ayroldi, E.1
Zollo, O.2
Macchiarulo, A.3
Di Marco, B.4
Marchetti, C.5
Riccardi, C.6
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