Crucial role of TSC-22 in preventing the proteasomal degradation of p53 in cervical cancer

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Yoon, Cheol Hee ^b   Rho, Seung Bae ^c   Kim, Seong Tae ^a   Kho, Seongho ^a   Park, Junsoo ^d   Jang, Ik Soon ^e   Woo, Seonock ^f   Kim, Sung Soon ^b   Lee, Je Ho ^g   Lee, Seung Hoon ^a  

^a Yongin University   (South Korea)

^b Korea National Institute of Health   (South Korea)

^c National Cancer Center   (South Korea)

^d Yonsei University Wonju   (South Korea)

^e Korea Basic Science Institute (KBSI)   (South Korea)

^f Korea Research Institute of Ships and Ocean Engineering   (South Korea)

^g Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN E6; PROTEIN MDM2; PROTEIN P53; PUMA PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA2; TSC 22; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG STABILITY; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; UBIQUITINATION; UTERINE CERVIX CANCER;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MDM2; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS; MUS;

EID: 84864764952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042006     Document Type: Article

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