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Volumn 159, Issue 3, 2007, Pages 400-412

Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2

Author keywords

Docking model; Human; Mutation; Odorant; Olfactory receptors; Orthologs

Indexed keywords

CITRONELLAL; CITRONELLOL; OLFACTORY RECEPTOR OR1A1; OLFACTORY RECEPTOR OR1A2; RECEPTOR; RHODOPSIN; UNCLASSIFIED DRUG;

EID: 34547881027     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2007.04.013     Document Type: Article
Times cited : (134)

References (32)
  • 1
    • 34548340978 scopus 로고    scopus 로고
    • The molecular basis for ligand specificity in a mouse olfactory receptor: A network of functionally important residues
    • Abaffy T., Malhotra A., and Luetje C.W. The molecular basis for ligand specificity in a mouse olfactory receptor: A network of functionally important residues. J. Biol. Chem. 17 (2006) 17
    • (2006) J. Biol. Chem. , vol.17 , pp. 17
    • Abaffy, T.1    Malhotra, A.2    Luetje, C.W.3
  • 2
    • 18344398255 scopus 로고    scopus 로고
    • Towards structural models of molecular recognition in olfactory receptors
    • Afshar M., Hubbard R.E., and Demaille J. Towards structural models of molecular recognition in olfactory receptors. Biochimie 80 (1998) 129-135
    • (1998) Biochimie , vol.80 , pp. 129-135
    • Afshar, M.1    Hubbard, R.E.2    Demaille, J.3
  • 3
    • 1642524949 scopus 로고    scopus 로고
    • A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium
    • Epub 2004 Jan 14
    • Araneda R.C., Peterlin Z., Zhang X., Chesler A., and Firestein S. A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium. J. Physiol. 555 (2004) 743-756 Epub 2004 Jan 14
    • (2004) J. Physiol. , vol.555 , pp. 743-756
    • Araneda, R.C.1    Peterlin, Z.2    Zhang, X.3    Chesler, A.4    Firestein, S.5
  • 5
    • 0031616705 scopus 로고    scopus 로고
    • Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB
    • Gerber P.R. Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB. J. Comput. Aided Mol. Des. 12 (1998) 37-51
    • (1998) J. Comput. Aided Mol. Des. , vol.12 , pp. 37-51
    • Gerber, P.R.1
  • 7
    • 0034955778 scopus 로고    scopus 로고
    • Evaluation of the key odorants of foods by dilution experiments, aroma models and omission
    • Grosch W. Evaluation of the key odorants of foods by dilution experiments, aroma models and omission. Chem Senses 26 (2001) 533-545
    • (2001) Chem Senses , vol.26 , pp. 533-545
    • Grosch, W.1
  • 8
    • 14144249986 scopus 로고    scopus 로고
    • Predicted 3-d structures for mouse i7 and rat i7 olfactory receptors and comparison of predicted odor recognition profiles with experiment
    • Hall S.E., Floriano W.B., Vaidehi N., and Goddard III W.A. Predicted 3-d structures for mouse i7 and rat i7 olfactory receptors and comparison of predicted odor recognition profiles with experiment. Chem Senses 29 (2004) 595-616
    • (2004) Chem Senses , vol.29 , pp. 595-616
    • Hall, S.E.1    Floriano, W.B.2    Vaidehi, N.3    Goddard III, W.A.4
  • 9
    • 14144253386 scopus 로고    scopus 로고
    • Test of the binding threshold hypothesis for olfactory receptors: explanation of the differential binding of ketones to the mouse and human orthologs of olfactory receptor 912-93
    • Hummel P., Vaidehi N., Floriano W.B., Hall S.E., and Goddard III W.A. Test of the binding threshold hypothesis for olfactory receptors: explanation of the differential binding of ketones to the mouse and human orthologs of olfactory receptor 912-93. Protein Sci. 14 (2005) 703-710
    • (2005) Protein Sci. , vol.14 , pp. 703-710
    • Hummel, P.1    Vaidehi, N.2    Floriano, W.B.3    Hall, S.E.4    Goddard III, W.A.5
  • 10
    • 14044270215 scopus 로고    scopus 로고
    • Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: mapping the odorant-binding site
    • Katada S., Hirokawa T., Oka Y., Suwa M., and Touhara K. Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: mapping the odorant-binding site. J. Neurosci. 25 (2005) 1806-1815
    • (2005) J. Neurosci. , vol.25 , pp. 1806-1815
    • Katada, S.1    Hirokawa, T.2    Oka, Y.3    Suwa, M.4    Touhara, K.5
  • 11
    • 0026602063 scopus 로고
    • Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function
    • Khorana H.G. Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function. J. Biol. Chem. 267 (1992) 1-4
    • (1992) J. Biol. Chem. , vol.267 , pp. 1-4
    • Khorana, H.G.1
  • 12
    • 26944485524 scopus 로고    scopus 로고
    • An automated system for the analysis of G protein-coupled receptor transmembrane binding pockets: alignment, receptor-based pharmacophores, and their application
    • Kratochwil N.A., Malherbe P., Lindemann L., Ebeling M., Hoener M.C., Muhlemann A., Porter R.H., Stahl M., and Gerber P.R. An automated system for the analysis of G protein-coupled receptor transmembrane binding pockets: alignment, receptor-based pharmacophores, and their application. J. Chem. Inf. Model 45 (2005) 1324-1336
    • (2005) J. Chem. Inf. Model , vol.45 , pp. 1324-1336
    • Kratochwil, N.A.1    Malherbe, P.2    Lindemann, L.3    Ebeling, M.4    Hoener, M.C.5    Muhlemann, A.6    Porter, R.H.7    Stahl, M.8    Gerber, P.R.9
  • 13
    • 0032417641 scopus 로고    scopus 로고
    • Identification of ligands for olfactory receptors by functional expression of a receptor library
    • Krautwurst D., Yau K.W., and Reed R.R. Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 95 (1998) 917-926
    • (1998) Cell , vol.95 , pp. 917-926
    • Krautwurst, D.1    Yau, K.W.2    Reed, R.R.3
  • 14
    • 27944475233 scopus 로고    scopus 로고
    • Structural activation pathways from dynamic olfactory receptor-odorant interactions
    • Lai P.C., Singer M.S., and Crasto C.J. Structural activation pathways from dynamic olfactory receptor-odorant interactions. Chem. Senses 30 (2005) 781-792
    • (2005) Chem. Senses , vol.30 , pp. 781-792
    • Lai, P.C.1    Singer, M.S.2    Crasto, C.J.3
  • 16
    • 0037404760 scopus 로고    scopus 로고
    • Motif-based construction of a functional map for mammalian olfactory receptors
    • Liu A.H., Zhang X., Stolovitzky G.A., Califano A., and Firestein S.J. Motif-based construction of a functional map for mammalian olfactory receptors. Genomics 81 (2003) 443-456
    • (2003) Genomics , vol.81 , pp. 443-456
    • Liu, A.H.1    Zhang, X.2    Stolovitzky, G.A.3    Califano, A.4    Firestein, S.J.5
  • 18
    • 0033525727 scopus 로고    scopus 로고
    • Combinatorial receptor codes for odors
    • Malnic B., Hirono J., Sato T., and Buck L.B. Combinatorial receptor codes for odors. Cell 96 (1999) 713-723
    • (1999) Cell , vol.96 , pp. 713-723
    • Malnic, B.1    Hirono, J.2    Sato, T.3    Buck, L.B.4
  • 19
    • 0346102906 scopus 로고    scopus 로고
    • Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons
    • Man O., Gilad Y., and Lancet D. Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons. Protein Sci. 13 (2004) 240-254
    • (2004) Protein Sci. , vol.13 , pp. 240-254
    • Man, O.1    Gilad, Y.2    Lancet, D.3
  • 20
    • 0037305047 scopus 로고    scopus 로고
    • Principles: extending the utility of Trends
    • Milligan G. Principles: extending the utility of Trends. Pharmacol. Sci. 24 (2003) 87-90
    • (2003) Pharmacol. Sci. , vol.24 , pp. 87-90
    • Milligan, G.1
  • 21
    • 0142091376 scopus 로고    scopus 로고
    • Evolution of olfactory receptor genes in the human genome
    • Niimura Y., and Nei M. Evolution of olfactory receptor genes in the human genome. Proc. Natl. Acad. Sci. USA 100 (2003) 12235-12240
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12235-12240
    • Niimura, Y.1    Nei, M.2
  • 22
    • 14644389485 scopus 로고    scopus 로고
    • The olfactory receptor universe - from whole genome analysis to structure and evolution
    • Olender T., Feldmesser E., Atarot T., Eisenstein M., and Lancet D. The olfactory receptor universe - from whole genome analysis to structure and evolution. Genet Mol. Res. 3 (2004) 545-553
    • (2004) Genet Mol. Res. , vol.3 , pp. 545-553
    • Olender, T.1    Feldmesser, E.2    Atarot, T.3    Eisenstein, M.4    Lancet, D.5
  • 24
    • 0032900495 scopus 로고    scopus 로고
    • The variable and conserved interfaces of modeled olfactory receptor proteins
    • Pilpel Y., and Lancet D. The variable and conserved interfaces of modeled olfactory receptor proteins. Protein Sci. 8 (1999) 969-977
    • (1999) Protein Sci. , vol.8 , pp. 969-977
    • Pilpel, Y.1    Lancet, D.2
  • 25
    • 15744387796 scopus 로고    scopus 로고
    • Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants
    • Epub 2004 Dec 14
    • Shirokova E., Schmiedeberg K., Bedner P., Niessen H., Willecke K., Raguse J.D., Meyerhof W., and Krautwurst D. Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. J. Biol. Chem. 280 (2005) 11807-11815 Epub 2004 Dec 14
    • (2005) J. Biol. Chem. , vol.280 , pp. 11807-11815
    • Shirokova, E.1    Schmiedeberg, K.2    Bedner, P.3    Niessen, H.4    Willecke, K.5    Raguse, J.D.6    Meyerhof, W.7    Krautwurst, D.8
  • 26
    • 0034042247 scopus 로고    scopus 로고
    • Analysis of the molecular basis for octanal interactions in the expressed rat 17 olfactory receptor
    • Singer M.S. Analysis of the molecular basis for octanal interactions in the expressed rat 17 olfactory receptor. Chem. Senses 25 (2000) 155-165
    • (2000) Chem. Senses , vol.25 , pp. 155-165
    • Singer, M.S.1
  • 27
    • 0030453906 scopus 로고    scopus 로고
    • Positive selection moments identify potential functional residues in human olfactory receptors
    • Singer M.S., Weisinger-Lewin Y., Lancet D., and Shepherd G.M. Positive selection moments identify potential functional residues in human olfactory receptors. Receptors and Channels 4 (1996) 141-147
    • (1996) Receptors and Channels , vol.4 , pp. 141-147
    • Singer, M.S.1    Weisinger-Lewin, Y.2    Lancet, D.3    Shepherd, G.M.4
  • 29
    • 0014428724 scopus 로고
    • The molecular basis of visual excitation
    • Wald G. The molecular basis of visual excitation. Nature 219 (1968) 800-807
    • (1968) Nature , vol.219 , pp. 800-807
    • Wald, G.1
  • 30
    • 1542779650 scopus 로고    scopus 로고
    • Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels
    • Epub 2003 Oct 7
    • Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., and Trask B.J. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Genome Biol. 4 (2003) R71 Epub 2003 Oct 7
    • (2003) Genome Biol. , vol.4
    • Young, J.M.1    Shykind, B.M.2    Lane, R.P.3    Tonnes-Priddy, L.4    Ross, J.A.5    Walker, M.6    Williams, E.M.7    Trask, B.J.8
  • 31
    • 0036163689 scopus 로고    scopus 로고
    • The olfactory receptor gene superfamily of the mouse
    • Zhang X., and Firestein S. The olfactory receptor gene superfamily of the mouse. Nat. Neurosci. 5 (2002) 124-133
    • (2002) Nat. Neurosci. , vol.5 , pp. 124-133
    • Zhang, X.1    Firestein, S.2
  • 32
    • 0035237870 scopus 로고    scopus 로고
    • The human olfactory receptor repertoire
    • RESEARCH0018
    • Zozulya S., Echeverri F., and Nguyen T. The human olfactory receptor repertoire. Genome Biol. 2 (2001) RESEARCH0018
    • (2001) Genome Biol. , vol.2
    • Zozulya, S.1    Echeverri, F.2    Nguyen, T.3


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