메뉴 건너뛰기




Volumn 6, Issue MAR, 2015, Pages

Identification of agonists for a group of human odorant receptors

Author keywords

Functional screening; GPCRs; Heterologous expression; Human odorant receptor; Human olfactory receptor; Odorant perception; Odorants; Orphan receptors

Indexed keywords

G PROTEIN COUPLED RECEPTOR; ODORANT RECEPTOR; UNCLASSIFIED DRUG; VOLATILE AGENT;

EID: 84926469436     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00035     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 0029939849 scopus 로고    scopus 로고
    • Information coding in the vertebrate olfactory system
    • Buck, L. (1996). Information coding in the vertebrate olfactory system. Annu. Rev. Neurosci. 19, 517-544. doi: 10.1146/annurev.ne.19.030196.002505.
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 517-544
    • Buck, L.1
  • 2
    • 0025825726 scopus 로고
    • A novel multigene family may encode odorant receptors: a molecular basis for odor recognition
    • Buck, L., and Axel, R. (1991). A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65, 175-187. doi: 10.1016/0092-8674(91)90418-X.
    • (1991) Cell , vol.65 , pp. 175-187
    • Buck, L.1    Axel, R.2
  • 3
    • 84896986083 scopus 로고    scopus 로고
    • Humans can discriminate more than 1 trillion olfactory stimuli
    • Bushdid, C., Magnasco, M. O., Vosshall, L. B., and Keller, A. (2014). Humans can discriminate more than 1 trillion olfactory stimuli. Science 343, 1370-1372. doi: 10.1126/science.1249168.
    • (2014) Science , vol.343 , pp. 1370-1372
    • Bushdid, C.1    Magnasco, M.O.2    Vosshall, L.B.3    Keller, A.4
  • 4
    • 84908567248 scopus 로고    scopus 로고
    • A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4
    • Busse, D., Kudella, P., Gruning, N. M., Gisselmann, G., Stander, S., Luger, T., et al. (2014). A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4. J. Invest. Dermatol. 134, 2823-2832. doi: 10.1038/jid.2014.273.
    • (2014) J. Invest. Dermatol. , vol.134 , pp. 2823-2832
    • Busse, D.1    Kudella, P.2    Gruning, N.M.3    Gisselmann, G.4    Stander, S.5    Luger, T.6
  • 5
    • 84903745919 scopus 로고    scopus 로고
    • Nature's chemical signatures in human olfaction: a foodborne perspective for future biotechnology
    • Dunkel, A., Steinhaus, M., Kotthoff, M., Nowak, B., Krautwurst, D., Schieberle, P., et al. (2014). Nature's chemical signatures in human olfaction: a foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 53, 7124-7143. doi: 10.1002/anie.201309508.
    • (2014) Angew. Chem. Int. Ed. Engl. , vol.53 , pp. 7124-7143
    • Dunkel, A.1    Steinhaus, M.2    Kotthoff, M.3    Nowak, B.4    Krautwurst, D.5    Schieberle, P.6
  • 6
    • 0034633263 scopus 로고    scopus 로고
    • A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture
    • Durocher, Y., Perret, S., Thibaudeau, E., Gaumond, M. H., Kamen, A., Stocco, R., et al. (2000). A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture. Anal. Biochem. 284, 316-326. doi: 10.1006/abio.2000.4698.
    • (2000) Anal. Biochem. , vol.284 , pp. 316-326
    • Durocher, Y.1    Perret, S.2    Thibaudeau, E.3    Gaumond, M.H.4    Kamen, A.5    Stocco, R.6
  • 7
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
    • Guindon, S., Dufayard, J. F., Lefort, V., Anisimova, M., Hordijk, W., and Gascuel, O. (2010). New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst. Biol. 59, 307-321. doi: 10.1093/sysbio/syq010.
    • (2010) Syst. Biol. , vol.59 , pp. 307-321
    • Guindon, S.1    Dufayard, J.F.2    Lefort, V.3    Anisimova, M.4    Hordijk, W.5    Gascuel, O.6
  • 8
    • 84882618934 scopus 로고    scopus 로고
    • A Mendelian trait for olfactory sensitivity affects odor experience and food selection
    • Jaeger, S. R., McRae, J. F., Bava, C. M., Beresford, M. K., Hunter, D., Jia, Y., et al. (2013). A Mendelian trait for olfactory sensitivity affects odor experience and food selection. Curr. Biol. 23, 1601-1605. doi: 10.1016/j.cub.2013.07.030.
    • (2013) Curr. Biol. , vol.23 , pp. 1601-1605
    • Jaeger, S.R.1    McRae, J.F.2    Bava, C.M.3    Beresford, M.K.4    Hunter, D.5    Jia, Y.6
  • 9
    • 33645314929 scopus 로고    scopus 로고
    • Characterization of an extended receptive ligand repertoire of the human olfactory receptor OR17-40 comprising structurally related compounds
    • Jaquier, V., Pick, H., and Vogel, H. (2006). Characterization of an extended receptive ligand repertoire of the human olfactory receptor OR17-40 comprising structurally related compounds. J. Neurochem. 97, 537-544. doi: 10.1111/j.1471-4159.2006.03771.x.
    • (2006) J. Neurochem. , vol.97 , pp. 537-544
    • Jaquier, V.1    Pick, H.2    Vogel, H.3
  • 10
    • 0024475378 scopus 로고
    • Golf: an olfactory neuron-specific G-protein involved in odorant signal transduction
    • Jones, D. T., and Reed, R. R. (1989). Golf: an olfactory neuron-specific G-protein involved in odorant signal transduction. Science 244, 790-795. doi: 10.1126/science.2499043.
    • (1989) Science , vol.244 , pp. 790-795
    • Jones, D.T.1    Reed, R.R.2
  • 11
    • 34848899273 scopus 로고    scopus 로고
    • Genetic variation in a human odorant receptor alters odour perception
    • Keller, A., Zhuang, H., Chi, Q., Vosshall, L., and Matsunami, H. (2007). Genetic variation in a human odorant receptor alters odour perception. Nature 449, 468-472. doi: 10.1038/nature06162.
    • (2007) Nature , vol.449 , pp. 468-472
    • Keller, A.1    Zhuang, H.2    Chi, Q.3    Vosshall, L.4    Matsunami, H.5
  • 12
    • 0036226603 scopus 로고    scopus 로고
    • BLAT-the BLAST-like alignment tool
    • Kent, W. J. (2002). BLAT-the BLAST-like alignment tool. Genome. Res. 12, 656-664. doi: 10.1101/gr.229202.
    • (2002) Genome. Res. , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 14
    • 0032417641 scopus 로고    scopus 로고
    • Identification of ligands for olfactory receptors by functional expression of a receptor library
    • Krautwurst, D., Yau, K. W., and Reed, R. R. (1998). Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 95, 917-926. doi: 10.1016/S0092-8674(00)81716-X.
    • (1998) Cell , vol.95 , pp. 917-926
    • Krautwurst, D.1    Yau, K.W.2    Reed, R.R.3
  • 15
    • 33846056843 scopus 로고    scopus 로고
    • Entrez Gene: gene-centered information at NCBI
    • Maglott, D., Ostell, J., Pruitt, K. D., and Tatusova, T. (2007). Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 35, D26-D31. doi: 10.1093/nar/gkl993.
    • (2007) Nucleic Acids Res. , vol.35 , pp. D26-D31
    • Maglott, D.1    Ostell, J.2    Pruitt, K.D.3    Tatusova, T.4
  • 16
    • 84892455634 scopus 로고    scopus 로고
    • The missense of smell: functional variability in the human odorant receptor repertoire
    • Mainland, J. D., Keller, A., Li, Y. R., Zhou, T., Trimmer, C., Snyder, L. L., et al. (2014). The missense of smell: functional variability in the human odorant receptor repertoire. Nat. Neurosci. 17, 114-120. doi: 10.1038/nn.3598.
    • (2014) Nat. Neurosci. , vol.17 , pp. 114-120
    • Mainland, J.D.1    Keller, A.2    Li, Y.R.3    Zhou, T.4    Trimmer, C.5    Snyder, L.L.6
  • 17
    • 36249005993 scopus 로고    scopus 로고
    • Searching for the ligands of odorant receptors
    • Malnic, B. (2007). Searching for the ligands of odorant receptors. Mol. Neurobiol. 35, 175-181. doi: 10.1007/s12035-007-0013-2.
    • (2007) Mol. Neurobiol. , vol.35 , pp. 175-181
    • Malnic, B.1
  • 18
    • 1442281343 scopus 로고    scopus 로고
    • The human olfactory receptor gene family
    • Malnic, B., Godfrey, P. A., and Buck, L. B. (2004). The human olfactory receptor gene family. Proc. Natl. Acad. Sci. U.S.A. 101, 2584-2589. doi: 10.1073/pnas.0307882100.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 2584-2589
    • Malnic, B.1    Godfrey, P.A.2    Buck, L.B.3
  • 19
    • 68649109842 scopus 로고    scopus 로고
    • Functional expression of chemoreceptors with the help of a Guanine nucleotide exchange factor
    • Malnic, B., and Gonzalez-Kristeller, D. C. (2009). Functional expression of chemoreceptors with the help of a Guanine nucleotide exchange factor. Ann. N.Y. Acad. Sci. 1170, 150-152. doi: 10.1111/j.1749-6632.2009.03874.x.
    • (2009) Ann. N.Y. Acad. Sci. , vol.1170 , pp. 150-152
    • Malnic, B.1    Gonzalez-Kristeller, D.C.2
  • 20
    • 0033525727 scopus 로고    scopus 로고
    • Combinatorial receptor codes for odors
    • Malnic, B., Hirono, J., Sato, T., and Buck, L. B. (1999). Combinatorial receptor codes for odors. Cell 96, 713-723. doi: 10.1016/S0092-8674(00)80581-4.
    • (1999) Cell , vol.96 , pp. 713-723
    • Malnic, B.1    Hirono, J.2    Sato, T.3    Buck, L.B.4
  • 21
    • 22844434585 scopus 로고    scopus 로고
    • Functional characterization of two human olfactory receptors expressed in the baculovirus Sf9 insect cell system
    • Matarazzo, V., Clo-Faybesse, O., Marcet, B., Guiraudie-Capraz, G., Atanasova, B., Devauchelle, G., et al. (2005). Functional characterization of two human olfactory receptors expressed in the baculovirus Sf9 insect cell system. Chem. Senses 30, 195-207. doi: 10.1093/chemse/bji015.
    • (2005) Chem. Senses , vol.30 , pp. 195-207
    • Matarazzo, V.1    Clo-Faybesse, O.2    Marcet, B.3    Guiraudie-Capraz, G.4    Atanasova, B.5    Devauchelle, G.6
  • 22
    • 84911369871 scopus 로고    scopus 로고
    • In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors
    • McClintock, T. S., Adipietro, K., Titlow, W. B., Breheny, P., Walz, A., Mombaerts, P., et al. (2014). In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors. J. Neurosci. 34, 15669-15678. doi: 10.1523/JNEUROSCI.3625-14.2014.
    • (2014) J. Neurosci. , vol.34 , pp. 15669-15678
    • McClintock, T.S.1    Adipietro, K.2    Titlow, W.B.3    Breheny, P.4    Walz, A.5    Mombaerts, P.6
  • 23
    • 37249038498 scopus 로고    scopus 로고
    • Genetic elucidation of human hyperosmia to isovaleric acid
    • Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C., et al. (2007). Genetic elucidation of human hyperosmia to isovaleric acid. PLoS Biol. 5:e284. doi: 10.1371/journal.pbio.0050284.
    • (2007) PLoS Biol. , vol.5
    • Menashe, I.1    Abaffy, T.2    Hasin, Y.3    Goshen, S.4    Yahalom, V.5    Luetje, C.6
  • 24
    • 1842464122 scopus 로고    scopus 로고
    • Genes and ligands for odorant, vomeronasal and taste receptors
    • Mombaerts, P. (2004). Genes and ligands for odorant, vomeronasal and taste receptors. Nat. Rev. Neurosci. 5, 263-278. doi: 10.1038/nrn1365.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 263-278
    • Mombaerts, P.1
  • 25
    • 79959669711 scopus 로고    scopus 로고
    • A large-scale analysis of odor coding in the olfactory epithelium
    • Nara, K., Saraiva, L. R., Ye, X., and Buck, L. B. (2011). A large-scale analysis of odor coding in the olfactory epithelium. J. Neurosci. 31, 9179-9191. doi: 10.1523/JNEUROSCI.1282-11.2011.
    • (2011) J. Neurosci. , vol.31 , pp. 9179-9191
    • Nara, K.1    Saraiva, L.R.2    Ye, X.3    Buck, L.B.4
  • 26
    • 33745523360 scopus 로고    scopus 로고
    • A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins
    • Neuhaus, E., Mashukova, A., Zhang, W., Barbour, J., and Hatt, H. (2006). A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins. Chem. Senses 31, 445-452. doi: 10.1093/chemse/bjj049.
    • (2006) Chem. Senses , vol.31 , pp. 445-452
    • Neuhaus, E.1    Mashukova, A.2    Zhang, W.3    Barbour, J.4    Hatt, H.5
  • 27
    • 84899514272 scopus 로고    scopus 로고
    • The state of the art of odorant receptor deorphanization: a report from the orphanage
    • Peterlin, Z., Firestein, S., and Rogers, M. E. (2014). The state of the art of odorant receptor deorphanization: a report from the orphanage. J. Gen. Physiol. 143, 527-542. doi: 10.1085/jgp.201311151.
    • (2014) J. Gen. Physiol. , vol.143 , pp. 527-542
    • Peterlin, Z.1    Firestein, S.2    Rogers, M.E.3
  • 28
    • 84991494823 scopus 로고    scopus 로고
    • 'Signal transduction in vertebrate olfactory Cilia'
    • ed A. Menini (Boca Raton, FL: CRC Press; Taylor and Francis Group)
    • Pifferi, S., Menini, A., and Kurahashi, T. (2010). "Signal transduction in vertebrate olfactory Cilia," in The Neurobiology of Olfaction, Chapter 8, ed A. Menini (Boca Raton, FL: CRC Press; Taylor and Francis Group), 203-224.
    • (2010) The Neurobiology of Olfaction, Chapter 8 , pp. 203-224
    • Pifferi, S.1    Menini, A.2    Kurahashi, T.3
  • 30
    • 8844270180 scopus 로고    scopus 로고
    • RTP family members induce functional expression of mammalian odorant receptors
    • Saito, H., Kubota, M., Roberts, R. W., Chi, Q., and Matsunami, H. (2004). RTP family members induce functional expression of mammalian odorant receptors. Cell 119, 679-691. doi: 10.1016/j.cell.2004.11.021.
    • (2004) Cell , vol.119 , pp. 679-691
    • Saito, H.1    Kubota, M.2    Roberts, R.W.3    Chi, Q.4    Matsunami, H.5
  • 31
    • 22344436740 scopus 로고    scopus 로고
    • Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism
    • Sanz, G., Schlegel, C., Pernollet, J.-C., and Briand, L. (2005). Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism. Chem. Senses 30, 69-80. doi: 10.1093/chemse/bji002.
    • (2005) Chem. Senses , vol.30 , pp. 69-80
    • Sanz, G.1    Schlegel, C.2    Pernollet, J.-C.3    Briand, L.4
  • 32
    • 34547881027 scopus 로고    scopus 로고
    • Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2
    • Schmiedeberg, K., Shirokova, E., Weber, H., Schilling, B., Meyerhof, W., and Krautwurst, D. (2007). Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2. J. Struct. Biol. 159, 400-412. doi: 10.1016/j.jsb.2007.04.013.
    • (2007) J. Struct. Biol. , vol.159 , pp. 400-412
    • Schmiedeberg, K.1    Shirokova, E.2    Weber, H.3    Schilling, B.4    Meyerhof, W.5    Krautwurst, D.6
  • 33
    • 84891828705 scopus 로고    scopus 로고
    • Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors
    • Shirasu, M., Yoshikawa, K., Takai, Y., Nakashima, A., Takeuchi, H., Sakano, H., et al. (2014). Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors. Neuron 81, 165-178. doi: 10.1016/j.neuron.2013.10.021.
    • (2014) Neuron , vol.81 , pp. 165-178
    • Shirasu, M.1    Yoshikawa, K.2    Takai, Y.3    Nakashima, A.4    Takeuchi, H.5    Sakano, H.6
  • 34
    • 84900542890 scopus 로고    scopus 로고
    • Profiling of olfactory receptor gene expression in whole human olfactory mucosa
    • Verbeurgt, C., Wilkin, F., Tarabichi, M., Gregoire, F., Dumont, J. E., and Chatelain, P. (2014). Profiling of olfactory receptor gene expression in whole human olfactory mucosa. PLoS ONE 9:e96333. doi: 10.1371/journal.pone.0096333.
    • (2014) PLoS ONE , vol.9
    • Verbeurgt, C.1    Wilkin, F.2    Tarabichi, M.3    Gregoire, F.4    Dumont, J.E.5    Chatelain, P.6
  • 35
    • 17644404436 scopus 로고    scopus 로고
    • Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Gaolf
    • Von Dannecker, L., Mercadante, A., and Malnic, B. (2005). Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Gaolf. J. Neurosci. 25, 3793-3800. doi: 10.1523/JNEUROSCI.4595-04.2005.
    • (2005) J. Neurosci. , vol.25 , pp. 3793-3800
    • Von Dannecker, L.1    Mercadante, A.2    Malnic, B.3
  • 36
    • 33745139081 scopus 로고    scopus 로고
    • Ric-8B promotes functional expression of odorant receptors
    • Von Dannecker, L., Mercadante, A., and Malnic, B. (2006). Ric-8B promotes functional expression of odorant receptors. Proc. Natl. Acad. Sci. U.S.A. 103, 9310-9314. doi: 10.1073/pnas.0600697103.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 9310-9314
    • Von Dannecker, L.1    Mercadante, A.2    Malnic, B.3
  • 37
    • 0033198254 scopus 로고    scopus 로고
    • Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus Laevis oocytes
    • Wetzel, C. H., Oles, M., Wellerdieck, C., Kuczkowiak, M., and Hatt, H. (1999). Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus Laevis oocytes. J. Neurosci. 19, 7426-7433.
    • (1999) J. Neurosci. , vol.19 , pp. 7426-7433
    • Wetzel, C.H.1    Oles, M.2    Wellerdieck, C.3    Kuczkowiak, M.4    Hatt, H.5
  • 38
    • 34447549293 scopus 로고    scopus 로고
    • Synergism of accessory factors in functional expression of mammalian odorant receptors
    • Zhuang, H., and Matsunami, H. (2007). Synergism of accessory factors in functional expression of mammalian odorant receptors. J. Biol. Chem. 282, 15284-15293. doi: 10.1074/jbc.M700386200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15284-15293
    • Zhuang, H.1    Matsunami, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.